Archivos de la Sociedad Espanola de Oftalmologia最新文献

{"title":"Should XYY syndrome be considered in the differential diagnosis of syndromic myopia? Apropos of a case.","authors":"R Morales-Reyes, L A Garza-Garza, R A Villafuerte-de la Cruz, M Garza-Leon","doi":"10.1016/j.oftale.2025.08.005","DOIUrl":"10.1016/j.oftale.2025.08.005","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>XYY syndrome is relatively common and misdiagnosed. In addition high myopia appears to be more frequent in this syndrome than in the general population. Therefore, the objective of the present report is to emphasize the association of XYY syndrome and high myopia.</p><p><strong>Materials and methods: </strong>Case report of a single patient.</p><p><strong>Results: </strong>An 8-year-old male patient with a history of XYY syndrome was examined. Physical examination revealed tall stature, low-set auricular pavilion implantation, mid-face hypoplasia, horizontal palpebral fissures. Ophthalmological evaluation showed early-onset high myopia in both eyes and a complete nuclear cataract and chronic retinal detachment in the right eye.</p><p><strong>Discussion: </strong>Patients with XYY syndrome appear to exhibit a high prevalence of myopia. Although the pathophysiology of myopia in patients with XYY syndrome is not yet fully understood, it should be considered as a differential diagnosis for syndromic myopia.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravitreal Fluocinolone Acetonide Implant (ILUVIEN®) for the treatment of ocular juvenile xanthogranuloma.","authors":"M Larrañaga Cores, M Asencio Durán, J Peralta Calvo, M Feito Rodríguez, G Amorena Santesteban, A Del Hierro Zarzuelo, A Boto-de-Los-Bueis","doi":"10.1016/j.oftale.2025.08.002","DOIUrl":"10.1016/j.oftale.2025.08.002","url":null,"abstract":"<p><p>This is the case of a 14-years-old woman referred to our ophthalmology department with suspected iris juvenile xanthogranuloma, with reported bilateral, hematic recurrent uveitis as soon as she discontinued treatment with topical prednisolone acetate eye drops. After numerous treatments at the 3-year follow-up, including oral steroids, repeated injections of subtenon triamcinolone acetonide and intracameral and intravitreal anti-VEGF, treatment with intravitreal fluocinolone acetonide implant (ILUVIEN®) in both eyes was decided. Evolution since then and at the 10-month follow-up has been satisfactory; the patient has not exhibited any new episodes of ocular inflammation or hyphema despite the progressive withdrawal of topical corticosteroids, and vision has remained at 20/20 in both eyes. As far as we know, this is the first case of bilateral ocular juvenile xanthogranuloma successfully treated with an intravitreal fluocinolone implant.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal detachment associated to macular hole in nanophthalmos and high hyperopia.","authors":"A L Quiroz, P Armendariz, J D Grigera","doi":"10.1016/j.oftale.2025.08.004","DOIUrl":"10.1016/j.oftale.2025.08.004","url":null,"abstract":"<p><p>We report the case of a 74-year-old woman with high hyperopia and nanophthalmos who presented with a progressive central scotoma in her left eye. Best-corrected visual acuity was limited to hand motion, and examination revealed a full-thickness macular hole associated with retinal detachment. Pars plana vitrectomy with the inverted internal limiting membrane (ILM) flap technique and 20% sulfur hexafluoride (SF6) tamponade was performed, but hole closure was not achieved. A second surgery including phacovitrectomy, retinal massage and ILM flap repositioning resulted in successful anatomical closure and visual improvement. This case highlights the value of adjunctive techniques such as retinal massage and accurate ILM flap repositioning to promote closure in complex and uncommon scenarios.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute phase Vogt-Koyanagi-Harada syndrome resistant to corticosteroid therapy in an adult female patient.","authors":"Z E Kurt, M A Argin","doi":"10.1016/j.oftale.2025.08.003","DOIUrl":"10.1016/j.oftale.2025.08.003","url":null,"abstract":"<p><p>Vogt-Koyanagi-Harada (VKH) syndrome is a rare inflammatory disease that affects more than one system, including ophthalmological, auditory, cutaneous, and neurological systems. VKH syndrome is mostly characterized by panuveitis with serous retinal detachment, headache, hearing loss, vitiligo, and poliosis. Early diagnosis and proper management are crucial to prevent irreversible visual loss and other complications. We present a case report of VKH syndrome in a 29-year-old female patient. Initiation of corticosteroid therapy led to gradual regression of her symptoms. However, after cessation of corticosteroid therapy, the patient's visual acuity decreased, and the symptoms reappeared. Consequently, combination therapy with corticosteroid, azathioprine, and cyclosporine controlled the disease and stabilized clinical findings.This article highlights that early diagnosis and treatment of VKH syndrome with corticosteroid along with azathioprine and cyclosporine in the acute phase may improve a patient's quality of life and reduce the severity of the disease.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The spectrum of ophthalmologic abnormalities in MELAS is broader than expected.","authors":"J Finsterer","doi":"10.1016/j.oftale.2025.08.001","DOIUrl":"10.1016/j.oftale.2025.08.001","url":null,"abstract":"","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144786105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal imaging to detect retinal migration of perfluorocarbon liquid","authors":"F.J. Valentín Bravo ,&nbsp;K. Castaño Andrés ,&nbsp;X. Valldeperas","doi":"10.1016/j.oftale.2024.12.016","DOIUrl":"10.1016/j.oftale.2024.12.016","url":null,"abstract":"","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 8","pages":"Pages 508-509"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel KMT2D gene variant c.6341del (p.Gly2114Alafs*30) and its phenotypic presentation in a Hispanic-Mexican woman with Kabuki syndrome: A case report","authors":"L.A. Garza-Garza ,&nbsp;A.P. Arizpe ,&nbsp;R. Morales-Reyes ,&nbsp;R.A. Villafuerte-de la Cruz ,&nbsp;M. Garza-León","doi":"10.1016/j.oftale.2025.06.007","DOIUrl":"10.1016/j.oftale.2025.06.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Kabuki syndrome is a rare congenital malformation syndrome originally described by Niikawa et al. in 1981. A wide array of pathogenic variants and phenotypes have been described ever since. However, cases from Hispanic-Mexican populations evaluated with multimodal imaging are scarce. Therefore, the aim of this study is to report on the multimodal evaluation of a Hispanic-mexican case with a novel pathogenic variant.</div></div><div><h3>Materials and methods</h3><div>Next generation sequencing was used to search for pathogenic variants in KMT2D in the proband and her parents and sibling. A full systemic and ophthalmological examination along with ancillary studies were undertaken.</div></div><div><h3>Results</h3><div>Only the proband had relevant findings and a compatible pathogenic variant in KMT2D. The systemic and ophthalmic phenotype correlates with previous reports of Kabuki syndrome. Ancillary studies of the retina, optic nerve, macular area, macular vascular flow and cornea were within normal limits. The novel detected pathogenic variant in the proband was c.6341del (p.Gly2114Alafs*30) in KMT2D.</div></div><div><h3>Conclusions</h3><div>The present paper reports on a novel pathogenic variant in Kabuki syndrome. The multimodal imaging evaluation of the ophthalmic phenotype was within normal limits.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 8","pages":"Pages 452-457"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification of posterior staphyloma in pathologic myopia using 3D wide-field fundus imaging","authors":"J.D. Arias Aristizábal ,&nbsp;C.M. Cordoba-Ortega ,&nbsp;M.A. Gómez Velasco ,&nbsp;J.M. Barahona Campos","doi":"10.1016/j.oftale.2025.07.001","DOIUrl":"10.1016/j.oftale.2025.07.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Pathological myopia is associated with structural changes, including posterior staphylomas, which can be categorized based on their morphology. This study aims to classify posterior staphylomas in patients with pathological myopia using the 3D WIDE SCAN REVIEW Swept-Source optical coherence tomography (OCT) platform and compare the findings with the Ohno-Matsui classification.</div></div><div><h3>Patients and methods</h3><div>We conducted a retrospective cross-sectional cohort study, including 59 eyes from 31 patients diagnosed with high myopia (axial length<!--> <!-->≥<!--> <!-->26<!--> <!-->mm and/or spherical equivalent<!--> <!-->≥<!--> <!-->−6.00 diopters) and pathological myopia, defined as equal to or greater than diffuse chorioretinal atrophy or the presence of a posterior staphyloma, according to the META-PM study group. Posterior staphylomas were categorized based on fundus depression shape and appearance using 3D WIDE SCAN REVIEW analysis and compared using the Ohno-Matsui 2014 classification. Additionally, myopic maculopathy was assessed using the Atrophic-Tractional-Neovascular (ATN) classification, explicitly evaluating atrophic (A), tractional (T), and neovascular (N) components. Image acquisition was performed using the Topcon Triton Swept-Source OCT system, and images were processed and analyzed with the 3D WIDE SCAN REVIEW platform.</div></div><div><h3>Results</h3><div>The patients’ mean age was 49.56 years (SD<!--> <!-->±<!--> <!-->18.50; 71.05% women). The distribution of posterior staphylomas varied among the study population. Type I (wide macular) was the most prevalent, observed in 22.0% of cases, followed by Type II (narrow macular) at 10.2%, Type III (peripapillary) at 8.5%, Type IV (nasal) at 3.4%, and Type V (inferior) at 8.5%. This classification highlights the predominance of macular involvement in pathological myopia, with nasal and inferior staphylomas being less common. Regarding myopic maculopathy, A1 was the most common atrophic component (43.5%), T0 was predominant (78.3%), and N0 was the most common neovascular category (83%).</div></div><div><h3>Conclusions</h3><div>The 3D WIDE SCAN REVIEW Swept-Source OCT platform provides a high-resolution, non-invasive method for detailed visualization and classification of posterior staphylomas. By using Topcon Triton SS-OCT for image acquisition and 3D WIDE SCAN REVIEW software for analysis this study demonstrates a clinically viable alternative to traditional imaging modalities for evaluating posterior staphylomas in pathological myopia.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 8","pages":"Pages 458-465"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144621456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Safety Checklist in ophthalmology: A tertiary hospital proposal","authors":"N. Lorenzana-Blanco,&nbsp;A. Escudero-Villanueva,&nbsp;N. Alejandre-Alba,&nbsp;I. Jiménez-Alfaro Morote","doi":"10.1016/j.oftale.2025.05.014","DOIUrl":"10.1016/j.oftale.2025.05.014","url":null,"abstract":"<div><div>Adverse events due to unsafe healthcare practices constitute a serious global problem. The World Health Organization (WHO) has recognized healthcare insecurity as a public health issue and has undertaken various initiatives to safeguard patient safety. The Surgical Safety Checklist (SSC) is one of the tools implemented that has proven to be most effective in reducing morbidity and mortality associated with surgeries. Its impact is tied to implementation policies. Although the SSC is universal, the WHO has encouraged adaptations for different specialties. The purpose of our work is to present the SSC used in our hospital for major and minor ophthalmic surgery. Regarding cataract surgery, it is noteworthy to consider special ocular conditions and the correct choice of intraocular lens.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 8","pages":"Pages 466-472"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral and simultaneous retinal artery occlusion in a woman with systemic lupus erythematosus","authors":"V.M. Asensio-Sánchez","doi":"10.1016/j.oftale.2025.04.012","DOIUrl":"10.1016/j.oftale.2025.04.012","url":null,"abstract":"<div><div>Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect almost every organ. This article describes a middle-aged woman, previously diagnosed with untreated SLE, who during a severe SLE flare simultaneously presented with a superior nasal artery occlusion in the right eye and a central retinal artery occlusion (CRAO) in the left eye. Severe ocular complications, such as CRAO, can occur during an acute flare of the disease in previously asymptomatic SLE.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 8","pages":"Pages 473-475"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}