Archivos de la Sociedad Espanola de Oftalmologia最新文献_第5页

Lacrimal gland carcinoma with apocrine differentiation: Literature review about a case 泪腺癌伴大汗腺分化1例文献复习。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-09-01 Epub Date: 2026-05-01 DOI: 10.1016/j.oftale.2026.502540

A. Astobieta Odriozola, R. Casas Cornejo, J. Cacicedo Fernández de Bobadilla, J. Alonso Fernandez, A. Amías Gorostiza, R. Medel Jiménez

引用次数: 0

Paid work leave for cataract surgery companions: Legal issues 白内障手术同伴带薪休假：法律问题。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-09-01 Epub Date: 2026-03-06 DOI: 10.1016/j.oftale.2026.502454

M. Sanchidrián

引用次数: 0

Therapeutic applications of gene editing using CRISPR-Cas9 in the posterior segment: review of the literature CRISPR-Cas9在后段基因编辑的治疗应用：文献综述

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-09-01 Epub Date: 2026-06-12 DOI: 10.1016/j.oftale.2026.502582

J.A. Leon Agudelo, H. Martínez Vallejo

引用次数: 0

Lenticular pseudohypopyon in a Morgagnian cataract. 摩根型白内障的透镜状假低视。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-08-24 DOI: 10.1016/j.oftale.2026.502653

R K Jha, S Seth, J Kaushik

引用次数: 0

Nutrition and microbiota in ocular surface and dry eye disease. 眼表营养和微生物群与干眼症。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-08-23 DOI: 10.1016/j.oftale.2026.502652

C Vergés-Roger, I Andrés-Blasco, J Salgado-Borges, M Cerdá-Ibáñez, V Zanón-Moreno, S Mora-Sáez

{"title":"Nutrition and microbiota in ocular surface and dry eye disease.","authors":"C Vergés-Roger, I Andrés-Blasco, J Salgado-Borges, M Cerdá-Ibáñez, V Zanón-Moreno, S Mora-Sáez","doi":"10.1016/j.oftale.2026.502652","DOIUrl":"10.1016/j.oftale.2026.502652","url":null,"abstract":"Nutrition plays a crucial role in the prevention and management of dry eye disease (DED. Polyunsaturated fatty acids ω-3 and ω-6, known for their anti-inflammatory properties, improve ocular surface health. Similarly, antioxidants found in diets like the Mediterranean diet stabilize the tear film and reduce oxidative stress (OXs); however, food additives can negatively impact both general health and DED. The gut microbiome and the gut-eye axis play a critical role, as gut dysbiosis amplifies systemic inflammation, disrupts immune balance, and diminishes the production of protective metabolites such as short-chain fatty acids. The ocular microbiome further supports homeostasis and immunity by safeguarding against external pathogens. Factors such as diet, aging, and antibiotic use negatively impact microbial diversity. Probiotics, prebiotics, and fecal microbiota transplantation are emerging microbiota-targeted strategies for dry eye disease. However, current evidence remains limited and is largely based on preclinical and preliminary clinical studies, highlighting the need for further controlled investigations to better define their therapeutic role and clinical applicability.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":"502652"},"PeriodicalIF":0.0,"publicationDate":"2026-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148809593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bringing clarity to the clinical framework for photic phenomena and dysphotopsias through the evidence-based functional classification: a narrative review. 通过循证功能分类使光现象和光功能障碍的临床框架清晰：叙述性回顾。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-08-23 DOI: 10.1016/j.oftale.2026.502648

F Ribeiro, H B Dick, D Koch, M Rodríguez-Vallejo, J Fernández

{"title":"Bringing clarity to the clinical framework for photic phenomena and dysphotopsias through the evidence-based functional classification: a narrative review.","authors":"F Ribeiro, H B Dick, D Koch, M Rodríguez-Vallejo, J Fernández","doi":"10.1016/j.oftale.2026.502648","DOIUrl":"10.1016/j.oftale.2026.502648","url":null,"abstract":"This narrative review aimed to explore the evidence on photic phenomena (PP) and positive dysphotopsia (PD) associated with simultaneous vision intraocular lenses (SVIOLs), with particular emphasis on refractive lens exchange (RLE) and the functional classification framework. A structured PubMed search identified systematic reviews and meta-analyses reporting PP/PD outcomes, and these findings were integrated with stratified analyses from the IOLEvidence database, restricted to standard, non-toric IOL studies in populations without comorbidities. Evidence syntheses consistently indicate lower rates of halos and dysphotopsia with monofocal and enhanced monofocal IOLs and higher frequencies with Full-DOFi designs, although heterogeneity and inconsistent PP/PD definitions limit pooled inferences. Category-based analyses suggest that Narrowed and Enhanced lenses show lower halo frequency than Full-DOFi lenses, while Extended designs demonstrate intermediate outcomes with substantial overlap. Within-category variability, particularly in the Extended group, indicates that optical design (refractive versus diffractive) may influence PP/PD more strongly than the achieved DOFi. Stratified analyses using IOLEvidence enable earlier, model-specific comparisons that anticipate clinically relevant differences before conventional meta-analyses detect them. In RLE, where preoperative lens clarity and patient expectations differ from cataract populations, preoperative symptom assessment and objective optical-quality metrics might be critical to manage postoperative dysphotopsia patient expectations.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":"502648"},"PeriodicalIF":0.0,"publicationDate":"2026-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148809595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurovascular unit-targeted therapeutic strategies in diabetic retinopathy. 糖尿病视网膜病变的神经血管单元靶向治疗策略。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-08-22 DOI: 10.1016/j.oftale.2026.502655

S Fragiotta, C Ciancimino, G Scuderi

{"title":"Neurovascular unit-targeted therapeutic strategies in diabetic retinopathy.","authors":"S Fragiotta, C Ciancimino, G Scuderi","doi":"10.1016/j.oftale.2026.502655","DOIUrl":"10.1016/j.oftale.2026.502655","url":null,"abstract":"Diabetic retinopathy (DR) has traditionally been regarded as a microvascular complication, but increasing evidence supports its classification as a neurovascular disease. The retinal neurovascular unit (NVU), comprising neurons, glial, and vascular, elements, is crucial for retinal homeostasis and is disrupted early in DR. The present narrative review aims to summarize current clinical evidence on the role of NVU dysfunction in DR and to evaluate the clinical benefits of NVU-oriented therapeutic strategies. Clinical data indicate that neurodegeneration and glial activation, precede overt blood-retinal barrier damage and microvascular breakdown observable in DR. Emerging NVU-oriented treatments, including topical neuroprotective agents, anti-inflammatory therapies, and selected systemic metabolic drugs, show beneficial effects on functional and structural retinal outcomes. Targeting NVU may represent a disease-modifying strategy, enabling earlier intervention and potentially preventing irreversible vision loss in DR. Further well-designed prospective and randomized studies are warranted to strengthen the level of evidence and validate this therapeutic approach.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":"502655"},"PeriodicalIF":0.0,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adjunct rose Bengal photodynamic antimicrobial therapy for refractory Pseudomonas aeruginosa infectious necrotizing scleritis after scleral buckling: a case report. 辅助玫瑰孟加拉光动力抗菌治疗巩膜屈曲后难治性铜绿假单胞菌感染性坏死性巩膜炎1例。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-08-22 DOI: 10.1016/j.oftale.2026.502654

A Botero-Benítez, G R Vera-Duarte, M Muleiro-Alvarez, N Kahuam-López, A Ramirez-Miranda, A Navas, E O Graue-Hernandez, R Eskenazi-Betech

{"title":"Adjunct rose Bengal photodynamic antimicrobial therapy for refractory Pseudomonas aeruginosa infectious necrotizing scleritis after scleral buckling: a case report.","authors":"A Botero-Benítez, G R Vera-Duarte, M Muleiro-Alvarez, N Kahuam-López, A Ramirez-Miranda, A Navas, E O Graue-Hernandez, R Eskenazi-Betech","doi":"10.1016/j.oftale.2026.502654","DOIUrl":"10.1016/j.oftale.2026.502654","url":null,"abstract":"A 34-year-old man developed rapidly progressive infectious necrotizing scleritis following blunt ocular trauma and subsequent scleral buckle placement for rhegmatogenous retinal detachment. At presentation, best-corrected visual acuity was light perception, with conjunctival lysis, multifocal scleral thinning with uveal exposure, purulent discharge, and marked ocular inflammation. Microbiologic cultures grew Pseudomonas aeruginosa. Despite targeted topical and systemic antimicrobial therapy and surgical debridement with partial buckle removal and tectonic reconstruction, scleral necrosis continued to progress. RB-PDAT was performed as adjuvant therapy, resulting in rapid clinical improvement, stabilization of scleral thinning, resolution of purulence and active inflammation, and no further tissue loss during follow-up. RB-PDAT may be a useful adjunctive option for refractory infectious necrotizing scleritis, particularly in aggressive Pseudomonas infections when conventional medical and surgical measures fail to halt scleral melt.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":"502654"},"PeriodicalIF":0.0,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent intraocular inflammation: Staphylococcus hominis endophthalmitis. 复发性眼内炎症：人性葡萄球菌眼内炎。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-08-22 DOI: 10.1016/j.oftale.2026.502632

M P González de Frutos, G Garrido Ceca, J J González Guijarro

{"title":"Recurrent intraocular inflammation: Staphylococcus hominis endophthalmitis.","authors":"M P González de Frutos, G Garrido Ceca, J J González Guijarro","doi":"10.1016/j.oftale.2026.502632","DOIUrl":"10.1016/j.oftale.2026.502632","url":null,"abstract":"An 84-year-old highly myopic monocular male, with remote uncomplicated extracapsular cataract surgery without intraocular lens implantation and chronic inflammatory eyelid disease, presented with presumed mild bacterial keratitis (BK), whitish retroiridian masses and associated moderate panuveitis in his right eye. Corneal and aqueous humour cultures, as well as an extensive systemic septic work-up, were negative. Combined treatment with fortified topical, intravitreal and parenteral antibiotics, together with systemic corticosteroids, achieved rapid and complete resolution. Seven months later, the same clinical picture recurred; despite prompt remission after retreatment, pars plana vitrectomy was added. No relapses occurred during 3 years of follow-up. Staphylococcus hominis was isolated from the removed whitish masses. Possible pathogenic mechanisms include bacterial sequestration within capsular remnants, recurrent culture-negative presumed BK, or even sample contamination, potentially facilitated by bacterial permanence and persistence on the ocular surface. Identification of S. hominis as a potential cause of intraocular inflammation remains exceedingly uncommon, with only a few cases reported.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":"502632"},"PeriodicalIF":0.0,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of presbyopic patients with previous corneal refractive surgery: Phenotype-driven considerations and functional classification. 老花眼患者既往角膜屈光手术的处理：表型驱动的考虑和功能分类。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2026-08-22 DOI: 10.1016/j.oftale.2026.502647

M Rodriguez-Calvo-de-Mora, C Rocha-de-Lossada, M Rodríguez-Vallejo, J Fernández

{"title":"Management of presbyopic patients with previous corneal refractive surgery: Phenotype-driven considerations and functional classification.","authors":"M Rodriguez-Calvo-de-Mora, C Rocha-de-Lossada, M Rodríguez-Vallejo, J Fernández","doi":"10.1016/j.oftale.2026.502647","DOIUrl":"10.1016/j.oftale.2026.502647","url":null,"abstract":"Purpose: To review the available evidence on simultaneous-vision intraocular lens (SVIOL) implantation in eyes with previous corneal refractive surgery (CRS), considering the interaction between corneal phenotype and the functional depth-of-field (DOFi) classification of intraocular lenses.Methods: Narrative literature review evaluating clinical outcomes of SVIOL implantation in eyes with prior CRS, including myopic and hyperopic LASIK/PRK, SMILE, and radial keratotomy. Full-DOFi and Partial-DOFi lenses were compared regarding refractive predictability, visual quality, spectacle independence, and sensitivity to residual aberrations.Results: Refractive predictability remained lower in post-CRS eyes, particularly after hyperopic ablations and radial keratotomy. Full-DOFi lenses provided superior near vision and higher spectacle independence rates in selected myopic LASIK eyes, although they appeared more sensitive to residual aberrations. Evidence regarding Partial-DOF lenses mainly derives from extended-depth-of-focus and multifocal designs, with limited data for other subclasses. Available studies suggest greater optical tolerance and a lower burden of photic phenomena, potentially at the expense of near visual performance, but the evidence is limited. Evidence in SMILE and radial keratotomy remains scarce and heterogeneous.Conclusions: Careful patient selection based on corneal phenotype and comprehensive preoperative assessment are essential in post-CRS patients. Biometric predictability remains the main limiting factor in optimizing refractive outcomes with SVIOL implantation.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":"502647"},"PeriodicalIF":0.0,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0