Clinical ophthalmology (Auckland, N.Z.)最新文献

{"title":"Trends in Glaucoma Fellowship Surgical Experience.","authors":"Jack Creagmile, Natalie Chen, Philina Yee, Ken Lin, Austin Fox, Andrew Smith, Claire Kwan, Sameh Mosaed","doi":"10.2147/OPTH.S526259","DOIUrl":"10.2147/OPTH.S526259","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate trends in fellow exposure to trabeculectomy, tube shunt, and minimally invasive glaucoma surgery (MIGS) procedures during glaucoma fellowship training.</p><p><strong>Methods: </strong>We analyzed fellowship surgical logs from 2013 to 2024 from the Association of University Professors of Ophthalmology (AUPO) Fellowship Compliance Committee to determine the frequency of trabeculectomy, tube shunt, and MIGS procedures within glaucoma fellowship programs.</p><p><strong>Results: </strong>Our analysis revealed a 55.9% decrease with significant correlative decline (r = -0.89, p = 0.0002) over the 11-year study period in total trabeculectomy exposure (primary and assistant surgeon), while total tube shunt surgeries underwent a modest 7.3% decrease with significant correlative decline (r = -0.80, p = 0.003) over the 11-year study period, and MIGS procedures showed a marked 128.6% increase with significant correlative increase (r = +0.72, p = 0.02) from 2016 to 2024.</p><p><strong>Conclusion: </strong>The declining exposure to trabeculectomy surgery, both as primary and assistant surgeon raises concerns about glaucoma fellowship graduate proficiency with this fundamental procedure. This may limit access to qualified care for specific glaucoma populations that may benefit most from this intervention, and for the continued care of patients that have previously undergone trabeculectomy surgery. These findings highlight the need to maintain proficiency in trabeculectomy to ensure optimal care for diverse glaucoma patient populations.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2719-2727"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical and Functional Outcomes of Anti-VEGF Therapy in Pachychoroid Neovasculopathy.","authors":"Vasilena Sitnilska, Johannes Maximillian Pohl, Yuhe Tang, Katrin Löw, Jeany Q Lammert, Tim U Krohne, Lebriz Altay","doi":"10.2147/OPTH.S529840","DOIUrl":"10.2147/OPTH.S529840","url":null,"abstract":"<p><strong>Background: </strong>Evaluation of real-life effectiveness of anti-VEGF therapy in patients diagnosed with pachychoroid neovasculopathy (PNV).</p><p><strong>Methods: </strong>This retrospective analysis included central serous chorioretinopathy (CSC) patients who developed PNV and underwent anti-VEGF treatment. Individuals with concomitant retinal diseases were excluded. Key measures included best-corrected visual acuity (BCVA), spectral domain optical coherence tomography (SD-OCT) features (intra-/subretinal fluid, central retinal thickness (CRT), and choroidal thickness (CT)), and potential risk factors such as age, sex, and corticosteroid intake, baseline neovascularization area in fluorescein angiography and in OCT-angiography, and time from PNV diagnosis to treatment initiation.</p><p><strong>Results: </strong>The study included 40 eyes of 40 patients (24 males, 16 females), with a mean follow-up period of 38.23±19.73 months and a mean number of anti-VEGF injections of 27.47±16.73. BCVA, CRT and CT improved significantly at the final visit compared to baseline (BCVA p=0.019, CRT p<0.001, CT p<0.001). 85% of eyes achieved a \"completely dry\" status on SD-OCT after a mean of 10.94±11.22 months and a mean of 8.88±9.17 injections. However, 82.4% of these eyes had a recurrence after a mean 3.32±4.82 months. There was no significant association of the evaluated risk factors with the treatment response. At the end of the observation period, there was no significant difference in BCVA between the \"completely dry\" group and the non-responders (p=0.765).</p><p><strong>Conclusion: </strong>A majority of PNV patients exhibit anatomical and functional improvement following anti-VEGF therapy. However, the high rate of recurrences suggests a need for long-term treatment.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2699-2707"},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Intraoperative Aberrometry-Based Prediction of Postoperative Refraction and Astigmatism After Novel Toric Intraocular Lens Implantation.","authors":"Atsushi Otani","doi":"10.2147/OPTH.S534932","DOIUrl":"10.2147/OPTH.S534932","url":null,"abstract":"<p><strong>Purpose: </strong>This study prospectively assessed the refractive and astigmatism prediction accuracy of intraoperative aberrometry, Optiwave Refractive Analysis (ORA), in eyes implanted with Clareon toric intraocular lenses (IOLs).</p><p><strong>Patients and methods: </strong>Patients with age-related cataracts who underwent phacoemulsification and toric IOL implantation using ORA were prospectively included in this single-center study. The absolute refractive prediction error (RPE) and rate of RPE for ORA, Sanders-Retzlaff-Kraft/Theoretical (SRK/T), and Barrett Universal II were evaluated 3 months after surgery. Uncorrected visual acuity (UCVA), residual astigmatism, refractive astigmatism prediction error, and the difference between the preoperatively planned axis and actual inserted axis recommended by ORA were assessed.</p><p><strong>Results: </strong>Eighty eyes (80 patients, mean age: 75.0 ± 8.8 years) were included in this study. Mean ± standard deviation (SD) of preoperative corneal astigmatism was 1.91 ± 1.03 D. The median absolute RPE values for ORA, SRK/T, and Barrett Universal II were 0.17, 0.14, and 0.14 D, respectively. At the 3-month follow-up after surgery, the mean ± SD of UCVA and residual astigmatism were 0.06 ± 0.16 logarithm of the minimum angle of resolution and 0.43 ± 0.48 D, respectively. The refractive astigmatism prediction errors were 0.11 D in the centroid for both ORA and the Barrett toric formula, at 67° and 63°, respectively. The mean absolute values were 0.38 D for ORA and 0.41 D for the Barrett toric formula. The median absolute value of the axis difference between the planned and actual inserted axes based on ORA was 4.00°.</p><p><strong>Conclusion: </strong>The accuracy of ORA in the prediction of spherical refraction and astigmatism was comparable to that of the preoperative IOL calculation formula in eyes with Clareon toric IOLs. ORA is a useful tool for determining IOL power and improving preoperative corneal astigmatism.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2681-2689"},"PeriodicalIF":0.0,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12356219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evolving Role of Ultrasound in Diagnosis and Treatment of Eye Emergencies: A Narrative Review.","authors":"Ahmed Saad Al Zomia, Asma Sulaiman Hassan Alshahrani, Abdullrahman Saeed A Alshahrani, Mohammed Nasser M Alahmari, Saleh Saeed Al Jathnan Al Qahtani, Ahmad Mohammad Althawaby, Abdulrahman Ahmed Mohammed Asiri, Mazen Abdullah Al Qahtani, Suleiman Mohammed A Alburidy, Ahad Essa Mohammed Asiri","doi":"10.2147/OPTH.S539320","DOIUrl":"10.2147/OPTH.S539320","url":null,"abstract":"<p><p>In clinical practice, ocular emergencies provide a considerable challenge, typically necessitating prompt and precise diagnosis to avoid irreversible vision impairment. The accessibility, speed, and diagnostic capability of conventional imaging modalities are limited in specific situations, notwithstanding their effectiveness. In the management of ocular emergencies, ultrasound has become a revolutionary technology, providing real-time, non-invasive, and very precise diagnostic and therapeutic possibilities. The present narrative review examines the dynamic nature of ultrasonography in the management of ocular emergencies. It assesses the diagnostic precision, clinical use, therapeutic effectiveness, prospects, and the necessary training for healthcare practitioners. Through the synthesis of existing empirical data, this study emphasizes the capacity of ultrasound to improve patient outcomes and optimize emergency ophthalmic care.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2691-2698"},"PeriodicalIF":0.0,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12356204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Incidence of Posterior Ocular Astigmatism in a Refractive Surgery Population as Determined by the Direct Reduction of Topography Measured Astigmatism.","authors":"Manoj Motwani, Lourdes Haydaw","doi":"10.2147/OPTH.S539635","DOIUrl":"10.2147/OPTH.S539635","url":null,"abstract":"<p><strong>Purpose: </strong>A retrospective study to determine the incidence of posterior ocular astigmatism (POA) after removal of topography guided excimer laser ablation utilizing topography measured astigmatism and axis to remove anterior corneal astigmatism and measure residual astigmatism in 1500 eyes.</p><p><strong>Methods: </strong>WaveLight Contoura was performed with topography measured astigmatism and axis, and all inaccurate outcomes were analyzed for the presence of low topographic astigmatism and significant residual manifest astigmatism. A secondary enhancement procedure was then performed, and measurements taken to measure the presence of topography measured astigmatism and the lack of manifest astigmatism to confirm that POA had been present.</p><p><strong>Results: </strong>Out of the 1500 eyes, 44 were confirmed to have POA, resulting in an incidence of 2.93%. The average amount of manifest astigmatism in these eyes post-primary procedure was 1.13D, and the average topography measured astigmatism was 0.39D. After secondary enhancement with wavefront optimized ablation, the average amount of post-operative astigmatism was 0.01D, and the average amount of topography measured astigmatism was 1.11D. Post-secondary enhancement procedure, average higher-order aberration was reduced 9%.</p><p><strong>Conclusion: </strong>The incidence of 2.93% is lower than prior estimated amounts of posterior ocular astigmatism.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2671-2679"},"PeriodicalIF":0.0,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Patient-Reported Outcomes After Mix-and-Match Implantation of a Trifocal and Non-Diffractive Extended Depth of Focus IOL.","authors":"Irene S Zhou, Dagny C Zhu","doi":"10.2147/OPTH.S533091","DOIUrl":"10.2147/OPTH.S533091","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate cataract surgery outcomes following mix-and-match implantation of a trifocal and extended-depth-of-focus (EDOF) intraocular lens (IOL).</p><p><strong>Setting: </strong>Single center, private practice.</p><p><strong>Design: </strong>Single arm, non-interventional, ambispective study.</p><p><strong>Methods: </strong>Patients who underwent femtosecond-laser assisted cataract surgery with mix-and-match implantation of the Clareon PanOptix trifocal IOL in the non-dominant eye and Clareon Vivity EDOF IOL in the dominant eye from September 2022 to November 2023 were reviewed. Only healthy eyes with postoperative absolute spherical equivalent (SE) ≤ 0.50 diopters (D) and cylinder ≤ 0.75 D were included. At 3 months postoperatively, binocular corrected and uncorrected visual acuity at distance (CDVA and UDVA), intermediate (DCIVA and UIVA), and near (DCNVA and UNVA) along with patient-reported outcomes (QUVID and IOLSAT questionnaires) were assessed.</p><p><strong>Results: </strong>100 eyes of 50 patients were included. Postoperatively, the mean binocular CDVA and UDVA was -0.08 ± 0.05 logMAR and -0.06 ± 0.05 logMAR, respectively. Overall, 100%, 98%, and 90% of patients achieved binocular UDVA, UIVA, and UNVA of 20/25 or better, respectively. Eighty-four percent of patients reported complete spectacle independence. Few patients were \"bothered very much\" by haloes, glare, or starbursts (0-4%). No patients reported dissatisfaction with their vision. Overall, 94% and 92% of patients would elect the same IOLs and recommend the same procedure to friends and family, respectively.</p><p><strong>Conclusion: </strong>Mix-and-match implantation of the Clareon PanOptix and Vivity IOLs yields good patient satisfaction potentially by combining the advantages of each lens resulting in a high degree of satisfaction and low rates of visual disturbances.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2625-2635"},"PeriodicalIF":0.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12345935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence Improves Patient Follow-Up in a Diabetic Retinopathy Screening Program [Letter].","authors":"Avi P Bhavsar, Charles I Minerd, Niloofar Piri","doi":"10.2147/OPTH.S537960","DOIUrl":"10.2147/OPTH.S537960","url":null,"abstract":"","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2659-2660"},"PeriodicalIF":0.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Surgical Outcome of Pterygium Excision and Conjunctival Limbal Autograft: Minimum 11 years Follow-up Study in a Country with High Ultraviolet Exposure.","authors":"Hisham M Jammal, Rami Al-Omari, Zaki Shannak, Shadi Alkhatib, Hashem Abu Serhan","doi":"10.2147/OPTH.S542804","DOIUrl":"10.2147/OPTH.S542804","url":null,"abstract":"<p><strong>Objective: </strong>To assess the long-term surgical outcome and complications in patients who underwent pterygium excision with conjunctival limbal autograft at least 11 years after surgery in a country with high ultraviolet light exposure.</p><p><strong>Material and methods: </strong>This was a long-term, cross-sectional, observational follow-up study of 15 patients with primary or recurrent pterygium who underwent surgery at King Abdullah University Hospital, Jordan, between June 2005 and June 2012. Data regarding the patients' satisfaction with the results, use of protective sunglasses, and daily sunlight exposure over the long-term period after surgery were collected. Recruited patients were then examined for pterygium recurrence and graft bed cosmesis. Primary outcome was the recurrence rate of pterygium. Secondary outcomes included graft bed appearance (cosmesis), patient-reported satisfaction, and long-term postoperative complications.</p><p><strong>Results: </strong>The mean (SD) age of the patients at the follow-up was 50 (8.8) years (range: 34-66 years), and the mean (SD) follow-up duration was 13.1 (1.5) years (range: 11-16 years). There was one case of recurrence (6.7%) and one case of symblepharon at the harvested graft site. Eleven out of the 15 patients reported being completely satisfied with the outcome of the surgery (mean score of 9.7 out of 10, SD: 1.0, range: 7-10). Seven patients reported daily sunlight exposure of more than three hours, and most of them were not regular users of protective sunglasses.</p><p><strong>Conclusion: </strong>The long-term follow-up, pterygium excision with conjunctival limbal autograft was found to be safe and effective in a country with high ultraviolet exposure.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2661-2669"},"PeriodicalIF":0.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Internal Limiting Membrane Flap Enhances Macular Hole Closure Rates in Highly Myopic Eyes: A Case-Control Study.","authors":"Stanley S J Poh, Andrew S H Tsai, Hung-Da Chou, Miao Li Chee, Chung-Ting Wang, Daniel S W Ting, Chi-Chun Lai, Shu Yen Lee","doi":"10.2147/OPTH.S517929","DOIUrl":"10.2147/OPTH.S517929","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the anatomical and functional outcomes of macular hole (MH) surgery in high myopia (HM) versus non-HM eyes.</p><p><strong>Patient and methods: </strong>This is a retrospective case-control study of patients who underwent MH repair between 2018 and 2022. HM was defined by axial length (AL) ≥26 mm. MH size, macular curvature and foveoschisis were graded. Surgical technique was divided into internal limiting membrane (ILM) peel or flap. Post-operative best corrected visual acuity (BCVA) and anatomical outcomes including hole closure, restoration of outer retinal layers, presence of foveal gliosis or foveal detachment were assessed at post-operative one, three, six and twelve months.</p><p><strong>Results: </strong>Thirty-four HM eyes were matched 1:1 to 34 out of 201 non-HM eyes with using gender, age, MH size and concurrent phacoemulsification as covariates. Mean AL in the HM group was 28.46 ± 2.01 mm, ranging from 26.03 to 32.83 mm. MH size was 366±183 µm and 386±199 µm in HM and non-HM groups (p=0.667). BCVA and restoration of outer retinal layers were comparable between groups at all time points. Initial hole closure rate was comparable, with 29 (85.3%) in HM group vs 30 (88.2%) in non-HM eyes, p=0.720. One eye in the HM group re-opened 10 months post-operatively. Proportion of eyes with non-closure was higher in those who underwent ILM peel vs flap [7/34 (20.5%) vs 0/34 (0%), p=0.022]. Smaller MH was associated with better closure rate (OR 0.99, 95% CI 0.99-1.00). AL and macular curvature were not associated with hole closure (OR 0.91, 95% CI 0.72-1.15; OR 1.01, 95% CI 0.99-1.02 respectively). Larger MH was associated with poorer final BCVA (β=0.010, 95% CI 0.007-0.014).</p><p><strong>Conclusion: </strong>Anatomical success was comparable between HM and non-HM eyes. Higher surgical success was associated with smaller MH size and ILM flap, but not influenced by AL, macular curvature or foveoschisis.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2615-2624"},"PeriodicalIF":0.0,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144839397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discordance Among Patients and Ophthalmologists Regarding the Burden of Intravitreal Injections.","authors":"Katie Robinson, Simon J Cooper, Sasha Persaud, Jennifer L Frederick, Rishi P Singh","doi":"10.2147/OPTH.S532179","DOIUrl":"10.2147/OPTH.S532179","url":null,"abstract":"<p><strong>Purpose: </strong>To determine how patients with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) perceive their disease and its treatment and to assess the degree of alignment between patient and clinician perceptions.</p><p><strong>Patients and methods: </strong>In June 2024 a survey of 101 patients (50 with DME and 51 with nAMD) and 100 ophthalmologists who treat these conditions completed surveys.</p><p><strong>Results: </strong>Sixty-six percent and 86% of patients with DME and nAMD, respectively, reported receiving intravitreal injections at least once every 8 weeks. Eighty-two percent required a caregiver and/or public transportation to get to their appointments. The most significant symptoms for patients with DME were vision loss over time (2.89 out of 4.0) and blurred or double vision (2.76), and for those with nAMD were poor night vision (3.43), seeing in low-light conditions (3.27), and blurred vision (2.96). The proportion of patients who were dissatisfied with the education and counseling they received about their disease was greater for nAMD (31%) compared with DME (11%; <i>P</i> < 0.01). Ophthalmologists overestimated the extent to which patients perceived that injections were necessary (mean Likert scale score 3.41 vs 3.00; <i>P</i> < 0.01) and that patients experienced insurance barriers to receiving treatment (3.00 vs 2.46; <i>P</i> < 0.01). They overestimated the extent to which patients became less nervous with subsequent injections after the first (3.40 vs 2.94; <i>P</i> < 0.01) and underestimated their difficulty of getting to appointments (2.30 vs 2.64; <i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>This study highlights the significant burden experienced by patients undergoing intravitreal injections and identifies key areas of discordance between patient and clinician perceptions. Targeted education and counseling focused on these differences is indicated to improve patient satisfaction and outcomes.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"2637-2645"},"PeriodicalIF":0.0,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144839395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}