Cureus最新文献

{"title":"Awareness of Peri-Implantitis Among General Dental Practitioners in Southern Saudi Arabia: A Cross-Sectional Study.","authors":"Sultan Alanazi","doi":"10.7759/cureus.77923","DOIUrl":"10.7759/cureus.77923","url":null,"abstract":"<p><strong>Aim and background: </strong>The success of dental implants is contingent upon various biological conditions, and any lapse in meeting these criteria can lead to complications such as peri-implantitis or implant failure. The objective of this research is to evaluate the level of understanding regarding peri-implant among general dentists practicing in Saudi Arabia.</p><p><strong>Materials and methods: </strong>A quantitative approach was employed, utilizing an online questionnaire distributed to general dental practitioners (GDPs) in Saudi Arabia. The level of significance was predetermined at a p-value less than 0.05, and chi-square tests were performed utilizing IBM SPSS Statistics for Windows, Version 20 (Released 2011; IBM Corp., Armonk, New York, United States). For collected data, descriptive analysis was also applied.</p><p><strong>Results: </strong>In general, just a few numbers of participants demonstrated adequate knowledge concerning peri-implantitis. Approximately 13.5% of respondents had undergone training in dental implants and engaged in probing around implants. Smoking and uncontrolled diabetes were identified as significant contributors to peri-implantitis by 18% and 12% of participants, respectively.</p><p><strong>Conclusion: </strong>Noteworthy concerns arose as 18.7% of practitioners did not conduct probing around implants. No statistically significant differences were observed based on gender, experience, or training level among the participants. This underscores the importance of addressing these lapses through targeted education and training programs to optimize overall patient care.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"e77923"},"PeriodicalIF":1.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143049305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcoidosis as an Uncommon Cause of Chest Pain: A Case Report.","authors":"Elisabete Ribeiro, Letícia Marques Leite, Isabel Bessa, João Pacheco, Filipa Gonçalves","doi":"10.7759/cureus.77913","DOIUrl":"10.7759/cureus.77913","url":null,"abstract":"<p><p>Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Despite primarily affecting the lung, sarcoidosis can affect any organ, resulting in various clinical manifestations. We present a case of a 56-year-old man who developed thoracic pain over several months along with skin lesions. The chest CT revealed multiple mediastinal lymphadenopathies. The patient underwent an endobronchial ultrasound, and a lymph node biopsy was performed. The histological results showed lymphoid cells and small epithelioid granulomas, while bronchoalveolar lavage revealed lymphocytosis, with a significantly elevated CD4+/CD8+ ratio. Based on the results, a diagnosis of sarcoidosis was presumed. The study was concluded with cardiac MRI due to complaints of chest pain, which also confirmed cardiac involvement. The patient was successfully treated with corticosteroids, exhibiting significant improvements and recovering completely during the follow-up period. Despite cardiac involvement in sarcoidosis being rare, we present this case to emphasize the challenges in diagnosis, requiring high clinical suspicion and the use of complementary imaging methods, such as cardiac magnetic resonance. We also emphasize the importance of early initiation of corticosteroid therapy to prevent major complications and promote recovery.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"e77913"},"PeriodicalIF":1.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143049367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction: Blood Parameter Profiles and Their Clinical Implications in Hypertensive Patients: A Retrospective Chart Review.","authors":"Ahmed S Al Zomia, Zia Sabah, Mosab Deajim, Abdullah H Alamri, Ghufran B Asiri, Lama A Lahiq, Wajd Alhadi, Nasser A Alwaqdi","doi":"10.7759/cureus.r164","DOIUrl":"https://doi.org/10.7759/cureus.r164","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.7759/cureus.43691.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"r164"},"PeriodicalIF":1.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143049362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analgesic Efficacy of Gabapentin in Patients Undergoing Carpal Tunnel Release Surgery: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.","authors":"Muteb N Alotaibi, Ohood Y Alasmari, Omar E Elshaer, Ibrahim S Allehaimeed, Hajar A Alharbi, Amal A Alsubaiei, Abdullah M Alharran, Abdulmuhsen Alqallaf, Mohammed Alshammari, Abdullah Alhuwailah, Ahmed F AlFaleh","doi":"10.7759/cureus.77808","DOIUrl":"10.7759/cureus.77808","url":null,"abstract":"<p><p>Carpal tunnel syndrome (CTS) results from median nerve compression and may lead to significant pain. Surgical management through release is the gold standard approach for severe CTS patients. Gabapentin is used as an analgesic drug, but data on its postoperative effects on pain assessment and safety measures are unclear. We aimed to assess the clinical effectiveness of gabapentin in patients undergoing CTS release surgery. We searched PubMed, Scopus, Web of Science (WOS), and the Cochrane Library for randomized controlled trials (RCTs) addressing the effectiveness of gabapentin in patients with CTS release until September 2024. The primary outcome was the assessment of postoperative pain at one, six, 12, and 24 hours by a visual analog scale (VAS). Other specific outcomes were adverse events. Data were pooled as effect sizes (mean difference (MD) or odds ratio (OR)) with their 95% confidence interval (CI) in a random-effects model using Stata/MP 18. Three RCTs comprising 205 patients were included in the pooled meta-analysis. Gabapentin significantly reduced postoperative pain at six, 12, and 24 hours compared to placebo (MD = -0.6, 95% CI: -0.63 to 0.57, p < 0.001; MD = -2.14, 95% CI: -2.18 to -2.1, p < 0.001; and MD = -1.41, 95% CI: -1.82 to -0.99, p < 0.001, respectively). On the other hand, no significant differences were observed regarding other studied outcomes (i.e., safety) between the two groups. This pooled meta-analysis of 205 patients revealed that gabapentin was associated with reduced pain postoperatively at 6, 12, and 24 hours with comparable rates of adverse events compared to placebo. Further RCTs are warranted to validate the current findings.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"e77808"},"PeriodicalIF":1.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction: A Rare Surgical Case of Isolated Double-Chambered Right Ventricle Without Cardiac Malformations in an Older Female Patient.","authors":"Yuki Hayashi, Shunji Osaka, Satoshi Unosawa, Masashi Tanaka","doi":"10.7759/cureus.r162","DOIUrl":"https://doi.org/10.7759/cureus.r162","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.7759/cureus.74051.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"r162"},"PeriodicalIF":1.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Effect of Periodontitis on Trabecular Bone Structure by Fractal Analysis.","authors":"Emrullah B Dosdogru, Melis Ziyaettin, Ahmet F Ertürk","doi":"10.7759/cureus.77833","DOIUrl":"10.7759/cureus.77833","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the trabecular microarchitecture in the interdental region of panoramic radiographs from periodontally healthy individuals and those with stage III/IV periodontitis using fractal analysis (FA), while also assessing the relationship between clinical periodontal parameters and FA outcomes.</p><p><strong>Study design: </strong>Clinical and radiographic records of 20 periodontally healthy individuals and 19 individuals with stage III/IV periodontitis were included. Clinical measurements including the plaque score, bleeding on probing, probing pocket depth, and clinical attachment level were recorded. A region of interest was selected on panoramic radiographs from the mesial aspect of the mandibular first molar and the distal aspect of the second premolar. The fractal dimension (FD) values for this region were calculated using the box-counting method. The statistical significance of the difference was evaluated at P<0.05.</p><p><strong>Results: </strong>There was no significant statistical difference in sex between the groups (p > 0.05). Conversely, individuals in the periodontitis group had a significantly higher mean age compared to those in the healthy group (p < 0.01). Clinical measurements were significantly higher in the periodontitis group (p < 0.01). However, no significant differences in FD values were observed between the groups (p > 0.05). In the healthy group, moderate negative correlations were found between FD and clinical parameters (with all p < 0.05), while no such correlations were identified in the periodontitis group (with all p > 0.05).  Conclusion: FA demonstrates potential as a complementary diagnostic tool when used alongside clinical periodontal measurements. However, its effectiveness as a standalone method for reliably distinguishing between healthy individuals and those with periodontitis remains limited. Advanced radiographic analysis can further enhance the identification of anatomical details, thereby improving the accuracy of periodontal evaluations and diagnostics.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"e77833"},"PeriodicalIF":1.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction: Iptacopan Efficacy and Safety to Treat Paroxysmal Nocturnal Hemoglobinuria (PNH): A Systematic Review and Meta-Analysis.","authors":"Ibrahim M Dighriri, Reham M Al-Qahtani, Amal O Almutairi, Rahaf N Alhashbari, Hanin A Kanbeja, Salman A AlOjaimi, Mona A Aljuaid, Abdullah A Albaradi, Sahar T Almanjumi, Samah A Alqurashi, Maryam S Majrashi, Hatoon M Alansari, Ghayah A Jabbari, Abdulaziz S Alharbi, Amnah A Alnami","doi":"10.7759/cureus.r163","DOIUrl":"https://doi.org/10.7759/cureus.r163","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.7759/cureus.67830.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"r163"},"PeriodicalIF":1.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biologic Treatments for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP): A Comparative Review of Efficiency and Risks.","authors":"Mihai I Tănase, Mara Tanase, Marcel Cosgarea, Gheorghe Doinel Radeanu, Septimiu Sever Pop, Alma A Maniu","doi":"10.7759/cureus.77804","DOIUrl":"10.7759/cureus.77804","url":null,"abstract":"<p><p>Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition of the nasal passages and sinuses, often characterized by nasal congestion, loss of smell, facial pressure, and nasal discharge. Conventional treatments, such as corticosteroids and endoscopic sinus surgery (ESS), often provide only temporary relief, with frequent recurrence of symptoms. For patients with severe, refractory CRSwNP, biologic therapies have emerged as a promising treatment option. This review evaluates the efficacy and safety of biologic treatments for CRSwNP, including dupilumab, mepolizumab, and omalizumab. We analyze clinical trial data, patient-reported outcomes, and the latest research on the use of biologics in CRSwNP management. Our findings confirm the efficacy of biologics in treating CRSwNP, showing consistent improvements in both clinical and patient-reported outcomes. The use of biologics resulted in a significant reduction in nasal polyp size, improved nasal congestion, and reduced the need for further surgery or systemic corticosteroids. Moreover, patients experienced an improved sense of smell and a better quality of life. This review also includes a comparative analysis of the three biologics, highlighting their efficiency and potential risks. The findings suggest that dupilumab may be the most effective biologic therapy for CRSwNP, showing superior efficacy compared to mepolizumab and omalizumab in reducing nasal polyp size and improving nasal congestion. The article provides valuable insights for healthcare providers and patients considering biologic therapy for CRSwNP, emphasizing the importance of personalized treatment decisions based on individual patient factors, including disease severity, comorbidities, and preferences.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"e77804"},"PeriodicalIF":1.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attitudes and Awareness Regarding Health Information Sought on Social Media by the Saudi Population: A Cross-Sectional Study.","authors":"Aroob Alhuthail, Bodour Aloraini, Ilal Alhuthail, Sara M Alrashidi, Renad M Alotibi","doi":"10.7759/cureus.77759","DOIUrl":"10.7759/cureus.77759","url":null,"abstract":"<p><p>Background Social media (SM) platforms are commonly used in Saudi Arabia, even for health information. SM platforms allow users to have conversations, share information, and create web content. Given the growing dependence on social media for health-related concerns, it is critical to understand how Saudis use these platforms to get health information. This study aimed to determine the Saudi population's attitude and awareness regarding health information sought on SM. Subject and methods This cross-sectional study was conducted among adults in Riyadh, Kingdom of Saudi Arabia, from September to October 2024. A self-administered questionnaire was distributed randomly in the Medical City King Saud University family medicine clinic. The questionnaire includes socio-demographic data (i.e., age, gender, marital status, etc.), the most commonly used type of SM, and various questions to assess the knowledge and influence of SM on health information.  Results Among the 330 participants, 117 (63%) were female respondents, and 126 (38.2%) were between 31 and 40 years old. WhatsApp was the most prominent type of SM used at 192 (58.2%). Disease or medical problems were the most notable health information being seen online at 172 (52.1%), and \"to be informed\" was the most common reason for seeking health information online at 237 (72.4%). The perception of unemployed female respondents that health information obtained from SM is reliable was significantly higher than that of unemployed male respondents (p<0.05). Surprisingly, male participants usually do believe SM can enhance awareness (p = 0.015). Conclusion The findings of this study suggest that SM influences the behavior of the adult population seeking health information in Saudi Arabia. Female participants tended to believe that the health information obtained from SM was credible. To be more informed was the primary reason for seeking health information online. There is a need to educate patients visiting family medicine clinics about the reliability of health information obtained online.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"e77759"},"PeriodicalIF":1.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saving a Mandibular Molar With Distal Root Resorption: A Case Report.","authors":"Abdulaziz A AlHelal, Faisal A AlHelal, Mohammed F Alem, Abdullah M Albaiz, Mohammed Y AlGammlas, Khalid W AlRashed, Mohammed Alselmi","doi":"10.7759/cureus.77775","DOIUrl":"10.7759/cureus.77775","url":null,"abstract":"<p><p>In this case study, an all-ceramic (Emax) crown and a post and core restoration are used to successfully treat external inflammatory root resorption (EIRR) in a mandibular molar. A 21-year-old male patient was diagnosed with EIRR and hypercementosis after presenting with pain and significant damage to his lower right first molar. The patient chose a post and core restoration over extraction and implant placement due to budgetary constraints. Endodontic retreatment, fiber post cementation, core buildup, and Emax crown placement were all part of the treatment. At the one-year follow-up, the patient had a healed periapical region, healthy gingiva, and sound tooth structure. In managing EIRR cases, this case study emphasizes the importance of meticulous treatment planning and execution, focusing on selecting the best course of action for the long-term stability and health of the affected tooth. Both the patient's overall dental health and the expertly crafted restoration contributed to the favorable outcome.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 1","pages":"e77775"},"PeriodicalIF":1.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11749096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}