{"title":"Error Related Negativity and Error Positivity: Neural Indices of Double-Faults in Elite Athletes.","authors":"Beren Çetiner, Baris Metin","doi":"10.1177/15500594261488077","DOIUrl":"10.1177/15500594261488077","url":null,"abstract":"<p><p>ObjectiveError-related negativity (ERN) and error positivity (Pe) are key neural responses of human error monitoring. However, their relationship to behavioral adjustments after the mistakes in speeded laboratory experiments has shown mixed results. The present study examined whether ERN and Pe amplitudes would be better predictors of performance recovery following an error in a sport context than in a speeded laboratory task.MethodsFifteen male professional basketball players (18-26 years) performed a letter-based Eriksen Flanker task while their brain activity was recorded using 32-channel electroencephalography (EEG). Then, they completed a standardized 100-shot free-throw protocol on their home court. Recovery in the laboratory was measured as the ratio of back-to-back errors to total errors in the Flanker task, while recovery on the court was measured as the ratio of consecutive missed free throws to total misses. Pearson correlations and linear regression analysis were used to examine how ERP magnitudes relate to each recovery measure.ResultsAlthough ERN and Pe amplitudes were not associated with the laboratory consecutive-error ratio (all <i>p values</i> >.05), they were significant predictors of the field consecutive-miss ratio. Athletes with larger Pe and ERN amplitudes had significantly fewer consecutive misses (<i>p</i> < .001 and <i>p</i> = .017).ConclusionsERN and Pe may be less relevant for predicting specific post-error adjustments to immediate task demands and more relevant for predicting overall regulatory capacity in ecologically valid settings. Our findings highlight the need to use real-world performance measures when linking error monitoring with the realm of athletic performance.</p>","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"520-528"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148972288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eli Heyman, Shlomo Gilat, Eli Lahat, Noa Levin, Revital Sheinberg, Matitiahu Berkovitch, Revital Gandelman-Marton
{"title":"The Effect of Levetiracetam on the Interictal EEG in Children with Refractory Epilepsy.","authors":"Eli Heyman, Shlomo Gilat, Eli Lahat, Noa Levin, Revital Sheinberg, Matitiahu Berkovitch, Revital Gandelman-Marton","doi":"10.1177/15500594261439207","DOIUrl":"10.1177/15500594261439207","url":null,"abstract":"<p><p>BackgroundInterictal epileptiform discharges (IED) frequency is the most commonly studied interictal measure of ASM efficacy in patients with epilepsy, and IED suppression in a repeat pediatric EEG is usually interpreted as a reduced tendency towards seizures.ObjectiveTo assess whether the amplitude and morphology of IED can serve as surrogate measures of levetiracetam (LEV) efficacy in children with drug-resistant epilepsy.MethodsPatients with refractory epilepsy, who were treated with oral LEV during a 5-year period, and who had at least 24 h long-term video-EEG recording (LTVEEG) before LEV was initiated and after attaining maximal dosage, were retrospectively selected from the database of the pediatric epilepsy clinic and LTVEEG monitoring unit. IED kurtosis (degree of peakedness), skewness (degree of asymmetry), and below-curve-area (area of the IED) were estimated by a signal processing analysis program.ResultsIED analysis in 20 patients aged 3.6 months to 15 years at maximal LEV dosage revealed increased kurtosis, increased skewness positivity and decreased below-curve-area compared to pre-treatment values. Visual analysis revealed a mean IED amplitude decrease in 30% of the patients, mainly in patients with generalized seizures. Neither the changes in IED measures nor the decrease of the visually determined IED amplitude correlated with decreased seizure frequency.ConclusionsIED amplitude, kurtosis, skewness and below-curve-area were not correlated with seizure outcome after LEV initiation. Further studies with larger samples and additional seizure outcome measures are warranted.</p>","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"559-564"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings of the 7th International Conference on Basic and Clinical Multimodal Imaging (BaCI) meeting, a joint meeting of EEG and Clinical Neuroscience Society (ECNS), the International Society for Brain Electromagnetic Topography (ISBET), the International Society for Functional Source Imaging (ISFSI), and the International Society for Neuroimaging in Psychiatry (ISNIP).","authors":"","doi":"10.1177/15500594261448097","DOIUrl":"10.1177/15500594261448097","url":null,"abstract":"","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"NP11-NP22"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brief Mindfulness Intervention Improved Self-Reported Acceptance but Not Neural or Behavioral Reactivity to Errors.","authors":"Xiaoqian Yu, Geoffrey F Potts","doi":"10.1177/15500594251393583","DOIUrl":"10.1177/15500594251393583","url":null,"abstract":"<p><p>Acceptance, nonjudgmental awareness of the present-moment experiences, is a central component of mindfulness. This study used a pretest-posttest design to examine whether a brief mindfulness intervention (MI) could increase self-reported acceptance and reduce affective reactivity to errors, as indexed by error-related negativity (ERN), error positivity (Pe), and post-error slowing (PES). Meditation-naïve participants (n = 121, ages 18-31 years, 69% female) were randomly assigned to either a mindfulness group, which engaged in 10 min of guided mindful breathing, or a control group, which listened to a Ted talk on green living. Both groups completed a Flanker task before and after the intervention to elicit errors under time pressure. Results showed that participants in the mindfulness group reported greater acceptance following the intervention; however, no corresponding changes were observed in ERN or PES. Instead, both groups showed practice effects, with faster reaction times and larger Pe amplitudes reflecting increased response certainty. These findings suggest that while a brief MI may enhance subjective acceptance, it may not be sufficient to alter neural or behavioral markers of affective error reactivity. Longer or more intensive mindfulness training may be required to influence these deeper cognitive and emotional processes.</p>","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"487-499"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shirenda Rizka Maulia, Anwar Ma'ruf, Ahmad Yudianto, Abdulloh Machin, Dian Eva Sanjaya
{"title":"Stress-Related q-EEG Abnormalities in Indonesian School Children: Considering the Role of Bullying.","authors":"Shirenda Rizka Maulia, Anwar Ma'ruf, Ahmad Yudianto, Abdulloh Machin, Dian Eva Sanjaya","doi":"10.1177/15500594251414823","DOIUrl":"10.1177/15500594251414823","url":null,"abstract":"<p><p>BackgroundPsychosocial stress-particularly bullying-has been recognized as a critical determinant of mental and neurophysiological health in children. Chronic stress exposure may disrupt cortical regulatory mechanisms detectable through quantitative electroencephalography (q-EEG).ObjectiveThis study examined the correlation between perceived psychological stress, involvement in bullying, and q-EEG spectral anomalies among Indonesian school-aged children, seeking to determine if bullying-related stress generates unique neurophysiological patterns or indicates a general dysregulation of stress responses.MethodsA two-phase design was implemented. Phase I included 2781 8-13-year-olds who completed the PSS-10 and a validated bullying questionnaire. Using a Mitsar-EEG 201 equipment, Phase II selected 24 students with increased stress levels (PSS ≥ 27) for q-EEG examination. Electroencephalogram signals from 19 scalp sites were converted into z-scores using age-adjusted NeuroGuide database standards. Stress level and brain activity were correlated using Spearman's rho.ResultsThe majority of subjects (23 out of 25; 95.8%) had EEG activity above ±2 standard deviations, especially in the temporal and prefrontal areas. There was a negative correlation between stress and temporal alpha power (r = -0.43, p = 0.028) and a positive correlation between stress with enhanced prefrontal high-beta power (r = 0.47, p = 0.021). Neurophysiological alterations among bullied children closely paralleled those under non-bullying stressors such as academic overload or family conflict.ConclusionElevated stress intensity, regardless of its psychosocial origin, was associated with convergent cortical dysregulation patterns. These results suggest that q-EEG may be a viable non-invasive method for early stress-related neurophysiological dysfunction diagnosis and that pediatric populations require integrated emotional regulation therapies.</p>","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"511-519"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146121422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical EEG In Modern Psychiatry: Diagnostics and Prediction.","authors":"Oliver Pogarell, Sebastian Olbrich","doi":"10.1177/15500594261471242","DOIUrl":"10.1177/15500594261471242","url":null,"abstract":"<p><p>Clinical electroencephalography (EEG) remains a central diagnostic tool in psychiatry. As a non-invasive, widely available and cost-effective method with high temporal resolution, EEG contributes to the detection of epileptiform activity, exclusion of organic brain dysfunction, assessment of delirium and encephalopathies, differential diagnosis of dementias, and monitoring of psychopharmacological treatments. It provides functional information that complements structural imaging and serves as an indispensable auxiliary tool in the diagnostic work up.While EEG has not demonstrated sufficient specificity as a diagnostic marker for primary psychiatric disorders, there is growing evidence supporting the predictive use of quantitative EEG features, particularly in depression. Resting-state markers, including alpha peak frequency, vigilance regulation and frontal alpha asymmetry have shown small-to-moderate effect sizes in predicting differential treatment responses to antidepressants, brain stimulation techniques, ketamine and electroconvulsive therapy. These markers operate probabilistically, shifting response likelihoods rather than determining outcomes at the individual level. Even modest predictive effects can translate into meaningful population-level improvements by reducing ineffective treatment trials and accelerating remission.In summary, electroencephalography is a valuable tool in routine clinical practice that should be part of standard diagnostic procedures. Subject to large validation studies, quantitative EEG can provide predictive instruments in precision psychiatry, enhance treatment selection and thus improve outcomes by augmenting the clinical nature of psychiatric practice.</p>","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"475-486"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fengjiao Liang, Xiang Chen, Baoying Li, Banghua Yang
{"title":"Brain-Computer Interface Combined with Functional Electrical Stimulation for Post-Stroke Upper Limb Motor Recovery: A Systematic Review and Meta-Analysis.","authors":"Fengjiao Liang, Xiang Chen, Baoying Li, Banghua Yang","doi":"10.1177/15500594261441055","DOIUrl":"10.1177/15500594261441055","url":null,"abstract":"<p><p>BackgroundBrain-computer interface-driven functional electrical stimulation (BCI-FES) is a promising approach for post-stroke upper limb rehabilitation. However, considerable variability exists in stimulation parameters and task designs across studies, and evidence remains insufficient to support definitive protocol recommendations.MethodsWe searched PubMed, Embase, Web of Science, and the Cochrane Library for randomized controlled trials (RCTs) up to September 2025. Eligible studies applied BCI-FES and reported the Fugl-Meyer Assessment for the upper extremity (FMA-UE). Risk of bias was assessed with the PEDro scale, and evidence certainty graded with GRADE. Random-effects meta-analyses were performed.ResultsTwelve RCTs (n = 619) showed BCI-FES improved FMA-UE scores versus controls (MD = 5.82, 95% CI 3.04-8.59, p < 0.00001; I<sup>2</sup> = 39%), with larger benefits in subacute stroke (MD = 8.45). Dynamic-threshold paradigms and motor imagery were associated with higher effect sizes. Higher stimulation frequency (>50 Hz), narrow-pulse width (150 µs) more frequent sessions (≥5/week), shorter session duration (≤30 min), greater total sessions (>20), and longer intervention (>4 weeks) tended to be associated with larger effect sizes, though evidence is limited and based on few studies. Secondary outcomes (ARAT, WMFT, MBI) improved, and no serious adverse events were reported. Evidence certainty was moderate.ConclusionBCI-FES was associated with improvements in upper limb motor recovery after stroke, especially in subacute patients. Some stimulation and training features may relate to greater effects, but current evidence remains insufficient for definitive clinical guidance. Larger multicenter RCTs are needed to clarify dose-response relationships and support biomarker-guided, personalized interventions.</p>","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"529-541"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early Ictal Dynamics in Childhood Absence Epilepsy: Scalp EEG Detection of Direct Current Shifts and High-Frequency Oscillations.","authors":"Keisuke Maeda, Shunta Yamaguchi, Himari Tsuboi, Naohiro Ichino, Keisuke Osakabe, Keiko Sugimoto, Gen Furukawa, Naoko Ishihara","doi":"10.1177/15500594261475856","DOIUrl":"10.1177/15500594261475856","url":null,"abstract":"<p><p>IntroductionAbsence seizures are characterized by the appearance of generalized spike-and-wave complexes (SWCs) on scalp electroencephalography (EEG), but the EEG-level physiological changes that precede the onset of SWCs remain poorly understood. Advances in scalp wide-band EEG have enabled the simultaneous visualization of ultraslow and high-frequency activity, providing an opportunity to examine early ictal dynamics in childhood absence epilepsy (CAE). Here, we report two cases of pediatric CAE in which scalp EEG captured ictal direct current (DC) shifts and ictal high-frequency oscillations (HFOs) within the same seizure epoch.Patients and MethodsWe report two pediatric patients with CAE who exhibited typical absence seizures during hyperventilation-provoked scalp EEG recordings. Across three seizures, the same wide-band EEG methodology enabled the evaluation of ictal DC shifts and HFOs.ResultsAcross three seizures, a reproducible temporal sequence was observed: a negative DC shift emerged several hundred milliseconds before the first SWC, followed by spike-locked HFOs shortly after ictal onset. The DC shift progressively deepened during this interval, whereas HFOs appeared as discrete, band-limited events with modest frequency evolution. Despite differences in seizure duration and clinical background, this pattern was consistent across seizures and between patients.DiscussionThese findings suggest that ictal DC shifts reflect slow network changes preceding thalamocortical hypersynchrony, whereas ictal HFOs index the fast dynamics involved in SWC generation. As both components can be detected noninvasively, scalp wide-band EEG may offer a foundation for developing early ictal biomarkers in CAE.</p>","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"574-579"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hyperkinetic Seizures in Insular and Insulo-Opercular Seizure Onset: A Systematic Review.","authors":"Rene Andrade Machado, Natasha Acosta Diaz, Satyanarayana Gedela","doi":"10.1177/15500594261455108","DOIUrl":"10.1177/15500594261455108","url":null,"abstract":"<p><p>ObjectiveTo describe demographics, semiology, etiology, and clinical features in individuals with insulo-opercular and pure insular onset presenting with hyperkinetic seizures (HKS).MethodsUnder PRISMA guidelines, Embase, PubMed, Medline, and Cochrane were searched for articles between 1969 and January 10, 2025, using terms for hyperkinetic/hypermotor seizures, insular epilepsy, sleep-related hypermotor epilepsy, nocturnal paroxysmal dyskinesia/dystonia, nocturnal frontal lobe epilepsy, and complex motor behavior. Eligible studies were reports or retrospective series of patients with pure insular or insulo-opercular epilepsy and HKS, documented with SEEG or subdural recordings, with at least 6 months of postsurgical follow-up and Engels class I. Of 271 studies, 14 met inclusion criteria.ResultsFourteen studies including 34 patients were analyzed; 61.8% had pure insular onset. Focal cortical dysplasia was the most common etiology, present in two-thirds of cases. Most HKS began with non-motor semiology (76.5%). Hyperkinetic automatisms type 3, defined by integrated/natural hyperkinetic behaviors, manipulation/utilization behaviors, and distal stereotypies, were reported in 49.9% of patients with pure insular onset. Compared with insulo-opercular onset, pure insular onset was associated with a higher frequency of these behaviors, along with agitation, vocalization, and breathing difficulties (p < 0.05). These findings are based on small, heterogeneous samples and should be interpreted cautiously.ConclusionHKS were more frequently associated with pure insular onset. Focal cortical dysplasia was the most common etiology, and integrated/natural hyperkinetic behavior was more frequent with pure insular onset. Given limited sample size, heterogeneity, and study design constraints, these findings should be considered exploratory rather than definitive.</p>","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"542-558"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148280314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2024 Joint Meeting of EEG and Clinical Neuroscience Society (ECNS), the International Society for Neuroimaging in Psychiatry (ISNIP), the International Society for Brain Electromagnetic Topography (ISBET), and the International Society for Functional Source Imaging (ISFSI).","authors":"","doi":"10.1177/15500594261448095","DOIUrl":"10.1177/15500594261448095","url":null,"abstract":"","PeriodicalId":93940,"journal":{"name":"Clinical EEG and neuroscience","volume":" ","pages":"NP1-NP10"},"PeriodicalIF":1.7,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148842258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}