Arquivos brasileiros de cardiologia最新文献

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Lyme Carditis: An Infectious Cause of Atrioventricular Block - A Case Report. 莱姆心肌炎:感染性房室传导阻滞--病例报告。
Arquivos brasileiros de cardiologia Pub Date : 2024-11-15 eCollection Date: 2024-01-01 DOI: 10.36660/abc.20240301
Eduardo Dan Itaya, Danilo Hantschick Fernandes Monteiro, Gabriela Coelho Itaya, Nathan Kong, Andre d'Avila
{"title":"Lyme Carditis: An Infectious Cause of Atrioventricular Block - A Case Report.","authors":"Eduardo Dan Itaya, Danilo Hantschick Fernandes Monteiro, Gabriela Coelho Itaya, Nathan Kong, Andre d'Avila","doi":"10.36660/abc.20240301","DOIUrl":"https://doi.org/10.36660/abc.20240301","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240301"},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is This a Causal Relationship? Mendelian Randomization as a Statistical Method for Unraveling Connections. 这是因果关系吗?孟德尔随机化作为一种揭示联系的统计方法。
Arquivos brasileiros de cardiologia Pub Date : 2024-11-15 eCollection Date: 2024-01-01 DOI: 10.36660/abc.20240606
Lucas Vieira Lacerda Pires
{"title":"Is This a Causal Relationship? Mendelian Randomization as a Statistical Method for Unraveling Connections.","authors":"Lucas Vieira Lacerda Pires","doi":"10.36660/abc.20240606","DOIUrl":"https://doi.org/10.36660/abc.20240606","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240606"},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Pulsed Field Ablation on Atrial Fibrillation. 脉冲场消融术对心房颤动的影响
Arquivos brasileiros de cardiologia Pub Date : 2024-11-15 eCollection Date: 2024-01-01 DOI: 10.36660/abc.20240565
Mauricio Scanavacca, Cristiano Pisani
{"title":"Impact of Pulsed Field Ablation on Atrial Fibrillation.","authors":"Mauricio Scanavacca, Cristiano Pisani","doi":"10.36660/abc.20240565","DOIUrl":"https://doi.org/10.36660/abc.20240565","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240565"},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potentially Inappropriate Cardioverter Defibrillator Implants in Secondary Prevention of Death. 在死亡二级预防中植入潜在不当的心律转复除颤器。
Arquivos brasileiros de cardiologia Pub Date : 2024-11-11 eCollection Date: 2024-01-01 DOI: 10.36660/abc.20220899
William Neves de Carvalho, Tainá Teixeira Viana, Clara Salles Figueiredo, Fernanda Martins, Luiz Carlos Santana Passos
{"title":"Potentially Inappropriate Cardioverter Defibrillator Implants in Secondary Prevention of Death.","authors":"William Neves de Carvalho, Tainá Teixeira Viana, Clara Salles Figueiredo, Fernanda Martins, Luiz Carlos Santana Passos","doi":"10.36660/abc.20220899","DOIUrl":"https://doi.org/10.36660/abc.20220899","url":null,"abstract":"<p><strong>Background: </strong>Implantable cardioverter defibrillators (ICDs) are recommended for patients experiencing malignant tachyarrhythmias due to irreversible causes, who are clinically stable, and have a life expectancy exceeding one year. However, adverse socioeconomic and psychosocial conditions can adversely affect short-term survival and may render implantation inappropriate.</p><p><strong>Objective: </strong>To assess whether economic and psychosocial markers (EPSM) are associated with higher mortality in the first year (indicating potentially inappropriate implants) following ICD implantation.</p><p><strong>Methods: </strong>A prospective cohort study conducted between 2017 and 2021 included patients with heart failure and left ventricular ejection fraction (LVEF) < 50% who underwent ICD implantation for secondary prophylaxis. Prior to the procedure, patients were evaluated by an MDT, which examined four EPSM variables, namely socioeconomic vulnerability, self-care capacity, pharmacological adherence, and mood disorders. The participants were monitored for at least 12 months. Statistical significance was considered to be p-values < 0.05.</p><p><strong>Results: </strong>A total of 208 individuals were included, with 144 (68.9%) being male. The mean LVEF was 32% ±9 and 107 (51%) had Chagas disease etiology. The mortality rate in the first year was 54/208 (25.8%). All patients who died had at least one of the EPSM and there no deaths were reported among the 73 (35.4%) who did not have EPSM. In multivariate analysis, having EPSM and LVEF were the only independent predictors of mortality under 1 year: RR 20.48 (2.75 - 52.29); p=0.003 and RR 0.97 (0.93 - 0.99); p=0.047, respectively.</p><p><strong>Conclusion: </strong>Socioeconomic and psychosocial conditions should be identified and, where possible, resolved before implantation, as they may make device implantation a potentially inappropriate procedure.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20220899"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial Cardiomyopathy and Hypertension: Connections between Arterial Stiffness and Subclinical Atrial Arrhythmias. 房性心肌病与高血压:动脉僵化与亚临床房性心律失常之间的联系。
Arquivos brasileiros de cardiologia Pub Date : 2024-11-11 eCollection Date: 2024-01-01 DOI: 10.36660/abc.20240598
Ronaldo Altenburg Gismondi, Mario Fritsch Neves
{"title":"Atrial Cardiomyopathy and Hypertension: Connections between Arterial Stiffness and Subclinical Atrial Arrhythmias.","authors":"Ronaldo Altenburg Gismondi, Mario Fritsch Neves","doi":"10.36660/abc.20240598","DOIUrl":"https://doi.org/10.36660/abc.20240598","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240598"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors, Management, and Evolution after the First Acute Myocardial Infarction: A Real-World Study Comparing Cohorts of Women and Men in the TriNetX Network. 首次急性心肌梗死后的风险因素、管理和演变:比较 TriNetX 网络中男女群组的真实世界研究。
Arquivos brasileiros de cardiologia Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.36660/abc.20230692
Camila Mota Guida, Eduardo Juvenal de Souza, Leandro Menezes Alves da Costa, Thiago Luis Scudeler, Rafael Amorim Belo Nunes, Gustavo Bernardes de Figueiredo Oliveira
{"title":"Risk Factors, Management, and Evolution after the First Acute Myocardial Infarction: A Real-World Study Comparing Cohorts of Women and Men in the TriNetX Network.","authors":"Camila Mota Guida, Eduardo Juvenal de Souza, Leandro Menezes Alves da Costa, Thiago Luis Scudeler, Rafael Amorim Belo Nunes, Gustavo Bernardes de Figueiredo Oliveira","doi":"10.36660/abc.20230692","DOIUrl":"10.36660/abc.20230692","url":null,"abstract":"<p><strong>Background: </strong>International cohort studies have consistently demonstrated an unfavorable prognosis in female patients after the first acute myocardial infarction (AMI) over the past decades. However, national data on this topic are limited.</p><p><strong>Objectives: </strong>This study aims to compare national cohorts of men and women hospitalized due to the first acute myocardial infarction, examining long-term outcomes.</p><p><strong>Methods: </strong>A retrospective, observational study using real-world data extracted from the global TriNetX platform, including patients of both sexes with a confirmed diagnosis of AMI according to the International Classification of Diseases (ICD), version 11, code I21. The level of statistical significance adopted in the analysis was 5% (0.05). The primary outcome assessed was a composite of death, new hospitalization for AMI, myocardial revascularization procedures, or heart failure after the hospital phase with a 5-year follow-up.</p><p><strong>Results: </strong>Data from 29,041 patients were evaluated, of which 11,284 (38.4%) were women. The mean age of the female and male populations was 64.4 and 59.8 years, respectively. The group of women showed a higher occurrence of the composite outcome of death, new hospitalization for AMI, myocardial revascularization procedures, or heart failure after the hospital phase with a 5-year follow-up (OR 1.058; CI 1.005 - 1.113; p = 0.03).</p><p><strong>Conclusions: </strong>In this large Brazilian cohort, the female sex was associated with a higher occurrence of cardiovascular events within 5 years after hospital discharge.</p><p><strong>Background: </strong>Real-world study comparing female and male cohorts in the TriNetX network.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20230692"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiovascular Computed Tomography and Magnetic Resonance Imaging Guideline of the Brazilian Society of Cardiology and the Brazilian College of Radiology - 2024. 巴西心脏病学会和巴西放射学院心血管计算机断层扫描和磁共振成像指南 - 2024》。
Arquivos brasileiros de cardiologia Pub Date : 2024-10-28 DOI: 10.36660/abc.20240608
Tiago Augusto Magalhães, Adriano Camargo de Castro Carneiro, Valéria de Melo Moreira, Henrique Simão Trad, Marly Maria Uellendahl Lopes, Rodrigo Julio Cerci, Marcelo Souto Nacif, Paulo R Schvartzman, Antônio Carlos Palandrini Chagas, Isabela Bispo Santos da Silva Costa, André Schmidt, Afonso Akio Shiozaki, Sérgio Tavares Montenegro, Leopoldo Soares Piegas, Marcelo Zapparoli, José Carlos Nicolau, Fabio Fernandes, Marcelo Souza Hadlich, Nabil Ghorayeb, Evandro Tinoco Mesquita, Luiz Flávio Galvão Gonçalves, Felix José Alvarez Ramires, Juliano de Lara Fernandes, Pedro Vellosa Schwartzmann, Salvador Rassi, Jorge Andion Torreão, José Carlos Pachón Mateos, Luiz Beck-da-Silva, Marly Conceição Silva, Gabriela Liberato, Gláucia Maria Moraes de Oliveira, Gilson Soares Feitosa Filho, Hilka Dos Santos Moraes de Carvalho, Brivaldo Markman Filho, Ricardo Paulo de Sousa Rocha, Clerio Francisco de Azevedo Filho, Flávio Taratsoutchi, Otavio Rizzi Coelho-Filho, Roberto Kalil Filho, Ludhmila Abrahão Hajjar, Walther Yoshiharu Ishikawa, Cíntia Acosta Melo, Ieda Biscegli Jatene, Andrei Skromov de Albuquerque, Carolina de Medeiros Rimkus, Paulo Savoia Dias da Silva, Thiago Dieb Ristum Vieira, Fabio Biscegli Jatene, Guilherme Sant Anna Antunes de Azevedo, Raul D Santos, Guilherme Urpia Monte, José Antonio Franchini Ramires, Marcio Sommer Bittencourt, Alvaro Avezum, Leonardo Sara da Silva, Alexandre Abizaid, Ilan Gottlieb, Dalton Bertolim Precoma, Gilberto Szarf, Antônio Carlos Sobral Sousa, Ibraim Masciarelli Francisco Pinto, Fábio de Morais Medeiros, Bruno Caramelli, José Rodrigues Parga Filho, Tiago Senra Garcia Dos Santos, Carlos Eduardo Elias Dos Prazeres, Marcelo Antonio Cartaxo Queiroga Lopes, Luiz Francisco Rodrigues de Avila, Mauricio Ibrahim Scanavacca, Luis Henrique Wolff Gowdak, Silvio Henrique Barberato, Cesar Higa Nomura, Carlos Eduardo Rochitte
{"title":"Cardiovascular Computed Tomography and Magnetic Resonance Imaging Guideline of the Brazilian Society of Cardiology and the Brazilian College of Radiology - 2024.","authors":"Tiago Augusto Magalhães, Adriano Camargo de Castro Carneiro, Valéria de Melo Moreira, Henrique Simão Trad, Marly Maria Uellendahl Lopes, Rodrigo Julio Cerci, Marcelo Souto Nacif, Paulo R Schvartzman, Antônio Carlos Palandrini Chagas, Isabela Bispo Santos da Silva Costa, André Schmidt, Afonso Akio Shiozaki, Sérgio Tavares Montenegro, Leopoldo Soares Piegas, Marcelo Zapparoli, José Carlos Nicolau, Fabio Fernandes, Marcelo Souza Hadlich, Nabil Ghorayeb, Evandro Tinoco Mesquita, Luiz Flávio Galvão Gonçalves, Felix José Alvarez Ramires, Juliano de Lara Fernandes, Pedro Vellosa Schwartzmann, Salvador Rassi, Jorge Andion Torreão, José Carlos Pachón Mateos, Luiz Beck-da-Silva, Marly Conceição Silva, Gabriela Liberato, Gláucia Maria Moraes de Oliveira, Gilson Soares Feitosa Filho, Hilka Dos Santos Moraes de Carvalho, Brivaldo Markman Filho, Ricardo Paulo de Sousa Rocha, Clerio Francisco de Azevedo Filho, Flávio Taratsoutchi, Otavio Rizzi Coelho-Filho, Roberto Kalil Filho, Ludhmila Abrahão Hajjar, Walther Yoshiharu Ishikawa, Cíntia Acosta Melo, Ieda Biscegli Jatene, Andrei Skromov de Albuquerque, Carolina de Medeiros Rimkus, Paulo Savoia Dias da Silva, Thiago Dieb Ristum Vieira, Fabio Biscegli Jatene, Guilherme Sant Anna Antunes de Azevedo, Raul D Santos, Guilherme Urpia Monte, José Antonio Franchini Ramires, Marcio Sommer Bittencourt, Alvaro Avezum, Leonardo Sara da Silva, Alexandre Abizaid, Ilan Gottlieb, Dalton Bertolim Precoma, Gilberto Szarf, Antônio Carlos Sobral Sousa, Ibraim Masciarelli Francisco Pinto, Fábio de Morais Medeiros, Bruno Caramelli, José Rodrigues Parga Filho, Tiago Senra Garcia Dos Santos, Carlos Eduardo Elias Dos Prazeres, Marcelo Antonio Cartaxo Queiroga Lopes, Luiz Francisco Rodrigues de Avila, Mauricio Ibrahim Scanavacca, Luis Henrique Wolff Gowdak, Silvio Henrique Barberato, Cesar Higa Nomura, Carlos Eduardo Rochitte","doi":"10.36660/abc.20240608","DOIUrl":"https://doi.org/10.36660/abc.20240608","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240608"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum. 勘误。
Arquivos brasileiros de cardiologia Pub Date : 2024-10-28 DOI: 10.36660/abc.20240582
{"title":"Erratum.","authors":"","doi":"10.36660/abc.20240582","DOIUrl":"https://doi.org/10.36660/abc.20240582","url":null,"abstract":"<p><p>[This corrects the article doi: 10.36660/abc.20200690] [This corrects the article doi: 10.36660/abc.20200690].</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240582"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endomyocardial Biopsy Using Rigid Bioptome Technique and the Risk of Tricuspid Regurgitation after Heart Transplantation. 使用刚性生物光束技术进行心内膜活检与心脏移植后三尖瓣反流的风险
Arquivos brasileiros de cardiologia Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.36660/abc.20240223
Luís Beck-da-Silva, Leonardo Hennig Bridi, Bruno S Matte, Felipe Homem Valle
{"title":"Endomyocardial Biopsy Using Rigid Bioptome Technique and the Risk of Tricuspid Regurgitation after Heart Transplantation.","authors":"Luís Beck-da-Silva, Leonardo Hennig Bridi, Bruno S Matte, Felipe Homem Valle","doi":"10.36660/abc.20240223","DOIUrl":"https://doi.org/10.36660/abc.20240223","url":null,"abstract":"<p><p>Endomyocardial biopsy (EB) is the preferred procedure for post-heart transplant rejection diagnosis. The rigid bioptome technique has been used due to its greater simplicity and has been criticized for the potential risk of tricuspid regurgitation (TR). We aimed to review all the EBs performed by this technique in a tertiary center and estimate the rate of complications and/or aggravation of TR. Cross-sectional, retrospective, anterograde study. Data were collected from 729 EBs performed in 55 post-heart transplant patients with a rigid Scholten Novatome™ bioptome between September 2012 to March 2022. All EBs were performed via the right jugular vein under local anesthesia and through micro-puncture and ultrasound guidance. A total of 729 procedures had an echocardiography performed before and after the procedures. The estimate of TR was categorized as absent, minimal, mild, moderate, and severe. McNemar's chi-square test was used to analyze the degree of pre- and post-EB TR. There was a worsening enough to become moderate or severe post-biopsy TR in two (0.27%) procedures, and there was a slight change in TR from minimal to mild TR in 25 (3.42%) procedures. In 729 percutaneous EBs performed with a rigid bioptome, there was no myocardial perforation, cardiac tamponade or pneumothorax. One death occurred within 24 hours after the procedure for an unknown reason. EB using a rigid bioptome is safe and has not been associated with worsening TR in a follow-up of 729 EBs performed after cardiac transplantation. The overall complication rate, including moderate to severe TR, was 0.81%. The mortality rate was 0.14%.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20240223"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal Relationship between Television Viewing Time, Cardiovascular Diseases, and Potential Mechanisms. 电视观看时间与心血管疾病之间的因果关系及潜在机制。
Arquivos brasileiros de cardiologia Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.36660/abc.20230796
Mengjin Hu, Boyu Li, Jinggang Xia, Chunlin Yin, Yuejin Yang
{"title":"Causal Relationship between Television Viewing Time, Cardiovascular Diseases, and Potential Mechanisms.","authors":"Mengjin Hu, Boyu Li, Jinggang Xia, Chunlin Yin, Yuejin Yang","doi":"10.36660/abc.20230796","DOIUrl":"10.36660/abc.20230796","url":null,"abstract":"<p><strong>Background: </strong>As the predominant leisure-time sedentary behavior, television viewing was documented to increase cardiovascular diseases in observational studies, yet the causal relationship and potential mechanisms remain to be determined.</p><p><strong>Objectives: </strong>To systematically investigate the causal relationship between television viewing time, cardiovascular diseases, and potential mechanisms.</p><p><strong>Methods: </strong>We conducted a two-sample Mendelian randomization (MR) analysis to estimate causal associations with cardiovascular diseases and biomarkers of cardiometabolic risk. The random inverse-variance weighted method was used as the primary estimate. To account for multiple comparisons, a Bonferroni correction p value for cardiovascular diseases and biomarkers of cardiometabolic risk was 0.0045 and 0.0024, respectively.</p><p><strong>Results: </strong>Genetically instrumented television viewing time was associated with higher risks of type 2 diabetes (odd ratio [OR]=2.51; 95% confidence interval [CI]: 1.89-3.33; p<0.00001), hypertension (OR=2.11; 95% CI: 1.67-2.66; p<0.00001), coronary heart disease (OR=1.53; 95% CI: 1.23-1.91; p=0.00015), and heart failure (OR=1.42; 95% CI: 1.18-1.70; p=0.00017). Suggestive evidence of harmful associations was also observed for peripheral artery disease (OR=1.58; 95% CI: 1.07-2.34; p=0.02253) and ischemic stroke (OR=1.34; 95% CI: 1.10-1.63; p=0.00328). Biomarkers of cardiometabolic risk, including interleukin 10, leptin, visceral adipose, abdominal subcutaneous adipose, liver fat, body mass index, waist circumference, triglycerides, and C-reactive protein, were increased. Systolic blood pressure, heart rate, low-density lipoprotein, and total cholesterol were potentially increased while high-density lipoprotein was decreased. However, television viewing time had no effect on venous thromboembolism or pulmonary embolism.</p><p><strong>Conclusion: </strong>Television viewing time was causally associated with increased risks of cardiovascular diseases, which may be explained by metabolic and inflammatory mechanisms.</p><p><strong>Background: </strong>An overview of the effect of television viewing time on cardiovascular diseases and biomarkers of cardiometabolic risk.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 10","pages":"e20230796"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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