Rodrigo Guimarães Vieira de Carvalho, Gustavo Augusto Ferreira Mota, Milene Vitória Sampaio Sobral, Ana Paula Coelho Figueira Freire, Francis Lopes Pacagnelli
{"title":"Cardiac Response to Stress: Influence of Vortioxetine.","authors":"Rodrigo Guimarães Vieira de Carvalho, Gustavo Augusto Ferreira Mota, Milene Vitória Sampaio Sobral, Ana Paula Coelho Figueira Freire, Francis Lopes Pacagnelli","doi":"10.36660/abc.20250105","DOIUrl":"https://doi.org/10.36660/abc.20250105","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 2","pages":"e20250105"},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Datasus: An Essential Tool for Public Health in Brazil.","authors":"Marcia Koike","doi":"10.36660/abc.20250123","DOIUrl":"https://doi.org/10.36660/abc.20250123","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 2","pages":"e20250123"},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Carlos Pachon-M, Enrique I Pachon-M, Tasso J Lobo, Tomas G Santillana-P, Carlos Thiene C Pachon
{"title":"High-Power Short Duration or Pulsed Field Ablation: What is the Best Choice for AF Ablation?","authors":"José Carlos Pachon-M, Enrique I Pachon-M, Tasso J Lobo, Tomas G Santillana-P, Carlos Thiene C Pachon","doi":"10.36660/abc.20250057","DOIUrl":"https://doi.org/10.36660/abc.20250057","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 2","pages":"e20250057"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Gabriel Melo de Barros E Silva, Valter Furlan, Renato D Lopes, André Volschan, Paulo Cesar Pereira de Souza, Carisi Anne Polanczyk
{"title":"Value-Based Healthcare in Cardiology: How to Integrate a more Comprehensive View into Medical Decision-Making?","authors":"Pedro Gabriel Melo de Barros E Silva, Valter Furlan, Renato D Lopes, André Volschan, Paulo Cesar Pereira de Souza, Carisi Anne Polanczyk","doi":"10.36660/abc.20240668","DOIUrl":"10.36660/abc.20240668","url":null,"abstract":"<p><p>Value-based healthcare is a patient-centered concept that provides a broad view of all parties involved in the care process. This model is designed to achieve the best possible patient outcomes while maintaining cost sustainability. In its classic description, value-based care is the relationship between outcomes that matter to the patient and the costs required to achieve them. Later, other variables were considered in this equation, such as appropriateness and user experience, to make this model more replicable. With a view that aligns the interests of patients, physicians, and payers, value-based healthcare has great potential to improve medical practice sustainably. After more than a decade of discussions and publications, putting this concept into practice is still challenging and dynamic. Value-based healthcare has gained importance and should become a transformative model for health ecosystems. Medical compensation aligned with these principles appears to be a promising path toward such transformation. Nevertheless, the application of this concept depends on a more straightforward definition of the health value parameters in different clinical scenarios. Cardiology is a specialty that usually has a solid evidence base for medical decision-making and this generates great potential for the application of health value elements. In this article, the authors outline a review of the main concepts of value-based healthcare and its potential applications in cardiology.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 2","pages":"e20240668"},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberto Cintra de Azevedo Aragão, José Augusto Soares Barreto-Filho, Roney Orismar Sampaio
{"title":"The Culprit Valve: A New Concept for Reducing the Risk of Intervention in Patients with Severe Valve Disease.","authors":"Roberto Cintra de Azevedo Aragão, José Augusto Soares Barreto-Filho, Roney Orismar Sampaio","doi":"10.36660/abc.20240492","DOIUrl":"https://doi.org/10.36660/abc.20240492","url":null,"abstract":"","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 4","pages":"e20240492"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hugo Baldisserotto, Barbara Adelmann de Lima, Marco Aurélio Lumertz Saffi, Anderson Donelli da Silveira, Marcia Leonardi Baldisserotto, Tiago Luiz Luz Leiria
{"title":"Mortality and Ventricular Arrhythmia in Patients with Early Ventricular Repolarization.","authors":"Hugo Baldisserotto, Barbara Adelmann de Lima, Marco Aurélio Lumertz Saffi, Anderson Donelli da Silveira, Marcia Leonardi Baldisserotto, Tiago Luiz Luz Leiria","doi":"10.36660/abc.20240516","DOIUrl":"https://doi.org/10.36660/abc.20240516","url":null,"abstract":"<p><strong>Background: </strong>Recent research has linked early repolarization (ER) with increased ventricular fibrillation risk, especially in leads V1-V3 and in inferior and lateral regions. However, data on the Brazilian population are limited.</p><p><strong>Objective: </strong>To estimate the impact of ER on survival and the occurrence of ventricular arrhythmias (VA) in patients over a 10-year period at a university hospital.</p><p><strong>Methods: </strong>This retrospective cohort study included patients with ER on electrocardiogram from the hospital database. Descriptive analysis was conducted to describe patients' profile and characteristics. Kaplan-Meier method was utilized to analyze survival curves, with the log-rank test employed to assess differences between ER types. Cox regression models were applied to evaluate the risks of death and VA, calculating both gross and adjusted hazard ratios. The level of significance adopted in the statistical analysis was 5%.</p><p><strong>Results: </strong>The study population was predominantly male, average age of 45.6 years; 2.7% experienced VA (five in the group with lateral ER, four in the group with inferior ER group, and four in the ER inferolateral group). Significant differences were observed in age, sex, and HFrEF between the groups. Regarding all-cause mortality, 2.3% of patients died (five in the group with lateral ER, one in the group with inferior ER group, and five in the ER inferolateral group). Only age showed a statistically significant difference. There were significant differences in both death and VA between the groups (p=0.7 and p=0.5, respectively).</p><p><strong>Conclusion: </strong>ER did not lead to a higher incidence of VA or all-cause mortality in this cohort.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 4","pages":"e20240516"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Bassan, Roberto Esporcatte, Marcelo Goulart Correia, Octavio Drummond Guina, Guilherme de Souza Weigert, Gracielle Christine do Nascimento Oliveira
{"title":"The Effect of Coronary Artery Bypass Graft Surgery on Contractile Function and Symptoms in Patients with Left Ventricular Dysfunction.","authors":"Fernando Bassan, Roberto Esporcatte, Marcelo Goulart Correia, Octavio Drummond Guina, Guilherme de Souza Weigert, Gracielle Christine do Nascimento Oliveira","doi":"10.36660/abc.20240486","DOIUrl":"https://doi.org/10.36660/abc.20240486","url":null,"abstract":"<p><strong>Background: </strong>The degree of left ventricular (LV) dysfunction is an independent risk factor for poor outcomes in patients with chronic coronary syndrome. Coronary artery bypass graft (CABG) is the standard care for the management of ischemic heart failure to improve symptoms and prognosis. However, the predictors of improvement are still uncertain.</p><p><strong>Objective: </strong>To assess the effect of myocardial revascularization on LV function and symptoms in patients with CCS and reduced left ventricular ejection fraction (LVEF), as well as to identify the improvement predictors.</p><p><strong>Methods: </strong>We retrospectively analyzed the data and clinical status of 136 consecutive patients with LVEF<50% that underwent CABG. During clinical follow-up echocardiographic LV function was reassessed at the short-term (3.6 months) and long-term (30.8 months), and compared to baseline.</p><p><strong>Results: </strong>Mean pre-operative LVEF was 40.9 ± 8.6% and wall motion score index (WMSI) was 1.99 ± 0.36, both improving at long-term to 48.1 ± 15.0% (p<0.001) and 1.75 ± 0.49 (p<0.001), respectively. We observed that 55.7% of the patients presented an improvement of LVEF≥10% and 58.1% in WMSI ≥10%. Univariate logistic regression analysis revealed that cerebrovascular disease was the only variable to be predictor of LVEF improvement. At the end of follow-up, we observed a reduction in the rate of patients in functional class III/IV when compared to baseline (65.4 vs. 10.3% - p<0.001).</p><p><strong>Conclusions: </strong>Patients with CCS and reduced LVEF undergoing CABG experienced improvement in both LV contractile function and size, with beneficial response in functional class.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 4","pages":"e20240486"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernanda Burger Zimmermann, Sérgio Luiz Zimmermann, Marcelo Burger Zimmermann, Enrico Klug Beraldi, Mateus Campanelli Franco da Rocha, Bruno Pereira de Oliveira Zabot, Siegmar Starke, Ernani Tiaraju de Santa Helena, Marcello Ricardo Paulista Markus
{"title":"Association between Cardiovascular Risk Factors and Carotid Plaques in a Population-Based Study - The SHIP-Brazil Study.","authors":"Fernanda Burger Zimmermann, Sérgio Luiz Zimmermann, Marcelo Burger Zimmermann, Enrico Klug Beraldi, Mateus Campanelli Franco da Rocha, Bruno Pereira de Oliveira Zabot, Siegmar Starke, Ernani Tiaraju de Santa Helena, Marcello Ricardo Paulista Markus","doi":"10.36660/abc.20240546","DOIUrl":"https://doi.org/10.36660/abc.20240546","url":null,"abstract":"<p><strong>Background: </strong>Atherosclerotic disease is a relevant cause of morbidity and mortality in the general population, and it is important to detect factors that can influence its prevention.</p><p><strong>Objective: </strong>To evaluate the association of cardiovascular risk factors with carotid plaques in participants of the Study of Health in Pomerania (SHIP) - Brazil.</p><p><strong>Methods: </strong>A total of 1,953 participants were assessed for the presence of cardiovascular risk factors (hypertension, dyslipidemia, type 2 diabetes, obesity, smoking and physical inactivity) and sociodemographic variables (gender, age group, Germanic culture, color/race self-declared, and alcohol consumption), waist circumference measurement, waist-to-hip ratio and waist-to-height ratio. The presence of carotid plaques was analyzed by ultrasound. The association between the study variables and carotid plaques was assessed using the Chi-square test. A p-value < 0.05 was considered significant.</p><p><strong>Results: </strong>Plaques were present in 56.5% of hypertensive patients (p<0.001), 49.8% of dyslipidemic patients (p<0.001), 62% of diabetic patients (p<0.001), 52% of smokers, 29% of those who had never smoked (p<0.001), 39.5% of sedentary people and 33.1% of non-sedentary people (p=0.014), 43.7% of obese people and 26.1% of eutrophic people (p<0.001).</p><p><strong>Conclusion: </strong>Carotid plaques were prevalent in men, aged between 60 and 79, white, hypertensive, dyslipidemic, diabetic, smokers, sedentary and obese, illiterate, in economic class A1/A2, and of Germanic culture, and low alcohol consumption.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 3","pages":"e20240546"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgina Del Cisne Jadán Luzuriaga, Edmundo Arteaga-Fernandez, Viviane Tiemi Hotta, Barbara Ianni, Luciano Nastari, Felix Ramires, Guilherme Wesley Peixoto da Fonseca, Charles Mady, Fábio Fernandes, Juliano Novaes Cardoso
{"title":"Clinical and Echocardiographic Particularities of Hypertrophic Cardiomyopathy in a Brazilian Population and its Prognostic Impact.","authors":"Georgina Del Cisne Jadán Luzuriaga, Edmundo Arteaga-Fernandez, Viviane Tiemi Hotta, Barbara Ianni, Luciano Nastari, Felix Ramires, Guilherme Wesley Peixoto da Fonseca, Charles Mady, Fábio Fernandes, Juliano Novaes Cardoso","doi":"10.36660/abc.20240640","DOIUrl":"https://doi.org/10.36660/abc.20240640","url":null,"abstract":"<p><strong>Background: </strong>Hypertrophic cardiomyopathy (HCM) presents echocardiographic abnormalities that are important for diagnosis and prognosis. Data are scarce in the Brazilian literature.</p><p><strong>Objective: </strong>To assess clinical and echocardiographic characteristics and disease progression in a Brazilian cohort of patients with HCM.</p><p><strong>Methods: </strong>This retrospective cohort included patients with HCM aged ≥ 18 years. Patients with moderate or severe aortic stenosis and those undergoing septal reduction were excluded. The significance level adopted in the statistical analysis was 5%.</p><p><strong>Results: </strong>The study included 1244 patients, between 2010 and 2022, with a mean follow-up time of 7.7 ± 4.5 years; 53.6% of patients were men. Mean age was 54.6 ± 16.5 years, and mean left ventricular ejection fraction (LVEF) was 65.8% ± 7.6. We observed LVEF ≤ 50% in 5.8% of patients, asymmetric form in 88.7%, and septal hypertrophy in 85.4%. We found systolic anterior motion of the mitral valve in 30.1% of patients, left ventricular outflow tract obstruction in 30.7%, and septum ≥ 28 mm in 7.2%. Only 1 patient had ventricular aneurysm. Atrial fibrillation/flutter occurred in 9.6% of patients. Overall mortality occurred in 232 patients (1.3%/year). Patients with B-type natriuretic peptide (BNP) > 200 pg/ml, left atrium ≥ 45 mm, and LVEF ≤ 50% had higher mortality (p < 0.001). Age and atrial fibrillation/flutter were also associated with mortality.</p><p><strong>Conclusions: </strong>The majority of patients had LVEF > 50%, asymmetric hypertrophy, and septal predominance. BNP, LA diameter, LVEF ≤ 50%, age, and atrial fibrillation/flutter were associated with worse prognosis.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 4","pages":"e20240640"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}