Arquivos brasileiros de cardiologia最新文献

{"title":"Electrocardiogram as a Predictor of Mortality in Individuals with Pulmonary Hypertension.","authors":"Frederico José Neves Mancuso","doi":"10.36660/abc.20240548","DOIUrl":"10.36660/abc.20240548","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240548"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Hundred Years of the Nobel Prize for Electrocardiography: A Technology Still Essential and Fit for the Next Century.","authors":"Eduardo M Vilela, Nuno Bettencourt","doi":"10.36660/abc.20240494","DOIUrl":"https://doi.org/10.36660/abc.20240494","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240494"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fondaparinux versus Enoxaparin in the Treatment of Obese Patients with Acute Coronary Syndrome.","authors":"Beatriz Rocha Darzé, Carolina Costa da Silva Souza, Queila Borges de Oliveira, João Victor Santos Pereira Ramos, Mateus S Viana, Eduardo Sahade Darzé, Luiz Eduardo Fonteles Ritt","doi":"10.36660/abc.20230793","DOIUrl":"10.36660/abc.20230793","url":null,"abstract":"<p><strong>Background: </strong>Fondaparinux is an effective and safe anticoagulant in the treatment of acute coronary syndromes (ACS). However, due to the low representation of obese individuals in clinical trials, the effects of applying the results of this drug to this population remain uncertain.</p><p><strong>Objectives: </strong>To compare Fondaparinux to Enoxaparin in the treatment of obese patients with ACS.</p><p><strong>Methods: </strong>This is a retrospective cohort study, including obese individuals (BMI ≥ 30 Kg/m2) admitted with non-ST-segment elevation myocardial infarction (NSTEMI) or unstable angina (UA) and treated with Fondaparinux or Enoxaparin between 2010 and 2020. The Fondaparinux and Enoxaparin groups were compared for their clinical and laboratory characteristics using chi-square and Mann-Whitney tests, as appropriate. The incidence of primary outcomes (death, reinfarction, stroke, major bleeding) was compared between groups. P-value < 0.05 was considered significant for all analyses.</p><p><strong>Results: </strong>A total of 367 obese patients with NSTEMI or UA were included, of whom 258 used Fondaparinux and 109 used Enoxaparin. Mean age was 64 ± 12 years, and 52.9% were male. The prevalence of diabetes, hypertension, dyslipidemia, prior coronary artery disease, prior stroke, and implementation of invasive strategy was similar between groups. The incidence of the primary outcome was 4.7% in the Fondaparinux group and 5.5% in the Enoxaparin group (p = 0.729). There was no difference between groups when analyzing the components of the primary outcome separately.</p><p><strong>Conclusion: </strong>In a sample of obese patients with NSTEMI or UA, there was no difference in the occurrence of the composite outcome (death, stroke, reinfarction, major bleeding) between patients who used Fondaparinux or Enoxaparin.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20230793"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced Heart Failure and Onset of New Prognostic Markers: Where are We?","authors":"Meliza Goi Roscani","doi":"10.36660/abc.20240453","DOIUrl":"10.36660/abc.20240453","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240453"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Constellation of Stroke and Hypoxemia Post ICD Lead Extraction: Role of Patent Foramen Ovale.","authors":"Ashish H Shah, Petra Jenkins, Heiko Schneider","doi":"10.36660/abc.20240303","DOIUrl":"10.36660/abc.20240303","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240303"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brazilian Guideline for Exercise Testing in Children and Adolescents - 2024.","authors":"Tales de Carvalho, Odilon Gariglio Alvarenga de Freitas, William Azem Chalela, Carlos Alberto Cordeiro Hossri, Mauricio Milani, Susimeire Buglia, Andréa Maria Gomes Marinho Falcão, Ricardo Vivacqua Cardoso Costa, Luiz Eduardo Fonteles Ritt, Maria Eulália Thebit Pfeiffer, Odwaldo Barbosa E Silva, Rodrigo Imada, José Luiz Barros Pena, Antônio Carlos Avanza Júnior, Carlos Alberto Cyrillo Sellera","doi":"10.36660/abc.20240525","DOIUrl":"10.36660/abc.20240525","url":null,"abstract":"<p><strong>Classes of recommendation: </strong></p><p><strong>Levels of evidence: </strong></p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240525"},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smartwatch for Identification of Atrioventricular Block in Post-cardiac Surgery: Going Beyond Atrial Fibrillation Detection.","authors":"Matheus S Moitinho, Camila R Moreno, Rosangela Monteiro, Guilherme C M Rabello, Bruna M Mariano, Pietro C C O Martins, Flávio Tarasoutchi, Nelson Samesima, Alexandre de M Soeiro, Fabio B Jatene","doi":"10.36660/abc.20240131","DOIUrl":"10.36660/abc.20240131","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240131"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11516154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise Training Reduces Inflammation and Fibrosis and Preserves Myocardial Function and Perfusion in a Model of Chronic Chagas Cardiomyopathy.","authors":"Thayrine R Damasceno, Denise M Tanaka, Enrico F Magnani, Rafael D B Oliveira, Danielle A G Pereira, Ildernandes Vieira-Alves, Virginia S Lemos, Jorge M Cabeza, Camila G Fabricio, Alessandra A Resende, Dawit A P Gonçalves, Gustavo de Oliveira Zanetti, Eduardo E Vieira de Carvalho, Marcus V Simões, Luciano F L Oliveira","doi":"10.36660/abc.20230707","DOIUrl":"10.36660/abc.20230707","url":null,"abstract":"<p><strong>Background: </strong>Chronic Chagas cardiomyopathy (CCC) is caused by an inflammatory process induced by Trypanosoma cruzi, which leads to myocarditis with reactive and reparative fibrosis. CCC progresses with myocardial perfusion abnormalities and histopathological events that affect cardiorespiratory fitness (CRF).</p><p><strong>Objectives: </strong>We evaluated the effects of aerobic physical training (APT) on myocardial perfusion and on morphological and functional impairments related with inflammation and fibrosis in Syrian hamsters with CCC. As a secondary objective, we analyzed the cross-sectional areas of the skeletal muscle.</p><p><strong>Methods: </strong>Hamsters with CCC and their respective controls were divided into four groups: CCC sedentary, CCC-APT, sedentary control and APT control. Seven months after infection, the animals underwent echocardiography, myocardial perfusion scintigraphy and cardiopulmonary exercise testing. Moderate-intensity APT was performed for fifty minutes, five times a week, for eight weeks. Subsequently, the animals were reassessed. Histopathological analysis was conducted after the above-mentioned procedures. The level of significance was set at 5% in all analyses (p<0.05).</p><p><strong>Results: </strong>CCC sedentary animals presented worse myocardial perfusion defects (MPD) over time, reduced left ventricle ejection fraction (LVEF) and showed more inflammation and fibrosis when compared to other groups (mixed ANOVA analysis). Conversely, APT was able to mitigate the progression of MPD, ameliorate inflammation and fibrosis and improve CRF efficiency in CCC-APT animals.</p><p><strong>Conclusions: </strong>Our study demonstrated that APT ameliorated cardiac dysfunction, MPD, and reduced inflammation and fibrosis in CCC hamster models. Additionally, CCC-SED animals presented skeletal muscle atrophy while CCC-APT animals showed preserved skeletal muscle CSA. Understanding APT's effects on CCC's pathophysiological dimensions is crucial for future research and therapeutic interventions.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20230707"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Duration and the Risk of Atherosclerosis: A Mendelian Randomization Study.","authors":"Xiaozhuo Xu, Yilin Huang, Jing Liu, Xu Han","doi":"10.36660/abc.20230813","DOIUrl":"10.36660/abc.20230813","url":null,"abstract":"<p><strong>Background: </strong>The association between the length of sleep and atherosclerosis has been reported in many observational studies. However, little is known about its significance as a risk factor for atherosclerosis or as a negative consequence of atherosclerosis.</p><p><strong>Objective: </strong>This study aimed to assess the causal association between sleep duration and the risk of atherosclerosis using publicly available genome-wide association studies (GWAS) summary statistics.</p><p><strong>Methods: </strong>We employed a two-sample Mendelian randomization (MR) method with 2 cohorts from MRC-IEU (n=460,099) and UK Biobank (n=361,194) to investigate the causal association between sleep duration and the risk of atherosclerosis. Three methods including the inverse-variance weighted (IVW) technique, Robust adjusted profile score (RAPS), and simple-and weighted-median approach were used to obtain reliable results, and an odds ratio with a 95% confidence interval (CI) was calculated. P<0.05 was considered as a statistical difference. In addition, MR-Egger regression, Radial MR, MR-PRESSO, and leave-one-out analyses were used to assess the possible pleiotropy effects.</p><p><strong>Results: </strong>No causal association of sleep duration with atherosclerosis was found [OR (95%CI): 0.90 (0.98-1.00), p = 0.186]. Leave-one-out, MR-Egger, and MR-PRESSO analyses failed to detect horizontal pleiotropy.</p><p><strong>Conclusions: </strong>This MR analysis indicated no causal association between genetically predicted sleep duration and atherosclerosis across European populations.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240813"},"PeriodicalIF":0.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of 30-Day Hospital Readmission Following CABG in a Multicenter Database: A Cross-Sectional Study.","authors":"Rene Augusto Gonçalves E Silva, Gabrielle Barbosa Borgomoni, Fabiane Letícia de Freitas, Adnaldo da Silveira Maia, Cleóstones Farias do Vale Junior, Eva da Silva Pereira, Leonardy Guilherme Ibrahim Silvestre, Luís Roberto Palma Dallan, Luiz Augusto Lisboa, Luís Alberto Oliveira Dallan, Fabio Biscegli Jatene, Omar Asdrúbal Vilca Mejia","doi":"10.36660/abc.20230768","DOIUrl":"10.36660/abc.20230768","url":null,"abstract":"<p><strong>Background: </strong>The analysis of indicators such as hospital readmission rates is crucial for improving the quality of services and management of hospital processes.</p><p><strong>Objectives: </strong>To identify the variables correlated with hospital readmission up to 30 days following coronary artery bypass grafting (CABG).</p><p><strong>Methods: </strong>Cross-sectional cohort study by REPLICCAR II database (N=3,392) from June 2017 to June 2019. Retrospectively, 150 patients were analyzed to identify factors associated with hospital readmission within 30 days post-CABG using univariate and multivariate logistic regression. Analysis was conducted using software R, with a significance level of 0.05 and 95% confidence intervals.</p><p><strong>Results: </strong>Out of 3,392 patients, 150 (4,42%0 were readmitted within 30 days post-discharge from CABG primarily due to infections (mediastinitis, surgical wounds, and sepsis) accounting for 52 cases (34.66%). Other causes included surgical complications (14/150, 9.33%) and pneumonia (13/150, 8.66%). The multivariate regression model identified an intercept (OR: 1.098, p<0.00001), sleep apnea (OR: 1.117, p=0.0165), cardiac arrhythmia (OR: 1.040, p=0.0712), and intra-aortic balloon pump use (OR: 1.068, p=0.0021) as predictors of the outcome, with an AUC of 0.70.</p><p><strong>Conclusion: </strong>4.42% of patients were readmitted post-CABG, mainly due to infections. Factors such as sleep apnea (OR: 1.117, p=0.0165), cardiac arrhythmia (OR: 1.040, p=0.0712), and intra-aortic balloon pump use (OR: 1.068, p=0.0021) were predictors of readmission, with moderate risk discrimination (AUC: 0.70).</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20230768"},"PeriodicalIF":0.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}