Clinical ophthalmology (Auckland, N.Z.)最新文献

{"title":"Evaluation of a Modified Single-Stage Continuous Curvilinear Capsulorhexis Technique Using 18-Gauge Needle Decompression in Intumescent Cataracts.","authors":"Trung Kien Hoang, Huynh Phuc Nguyen, Van Nam Phan","doi":"10.2147/OPTH.S541643","DOIUrl":"10.2147/OPTH.S541643","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the safety and efficacy of a modified anterior capsulorhexis technique using an 18-gauge needle puncture at the peripheral one-third of the anterior capsule to control intralenticular pressure and achieve single-stage continuous curvilinear capsulorhexis (CCC) in intumescent cataract surgery.</p><p><strong>Methods: </strong>This prospective, cross-sectional descriptive study included patients with intumescent cataracts indicated for surgery at Saigon Vinh Eye Hospital from August 2024 to March 2025. Before CCC, all patients underwent an 18-gauge needle puncture at the peripheral one-third of the anterior capsule near the main incision.</p><p><strong>Results: </strong>A total of 99 eyes from 99 patients were included in the study. The mean axial length was 23.12 ± 0.55 mm, anterior chamber depth 2.62 ± 0.43 mm, and lens thickness 4.91 ± 0.72 mm. In 65 patients (65.7%), the milky liquefied cortex escaped into the anterior chamber after the needle puncture. Single-stage CCC was successfully performed in 98 of 99 cases (98.9%) with a mean capsulorhexis diameter of 5.5 ± 0.3 mm. All surgeries were performed using standard phacoemulsification and in-the-bag IOL implantation (100%). Three months post-operatively, all patients had well-centered IOLs with a best-corrected visual acuity (BCVA) ≥ 4/10.</p><p><strong>Conclusion: </strong>An 18-gauge needle puncture at the peripheral one-third of the anterior capsule offers effective decompression, improves safety, and facilitates CCC in patients with intumescent cataracts. This technique is simple, feasible, and highly applicable in clinical practice.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3339-3346"},"PeriodicalIF":0.0,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Combined Phacoemulsification and Hydrus Microstent in Open-Angle Glaucoma Versus Combined-Mechanism/Primary Angle Closure Glaucoma.","authors":"Kelly Nguyen, Sunee Chansangpetch, Minh-Khanh Vinh, Alan Quang Huy Tran, Sunita Radhakrishnan, Ngoc Nguyen, Andrew G Iwach, Shan Lin","doi":"10.2147/OPTH.S538439","DOIUrl":"10.2147/OPTH.S538439","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the pressure-lowering efficacy of cataract surgery combined with Hydrus microstent in mainly Asian eyes with combined-mechanism glaucoma (CMG) or primary angle closure glaucoma (PACG) versus open-angle glaucoma (OAG).</p><p><strong>Patients and methods: </strong>Patients with CMG, PACG, or OAG who were treated with 1 or more glaucoma medications prior to surgery were included in the study. Medical charts were reviewed for patients with CMG, PACG, or OAG undergoing cataract-Hydrus surgery. Multilevel mixed-effects linear regression models were performed to determine the efficacy of combined surgery on intraocular pressure (IOP) and number of glaucoma medications. Mixed-effects logistic regression models were used to assess post-operative 1-year success rate (IOP ≤ 18 mmHg without glaucoma medication) and percentage of medication-free patients.</p><p><strong>Results: </strong>The post-operative IOP and medication use were compared in CMG/PACG (n = 49) and OAG (n = 29) eyes. At 1-year follow-up, IOP decreased in CMG/PACG (14.74 to 13.21 mmHg, p = 0.004) and was unchanged in OAG (14.48 to 14.84 mmHg, p = 0.56) (difference in absolute IOPs, p=0.02). IOP was significantly lower in CMG/PACG group compared to OAG group with a coefficient of -2.1 (95% CI - 3.9 to -0.4, p=0.02). The success rates were similar (82%, CMG/PACG; 79%, OAG, p=0.80). Both groups showed significant reductions in medications (CMG/PACG, 2.33 to 0.20, p<0.001; OAG, 2.37 to 0.38, p<0.001; between groups, p=0.20). 83% of patients achieved medication-free status (OAG, 83%; CMG/PACG, 84%, p=0.92). Regarding surgical complications, there was no significant difference between OAG and CMG/PACG groups for postoperative hyphema (p=0.64) and IOP spike (p=0.29).</p><p><strong>Conclusion: </strong>In this retrospective study, the IOP-lowering efficacy of combined cataract-Hydrus surgery in CMG/PACG patients was similar or greater than in OAG patients.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3347-3356"},"PeriodicalIF":0.0,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic Characteristics, Contributing Risk Factors, and Prognosis of <i>Acanthamoeba</i> Keratitis in Eastern China: An in vivo Confocal Microscopy-Based Fifteen-Year Study.","authors":"Chuwei Lu, Jiajia Wang, Jiaxu Hong, Jianjiang Xu, Xujiao Zhou, Lijia Tian, Qihua Le","doi":"10.2147/OPTH.S545322","DOIUrl":"10.2147/OPTH.S545322","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the demographic characteristics, contributing risk factors, and prognostic outcomes of <i>Acanthamoeba</i> keratitis (AK) in Eastern China in the recent 15 years using in vivo confocal microscopy (IVCM).</p><p><strong>Patients and methods: </strong>This single-center, retrospective study included 145 patients (147 eyes) diagnosed with AK based on IVCM findings at the Eye & ENT Hospital of Fudan University from April 2009 to September 2024. Demographic information, clinical features at presentation, contributing risk factors (if identified), treatment strategies, and final visual outcomes were retrieved in the medical records and analyzed using descriptive statistics.</p><p><strong>Results: </strong>The median age of patients was 51 years old, with 98.6% of infections being unilateral. Corneal trauma (62.1%) was the leading risk factor overall, whereas contact lens wear was the independent risk factor among children and adolescents. The most common clinical features at presentation were stromal infiltrate (60.6%) and deep stromal ulcers (36.5%). Anti-AK therapy was mainly composed of polyhexamethylene biguanide (PHMB), chlorhexidine, propamidine isethionate (Brolene) and metronidazole. Surgical interventions were required in 24 eyes, with evisceration/enucleation identified as an independent predictor of poor visual prognosis.</p><p><strong>Conclusion: </strong>This study provides valuable epidemiological insights into AK in Eastern China, underscoring the need for improved prevention, early diagnosis, and evidence-based treatment protocols to guide clinical management.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3295-3305"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12433226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of a Modified Risk Stratification Score in Cataract Surgery at a Swiss Public Hospital.","authors":"Klemens Paul Kaiser, Ferhat Turgut, Sophie-Christin Kornelia Ernst, Gabor Mark Somfai, Jay Rodney Toby Zoellin, Amr Saad, Noah Davolio, Ute Hornberger, Henning Nilius, Julie Susan Heussen, Matthias Dieter Becker, Florian M Heussen","doi":"10.2147/OPTH.S544354","DOIUrl":"10.2147/OPTH.S544354","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluates the impact of a modified risk stratification system on intraoperative complication rates in cataract surgeries conducted at a Swiss Public Hospital.</p><p><strong>Methods: </strong>In this retrospective study cataract surgeries were analyzed before and after implementation of the Triemli Cataract Score (TCS) at a public referral hospital. The TCS was utilized to classify patients preoperatively based on their risk profile, categorizing cases into three levels of complexity: \"routine\", \"complex\", and \"highly complex\". The primary endpoint is the frequency of intraoperative complications pre-/post-TCS implementation, as well as alignment with the designated risk groups.</p><p><strong>Results: </strong>A total of 1776 eyes were included in the study, with 704 eyes (39.6%) assessed prior to and 1072 (60.4%) post-TCS implementation. Overall, intraoperative complications were observed in 146 surgeries (8.2%), with a higher incidence observed before (9.5%) compared to post-TCS (7.4%; p=0.054). Post-TCS, 625 (63.2%) were classified as \"routine\", 250 eyes (25.3%) as \"complex\", and 113 eyes (11.4%) as \"highly complex\", based on their risk factors. The intraoperative complication rate varied significantly among these groups (p=0.014): the lowest rate was seen in the routine group (5.6%), followed by the highly complex group (8.8%), and the highest in the complex group (11.2%).</p><p><strong>Discussion: </strong>Implementing a risk stratification system for cataract surgery enables efficient and consistent preoperative categorization of patients into defined risk groups. This approach has the potential to reduce intraoperative complications, improve the comparability of study outcomes, streamline the classification process for surgeons, and establish structured checkpoints for training ophthalmic surgeons.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3307-3316"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12433236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prioritising the Burden of Geographic Atrophy and Treatment Expectations: A Modified Nominal Group Technique Study with International Patient-Led Organisations.","authors":"Nabin Paudel, Ellen M Moran, Sinead Stafford, Kelly McVicker, Petia Stratieva, Avril Daly","doi":"10.2147/OPTH.S525046","DOIUrl":"10.2147/OPTH.S525046","url":null,"abstract":"<p><strong>Aim: </strong>Geographic atrophy (GA), an advanced form of dry AMD, impacts over 5 million people globally and leads to progressive, irreversible vision loss. Current approaches to GA treatment aim to prevent and delay disease progression and preserve remaining vision. However, there is a debate on what constitutes a meaningful treatment outcome for patients. The aim of this study was to prioritise challenges associated with GA and desired treatment expectations from therapies using a modified Nominal Group Technique (NGT).</p><p><strong>Methods and analysis: </strong>The study employed a modified nominal group technique (NGT), a widely used, validated, structured, facilitated group meeting to generate consensus. Representatives from patient-driven international research funding and support organizations were invited to participate. Two questions, one asking the impact of GA on patients and caregivers and another asking the treatment expectations of GA therapies were posed during the NGT session. Standard NGT methods were followed to generate top 10 challenges of living with GA and treatment expectation as perceived by the participants.</p><p><strong>Results: </strong>The group ranked loss of independence (score - 32/50), difficulty recognizing faces (score - 28/50), impairment in daily living activities (scores - 11 to 22/50), and mental health issues (scores - 19/50 - anxiety, 21/50 - depression) as the most significant challenges faced by people living with GA. The group also prioritised stability of vision (score - 47/50), ability to recognise faces (score - 27/50) and one time therapy (score - 19/50) as their top expectations from GA treatments.</p><p><strong>Conclusion: </strong>This study successfully used the NGT to prioritise challenges associated with GA and treatment expectation of GA therapies. The consensus results imply that meaningful progress in GA care will come from therapies that realistically aim to slow further vision loss, are convenient to use, and are delivered alongside psychosocial and low-vision support.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3317-3329"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12433235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subjective Grading and Objective Assessment After Switching to a Daily Disposable Silicone Hydrogel Contact Lens.","authors":"Ya-Yu Chen, Ren-Yu Yang, Han-Yin Sun","doi":"10.2147/OPTH.S538886","DOIUrl":"10.2147/OPTH.S538886","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate both subjective grading and objective assessments associated with switching from habitual silicone hydrogel daily disposable contact lenses to verofilcon A lenses (study lenses) among young Asian individuals, and to investigate the relationship between these subjective and objective measures.</p><p><strong>Patients and methods: </strong>58 participants wore study lenses for 8-10 hours daily for a week. Subjective assessments, including comfort, visual quality, and eye dryness, were conducted using a numerical rating scale (0-100) on the first and seventh day. Noninvasive tear breakup time (NITBUT), bulbar conjunctival redness (BR), tear meniscus height (TMH), and meibography were measured with the Keratograph M5 at baseline, the first and the seventh day.</p><p><strong>Results: </strong>After the seventh day, subjective ratings showed increased comfort and decreased visual quality and dryness. Comfort and visual quality scores on the first and seventh days were above 85 points, with no significant differences. The average NITBUT significantly improved 15 minutes and 8 hours post-lens application compared to baseline measures (<i>P</i> = 0.019). Tear meniscus height was highest at baseline, with a marginal decrease observed following both 15 minutes and 8 hours of study lenses wear (<i>P</i> < 0.001). The most pronounced bulbar conjunctival redness was noted at baseline, decreasing significantly after switching to study lenses (<i>P</i> = 0.002). Notably, NITBUT was found to be significantly positively correlated with comfort (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The switch to daily disposable study lenses resulted in maintained comfort and improved tear film stability in the young Asian population. A significant positive correlation was observed between NITBUT and subjective measures of comfort.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3273-3281"},"PeriodicalIF":0.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12422125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Monofocal IOLs Improve Patient Satisfaction in Phaco-Vitrectomy for ERM.","authors":"Junya Ota, Masaaki Matsunaga, Fuminori Haga, Ayana Suzumura, Kazuhisa Yamada, Hideyuki Shimizu, Shu Kachi, Ichiro Ota, Goichiro Miyake, Kumiko Mokuno, Daiki Inooka, Emi Iwata, Tomohiko Akahori, Koji M Nishiguchi, Hiroki Kaneko","doi":"10.2147/OPTH.S541269","DOIUrl":"10.2147/OPTH.S541269","url":null,"abstract":"<p><strong>Purpose: </strong>Tecnis Eyhance (DIB00V) is a type of monofocal intraocular lens (IOL) categorized as \"IOL-plus\", a new concept developed to improve not only distance but also intermediate vision. However, its negative effect, eg difficulty in macular surgery that is occasionally seen with the multifocal IOL, has not been ruled out in combined surgery for epiretinal membrane (ERM) and cataracts. This study aimed to compare DIB00V with a conventional monofocal IOL (DCB00V) in terms of visual acuity and patient-reported outcomes of combined surgery for epiretinal membrane (ERM) and cataracts.</p><p><strong>Methods: </strong>This was a multicenter, prospective, nonrandomized, observational study conducted in Japan. Patients scheduled for combined cataract and pars plana vitrectomy (PPV) for cataract and ERM were enrolled. IOL was selected according to the rules originally applied in each facility. Best-corrected distance visual acuity (BCDVA) and distance-corrected intermediate visual acuity (DCIVA) at 3-month visits postoperatively, surgical parameters, and Japanese-modified Catquest-9SF Questionnaire scores were compared between the two IOL groups.</p><p><strong>Results: </strong>Sixty-two eyes implanted with DCB00V (Tecnis-1) and 79 eyes implanted with DIB00V (Eyhance) were analyzed. There was no significant difference in BCDVA with Eyhance (0.09 in logMAR) and Tecnis-1 (0.05 in logMAR, <i>p</i> = 0.174), and DCIVA with Eyhance (0.35 in logMAR) and Tecnis-1 (0.39 in logMAR, <i>p</i> = 0.200). Rasch analysis of the Japanese-modified Catquest-9SF Questionnaire revealed that Eyhance scored higher in patients' general satisfaction (<i>p</i> = 0.0269). Subgroup analysis revealed a better postoperative distance-corrected intermediate visual acuity in patients with a certain degree of preoperative myopia (spherical error < -1.5 diopter).</p><p><strong>Conclusion: </strong>Eyhance provided comparable postoperative visual acuity to the conventional monofocal IOL in combined surgery for cataract and ERM, and surgical parameters are not different in the two types of IOL. Furthermore, Eyhance improved postoperative satisfaction in the overall population and significantly improved intermediate visual acuity in the preoperatively myopic population.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3283-3293"},"PeriodicalIF":0.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12423440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Short-Term Results of Supraciliary Ab-Interno MINIject^® Implantation Following Failed Filtering Glaucoma Surgery in Primary Open-Angle Glaucoma.","authors":"Jan Niklas Lüke, Vincent Lüke, Thomas Dietlein, Johanna Wiedemann, Alexandra Lappas","doi":"10.2147/OPTH.S534745","DOIUrl":"10.2147/OPTH.S534745","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the efficacy of MINIject^® (suprachoroidal stent) in lowering intraocular pressure (IOP) in eyes following failed filtering glaucoma surgery.</p><p><strong>Methods: </strong>In this single-center retrospective study, 18 patients who had undergone suprachoroidal stent implantation after failed filtering surgery were analyzed. Follow-up was at least 12 months, and surgical success was measured by 12-month postoperative intraocular pressure (IOP), glaucoma medication, and revision surgery (criteria A: IOP < 21 mmHg, IOP reduction >20%, no revision surgery; criteria B: IOP < 18 mmHg, IOP reduction >20%, no revision surgery; criteria C: IOP ≤ 15 mmHg, IOP reduction ≥40%, no repeat surgery).</p><p><strong>Results: </strong>After a follow-up period of 12 months, the mean IOP decreased from 27.11±5.65 mmHg to 15.94±9.56 mmHg (p<0.01). The median 12-month postoperative IOP was 14.0 mmHg (IQR: 10.0-20.0 mmHg). The probability of surgical success was 66.66% for criteria A and B and 50% for criteria C. The identical success rates for criteria A and B were due to overlapping responder groups in this limited sample. Topical medication was significantly reduced from 4.06±1.08 to 2.13±1.36 (p<0.0001).</p><p><strong>Conclusion: </strong>Supraciliary stent implantation provided an effective and safe treatment option for advanced glaucoma following failed filtering surgery and demonstrated significant intraocular pressure reduction. However, the small sample size limits the generalizability of these findings.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3227-3235"},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three Year Results from the United States FDA Prospective Multicenter Clinical Study of the EVO/EVO+ Implantable Collamer Lens.","authors":"Gregory Parkhurst, Jason P Brinton, Alan Faulkner, Majid Moshirfar, Lance J Kugler, Jason E Stahl, Zachary Zavodni, Vance M Thompson, Francis W Price, William F Wiley, Michael Aronsky, Jeffrey D Whitman, Jonathan D Solomon, Scott A Perkins, Mark Packer, Joanne Egamino","doi":"10.2147/OPTH.S537739","DOIUrl":"10.2147/OPTH.S537739","url":null,"abstract":"<p><strong>Background: </strong>Continued safety and effectiveness of collamer EVO ICL posterior chamber phakic lenses with a central port design for the correction of myopia with or without astigmatism.</p><p><strong>Patients and methods: </strong>Subjects aged 21 to 45 years with moderate to high myopia and astigmatism up to 4.00 D underwent EVO or EVO+ Sphere or Toric ICL (collectively referred to as EVO ICL) surgery. Uncorrected and corrected distance visual acuity (UDVA, CDVA), manifest refraction, intraocular pressure (IOP), endothelial cell density (ECD), and adverse events were assessed over 3 years.</p><p><strong>Results: </strong>This prospective multicenter study included 629 eyes (327 subjects), with a mean age of 35.6 ± 5.1 years. Mean spherical equivalent (SE) was -7.62 ± 2.75 D (range: -3.00 to -15.62 D) preoperatively, and -0.12 ± 0.30 D at 3 years with 90.7% of eyes within ± 0.50 D and 99.0% within ±1.00 D of target. Mean postoperative UDVA and CDVA were -0.053 ± 0.12 logMAR and -0.13 ± 0.08 logMAR, respectively. Additionally, 48.9% of eyes gained 1 or more lines of CDVA. Efficacy and safety indices were 1.07 and 1.25, respectively. Two eyes (0.32%) underwent lens exchange for high vault; neither of these demonstrated increased IOP. One eye (0.16%) developed an anterior subcapsular cataract (ASC) at 2 years. No eyes experienced pupillary block requiring peripheral iridotomy or iridectomy (PI), elevated IOP due to angle narrowing, or pigment dispersion. Mean ECD decreased by 3.0% from baseline at 1 year and by 6.7% at 3 years.</p><p><strong>Conclusion: </strong>This 3-year study confirmed the central port design of the EVO ICL functions effectively to allow physiologic flow of aqueous humor, thus eliminating the requirement for preoperative PI and reducing the incidence of ASC and pupillary block. EVO ICL lenses demonstrated accuracy and stability of refractive correction and achievement of high levels of UDVA.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3237-3248"},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitrectomy as a Prevention for Retinal Detachment in High-Risk Eyes.","authors":"Robert E Morris, Ferenc Kuhn, Mathew R Sapp, Harshvardhan Chawla","doi":"10.2147/OPTH.S530665","DOIUrl":"10.2147/OPTH.S530665","url":null,"abstract":"<p><p>Rhegmatogenous retinal detachment (retinal detachment, RD) is the most common cause of spontaneous vision loss in aging eyes that were seeing normally until the moment of its occurrence. Causative retinal breaks usually occur in the form of peripheral tears at the vitreous base, resulting from traction exerted by the aging vitreous as it detaches posteriorly. Peripheral encircling laser retinopexy increases retinal resistance to vitreous traction in high-risk eyes. To achieve maximal lifetime prophylaxis, we show that in selected high-risk cases the vitreous can thereafter be removed by advanced vitrectomy techniques, reducing vitreous traction itself.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3249-3253"},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}