Clinical EEG and neuroscience最新文献_第2页

Hypersynchronous EEG Patterns in a Patient with Holoprosencephaly. 前脑无裂畸形患者的超同步脑电图模式。

Clinical EEG and neuroscience Pub Date : 2025-05-30 DOI: 10.1177/15500594251346337

Vishal Pandya, Doris Deng, Siddharth Gupta

{"title":"Hypersynchronous EEG Patterns in a Patient with Holoprosencephaly.","authors":"Vishal Pandya, Doris Deng, Siddharth Gupta","doi":"10.1177/15500594251346337","DOIUrl":"10.1177/15500594251346337","url":null,"abstract":"Holoprosencephaly is a congenital malformation of the central nervous system resulting from failure of the rostral neural tube to bifurcate into the two cerebral hemispheres. Deep brain structures including the thalamus, hypothalamus, and basal ganglia can also be affected to varying degrees. Here we present a patient with a rare de novo pathogenic variant in the PPP1R12A gene and the middle interhemispheric (MIH) variant of holoprosencephaly with hypersynchronous patterns on electroencephalography (EEG). The most prevalent abnormal pattern was abundant hypersynchronous rhythmic theta activity most prominent over the bilateral centro-parietal regions. There was also frequent hypersynchronous rhythmic beta activity and rhythmic alpha range activity, which occurred both synchronously and asynchronously. Finally, there were occasional periods of voltage attenuation interrupting hypersynchronous theta activity. While hypersynchronous theta activity and episodic attenuation have been previously described in alobar and semilobar variants of holoprosencephaly, our report is the first to describe these findings in a patient with the MIH variant as well as the first to describe EEG patterns in a patient with a pathogenic variant in the PPP1R12A gene mutations in which are associated with urogenital and/or brain malformation syndrome. Additionally, the hypersynchronous alpha activity is the first report of such an EEG pattern in holoprosencephaly. In order to develop a more complete understanding of EEG patterns in holoprosencephaly further study is needed but this is challenged by the relative rarity of the disease.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"15500594251346337"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroencephalography in China: Spread, Development and Prospects. 脑电图在中国的传播、发展与展望。

Clinical EEG and neuroscience Pub Date : 2025-05-19 DOI: 10.1177/15500594251343170

Yutong Yao, Yan Cui, Kaile Wang, Yunwei Chen, Ruxiang Xu

引用次数: 0

Infralow Activity on Intracranial EEG: A Systematic Review: Characteristics, Recording Methods and Predictive Value of the Zone to Remove. 颅内脑电图的次波活动：一项系统综述：特征、记录方法和待去除区域的预测价值。

Clinical EEG and neuroscience Pub Date : 2025-05-02 DOI: 10.1177/15500594251336845

Rene Andrade Machado, Sarah E Otterson

{"title":"Infralow Activity on Intracranial EEG: A Systematic Review: Characteristics, Recording Methods and Predictive Value of the Zone to Remove.","authors":"Rene Andrade Machado, Sarah E Otterson","doi":"10.1177/15500594251336845","DOIUrl":"https://doi.org/10.1177/15500594251336845","url":null,"abstract":"ObjectivesWe aimed to clarify the occurrence pattern of icDCs (ictal direct-current shifts), its recording parameters, polarity, and amplitude and to elucidate whether icDCs correlated with histology and the resection of the core area of icDCs is associated with favorable outcomes. Methods We carried out a systematic review according to the PRISMA statement. We searched for studies describing intracranial direct current shift, intracranial slow potential shift (SPS), or intracranial infralow activity AND surgical outcome. Results There is a marked heterogenicity in the recording parameters of icDCs, and in the method of intracranial evaluation (SEEG, subdural electrodes or both); icDCs can be obtained in more than 90% of patients with epilepsy evaluated with intracranial electrodes and in more than 90% of the seizures; icDCs is an electrical phenomenon with very high amplitude, with positive or negative polarity and prolonged duration, seen before or during seizure onset; IcDCs are best recorded with a time constant of 10 s, and setting LFF at 0.01 to 0.016 Hz and variable HFF; it seems preferable to evaluate them with an epoch of 300 s. IcDCs are not specific to any subjacent pathology. icDCs increases the probability of being seizure-free by 30.5. Conclusion Infralow activity can be assessed during intracranial recording with sEEG or subdural electrodes. Infralow activity is a prolonged baseline shift, with a very high amplitude appearing before or with the seizure onset. This might not be related to the subjacent pathology, but it helps delineate the zone to remove.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"15500594251336845"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EEG Oscillatory Activity and Resting-State Networks Associated with Neurocognitive Function in Mild Traumatic Brain Injury. 与轻度脑外伤神经认知功能相关的脑电图振荡活动和静息状态网络。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-10-18 DOI: 10.1177/15500594241290858

Masaya Ueda, Keita Ueno, Takuma Yuri, Yasunori Aoki, Masahiro Hata, Takao Inoue, Ryouhei Ishii, Yasuo Naito

{"title":"EEG Oscillatory Activity and Resting-State Networks Associated with Neurocognitive Function in Mild Traumatic Brain Injury.","authors":"Masaya Ueda, Keita Ueno, Takuma Yuri, Yasunori Aoki, Masahiro Hata, Takao Inoue, Ryouhei Ishii, Yasuo Naito","doi":"10.1177/15500594241290858","DOIUrl":"10.1177/15500594241290858","url":null,"abstract":"This study aimed to investigate the characteristics of resting-state electroencephalography (EEG) activity and brain networks in patients with mild traumatic brain injury (mTBI) and their association with neurocognitive function (NCF). We analyzed 26 patients with subacute mTBI and 21 healthy controls. The subacute mTBI group (9 females, 17 males) had a mean age of 29.9 ± 9.9 years, and the healthy controls (11 females, 10 males) had a mean age of 29.7 ± 11.5 years. Current source density, lagged phase synchronization, and resting-state network activity were analyzed using exact low-resolution electromagnetic tomography (eLORETA) with 60 s resting-state EEG data. In addition, a correlation analysis was performed between these EEG parameters and NCF in patients with mTBI. We used the statistical nonparametric mapping method in eLORETA to correct for multiple comparisons. There were no significant differences in EEG parameters between the patients with mTBI and healthy controls. However, in patients with mTBI, correlation analysis revealed negative correlations between theta activity in the anterior cingulate cortex and verbal short-term memory and between activity in the memory perception network and verbal memory. Our findings suggest that resting-state EEG may be clinically useful in investigating the mechanism of NCF decline in patients with mTBI.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"271-281"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142483188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

P3a, P3b Characteristics of OSA Patients in the Acute Stroke Population. P3a、P3b 急性中风人群中 OSA 患者的特征。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2025-02-17 DOI: 10.1177/15500594251319079

Pingshu Zhang, Hongchun Qian, Jianxin Yuan, Ya Ou, Xiaodong Yuan, Lingyun Cao, Liqin Duan, Qirong Ling

{"title":"P3a, P3b Characteristics of OSA Patients in the Acute Stroke Population.","authors":"Pingshu Zhang, Hongchun Qian, Jianxin Yuan, Ya Ou, Xiaodong Yuan, Lingyun Cao, Liqin Duan, Qirong Ling","doi":"10.1177/15500594251319079","DOIUrl":"10.1177/15500594251319079","url":null,"abstract":"Objective: To investigate the neurophysiological and cognitive impairments in patients with obstructive sleep apnea (OSA) among the acute stroke population. Methods: A total of 268 acute ischemic stroke patients with OSA underwent sleep monitoring within 24 h of admission and event-related potential tests within three days. They were categorized into groups based on their AHI: stroke only, and stroke with mild, moderate, or severe OSA. This classification served to analyze the electrophysiological profiles associated with stroke and OSA severity. Results: Compared with the control group, in the P3b series, the P3b-FZ amplitude was significantly reduced in the stroke with mild, moderate, and severe OSA group; the N2-PZ latency was significantly prolonged in the stroke with severe OSA group; and the P3b-FZ, P3b-CZ, and P3b-FZ latencies were significantly prolonged in the stroke with mild, moderate, and severe OSA group; in the P3a series, the N2-CZ amplitude was decreased in the stroke with severe OSA group, P2-FZ latency was significantly prolonged in the stroke with mild and moderate OSA group, P3a-FZ latency was significantly prolonged in the stroke with mild OSA group, P3a-CZ latency was significantly prolonged in the stroke with severe OSA group, and P3a-PZ latency was significantly prolonged in the stroke with mild and severe OSA group. Conclusions: The electrophysiologic changes compared with the stroke-only group were mainly characterized by prolonged latencies of the endogenous components P3a and P3b, suggesting that they are related to attention allocation and cognitive control.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"249-262"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artifacts Deceive: The Electroretinogram in the Electroencephalogram of a teenager with cerebral anoxia. 伪影欺骗：脑缺氧青少年脑电图中的视网膜电图。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-11-03 DOI: 10.1177/15500594241284679

Sonal Bhatia

引用次数: 0

Multimodal Neuroimaging in the Prediction of Deep TMS Response in OCD. 多模态神经成像在预测强迫症深度 TMS 反应中的应用

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-11-20 DOI: 10.1177/15500594241298977

Murat Aşık, Reyhan İlhan, Mehmet Güven Günver, Özden Orhan, Muhammed Taha Esmeray, Öznur Kalaba, Mehmet Kemal Arıkan

{"title":"Multimodal Neuroimaging in the Prediction of Deep TMS Response in OCD.","authors":"Murat Aşık, Reyhan İlhan, Mehmet Güven Günver, Özden Orhan, Muhammed Taha Esmeray, Öznur Kalaba, Mehmet Kemal Arıkan","doi":"10.1177/15500594241298977","DOIUrl":"10.1177/15500594241298977","url":null,"abstract":"Backgrounds: Brain morphological biomarkers could contribute to understanding the treatment response in patients with obsessive-compulsive disorder (OCD). Multimodal neuroimaging addresses this issue by providing more comprehensive information regarding neural processes and structures. Objectives. The present study aims to investigate whether patients responsive to deep Transcranial Magnetic Stimulation (TMS) differ from non-responsive individuals in terms of electrophysiology and brain morphology. Secondly, to test whether multimodal neuroimaging is superior to unimodal neuroimaging in predicting response to deep TMS. Methods. Thirty-two OCD patients who underwent thirty sessions of deep TMS treatment were included in the study. Based on a minimum 50% reduction in Yale-Brown Obsessive Compulsive Scale (Y-BOCS) scores after treatment, patients were grouped as responders (n = 25) and non-responders (n = 7). The baseline resting state qEEG and magnetic resonance imaging (MRI) records of patients were recorded. Independent sample t-test is used to compare the groups. Then, three logistic regression model were calculated for only QEEG markers, only MRI markers, and both QEEG/MRI markers. The predictive values of the three models were compared. Results. OCD patients who responded to deep TMS treatment had increased Alpha-2 power in the left temporal area and increased volume in the left temporal pole, entorhinal area, and parahippocampal gyrus compared to non-responders. The logistic regression model showed better prediction performance when both QEEG and MRI markers were included. Conclusions. This study addresses the gap in the literature regarding new functional and structural neuroimaging markers and highlights the superiority of multimodal neuroimaging to unimodal neuroimaging techniques in predicting treatment response.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"207-216"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142678035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurofeedback Reduces P300 Amplitudes to Intensely Emotive Pictures in Depressed Cancer Patients. 神经反馈可降低抑郁症癌症患者对强烈情感图片的 P300 振幅。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-10-21 DOI: 10.1177/15500594241287961

Marvin Krawutschke, Martin Teufel, Kira Schmidt, Saskia Pasche, Theresa Schweig, Anna Bialek, Axel Kowalski, Mitra Tewes, Martin Schuler, Dirk Schadendorf, Norbert Scherbaum, Eva-Maria Skoda, Madeleine Fink, Bernhard W Müller

{"title":"Neurofeedback Reduces P300 Amplitudes to Intensely Emotive Pictures in Depressed Cancer Patients.","authors":"Marvin Krawutschke, Martin Teufel, Kira Schmidt, Saskia Pasche, Theresa Schweig, Anna Bialek, Axel Kowalski, Mitra Tewes, Martin Schuler, Dirk Schadendorf, Norbert Scherbaum, Eva-Maria Skoda, Madeleine Fink, Bernhard W Müller","doi":"10.1177/15500594241287961","DOIUrl":"10.1177/15500594241287961","url":null,"abstract":"Objective. Electroencephalographic neurofeedback (EEG NF) or its effects on event-related potentials (ERPs) in quantitative EEG have not yet been systematically studied in cancer patients. The aim of this study was to investigate the emotional arousal and valence effects on the event-related P300 in a visual oddball paradigm by an individualized EEG alpha and theta/beta NF intervention in cancer patients and survivors (N = 18, age between 31 and 73 years). Methods. ERPs to low and high arousal target stimuli with either emotional positive or negative content and depressive state were obtained in cancer patients before and after a five-week NF intervention in a waitlist paradigm, following the consensus on the reporting and experimental design of clinical and cognitive-behavioral NF studies (CRED-nf checklist). Results. Overall, P300 amplitudes decreased significantly (p < .05) from pre to post therapy. Effects concerning high arousal stimuli with negative and positive valences were on the border to significance. Moreover, patients achieved significant relief of depressive symptoms (p < .05). Especially younger participants (<55 yrs.) benefited. Conclusions. P300 observations could reflect a therapeutic effect on brain activity level. EEG NF alleviates depressive symptoms in cancer patients. Significance. Based on these findings, further studies are needed to investigate the effects on event-related potentials by NF therapy.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"217-229"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142483189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrocortical Profiles in Relation to Childhood Adversity and Depression Severity: A Preliminary Report. 与童年逆境和抑郁严重程度相关的皮质电图：初步报告

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-11-13 DOI: 10.1177/15500594241294021

Natalia Jaworska, Sara de la Salle, Bronwen Schryver, Meagan Birmingham, Jennifer L Phillips, Pierre Blier, Verner Knott

{"title":"Electrocortical Profiles in Relation to Childhood Adversity and Depression Severity: A Preliminary Report.","authors":"Natalia Jaworska, Sara de la Salle, Bronwen Schryver, Meagan Birmingham, Jennifer L Phillips, Pierre Blier, Verner Knott","doi":"10.1177/15500594241294021","DOIUrl":"10.1177/15500594241294021","url":null,"abstract":"Objective: Assessment of electroencephalographic (EEG) activity in depression has provided insights into neural profiles of the illness. However, there is limited understanding on how symptom severity and risk factors, such as childhood adversity, influence EEG features. Methods: Eyes-closed EEG was acquired in N = 28 depressed individuals being treated in a tertiary psychiatric setting. Absolute alpha, beta, theta, and delta power and inter-/intra-hemispheric coherence were examined. Relations between the Montgomery-Åsberg Depression Scale (MADRS) and Adverse Childhood Experience (ACE) Questionnaire and EEG features were assessed. Results: Individuals in the high (MADRS≥30) versus lower (MADRS ≤ 29) symptom severity group exhibited greater overall beta power, and lower Fp1-Fp2 delta and theta coherence. Those with high (≥3) versus lower (≤2) ACE scores exhibited greater T7-T8 beta coherence. Lowest F3-F4 beta coherence was observed in those with high ACE/high depression severity. A negative correlation existed between F8-P8 alpha coherence and symptom severity. Conclusions: Those with higher depression severity exhibit increased beta power, possibly reflecting a hyper-vigilant state. Depression severity and ACE history may produce subtle alterations in frontal delta/theta and temporal/frontal beta coherence regions. Significance: This is the first study to examine the neural impact of depression severity and ACE-assessed childhood trauma in depressed individuals receiving treatment in a tertiary setting, accounting for the clinical reality of the prevalence of their co-occurrence.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"230-238"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous Infantile Spasms and Focal Seizures: A Rarely Reported Combined Seizure Phenomenon on Video Electroencephalogram (VEEG). 婴儿痉挛和局灶性癫痫同时发作：视频脑电图 (VEEG) 上罕见的合并癫痫发作现象。

Clinical EEG and neuroscience Pub Date : 2025-05-01 Epub Date: 2024-10-15 DOI: 10.1177/15500594241289637

Katherine Horman, Sonal Bhatia

{"title":"Simultaneous Infantile Spasms and Focal Seizures: A Rarely Reported Combined Seizure Phenomenon on Video Electroencephalogram (VEEG).","authors":"Katherine Horman, Sonal Bhatia","doi":"10.1177/15500594241289637","DOIUrl":"10.1177/15500594241289637","url":null,"abstract":"Focal seizures (FS) have previously been described before or after infantile spasm (IS) clusters, but FS occurring simultaneously with an IS cluster has been rarely reported in the EEG literature. We present three cases where focal seizures (FS) occurred concurrently during an infantile spasm (IS) cluster on VEEG. On VEEG, onset of IS cluster preceded FS in all three patients; however, patient three was diagnosed with FS prior to the onset of IS. FS duration ranged from 10-90 s and was electrographic-only in two out of the three patients. Unfortunately, the first two patients are now deceased, and for patient two no etiology was ever identified. Currently, patient three is free of spasms as well as seizures but has global developmental delay; no definite etiology has been identified for their presentation. Concurrent FS with IS suggests that the seizure types may be generated in different brain areas with one seizure type potentially triggering the other and is generally reflective of multifocal or diffuse cerebral disease with a poor prognosis as was seen in at least two of our patients. Our three cases of IS where FS occurred concurrently contribute to the limited existing data describing this phenomenon on VEEG.","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"286-290"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142483190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0