Clinical EEG and neuroscience最新文献_第2页

Perinatal Hypoxic-hypoglycemic Injury and Epilepsy: A Comprehensive Analysis of Clinical and Laboratory Data in Adults. 围产期缺氧-低血糖损伤与癫痫：成人临床和实验室数据的综合分析。

Clinical EEG and neuroscience Pub Date : 2025-07-01 Epub Date: 2024-12-26 DOI: 10.1177/15500594241308592

Ozge Berna Gultekin Zaim, Rahsan Gocmen, Nese Dericioglu

{"title":"Perinatal Hypoxic-hypoglycemic Injury and Epilepsy: A Comprehensive Analysis of Clinical and Laboratory Data in Adults.","authors":"Ozge Berna Gultekin Zaim, Rahsan Gocmen, Nese Dericioglu","doi":"10.1177/15500594241308592","DOIUrl":"10.1177/15500594241308592","url":null,"abstract":"Objective. Perinatal hypoxia and/or hypoglycemia (PHH) is a serious condition leading to many neonatal deaths worldwide. It causes motor and cognitive deficits, visual disturbances, and seizures in survivors. There is limited information on the clinical course of seizures, EEG and MRI findings in adults. Methods. Adult patients with epilepsy due to PHH were included. Data on patients' demographic and clinical features, age at seizure onset, type and frequency of seizures, antiseizure medications and EEG features were extracted from electronic health records. Seizure outcome was classified as \"seizure-free for at least one year at last follow up\" versus \"continuing seizures\". Clinical and laboratory variables that could be associated with seizure outcome were investigated statistically in a subset of patients. Results. Forty-one patients (median age: 32 years) were included. Bilateral cerebral lesions, predominantly affecting the posterior regions, were present in 88% of the cases. Almost 80% experienced focal to bilateral tonic-clonic seizures. Approximately 60% of patients were on polytherapy. Half of the patients were seizure free at last follow-up. Seizure frequency decreased over time in 75% of the cohort. EEG demonstrated background slowing in 44% of patients, with epileptic discharges detected in 27%. The only variable correlated with seizure freedom was older age at seizure onset (P = .034). Conclusion. Almost half of the patients may reach seizure freedom. Seizure frequency decreases in 75% over time. Cranial MRI or EEG findings are not correlated with seizure outcomes. The only variable associated with seizure freedom at last follow up is older age at seizure onset.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"372-379"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microstate Analysis of Resting-State EEG Signals for Classifying Tinnitus from Healthy Subjects. 静息状态脑电图信号的微态分析与健康耳鸣分类。

Clinical EEG and neuroscience Pub Date : 2025-06-30 DOI: 10.1177/15500594251352252

Faezeh Mousazadeh Sarghein, Nasser Samadzadehaghdam, Faegheh Golabi, Fahimeh Mohagheghian, Tahereh Ghadiri

{"title":"Microstate Analysis of Resting-State EEG Signals for Classifying Tinnitus from Healthy Subjects.","authors":"Faezeh Mousazadeh Sarghein, Nasser Samadzadehaghdam, Faegheh Golabi, Fahimeh Mohagheghian, Tahereh Ghadiri","doi":"10.1177/15500594251352252","DOIUrl":"https://doi.org/10.1177/15500594251352252","url":null,"abstract":"Background: Electroencephalography (EEG) is a noninvasive technique for studying brain electrophysiology with high temporal resolution. Microstate analysis examines EEG recordings as a succession of quasi-stable microstates, allowing evaluation of extensive brain network activity linked to neuropsychiatric disorders like tinnitus. Objective: This study distinguishes tinnitus patients from healthy controls by using features acquired by microstate analysis. Methods: This study investigated EEG microstate differences between 16 healthy controls and 10 tinnitus patients. Four microstates were extracted and analyzed using Multivariate Analysis of Variance (MANOVA), revealing significant differences in duration, coverage, and occurrence between groups. Machine learning algorithms, including support vector machine (SVM) and K-Nearest Neighbors (KNN), and others were employed to classify tinnitus patients based on microstate features, achieving high accuracy, precision, specificity, recall, and F1-score. Results: MANOVA analysis revealed a significant difference in the duration of microstate A, which is associated with phonological processing and auditory perception, between the two groups. Additionally, significant differences in the coverage and occurrence of microstate B, related to visual networks, were observed. The SVM classifier achieved the highest accuracy of 96.44% in differentiating tinnitus patients from healthy controls, with impressive precision (97.64%), specificity (95.62%), and F1-score (97.24%). KNN also performed well, achieving a maximum recall of 97.24%. Conclusion: This study reveals the potential of EEG microstate analysis, incorporating time-related features, to improve tinnitus diagnosis and classification. Using SVM and KNN, we achieve high accuracy in identifying tinnitus-associated brain patterns, highlighting the clinical utility of EEG for neurological disease management.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"15500594251352252"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypersynchronous EEG Patterns in a Patient with Holoprosencephaly. 前脑无裂畸形患者的超同步脑电图模式。

Clinical EEG and neuroscience Pub Date : 2025-05-30 DOI: 10.1177/15500594251346337

Vishal Pandya, Doris Deng, Siddharth Gupta

{"title":"Hypersynchronous EEG Patterns in a Patient with Holoprosencephaly.","authors":"Vishal Pandya, Doris Deng, Siddharth Gupta","doi":"10.1177/15500594251346337","DOIUrl":"10.1177/15500594251346337","url":null,"abstract":"Holoprosencephaly is a congenital malformation of the central nervous system resulting from failure of the rostral neural tube to bifurcate into the two cerebral hemispheres. Deep brain structures including the thalamus, hypothalamus, and basal ganglia can also be affected to varying degrees. Here we present a patient with a rare de novo pathogenic variant in the PPP1R12A gene and the middle interhemispheric (MIH) variant of holoprosencephaly with hypersynchronous patterns on electroencephalography (EEG). The most prevalent abnormal pattern was abundant hypersynchronous rhythmic theta activity most prominent over the bilateral centro-parietal regions. There was also frequent hypersynchronous rhythmic beta activity and rhythmic alpha range activity, which occurred both synchronously and asynchronously. Finally, there were occasional periods of voltage attenuation interrupting hypersynchronous theta activity. While hypersynchronous theta activity and episodic attenuation have been previously described in alobar and semilobar variants of holoprosencephaly, our report is the first to describe these findings in a patient with the MIH variant as well as the first to describe EEG patterns in a patient with a pathogenic variant in the PPP1R12A gene mutations in which are associated with urogenital and/or brain malformation syndrome. Additionally, the hypersynchronous alpha activity is the first report of such an EEG pattern in holoprosencephaly. In order to develop a more complete understanding of EEG patterns in holoprosencephaly further study is needed but this is challenged by the relative rarity of the disease.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"15500594251346337"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroencephalography in China: Spread, Development and Prospects. 脑电图在中国的传播、发展与展望。

Clinical EEG and neuroscience Pub Date : 2025-05-19 DOI: 10.1177/15500594251343170

Yutong Yao, Yan Cui, Kaile Wang, Yunwei Chen, Ruxiang Xu

引用次数: 0

Infralow Activity on Intracranial EEG: A Systematic Review: Characteristics, Recording Methods and Predictive Value of the Zone to Remove. 颅内脑电图的次波活动：一项系统综述：特征、记录方法和待去除区域的预测价值。

Clinical EEG and neuroscience Pub Date : 2025-05-02 DOI: 10.1177/15500594251336845

Rene Andrade Machado, Sarah E Otterson

{"title":"Infralow Activity on Intracranial EEG: A Systematic Review: Characteristics, Recording Methods and Predictive Value of the Zone to Remove.","authors":"Rene Andrade Machado, Sarah E Otterson","doi":"10.1177/15500594251336845","DOIUrl":"https://doi.org/10.1177/15500594251336845","url":null,"abstract":"ObjectivesWe aimed to clarify the occurrence pattern of icDCs (ictal direct-current shifts), its recording parameters, polarity, and amplitude and to elucidate whether icDCs correlated with histology and the resection of the core area of icDCs is associated with favorable outcomes. Methods We carried out a systematic review according to the PRISMA statement. We searched for studies describing intracranial direct current shift, intracranial slow potential shift (SPS), or intracranial infralow activity AND surgical outcome. Results There is a marked heterogenicity in the recording parameters of icDCs, and in the method of intracranial evaluation (SEEG, subdural electrodes or both); icDCs can be obtained in more than 90% of patients with epilepsy evaluated with intracranial electrodes and in more than 90% of the seizures; icDCs is an electrical phenomenon with very high amplitude, with positive or negative polarity and prolonged duration, seen before or during seizure onset; IcDCs are best recorded with a time constant of 10 s, and setting LFF at 0.01 to 0.016 Hz and variable HFF; it seems preferable to evaluate them with an epoch of 300 s. IcDCs are not specific to any subjacent pathology. icDCs increases the probability of being seizure-free by 30.5. Conclusion Infralow activity can be assessed during intracranial recording with sEEG or subdural electrodes. Infralow activity is a prolonged baseline shift, with a very high amplitude appearing before or with the seizure onset. This might not be related to the subjacent pathology, but it helps delineate the zone to remove.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"15500594251336845"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EEG Oscillatory Activity and Resting-State Networks Associated with Neurocognitive Function in Mild Traumatic Brain Injury. 与轻度脑外伤神经认知功能相关的脑电图振荡活动和静息状态网络。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-10-18 DOI: 10.1177/15500594241290858

Masaya Ueda, Keita Ueno, Takuma Yuri, Yasunori Aoki, Masahiro Hata, Takao Inoue, Ryouhei Ishii, Yasuo Naito

{"title":"EEG Oscillatory Activity and Resting-State Networks Associated with Neurocognitive Function in Mild Traumatic Brain Injury.","authors":"Masaya Ueda, Keita Ueno, Takuma Yuri, Yasunori Aoki, Masahiro Hata, Takao Inoue, Ryouhei Ishii, Yasuo Naito","doi":"10.1177/15500594241290858","DOIUrl":"10.1177/15500594241290858","url":null,"abstract":"This study aimed to investigate the characteristics of resting-state electroencephalography (EEG) activity and brain networks in patients with mild traumatic brain injury (mTBI) and their association with neurocognitive function (NCF). We analyzed 26 patients with subacute mTBI and 21 healthy controls. The subacute mTBI group (9 females, 17 males) had a mean age of 29.9 ± 9.9 years, and the healthy controls (11 females, 10 males) had a mean age of 29.7 ± 11.5 years. Current source density, lagged phase synchronization, and resting-state network activity were analyzed using exact low-resolution electromagnetic tomography (eLORETA) with 60 s resting-state EEG data. In addition, a correlation analysis was performed between these EEG parameters and NCF in patients with mTBI. We used the statistical nonparametric mapping method in eLORETA to correct for multiple comparisons. There were no significant differences in EEG parameters between the patients with mTBI and healthy controls. However, in patients with mTBI, correlation analysis revealed negative correlations between theta activity in the anterior cingulate cortex and verbal short-term memory and between activity in the memory perception network and verbal memory. Our findings suggest that resting-state EEG may be clinically useful in investigating the mechanism of NCF decline in patients with mTBI.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"271-281"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142483188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

P3a, P3b Characteristics of OSA Patients in the Acute Stroke Population. P3a、P3b 急性中风人群中 OSA 患者的特征。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2025-02-17 DOI: 10.1177/15500594251319079

Pingshu Zhang, Hongchun Qian, Jianxin Yuan, Ya Ou, Xiaodong Yuan, Lingyun Cao, Liqin Duan, Qirong Ling

{"title":"P3a, P3b Characteristics of OSA Patients in the Acute Stroke Population.","authors":"Pingshu Zhang, Hongchun Qian, Jianxin Yuan, Ya Ou, Xiaodong Yuan, Lingyun Cao, Liqin Duan, Qirong Ling","doi":"10.1177/15500594251319079","DOIUrl":"10.1177/15500594251319079","url":null,"abstract":"Objective: To investigate the neurophysiological and cognitive impairments in patients with obstructive sleep apnea (OSA) among the acute stroke population. Methods: A total of 268 acute ischemic stroke patients with OSA underwent sleep monitoring within 24 h of admission and event-related potential tests within three days. They were categorized into groups based on their AHI: stroke only, and stroke with mild, moderate, or severe OSA. This classification served to analyze the electrophysiological profiles associated with stroke and OSA severity. Results: Compared with the control group, in the P3b series, the P3b-FZ amplitude was significantly reduced in the stroke with mild, moderate, and severe OSA group; the N2-PZ latency was significantly prolonged in the stroke with severe OSA group; and the P3b-FZ, P3b-CZ, and P3b-FZ latencies were significantly prolonged in the stroke with mild, moderate, and severe OSA group; in the P3a series, the N2-CZ amplitude was decreased in the stroke with severe OSA group, P2-FZ latency was significantly prolonged in the stroke with mild and moderate OSA group, P3a-FZ latency was significantly prolonged in the stroke with mild OSA group, P3a-CZ latency was significantly prolonged in the stroke with severe OSA group, and P3a-PZ latency was significantly prolonged in the stroke with mild and severe OSA group. Conclusions: The electrophysiologic changes compared with the stroke-only group were mainly characterized by prolonged latencies of the endogenous components P3a and P3b, suggesting that they are related to attention allocation and cognitive control.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"249-262"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artifacts Deceive: The Electroretinogram in the Electroencephalogram of a teenager with cerebral anoxia. 伪影欺骗：脑缺氧青少年脑电图中的视网膜电图。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-11-03 DOI: 10.1177/15500594241284679

Sonal Bhatia

引用次数: 0

Multimodal Neuroimaging in the Prediction of Deep TMS Response in OCD. 多模态神经成像在预测强迫症深度 TMS 反应中的应用

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-11-20 DOI: 10.1177/15500594241298977

Murat Aşık, Reyhan İlhan, Mehmet Güven Günver, Özden Orhan, Muhammed Taha Esmeray, Öznur Kalaba, Mehmet Kemal Arıkan

{"title":"Multimodal Neuroimaging in the Prediction of Deep TMS Response in OCD.","authors":"Murat Aşık, Reyhan İlhan, Mehmet Güven Günver, Özden Orhan, Muhammed Taha Esmeray, Öznur Kalaba, Mehmet Kemal Arıkan","doi":"10.1177/15500594241298977","DOIUrl":"10.1177/15500594241298977","url":null,"abstract":"Backgrounds: Brain morphological biomarkers could contribute to understanding the treatment response in patients with obsessive-compulsive disorder (OCD). Multimodal neuroimaging addresses this issue by providing more comprehensive information regarding neural processes and structures. Objectives. The present study aims to investigate whether patients responsive to deep Transcranial Magnetic Stimulation (TMS) differ from non-responsive individuals in terms of electrophysiology and brain morphology. Secondly, to test whether multimodal neuroimaging is superior to unimodal neuroimaging in predicting response to deep TMS. Methods. Thirty-two OCD patients who underwent thirty sessions of deep TMS treatment were included in the study. Based on a minimum 50% reduction in Yale-Brown Obsessive Compulsive Scale (Y-BOCS) scores after treatment, patients were grouped as responders (n = 25) and non-responders (n = 7). The baseline resting state qEEG and magnetic resonance imaging (MRI) records of patients were recorded. Independent sample t-test is used to compare the groups. Then, three logistic regression model were calculated for only QEEG markers, only MRI markers, and both QEEG/MRI markers. The predictive values of the three models were compared. Results. OCD patients who responded to deep TMS treatment had increased Alpha-2 power in the left temporal area and increased volume in the left temporal pole, entorhinal area, and parahippocampal gyrus compared to non-responders. The logistic regression model showed better prediction performance when both QEEG and MRI markers were included. Conclusions. This study addresses the gap in the literature regarding new functional and structural neuroimaging markers and highlights the superiority of multimodal neuroimaging to unimodal neuroimaging techniques in predicting treatment response.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"207-216"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142678035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurofeedback Reduces P300 Amplitudes to Intensely Emotive Pictures in Depressed Cancer Patients. 神经反馈可降低抑郁症癌症患者对强烈情感图片的 P300 振幅。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-10-21 DOI: 10.1177/15500594241287961

Marvin Krawutschke, Martin Teufel, Kira Schmidt, Saskia Pasche, Theresa Schweig, Anna Bialek, Axel Kowalski, Mitra Tewes, Martin Schuler, Dirk Schadendorf, Norbert Scherbaum, Eva-Maria Skoda, Madeleine Fink, Bernhard W Müller

{"title":"Neurofeedback Reduces P300 Amplitudes to Intensely Emotive Pictures in Depressed Cancer Patients.","authors":"Marvin Krawutschke, Martin Teufel, Kira Schmidt, Saskia Pasche, Theresa Schweig, Anna Bialek, Axel Kowalski, Mitra Tewes, Martin Schuler, Dirk Schadendorf, Norbert Scherbaum, Eva-Maria Skoda, Madeleine Fink, Bernhard W Müller","doi":"10.1177/15500594241287961","DOIUrl":"10.1177/15500594241287961","url":null,"abstract":"Objective. Electroencephalographic neurofeedback (EEG NF) or its effects on event-related potentials (ERPs) in quantitative EEG have not yet been systematically studied in cancer patients. The aim of this study was to investigate the emotional arousal and valence effects on the event-related P300 in a visual oddball paradigm by an individualized EEG alpha and theta/beta NF intervention in cancer patients and survivors (N = 18, age between 31 and 73 years). Methods. ERPs to low and high arousal target stimuli with either emotional positive or negative content and depressive state were obtained in cancer patients before and after a five-week NF intervention in a waitlist paradigm, following the consensus on the reporting and experimental design of clinical and cognitive-behavioral NF studies (CRED-nf checklist). Results. Overall, P300 amplitudes decreased significantly (p < .05) from pre to post therapy. Effects concerning high arousal stimuli with negative and positive valences were on the border to significance. Moreover, patients achieved significant relief of depressive symptoms (p < .05). Especially younger participants (<55 yrs.) benefited. Conclusions. P300 observations could reflect a therapeutic effect on brain activity level. EEG NF alleviates depressive symptoms in cancer patients. Significance. Based on these findings, further studies are needed to investigate the effects on event-related potentials by NF therapy.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"217-229"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142483189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0