Asian journal of andrology最新文献_第7页

Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA. 改善因无脑畸形而接受显微取精术（micro-TESE）的男性取精情况的技术。

Asian journal of andrology Pub Date : 2025-05-01 Epub Date: 2024-08-16 DOI: 10.4103/aja202450

Parviz K Kavoussi, Widi Atmoko, Germar-Michael Pinggera

引用次数: 0

Association of higher serum follicle-stimulating hormone levels with successful microdissection testicular sperm extraction outcomes in nonobstructive azoospermic men with reduced testicular volumes. 高血清促卵泡激素水平与睾丸体积减小的非阻塞性无精子症男性成功显微解剖睾丸精子提取结果的关系

Asian journal of andrology Pub Date : 2025-05-01 Epub Date: 2024-12-24 DOI: 10.4103/aja202493

Ming-Zhe Song, Li-Jun Ye, Wei-Qiang Xiao, Wen-Si Huang, Wu-Biao Wen, Shun Dai, Li-Yun Lai, Yue-Qin Peng, Tong-Hua Wu, Qing Sun, Yong Zeng, Jing Cai

{"title":"Association of higher serum follicle-stimulating hormone levels with successful microdissection testicular sperm extraction outcomes in nonobstructive azoospermic men with reduced testicular volumes.","authors":"Ming-Zhe Song, Li-Jun Ye, Wei-Qiang Xiao, Wen-Si Huang, Wu-Biao Wen, Shun Dai, Li-Yun Lai, Yue-Qin Peng, Tong-Hua Wu, Qing Sun, Yong Zeng, Jing Cai","doi":"10.4103/aja202493","DOIUrl":"10.4103/aja202493","url":null,"abstract":"Abstract: To investigate the impact of preoperative serum follicle-stimulating hormone (FSH) levels on the probability of testicular sperm retrieval, we conducted a study of nonobstructive azoospermic (NOA) men with different testicular volumes (TVs) who underwent microdissection testicular sperm extraction (micro-TESE). A total of 177 NOA patients undergoing micro-TESE for the first time from April 2019 to November 2022 in Shenzhen Zhongshan Obstetrics and Gynecology Hospital (formerly Shenzhen Zhongshan Urology Hospital, Shenzhen, China) were retrospectively reviewed. The subjects were divided into four groups based on average TV quartiles. Serum hormone levels in each TV group were compared between positive and negative sperm retrieval subgroups. Overall sperm retrieval rate was 57.6%. FSH levels (median [interquartile range]) were higher in the positive sperm retrieval subgroup compared with the negative outcome subgroup when average TV was <5 ml (first quartile [Q1: TV <3 ml]: 43.32 [17.92] IU l -1 vs 32.95 [18.56] IU l -1 , P = 0.048; second quartile [Q2: 3 ml ≤ TV <5 ml]: 31.31 [15.37] IU l -1 vs 25.59 [18.40] IU l -1 , P = 0.042). Elevated serum FSH levels were associated with successful micro-TESE sperm retrieval in NOA men whose average TVs were <5 ml (adjusted odds ratio [OR]: 1.06 per unit increase; 95% confidence interval [CI]: 1.01-1.11; P = 0.011). In men with TVs ≥5 ml, larger TVs were associated with lower odds of sperm retrieval (adjusted OR: 0.84 per 1 ml increase; 95% CI: 0.71-0.98; P = 0.029). In conclusion, elevated serum FSH levels were associated with positive sperm retrieval in micro-TESE in NOA men with TVs <5 ml. In men with TV ≥5 ml, increases in average TVs were associated with lower odds of sperm retrieval.","PeriodicalId":93889,"journal":{"name":"Asian journal of andrology","volume":" ","pages":"440-446"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12112938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonobstructive azoospermia: an etiologic review. 非梗阻性无精子症：病因综述。

Asian journal of andrology Pub Date : 2025-05-01 Epub Date: 2024-09-06 DOI: 10.4103/aja202472

Logan Hubbard, Amarnath Rambhatla, Sidney Glina

{"title":"Nonobstructive azoospermia: an etiologic review.","authors":"Logan Hubbard, Amarnath Rambhatla, Sidney Glina","doi":"10.4103/aja202472","DOIUrl":"10.4103/aja202472","url":null,"abstract":"Abstract: Azoospermia is the complete absence of spermatozoa in the ejaculate in two or more semen analyses after centrifugation. Nonobstructive azoospermia (NOA) represents the most severe form of male factor infertility accounting for 10%-15% of cases and stems from an impairment to spermatogenesis. Understanding of the hypothalamic-pituitary-testicular axis has allowed NOA to be subcategorized by anatomic and/or pathophysiologic level. The etiologies of NOA, and therefore, the differential diagnoses when considering NOA as a cause of male factor infertility, can be subcategorized and condensed into several distinct classifications. Etiologies of NOA include primary hypogonadism, secondary hypogonadism, defects in androgen synthesis and/or response, defective spermatogenesis and sperm maturation, or a mixed picture thereof. This review includes up-to-date clinical, diagnostic, cellular, and histologic features pertaining to the multitude of NOA etiologies. This in turn will provide a framework by which physicians practicing infertility can augment their clinical decision-making, patient counseling, thereby improving upon the management of men with NOA.","PeriodicalId":93889,"journal":{"name":"Asian journal of andrology","volume":" ","pages":"279-287"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12112933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142147064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occlusive effectiveness of open-ended no-scalpel vasectomy with mucosal cautery and fascial interposition: a descriptive study. 开放式无刀输精管结扎术粘膜烧烂和筋膜介入的闭塞效果：一项描述性研究。

Asian journal of andrology Pub Date : 2025-04-25 DOI: 10.4103/aja202517

Souleymane Diabate, Marco Arellano, Jonathan Cloutier, Michel Dallaire, Simon Plourde, Michel Labrecque

{"title":"Occlusive effectiveness of open-ended no-scalpel vasectomy with mucosal cautery and fascial interposition: a descriptive study.","authors":"Souleymane Diabate, Marco Arellano, Jonathan Cloutier, Michel Dallaire, Simon Plourde, Michel Labrecque","doi":"10.4103/aja202517","DOIUrl":"https://doi.org/10.4103/aja202517","url":null,"abstract":"Abstract: We aimed to assess the occlusive effectiveness of open-ended vasectomy with mucosal cautery and fascial interposition and to determine the factors associated with occlusion failure. We studied all vasectomies performed between September 1, 2020, and August 31, 2021, by four vasectomy surgeons from Quebec City, Quebec, Canada. Sociodemographic and clinical characteristics were extracted from the electronic medical records. Occlusive effectiveness was assessed in all men with at least one postvasectomy semen analysis (PVSA). The effectiveness criteria were adapted from those of the American Urological Association (AUA) vasectomy guideline. Among the 4000 eligible vasectomies, 2242 (56.1%) were followed by at least one PVSA, with 99 (4.4%) requiring more than one PVSA. Occlusive effectiveness was achieved in 2233 vasectomies (99.6%; 95% confidence interval [CI]: 99.3%-99.8%), with 2199 (98.1%) and 34 (1.5%) classified as confirmed and probable success, respectively. The final status of the three vasectomies (0.1%) was indeterminate. Occlusive failure was observed in six vasectomies (0.3%; 95% CI: 0.1%-0.6%). The four surgeons had a similar risk of failure. The only significant factor associated with failure was the difficulty in performing the vas occlusion reported by the surgeon (7.4% [2/27] vs 0.2% [4/2212]; relative risk = 41.0; 95% CI: 7.8-214.2). The high occlusive effectiveness observed in our study validates AUA recommendations, supporting the use of this technique. Difficulty in occlusion of the vas deferens, as reported by surgeons, was the only factor associated with vasectomy failure. This finding highlights the need for PVSA in such cases.","PeriodicalId":93889,"journal":{"name":"Asian journal of andrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in the management of male infertility. 男性不育治疗的最新进展。

Asian journal of andrology Pub Date : 2025-04-25 DOI: 10.4103/aja20257

Rashed Rowaiee, Omar Almidani, Omer A Raheem

引用次数: 0

Sexual activity in men undergoing ADT for localized prostate cancer: a narrative literature review. 局限性前列腺癌接受ADT治疗的男性的性活动：一篇叙述性文献综述。

Asian journal of andrology Pub Date : 2025-04-25 DOI: 10.4103/aja20253

Laeticia Creidy, Daniel Taussky, Frederic Pouliot, Fred Saad, Fabian Falkenbach

{"title":"Sexual activity in men undergoing ADT for localized prostate cancer: a narrative literature review.","authors":"Laeticia Creidy, Daniel Taussky, Frederic Pouliot, Fred Saad, Fabian Falkenbach","doi":"10.4103/aja20253","DOIUrl":"https://doi.org/10.4103/aja20253","url":null,"abstract":"Abstract: Androgen deprivation therapy (ADT) can negatively affect sexual function, and only a minority of patients report sexual activity. We reviewed the existing literature regarding the proportion of men who remained sexually active during and after ADT. The PubMed database was searched for studies published over the past 20 years. We selected and reviewed randomized clinical trials that provided sexual function data at baseline and during and after ADT. The primary outcome measure was the sexual function. Studies assessed sexual function using quality of life patient-reported outcome measures, which included sexual potency/activity evaluation. Information from 2947 patients was analyzed in this review. The median age of patients was 70 years. At baseline, a median of 49.9% (95% confidence interval [CI]: 49.1%-50.7%) of the patients reported being sexually active. At 6 months, 12 months, and 2 years or later of ADT treatment, a median of 10.3% (95% CI: 10.2%-10.5%), 8.9% (95% CI: 8.6%-9.2%), and 8.3% (95% CI: 8.2%-8.5%) of the patients reported being sexually active, respectively. Considering that half of the patients were sexually active at baseline, it seems probable that more than 10% of the patients who were sexually active before starting ADT remained sexually active when undergoing ADT. In conclusion, despite the common belief that ADT eliminates sexual activity, this analysis found that approximately 1 in 10 men are sexually active when on ADT, and this proportion is likely increased in men who are sexually active before starting ADT. Attention to sexual activity should not be dismissed in men on ADT.","PeriodicalId":93889,"journal":{"name":"Asian journal of andrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microfluidic systems in testicular in vitro culture: a powerful model tool for spermatogenesis and reprotoxicity studies. 睾丸体外培养中的微流体系统：精子发生和生殖毒性研究的强大模型工具。

Asian journal of andrology Pub Date : 2025-04-22 DOI: 10.4103/aja20254

Botho Maximilian Schneider, Hande Irem Hamurcu, Andrea Salzbrunn, Kathrein von Kopylow

{"title":"Microfluidic systems in testicular in vitro culture: a powerful model tool for spermatogenesis and reprotoxicity studies.","authors":"Botho Maximilian Schneider, Hande Irem Hamurcu, Andrea Salzbrunn, Kathrein von Kopylow","doi":"10.4103/aja20254","DOIUrl":"https://doi.org/10.4103/aja20254","url":null,"abstract":"Abstract: As prepubertal boys do not yet produce spermatozoa, they cannot rely on sperm cryopreservation for fertility preservation before gonadotoxic therapy, such as high-dose alkylating agents or radiotherapy in the case of childhood cancers. According to the current guidelines, cryopreservation of testicular biopsies containing spermatogonial stem cells (SSCs) may be proposed to high-risk patients for potential later therapeutic use to fulfill the patients' wish for a biological child. One promising technique for human in vitro spermatogenesis and in vitro propagation of human SSCs is microfluidic (MF) culture, in which cells or tissues are subjected to a continuous flow of medium. This provides exact control over such parameters as nutrient content and gradients, as well as the removal of waste metabolites. While MF has been shown to maintain tissues and cell populations of organs for longer than conventional in vitro culture techniques, it has not been widely used for testicular in vitro culture. MF could advance human testicular in vitro culture and is also applicable to reprotoxicity studies. This review summarizes the findings and achievements of testis-on-chip (ToC) setups to date and discusses the benefits and limitations of these for spermatogenesis in vitro and toxicity assessment.","PeriodicalId":93889,"journal":{"name":"Asian journal of andrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exogenous administration of heparin-binding epidermal growth factor-like growth factor improves erectile function in mice with bilateral cavernous nerve injury. 外源性肝素结合表皮生长因子样生长因子可改善双侧海绵状神经损伤小鼠的勃起功能。

Asian journal of andrology Pub Date : 2025-04-18 DOI: 10.4103/aja2024125

Minh Nhat Vo, Mi-Hye Kwon, Fang-Yuan Liu, Fitri Rahma Fridayana, Yan Huang, Soon-Sun Hong, Ju-Hee Kang, Guo Nan Yin, Ji-Kan Ryu

{"title":"Exogenous administration of heparin-binding epidermal growth factor-like growth factor improves erectile function in mice with bilateral cavernous nerve injury.","authors":"Minh Nhat Vo, Mi-Hye Kwon, Fang-Yuan Liu, Fitri Rahma Fridayana, Yan Huang, Soon-Sun Hong, Ju-Hee Kang, Guo Nan Yin, Ji-Kan Ryu","doi":"10.4103/aja2024125","DOIUrl":"https://doi.org/10.4103/aja2024125","url":null,"abstract":"Prostate cancer is the second most common malignancy and the sixth leading cause of cancer-related death in men worldwide. Radical prostatectomy (RP) is the standard treatment for localized prostate cancer, but the procedure often results in postoperative erectile dysfunction (ED). The poor efficacy of phosphodiesterase 5 inhibitors after surgery highlights the need to develop new therapies to enhance cavernous nerve regeneration and improve the erectile function of these patients. In the present study, we aimed to examine the potential of heparin-binding epidermal growth factor-like growth factor (HB-EGF) in preserving erectile function in cavernous nerve injury (CNI) mice. We found that HB-EGF expression was reduced significantly on the 1st day after CNI in penile tissue. Ex vivo and in vitro studies showed that HB-EGF promotes major pelvic ganglion neurite sprouting and neuro-2a (N2a) cell migration. In vivo studies showed that exogenous HB-EGF treatment significantly restored the erectile function of CNI mice to 86.9% of sham levels. Immunofluorescence staining showed that mural and neuronal cells were preserved by inducing cell proliferation and reducing apoptosis and reactive oxygen species production. Western blot analysis showed that HB-EGF upregulated protein kinase B and extracellular signal-regulated kinase activation and neurotrophic factor expression. Overall, HB-EGF is a major promising therapeutic agent for treating ED in postoperative RP.","PeriodicalId":93889,"journal":{"name":"Asian journal of andrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in penile lengthening techniques concurrent with penile prosthesis placement: a narrative review. 阴茎延长技术与阴茎假体放置的进展：叙述回顾。

Asian journal of andrology Pub Date : 2025-04-18 DOI: 10.4103/aja202512

Mattia Lo Re, Manuel Alonso Isa, Esther Garcia Rojo, Celeste Manfredi, Agustin Fraile Poblador, Marta Pezzoli, Andrea Cocci, Francesco Sessa, Andrea Minervini, Javier Romero-Otero

{"title":"Advancements in penile lengthening techniques concurrent with penile prosthesis placement: a narrative review.","authors":"Mattia Lo Re, Manuel Alonso Isa, Esther Garcia Rojo, Celeste Manfredi, Agustin Fraile Poblador, Marta Pezzoli, Andrea Cocci, Francesco Sessa, Andrea Minervini, Javier Romero-Otero","doi":"10.4103/aja202512","DOIUrl":"https://doi.org/10.4103/aja202512","url":null,"abstract":"Penile prosthetic devices stand as the foremost solution for medication-resistant erectile dysfunction. Frequently, medical conditions triggering erectile dysfunction also led to penile shortening, detrimentally impacting patients' quality of life. This narrative review aims to explore and evaluate the various techniques available for penile lengthening that can be performed concurrently with inflatable penile prosthesis (IPP) insertion. We conducted a comprehensive examination of the literature, utilizing PubMed focusing on key terms such as \"penile prosthesis corporal length\", \"inflatable penile prosthesis and short penis\", and \"buried penis\". The review identified several advanced methodologies for preserving and enhancing penile length during IPP insertion. These techniques include subcoronal IPP insertion, sliding technique, modified sliding technique, multiple slice technique, and circumferential incision with grafting. Supplementary procedures aimed at improving the perception of increased length involve ventral phalloplasty and suprapubic lipectomy. It is worth noting that the maximum length gain seems to be constrained by the length of the neurovascular bundles. In summary, the evidence available in the literature is limited due to the short of case series reported, lack of randomized controlled trials, and heterogeneity of the studies. The literature suggests that for carefully selected patients, surgical penile lengthening procedures performed concurrently with IPP insertion emerge as effective treatments for individuals grappling with penile shortening and severe erectile dysfunction. Well-designed, larger studies are needed to establish the safety and efficacy of these procedures.","PeriodicalId":93889,"journal":{"name":"Asian journal of andrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent spontaneous miscarriages from sperm after ABVD chemotherapy in a patient with Hodgkin's lymphoma: sperm DNA and methylation profiling. 霍奇金淋巴瘤患者ABVD化疗后精子复发性自发流产：精子DNA和甲基化分析

Asian journal of andrology Pub Date : 2025-04-15 DOI: 10.4103/aja2024107

Gwendoline Lecuyer, Antoine D Rolland, Anne-Sophie Neyroud, Bertrand Evrard, Nathan Alary, Clemence Genthon, Nathalie Dejucq-Rainsford, Célia Ravel, Jessika Moreau, Nathalie Moinard, Mohamed Hadi Mohamed Abdelhamid, Christophe Klopp, Louis Bujan, Frédéric Chalmel

{"title":"Recurrent spontaneous miscarriages from sperm after ABVD chemotherapy in a patient with Hodgkin's lymphoma: sperm DNA and methylation profiling.","authors":"Gwendoline Lecuyer, Antoine D Rolland, Anne-Sophie Neyroud, Bertrand Evrard, Nathan Alary, Clemence Genthon, Nathalie Dejucq-Rainsford, Célia Ravel, Jessika Moreau, Nathalie Moinard, Mohamed Hadi Mohamed Abdelhamid, Christophe Klopp, Louis Bujan, Frédéric Chalmel","doi":"10.4103/aja2024107","DOIUrl":"https://doi.org/10.4103/aja2024107","url":null,"abstract":"Abstract: Lymphomas represent one of the most common malignant diseases in young men and an important issue is how treatments will affect their reproductive health. It has been hypothesized that chemotherapies, similarly to environmental chemicals, may alter the spermatogenic epigenome. Here, we report the genomic and epigenomic profiling of the sperm DNA from a 31-year-old Hodgkin lymphoma patient who faced recurrent spontaneous miscarriages in his couple 11-26 months after receiving chemotherapy with adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD). In order to capture the potential deleterious impact of the ABVD treatment on mutational and methylation changes, we compared sperm DNA before and 26 months after chemotherapy with whole-genome sequencing (WGS) and reduced representation bisulfite sequencing (RRBS). The WGS analysis identified 403 variants following ABVD treatment, including 28 linked to genes crucial for embryogenesis. However, none were found in coding regions, indicating no impact of chemotherapy on protein function. The RRBS analysis identified 99 high-quality differentially methylated regions (hqDMRs) for which methylation status changed upon chemotherapy. Those hqDRMs were associated with 87 differentially methylated genes, among which 14 are known to be important or expressed during embryo development. While no variants were detected in coding regions, promoter regions of several genes potentially important for embryo development contained variants or displayed an altered methylated status. These might in turn modify the corresponding gene expression and thus affect their function during key stages of embryogenesis, leading to potential developmental disorders or miscarriages.","PeriodicalId":93889,"journal":{"name":"Asian journal of andrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0