{"title":"Cardiac Implantable Electronic Devices in Chagasic and Non-Chagasic Patients: A Critical Look at the Prognosis.","authors":"Fernanda Almeida Andrade","doi":"10.36660/abc.20240629","DOIUrl":"10.36660/abc.20240629","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240629"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial Intelligence Methods for Detecting Asymptomatic Atrial Fibrillation. An Opportunity for New Prevention Approaches and the Role of the Doctor's Eye.","authors":"Francisco Darrieux, Tan Chen Wu","doi":"10.36660/abc.20240662","DOIUrl":"10.36660/abc.20240662","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240662"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcelo de Paula Martins Monteiro, Helena Nogueira Brasil, Carlos Roberto Martins Rodrigues Sobrinho, Eduardo Arrais Rocha
{"title":"Is it Fair to Contraindicate Cardiac Defibrillator Implantation for Patients with Socioeconomic or Psychological Vulnerability?","authors":"Marcelo de Paula Martins Monteiro, Helena Nogueira Brasil, Carlos Roberto Martins Rodrigues Sobrinho, Eduardo Arrais Rocha","doi":"10.36660/abc.20240643","DOIUrl":"10.36660/abc.20240643","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240643"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
João Marcos Bemfica Barbosa Ferreira, Maria Helena Costa de Vasconcelos, Andreza Araújo de Oliveira, Maria Eduarda da Silva Corrêa
{"title":"Impact of Technological Innovation in the Treatment and Prognosis of Heart Failure.","authors":"João Marcos Bemfica Barbosa Ferreira, Maria Helena Costa de Vasconcelos, Andreza Araújo de Oliveira, Maria Eduarda da Silva Corrêa","doi":"10.36660/abc.20240680","DOIUrl":"10.36660/abc.20240680","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240680"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dhayn Cassi de Almeida Freitas, Larissa Maria de Paula Rebouças da Costa, Wilson Nadruz, Fabiana G Marcondes-Braga, Jefferson Luis Vieira, Sabrina Bernardez-Pereira, Wilson Rodrigues Barbosa Neto, Silvia Marinho Martins Alves, Gabriela Arcoverde Wanderley, Camila Nogueira Leandro Lira, Lucas Yugi de Souza Terui, Ana Luísa Guedes de França E Silva, Alana de Oliveira Castro, Aguinaldo F Freitas, José Albuquerque de Figueiredo Neto, Renato D Lopes, Miguel Morita Fernandes-Silva, Odilson Marcos Silvestre
{"title":"Rosa dos Ventos Multicenter Cohort Study of Patients with Reduced or Mildly Reduced Ejection Fraction Heart Failure in Brazil: Rationale and Design.","authors":"Dhayn Cassi de Almeida Freitas, Larissa Maria de Paula Rebouças da Costa, Wilson Nadruz, Fabiana G Marcondes-Braga, Jefferson Luis Vieira, Sabrina Bernardez-Pereira, Wilson Rodrigues Barbosa Neto, Silvia Marinho Martins Alves, Gabriela Arcoverde Wanderley, Camila Nogueira Leandro Lira, Lucas Yugi de Souza Terui, Ana Luísa Guedes de França E Silva, Alana de Oliveira Castro, Aguinaldo F Freitas, José Albuquerque de Figueiredo Neto, Renato D Lopes, Miguel Morita Fernandes-Silva, Odilson Marcos Silvestre","doi":"10.36660/abc.20240120","DOIUrl":"10.36660/abc.20240120","url":null,"abstract":"<p><strong>Background: </strong>Brazil is a country with different biomes and social disparities. There are limited data available on regional differences and prognosis of heart failure (HF) in the country.</p><p><strong>Objective: </strong>The Rosa dos Ventos study aims to investigate regional differences and the current prognosis of HF outpatients with reduced or mildly reduced ejection fraction in Brazil.</p><p><strong>Methods: </strong>This is a prospective, multicenter, observational cohort study that will include outpatients older than 18 years with HF and an ejection fraction < 50% in 30 public and private centers distributed in all Brazilian regions. A total of 2,500 patients will be enrolled from June 2021 and October 2023, with a 12-month follow-up period. We will collect data on socioeconomic and clinical status, medical prescription and results of cardiology tests. Follow-up phone calls will be made at 6 and 12 months after inclusion to collect information regarding emergency room visits, hospitalization and mortality.</p><p><strong>Conclusion: </strong>The Rosa dos Ventos study will allow a more accurate characterization of chronic HF in Brazil. This initiative will provide relevant information for the development of effective management strategies to mitigate the impact of this condition on patients and the healthcare system.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240120"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Osteoprotegerin: A Biomarker in Chronic Kidney Disease.","authors":"Rui Póvoa","doi":"10.36660/abc.20240679","DOIUrl":"10.36660/abc.20240679","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 11","pages":"e20240679"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Filipe Ferrari, Arthur Proença Rossi, Igor Rafael Miranda Ferreira Santander
{"title":"Heart Failure in Brazil: How Can We Improve its Natural History?","authors":"Filipe Ferrari, Arthur Proença Rossi, Igor Rafael Miranda Ferreira Santander","doi":"10.36660/abc.20240644","DOIUrl":"10.36660/abc.20240644","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240644"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Women and Atrial Fibrillation: Is the Disparity in Anticoagulation Just a Question of Gender? In Search of the Brazilian Reality.","authors":"Jorge Elias Neto, Fernando Luiz Torres Gomes","doi":"10.36660/abc.20240583","DOIUrl":"10.36660/abc.20240583","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240583"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of Serum Glycogen Synthase 3 Beta Levels in Patients with Heart Failure, a Novel Marker for Diagnosis and Defining Disease Severity?","authors":"Gokhan Altunbas, Mehmet Kaplan, Veysel Duzen, Emin Erdem Kaya, Hafize Gokce Gokdeniz, Seyithan Taysi","doi":"10.36660/abc.20240155","DOIUrl":"10.36660/abc.20240155","url":null,"abstract":"<p><strong>Background: </strong>Glycogen synthase kinase 3β (GSK3β) is an enzyme that has roles in the pathogenesis of heart failure (HF). We try to reveal serum GSK3β levels in types of HF.</p><p><strong>Objectives: </strong>In this study, we evaluated serum GSK3β levels in HF patients. Also, we tried to elucidate any possible relationship between serum GSK3β levels and disease severity among three different types of HF patients.</p><p><strong>Methods: </strong>We performed a prospective study and enrolled 112 patients: 50 patients in heart failure with preserved ejection fraction (HFpEF) group, 30 patients in heart failure with mildly reduced ejection fraction (HFmrEF) group, and 32 patients in heart failure with reduced ejection fraction group (HFrEF). We also evaluated 50 healthy controls. Echocardiographic examinations were performed. We measured serum GSK-3β and N-terminal pro-B-type natriuretic peptide (NT-proBNP). We measured highly sensitive C-reactive protein (hs-CRP) levels and calculated neutrophil-lymphocyte ratio (NLR) platelets-to-lymphocyte ratio (PLR) from the hemogram count. Statistical significance was accepted p < 0.05.</p><p><strong>Results: </strong>Serum GSK3β levels were significantly higher among patients with HF compared to healthy controls (median GSK3β levels; 117.26 (45.39 -223.85) vs 13.91 (5.6 -23.3) ng/mL, p<0.001). Also, GSK3β levels were highest among patients with HFpEF and lowest among patients with HFrEF; 236.44 (132.89 -432) vs. 38.72 (23.15-67.31) ng/mL respectively (p<0.001). Median NT-proBNP levels, as expected, were significantly higher among patients with HF compared to healthy controls (660 (291 -1000) vs. 92 (78 -102) pg/mL, p<0.001). As a marker of systemic inflammation, hsCRP values, NLR, and PLR did not differ significantly among HF patients and controls.</p><p><strong>Conclusion: </strong>GSK3β levels were significantly higher among patients with HF. Also, as the ejection fraction declines, GSK3β levels also reduce, probably as a protective mechanism to prevent further apoptosis and myocyte death.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 11","pages":"e20240155"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}