Canadian journal of diabetes最新文献

{"title":"\"Managing Type 1 Diabetes During Marathons: A Case Study on Glucose Monitoring and Technology Failures\".","authors":"Denise Montt-Blanchard, Franco Giraudo, Raimundo Sánchez","doi":"10.1016/j.jcjd.2025.02.006","DOIUrl":"https://doi.org/10.1016/j.jcjd.2025.02.006","url":null,"abstract":"","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparing a New Generation of Providers in Canada: The Mental Health + Diabetes Training Program.","authors":"Tricia S Tang, Jessica C Kichler, Zosia R Anders, Marie Raffray, Tiffany R Shepherd, Brandi A Wicklow, Julia Bannister, Mona Gupta, Amanda M Hailman, Gerri M Klein, Joanne Lewis, Sarah E Linklater, Sadinand D Mankikar, Caleb Pope, Katie D Ryan, Remi Rabasa-Lhoret, Christine Tourigny, Michael Vallis","doi":"10.1016/j.jcjd.2025.02.007","DOIUrl":"10.1016/j.jcjd.2025.02.007","url":null,"abstract":"<p><p>Diabetes care in Canada is compromised by the lack of resources to adequately address the mental health challenges associated with both type 1 and type 2 diabetes. To address this gap Breakthrough T1D (formerly JDRF) Canada and Diabetes Canada developed a bilingual training program, and associated directory listing successful graduates, to educate and empower existing mental health providers to better provide services to those living with diabetes. This study reports on the development and initial outcomes of this virtual training program. Training involved 6 self-learning modules and a 3-hour interactive session to consolidate knowledge. Over a 24-month period, 796 mental health providers (68.5% English-speaking, 31.5% French-speaking) enrolled in the training program. Over half of enrollees (56.3%) have completed the program to date (N=448) and 37% of completers (N = 166) were approved for the Directory. The professions enrolled, spanning the country, included social workers (42.1%), psychologists (33.7%), psychotherapists (10.8%), counsellors (7.0%), mental health nurses (5.5%), and psychiatrists (0.6%). Satisfaction with the program was very high and training was considered very practical. The program is available at no cost on an ongoing basis, and follow-up research will evaluate the feasibility, acceptability, and potential health-related impact of training mental health providers in working with people with diabetes.</p>","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response.","authors":"Michael Vallis, Lori Berard, Emmanuel Cosson, Finn Boerlum Kristensen, Fleur Levrat-Guillen, Nicolas Naiditch, Remi Rabasa-Lhoret, William Polonsky","doi":"10.1016/j.jcjd.2025.02.005","DOIUrl":"10.1016/j.jcjd.2025.02.005","url":null,"abstract":"","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cannabis Hyperemesis Syndrome Can Mimic Diabetic Gastroparesis in Cannabis Users With Type 1 Diabetes.","authors":"Kagan E Karakus, Halis K Akturk","doi":"10.1016/j.jcjd.2025.02.004","DOIUrl":"10.1016/j.jcjd.2025.02.004","url":null,"abstract":"","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of Systemic Immune-Inflammation Index With Mortality Risk Among Adults in Diabetic Kidney Disease, NHANES 1999 to 2018.","authors":"Yun She, Xiangyun Guo, Ying Tan, Qingqing Liu, Lingling Zhu, Xiqiao Zhou, Jiangyi Yu, Qianhua Yan","doi":"10.1016/j.jcjd.2025.01.003","DOIUrl":"10.1016/j.jcjd.2025.01.003","url":null,"abstract":"<p><strong>Objectives: </strong>Immune-inflammation plays a crucial role in the pathogenesis of diabetic kidney disease (DKD), but an exact assessment of indicators remains undefined. In this study we address the link between systemic immune-inflammation index (SII) and mortality risk in DKD, and we explore the effect of sex disparities.</p><p><strong>Methods: </strong>Data from patients with DKD from the National Health and Nutritional Examination Surveys (NHANES, 1999 to 2018) were studied and their causes of death were identified from NHANES-related files. A weighted Cox model was used to evaluate hazard ratios for all-cause, cardiovascular, and cardiocerebrovascular mortality, and these associations were visualized by smoothing curves.</p><p><strong>Results: </strong>The average SII was 634.20 (10³/μL). There were 1,283 deaths recorded during 273,422 person months (396 were cardiovascular related and 461 were cardiocerebrovascular related). Higher SIIs in the fifth quintile were significantly associated with increased mortality (p<0.01). SII trends showed an increased risk of all-cause mortality of >697.0 (10³/μL), cardiovascular risk of >717.8 (10³/μL), and cardiocerebrovascular risk of >650.0 (10³/μL). In men, mortality increased when SII reached 500 to 660 (10³/μL) and 700 to 760 (10³/μL) for women.</p><p><strong>Conclusions: </strong>There was a significant association between higher SII and increased risk of all-cause, cardiovascular, and cardiocerebrovascular mortality in DKD patients. In addition, although men had lower SII, their mortality was higher than that of women.</p>","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What Is the Effectiveness of Type 2 Diabetes-related Patient Decision Aids? Secondary Analysis of a Systematic Review.","authors":"Sandhya Goge, Christopher Tran, Krystina B Lewis, Meg Carley, Carol Bennett, Dawn Stacey","doi":"10.1016/j.jcjd.2025.02.003","DOIUrl":"10.1016/j.jcjd.2025.02.003","url":null,"abstract":"<p><strong>Objectives: </strong>Patient decision aids (PtDAs) are evidence-based interventions to help people faced with difficult health-care decisions. Little is known about their effectiveness in people facing diabetes-related decisions. The aim of this study was to evaluate the scope and effectiveness of diabetes-related PtDAs for screening, prevention, and treatment decisions.</p><p><strong>Methods: </strong>Secondary analysis of randomized controlled studies (RCTs) from the 2024 Cochrane review of PtDAs comparing decisions aids on diabetes screening, prevention, or treatment to usual care (e.g. patient education, no intervention). Two reviewers independently screened citations, extracted data, and assessed study quality. Primary outcomes included quality of the decision and decision-making process. Meta-analyses were conducted for similar outcome measures.</p><p><strong>Results: </strong>Of the 209 RCTs, 11 eligible studies evaluated diabetes PtDAs for treatment (n=7), screening (n=3), and prevention (n=1). Common decisions were about diabetes treatment intensification (n=4) and statin initiation (n=3) in people with type 2 diabetes. Compared with usual care, the PtDA group reported increased knowledge (mean difference [MD] 16.06, 95% confidence interval [CI] 8.38 to 23.75) and clearer values (MD -7.43, 95% CI -13.23 to -1.63) and no difference in accurate risk perceptions. After removing high-risk-of-bias studies, PtDAs led to fewer patients feeling uninformed about their options (MD -6.38, 95% CI -9.58 to -3.19) and more participants starting new medications (relative risk ratio 1.65, 95% CI 1.06 to 2.56). Six studies measured adherence to a chosen option: 1 reported greater adherence, whereas another reported lower adherence in PtDA vs usual care and the remaining 4 reported no difference.</p><p><strong>Conclusions: </strong>Patients given PtDAs can improve their knowledge and feel informed and clearer about their values while being more likely to start new medications. Future research can strengthen the certainty of these findings and should explore PtDA use within the chronic disease context.</p>","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise Training for People With Diabetes-related Foot Ulcers---A Systematic Review of Glycemia, Fitness, and Wound-healing Outcomes.","authors":"Callum J Baker, Vivienne Chuter, Magali Brousseau-Foley, Danqing Min, Angela Searle, Stephen M Twigg, Nathan A Johnson","doi":"10.1016/j.jcjd.2025.02.002","DOIUrl":"10.1016/j.jcjd.2025.02.002","url":null,"abstract":"<p><strong>Objectives: </strong>Regular physical activity is a key, patient-centred therapy for people with diabetes to manage their glycemia. The International Working Group on the Diabetic Foot recommends optimization of glycemic control for people with/at risk of diabetes-related foot ulcer (DFU); however, people with DFU are commonly instructed by clinicians to avoid physical activity so as not to worsen the ulcer. The effects of exercise on glycemia, fitness, and wound healing in people with active DFU are not clear. In this study we examined the effects of regular exercise (training) on glycemia, cardiorespiratory fitness, muscular strength, metabolic health, and ulcer healing in adults with diabetes and an active foot ulcer.</p><p><strong>Methods: </strong>Online databases and reference lists of included studies were searched from earliest records to December 2023. Studies involving adult populations with DFU and incorporating interventions of exercise training were included. Data were extracted independently by 2 reviewers.</p><p><strong>Results: </strong>Of the 5,592 studies screened, 8 were included, with a total of 213 participants. Exercise interventions involved foot range-of-movement exercises and/or aerobic and/or resistance-type exercise. None of the studies reported on cardiorespiratory fitness or anthropometry and limited data were available for glycemic and muscular strength outcomes. Interpretation of data on safety, wound healing, and adherence to exercise were limited due to inconsistent reporting.</p><p><strong>Conclusions: </strong>Despite some data that exercise may have a positive impact on wound healing, evidence regarding its benefits and safety is significantly lacking, despite metabolic (particularly glycemic) and fitness outcomes being core to the rationale for exercise therapy in diabetes. Given the importance of exercise in current management guidelines for diabetes, and the plausibility of positive health effects of exercise training for people with DFU, there is a need for research to move from foot-focussed to person-centred outcomes to better inform the implementation of exercise therapy for people with DFU.</p>","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise and Glycemic Management in Females and Women With Diabetes: The Role of Sex and Gender Across the Lifespan.","authors":"Tricia M Peters, Anne-Sophie Brazeau, Lia Bally, Alexa Govette, Elsa Heyman, Mary E Jung, Céline I Laesser, Élodie Lespagnol, Jessica E Logan, Zeinab Momeni, Tawnya Perry, Meryem K Talbo, Anne Bonhoure, Jenna A P Sim, Jasmin von Zezschwitz, Dessi P Zaharieva, Jenna B Gillen, Jane E Yardley","doi":"10.1016/j.jcjd.2025.02.001","DOIUrl":"10.1016/j.jcjd.2025.02.001","url":null,"abstract":"<p><p>The benefits of exercise and physical activity (PA) for people living with diabetes are clear. However, current exercise recommendations do not take into consideration the potential impact of female-specific hormonal changes across the lifespan on the glycemic response to exercise. Moreover, the impact of life phases on barriers to participation in exercise and PA for women compared to men with diabetes is not well described. In this narrative review we have synthesized the literature to date regarding the interaction of female sex hormone variations (menarche and the menstrual cycle, pregnancy, and the menopausal transition) with glycemic management in the context of exercise for females with type 1 and type 2 diabetes. We also evaluated PA behaviours and barriers to participation in exercise and PA among individuals with diabetes identifying as women. We observed a lack of evidence regarding the impact of female-specific hormonal changes on the glycemic response to exercise among females with diabetes, with a particular paucity of studies during pregnancy and postpartum and for the menopausal transition. In this study we demonstrate that additional research is required to understand the influence of exercise on glucose management for females with diabetes across the lifespan, with the aim to provide safe and effective exercise recommendations and to encourage equitable participation in exercise and PA for females and women with diabetes throughout life.</p>","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Prevalence and Common Forms of Maturity-onset Diabetes of the Young in Greenland.","authors":"Anne Cathrine Baun Thuesen, Marie Balslev Backe, Genís Garcia-Erill, Mikkel Schubert, Kristian Ebbesen Hanghøj, Ida Moltke, Anders Albrechtsen, Niels Grarup, Anette Prior Gjesing, Marit Eika Jørgensen, Torben Hansen, Michael Lynge Pedersen","doi":"10.1016/j.jcjd.2025.01.002","DOIUrl":"10.1016/j.jcjd.2025.01.002","url":null,"abstract":"<p><strong>Objectives: </strong>Population studies have identified common genetic variants contributing substantially to the burden of diabetes in Greenland. However, the handling of suspected monogenic diabetes in diabetes clinics in Greenland has not been described. In this study we aimed to describe the referral rate, prevalence, and genetic causes of clinically identified monogenic diabetes in Greenland.</p><p><strong>Methods: </strong>All diabetes patients in Greenland referred for genetic testing due to suspected monogenic diabetes between 2014 and July 2022 were tallied. Targeted short read sequencing and Sanger sequencing of probands and their family members were used to screen for potentially deleterious variants in the maturity-onset diabetes of the young (MODY) genes GCK, HNF1A, HNF1B, and HNF4A. Clinical data were extracted from the electronic medical records and whole genome sequencing was performed for families with potentially deleterious variants for genetic ancestry analysis.</p><p><strong>Results: </strong>Between 2014 and July 2022, 58 probands were referred for genetic testing, equivalent to 0.1% of the population. Five variants were identified: GCK p.F133L, GCK p.D205E, HNF1A c.1108G>T, HNF1B p.Q182∗, HNF4A -178A>G. These variants were found in 11 probands and 19 family members, equivalent to a population prevalence of monogenic diabetes of 0.05%. Local ancestry analysis revealed that all the variants were found exclusively in Inuit haplotypes, despite all individuals being admixed with both Inuit and European genetic ancestry.</p><p><strong>Conclusions: </strong>The rate of referral and prevalence of monogenic diabetes is substantially higher in Greenland than in other populations and both rare and more common population-specific variants of Inuit genetic ancestry contribute to this high prevalence.</p>","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical Insights on Promoting Self-management in Adults With Type 2 Diabetes: Development and Validation of the Glucose Monitoring Impact Scale.","authors":"Saad Khan, Fatima Naveed, Ayesha Khan, Rizwan Ahmad, Faraz Arshad","doi":"10.1016/j.jcjd.2024.12.007","DOIUrl":"10.1016/j.jcjd.2024.12.007","url":null,"abstract":"","PeriodicalId":93918,"journal":{"name":"Canadian journal of diabetes","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}