Arquivos brasileiros de cardiologia最新文献

{"title":"Fixed-Dose Antiplatelet Dual Combination in Patients with Coronary Artery Disease in Turkish Population: DAPT-TR.","authors":"Ahmet Öz, Kenan Toprak, Ertan Aydin, İbrahim Saraç, Mustafa Doğduş, Selçuk Opan, Mustafa Yenerçağ, Mustafa Begenc Tascanov, Ömer Kümet, Miraç Karaağaç, Murat Özmen, Bektaş Murat, Ömer Kertmen, Özkan Bekler, Sinan İnci, Mustafa Ahmet Huyut, Ahmet Özderya, Fahri Er, Mustafa Duran, İsa Ardahanlı, Mehmet Memduh Baş, Tuncay Güzel, Gökhan Ceyhun, İbrahim Halil Özdemir, Mehmet Burak Özen, Ramazan Gündüz, Aslan Erdoğan, İlyas Çetin, Veysel Özgür Barış, Çağrı Yayla, Medeni Karaduman, Lütfü Aşkın, Lütfü Bekar, Okan Tanrıverdi, Eyüp Özkan, Emrah Yeşil, Serhat Çalışkan, Zülfiye Kuzu, Berat Uğuz, Ferit Böyük, Ayşegül Ülgen Kunak, Selda Murat, Serkan Asil, Özkan Kayhan, Emrah Erdoğan, Ramazan Duz, Fahrettin Katkat, Tuba Ekin, Ersin İbişoğlu, Bilge Nazar Ateş, Burak Ayça, Asım Oktay Ergene, Mehdi Zoghi","doi":"10.36660/abc.20240202","DOIUrl":"10.36660/abc.20240202","url":null,"abstract":"<p><strong>Background: </strong>Dual antiplatelet therapy (DAPT) is the treatment of choice for patients with acute and chronic coronary syndromes as it reduces mortality and prevents recurrent thrombotic complications. The assessment of both ischaemic burden and bleeding risk is crucial in deciding which DAPT to choose and how long it should be continued.</p><p><strong>Objectives: </strong>The aim of our study was to perform prospective clinical follow-up of patients receiving fixed-dose combination therapy (ASA 75 mg + clopidogrel 75 mg). Our study is a multicentric, cross-sectional, observational, cohort study.</p><p><strong>Methods: </strong>A total of 1500 patients who were started on fixed-dose combination DAPT for acute or chronic coronary syndrome were included in the study. Primary endpoints were hospitalization for any reason, hospitalization for cardiovascular cause, acute myocardial infarction, stent thrombosis, target vessel revascularization and bleeding; the secondary endpoints were death for any reason or cardiovascular cause and stroke. The significance level adopted in the statistical analysis was 5%.</p><p><strong>Results: </strong>Median age was 63 years; 78.5% of the patients were receiving DAPT treatment for acute coronary syndrome. The rates of hospitalization for cardiovascular reasons, acute myocardial infartion, stent thrombosis and target-vessel revascularization were 7.9%, 2.3%, 1.3% and 4.2%, respectively. While the rate of BARC type 1 bleeding was 3.3%, the rate of BARC type 5, 3, or 2 bleeding was 0.6%. The secondary endpoints which were death from any cause, cardiovascular death and stroke were 0.5%, 0.3% and 0.3%, respectively. Conclusion: Our study shows that fixed-dose combination therapy is effective and safe in appropriately selected patients with acute or chronic coronary syndromes.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 11","pages":"e20240202"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Myocardial Flow Reserve Using the CZT Camera. Additional Value to Perfusion and Functional Information in Identifying the Cause of Chest Discomfort.","authors":"Paola Emanuela Poggio Smanio","doi":"10.36660/abc.20240366","DOIUrl":"10.36660/abc.20240366","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 6","pages":"e20240366"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"No Time to Die.","authors":"Luiz Fernando Caneo","doi":"10.36660/abc.20240512","DOIUrl":"10.36660/abc.20240512","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240512"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRKAG2 Syndrome: Is Screening with Early Echocardiography Effective in Children with a Positive Genotype?","authors":"Maria Elisa Lucena Sales de Melo Assunção, Norma Lucena Cavalcanti Licínio da Silva, Mychelle Pascoaline de Miranda Silva","doi":"10.36660/abc.20240543","DOIUrl":"10.36660/abc.20240543","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240543"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Chagasic Cardiomyopathy: Influence of Physical Exercise.","authors":"Gustavo Augusto Ferreira Mota, Mariana Gatto, Vitor Loureiro da Silva, Paula Felippe Martinez, Marina Politi Okoshi","doi":"10.36660/abc.20240507","DOIUrl":"10.36660/abc.20240507","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240507"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Look Who is Coming Back? Enhancing Predictive Models for Hospital Readmission Post-CABG: Insights and Perspectives.","authors":"Stephan Lachtermacher","doi":"10.36660/abc.20240493","DOIUrl":"10.36660/abc.20240493","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240493"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11516155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Program to Optimize the Detection of Paroxysmal Atrial Fibrillation: The RITMO Study.","authors":"Rodrigo Paashaus de Andrade, Priscila Valverde Oliveira Vitorino, Ana Luiza Lima Sousa, Roberto Dischinger Miranda, Bruno Augusto Alcova Nogueira, Elizabeth do Espírito Santo Cestário, Marcus Vinícius de Oliveira, Luiz Kencis Júnior, Fernando Cenci Tormen, Pablo de Oliveira Antunes, Ivan Di Beo, Luiz Eduardo Guiselli Gallina, Weimar Kunz Sebba Barroso","doi":"10.36660/abc.20240235","DOIUrl":"10.36660/abc.20240235","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF) is the most common sustained arrythmia, but still underdiagnosed especially among asymptomatic patients.</p><p><strong>Objectives: </strong>To evaluate a simple strategy to optimize the identification of AF.</p><p><strong>Methods: </strong>Asymptomatic patients aged 65 years or older, with hypertension or heart failure (HF), were included. Data were inserted into the REDCap software platform. Patients were assessed for the risk for AF using the Stroke Risk Analysis (SRA) mathematical algorithm, which was applied on a one-hour electrocardiogram (ECG). All patients at high risk for AF were instructed to follow a home ECG protocol for seven days using a portable Kardia 6 (OMRON, AliveCor®). The Kolmogorov-test was used to test the normality of quantitative variables; those with normal distribution were expressed as mean and standard deviation. A p<0.05 was set as statistically significant.</p><p><strong>Results: </strong>A total of 423 patients were assessed; 15 were excluded due to absence of SRA, yielding a sample of 408 patients. In 13 (3.2%), AF was identified, 120 (29.4%) were considered at high risk and 275 (67.4%) without increased risk for AF. Of the 120 high-risk patients, 111 successfully completed the seven-day protocol with Kardia; at least one episode of AF was identified in 43 patients.</p><p><strong>Conclusion: </strong>The strategy adopted in the RITMO study was shown to be effective in identifying AF in asymptomatic elderly patients with hypertension or HF, with an incidence of 13.7% (56/408).</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240235"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Anticoagulant Therapy in Obese People: What is the Evidence for the Ideal Dose?","authors":"Marcia M Noya-Rabelo, Eduardo Novaes, Renata Moll-Bernardes, Olga Souza","doi":"10.36660/abc.20240496","DOIUrl":"10.36660/abc.20240496","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240496"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resting Heart Rate to Assess Patients with Heart Failure: That is All We Need.","authors":"Humberto Villacorta","doi":"10.36660/abc.20240521","DOIUrl":"10.36660/abc.20240521","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 8","pages":"e20240521"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Severe Heart Disease on Causes of Death and Survival after Disability Retirement.","authors":"Cesar Romaro Pozzobon, Gabriel Porto Soares, Ronir Raggio Luiz, Gláucia Maria Moraes de Oliveira","doi":"10.36660/abc.20240068","DOIUrl":"10.36660/abc.20240068","url":null,"abstract":"<p><strong>Background: </strong>Noncommunicable diseases contribute to premature deaths and limitations. Disability retirement is linked to chronic conditions, particularly cardiovascular diseases. The II Brazilian Guideline for Severe Heart Disease established criteria for cardiovascular disease classification. However, there is a lack of research in this topic within federal institutions.</p><p><strong>Objectives: </strong>Evaluate the survival and causes of death among disabled retirees at UFRJ, focusing on the impact of severe heart disease.</p><p><strong>Methods: </strong>A retrospective cohort study based on retirement and death records over 15 years. Retirements were categorized into three groups: full retirement due to severe heart disease, full retirement due to other diseases and proportional. Causes of death were obtained from death certificates. Mortality rates, survival and the presence of matching diagnoses between retirement and death were evaluated. Chi-square, log-rank, Cox models, Kaplan-Meier curves were utilized. Statistical significance with a 95% confidence interval, considering p<0.05.</p><p><strong>Results: </strong>There were 630 retirements, 368 (51.4%) in females, with an average age of 52.9 (SD=7.8) years, and 169 (26.8%) deaths. Mortality was higher in professors (37.0%; p=0.113), in the age group between 65 and 70 years (48.4%; p=0.004), in males (34.0%; p=0.001), and in full retirements due to severe heart disease (41.5%; p<0.001). Matching diagnoses between retirement and death were more frequent in professors (74.1%; p=0.026) and in full retirements due to severe heart disease (72.7%; p<0.001).</p><p><strong>Conclusions: </strong>Severe heart disease diagnosis is associated with higher mortality and shorter survival in disabled retirees. Its frequent occurrence in retirement and death diagnoses underscores its significance in this context.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"121 9","pages":"e20240068"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}