Cureus最新文献

{"title":"EEG-Based Evidence for Belief Coding Therapy in Treating Mental Disorders: A Cross-Sectional Interventional Study.","authors":"Abhijeet Satani, Param Barodia","doi":"10.7759/cureus.93713","DOIUrl":"10.7759/cureus.93713","url":null,"abstract":"<p><strong>Background: </strong>Mental health disorders such as anxiety, depression, panic attacks, and trauma-related conditions are rising globally, presenting a significant public health challenge. Conventional treatments such as cognitive behavioural therapy (CBT) and pharmacological interventions offer symptom relief but often fail to address the underlying subconscious beliefs that perpetuate long-term emotional suffering. Belief Coding®, a novel neuropsychological therapy, was developed to identify and reprogram such limiting subconscious beliefs.</p><p><strong>Methods: </strong>This study was a single-arm, mixed-methods investigation. A total of 75 participants diagnosed with anxiety, depression, or panic disorders were treated using Belief Coding®. Clinical outcomes were assessed with validated measures (GAD-7 (Generalized Anxiety Disorder-7), PHQ-9 (Patient Health Questionnaire-9), PDSS (Panic Disorder Severity Scale)), while neurophysiological changes were monitored via electroencephalography (EEG). The intervention included a structured, single-session protocol (~78 minutes) incorporating memory reconsolidation and multisensory anchoring.</p><p><strong>Results: </strong>Significant symptom reductions were observed: GAD-7 anxiety scores decreased by 54.9%, PHQ-9 depression scores decreased by 51.6%, and PDSS panic disorder scores decreased by 59.4% (all p < .001). EEG findings revealed normalised frontal beta activity, enhanced theta-gamma coupling, and improved interhemispheric coherence (0.51 → 0.78) during memory reconsolidation. At 4-week follow-up, 69.3% of participants achieved full remission, and 90.7% demonstrated clinically significant improvement, often following a single session. Strong correlations were found between neurophysiological improvements and clinical outcomes (r = .73, p < .001).</p><p><strong>Conclusion: </strong>Belief Coding® demonstrates robust clinical efficacy and measurable neurophysiological changes, supporting its validity as an evidence-based therapeutic approach. Its rapid and durable outcomes, combined with a standardised and client-centred protocol, highlight its potential as a scalable treatment option addressing the root causes of psychological distress.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"e93713"},"PeriodicalIF":1.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: The Application of Mesenchymal Stem Cell Therapy in Treating Pulmonary Fibrosis: A Scoping Review.","authors":"Elena Silverstein, Michael Richmann, Delaney Tyl, Ashley Fiaoni, Kylie Pfeifer, Hadi Moussa, Alysia Treacy, Mathew Vigliotta, Michael Schepps, Reena Sheth, Patrick Barry","doi":"10.7759/cureus.c338","DOIUrl":"https://doi.org/10.7759/cureus.c338","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.7759/cureus.74611.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"c338"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delayed Hemolytic Transfusion Reaction With Acute Kidney Injury Due to Anti-E Antibody in a 43-Year-Old Woman With Iron-Deficiency Anemia.","authors":"Kushal Panja, Rajeev Upreti","doi":"10.7759/cureus.93634","DOIUrl":"10.7759/cureus.93634","url":null,"abstract":"<p><p>Delayed hemolytic transfusion reactions (DHTRs) are uncommon yet serious complications of blood transfusion and are often underdiagnosed in patients with negative pre-transfusion antibody screens and a negative direct antiglobulin test (DAT). We report a case of a 43-year-old woman with iron-deficiency anemia secondary to menorrhagia who developed a DHTR with acute kidney injury following red blood cell transfusion. Despite a negative pre-transfusion antibody screen and DAT, she developed hemolysis and renal dysfunction approximately one week post-transfusion; the reference laboratory later identified anti-E antibodies. This case highlights the diagnostic challenges of DHTRs when pre-transfusion serology and DAT are negative. Vigilant clinical suspicion and post-transfusion monitoring are crucial to prevent and manage potentially life-threatening complications.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"e93634"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: A Systematic Review of Perinuclear Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis Following Coronavirus Disease 2019 Vaccination: A 2024 Update.","authors":"Ikponmwosa J Ogieuhi, Fnu Suman, Nikita Kumari, Bai Manita, Dinkey Kumari, Joti Devi, Mohamed Abdalla, Eithar Shabbo, Utsav Patel, Iqra Samreen, Khalid H Mohamed, Zahoor Ahmed, Hira Nasir","doi":"10.7759/cureus.c339","DOIUrl":"https://doi.org/10.7759/cureus.c339","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.7759/cureus.59390.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"c339"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Adolescents' Diabetes Self-Management Regimens and Outcomes During the COVID-19 Pandemic: A Scoping Review.","authors":"Jason Nguyen, William Le, Roberta Brugger, Anjali Shah, Prasanna Karur, Macey Hedelund, John Joseph, Arshia Haj, Caroline Grillo, Nivene Hojeij, Jennifer Maizel","doi":"10.7759/cureus.c334","DOIUrl":"https://doi.org/10.7759/cureus.c334","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.7759/cureus.76343.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"c334"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: The Impact of High-Flow Nasal Cannula Therapy on Acute Respiratory Distress Syndrome Patients: A Systematic Review.","authors":"Ahmed M Abdelbaky, Wael G Elmasry, Ahmed H Awad, Sarrosh Khan, Maryam Jarrahi","doi":"10.7759/cureus.c336","DOIUrl":"https://doi.org/10.7759/cureus.c336","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.7759/cureus.41219.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"c336"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: A Systematic Review of the Comparative Efficacy of Lactobacillus Probiotics and Sodium Hypochlorite as Intracanal Irrigants Against Enterococcus faecalis.","authors":"Mrinalini Mrinalini, Alpa Gupta, Dax Abraham, Arun Kumar Duraisamy, Rajat Sharma","doi":"10.7759/cureus.c331","DOIUrl":"https://doi.org/10.7759/cureus.c331","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.7759/cureus.70926.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"c331"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Respiratory Illness in a Pediatric Patient With Chromosome 16p13.3 Microduplication Syndrome and Potential Seizure Risk.","authors":"Mikaela A Lee, Travis Smith, Katarzyna Madejczyk","doi":"10.7759/cureus.93668","DOIUrl":"10.7759/cureus.93668","url":null,"abstract":"<p><p>This case report outlines the management of a 16-month-old girl with chromosome 16p13.3 microduplication syndrome who presented with an acute respiratory illness. For signs and symptoms of croup, pneumonia, and otitis media, this patient required multiple administrations of racemic epinephrine, steroids, and albuterol to reduce inflammation and alleviate respiratory distress. Children with underlying medical conditions and genetic syndromes are likely to have a more complicated clinical course in the setting of acute illnesses. Thus, these patients require more intensive interventions and prolonged monitoring than the standard protocols. In this case, the treatment regimen was carefully tailored, with special attention to minimizing the risk of seizure activity. Furthermore, this case highlights the need for further exploration of the interaction between respiratory illnesses and underlying seizure disorders. The patient's presentation underscores the importance of neurological observation and a multidisciplinary approach to ensure the best possible outcome.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"e93668"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ignorance Is Not Bliss: A Systematic Review on the Impact of Ignoring UK Medical Students During Clinical Placements.","authors":"Hozafa Ali, Usama Ali","doi":"10.7759/cureus.93644","DOIUrl":"10.7759/cureus.93644","url":null,"abstract":"<p><strong>Introduction: </strong>Ignoring medical students on clinical placements is a form of mistreatment that is often overlooked. It is unclear how much research has been done on the topic. We performed the first United Kingdom (UK)-based systematic review on the topic of ignoring medical students. We employed a novel technique that incorporated the use of artificial intelligence (AI) to assist with the review.</p><p><strong>Methods: </strong>With the assistance of AI, Boolean search terms were generated to search through five databases in July 2025. Studies that described UK medical students being ignored were included in the final analysis. Inductive thematic analysis was performed to identify common themes between the studies. The Critical Appraisal Skills Programme (CASP) checklist for qualitative studies and the Mixed Methods Appraisal Tool (MMAT) for mixed-methods studies were utilized to assess study quality.</p><p><strong>Results: </strong>Six studies met the criteria to be included in the final analysis. Four common themes were identified when it came to ignoring medical students: exclusion from learning opportunities, emotional and professional invisibility, reporting barriers, and conflicting priorities between medical students and staff. Most of the CASP and MMAT points were met for the included studies, although studies had a small sample size, were often single-center studies, and had a skew toward students in the Midlands.</p><p><strong>Discussion: </strong>This novel AI-assisted systematic review provided vital information on how and why medical students are ignored in the UK. We propose that a vicious cycle exists when it comes to ignoring medical students. Specifically, students feel ignored, which leads to demotivation, ultimately resulting in disengagement. This leads to staff feeling as though students are uninterested, resulting in further ignoring of medical students. There is limited literature on the prevalence of ignoring medical students, and this is something that needs to be explored in the future.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"e93644"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Evolving Patterns of Etiological Profiles and Susceptibility Trends of Healthcare-Associated Infections Since Inception: A Meta-Analysis.","authors":"Purvi S Khristi, Remya P A, Jeswin Chandrasekhar, Ami C Patel","doi":"10.7759/cureus.c341","DOIUrl":"https://doi.org/10.7759/cureus.c341","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.7759/cureus.92260.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 10","pages":"c341"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}