Maria Catarina de Melo Dias Guerra, André Gustavo da Silva Rezende, Tiago Augusto Magalhães, William Azem Chalela, Augusto Hiroshi Uchida, Rafael Almeida Fonseca, Nevelton Heringer Filho, Jürgen Beuther, Guilherme Garcia, Eduardo Cavalcanti Lapa Dos Santos, Ulisses Ramos Montarroyos, Renata Ávila Cintra, José Antônio Franchine Ramires, Carlos Eduardo Rochitte
{"title":"Detection and Location of Myocardial Infarction Using Electrocardiogram: Validation by Cardiovascular Magnetic Resonance Imaging.","authors":"Maria Catarina de Melo Dias Guerra, André Gustavo da Silva Rezende, Tiago Augusto Magalhães, William Azem Chalela, Augusto Hiroshi Uchida, Rafael Almeida Fonseca, Nevelton Heringer Filho, Jürgen Beuther, Guilherme Garcia, Eduardo Cavalcanti Lapa Dos Santos, Ulisses Ramos Montarroyos, Renata Ávila Cintra, José Antônio Franchine Ramires, Carlos Eduardo Rochitte","doi":"10.36660/abc.20240309","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>In the assessment of ischemic heart disease, cardiac magnetic resonance (CMR) is considered the gold standard for detecting and locating myocardial infarction (MI), but electrocardiogram (ECG) is less expensive and more widely available. Recognition of MI on ECG outside the acute phase is challenging; Q waves are absent in a significant proportion of patients and may reduce or disappear over time. Although ECG is widely used in the initial assessment of previous infarction, studies to validate ECG using CMR as a reference in the context of chronic coronary disease are limited.</p><p><strong>Objectives: </strong>To evaluate the diagnostic performance of ECG in detecting and locating CMR-defined MI.</p><p><strong>Methods: </strong>This study included 352 individuals who underwent CMR and ECG, 241 patients with previous MI confirmed by CMR and 111 controls with normal CMR. Their ECG tracings were analyzed by 2 observers, who were blinded to the CMR, for detection and location of MI following to the Fourth Brazilian Society of Cardiology Guidelines on the Analysis and Issuance of Electrocardiographic Reports. The significance level adopted was 5% (p < 0.05).</p><p><strong>Results: </strong>ECG showed good performance for detecting previous MI, with sensitivity of 69.3% (64.5% to 74.1%), specificity of 99.1% (98.1% to 100%), and accuracy of 78.7% (74.4% to 83.0%). However, in locating MI in accordance with CMR, its accuracy was unsatisfactory.</p><p><strong>Conclusions: </strong>When compared to CMR, ECG was shown to be a method with good accuracy for detecting previous MI, but not for defining its location.</p>","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 3","pages":"e20240309"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arquivos brasileiros de cardiologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36660/abc.20240309","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: In the assessment of ischemic heart disease, cardiac magnetic resonance (CMR) is considered the gold standard for detecting and locating myocardial infarction (MI), but electrocardiogram (ECG) is less expensive and more widely available. Recognition of MI on ECG outside the acute phase is challenging; Q waves are absent in a significant proportion of patients and may reduce or disappear over time. Although ECG is widely used in the initial assessment of previous infarction, studies to validate ECG using CMR as a reference in the context of chronic coronary disease are limited.
Objectives: To evaluate the diagnostic performance of ECG in detecting and locating CMR-defined MI.
Methods: This study included 352 individuals who underwent CMR and ECG, 241 patients with previous MI confirmed by CMR and 111 controls with normal CMR. Their ECG tracings were analyzed by 2 observers, who were blinded to the CMR, for detection and location of MI following to the Fourth Brazilian Society of Cardiology Guidelines on the Analysis and Issuance of Electrocardiographic Reports. The significance level adopted was 5% (p < 0.05).
Results: ECG showed good performance for detecting previous MI, with sensitivity of 69.3% (64.5% to 74.1%), specificity of 99.1% (98.1% to 100%), and accuracy of 78.7% (74.4% to 83.0%). However, in locating MI in accordance with CMR, its accuracy was unsatisfactory.
Conclusions: When compared to CMR, ECG was shown to be a method with good accuracy for detecting previous MI, but not for defining its location.