Archivos de la Sociedad Espanola de Oftalmologia最新文献_第4页

Retinal angiomatous proliferation and pachychoroid. 视网膜血管瘤增生和厚脉络膜。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-21 DOI: 10.1016/j.oftale.2025.05.011

J L Sánchez-Vicente, E M Gámez-Jiménez, J C Fernández-Fontán, F J Cordero-Bellido, J Suárez-Pérez, F López-Herrero

引用次数: 0

Topical permethrin 5% as a treatment for pediatric patients with phthiriasis palpebrarum: A case report. 5%氯菊酯外用治疗小儿上睑皮炎1例。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-10 DOI: 10.1016/j.oftale.2025.05.008

J Noguera Campos, S Pose Bazarra, N Castro Casal, A Urbano Bueno, M D Álvarez Díaz

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New OCT sign in X-linked retinoschisis without macular schisis: "Inverted roof fovea". 无黄斑裂片的x联性视网膜裂片的OCT新征象：“倒顶中央凹”。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-09 DOI: 10.1016/j.oftale.2025.05.003

P B Blasco Palacio, A Aramburu-Gonzalez, I Rodríguez García

引用次数: 0

XEN 63 in a case of refractory glaucoma secondary to microphthalmia and aphakia xen63继发于小眼和无晶状体的难治性青光眼1例。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.010

S. Labay-Tejado , J. Laguna , M.J. Navarro-Angulo , L. Muñoz , M. Jodar , E. Milla

{"title":"XEN 63 in a case of refractory glaucoma secondary to microphthalmia and aphakia","authors":"S. Labay-Tejado , J. Laguna , M.J. Navarro-Angulo , L. Muñoz , M. Jodar , E. Milla","doi":"10.1016/j.oftale.2025.03.010","DOIUrl":"10.1016/j.oftale.2025.03.010","url":null,"abstract":"<div><div>Microphthalmia (MO) predisposes to glaucoma and congenital cataracts (CC). Cataract removal in MO is characterized by several complications such as aphakic glaucoma (AG).</div><div>We report the case of a 33-year-old male with MO, aphakia, and refractory glaucoma who underwent inferonasal ab-interno XEN 63 implantation, after posterior vitrectomy. Whole Exome Sequencing (WES) analysis was performed identifying the likely pathogenic variant c.197G>A (p.Cys66Tyr) in heterozygosity in the <em>PAX6</em> gene related to Peters anomaly (PA) and the variant of unclear significance c.353T>C (p.Leu118Pro) in heterozygosity in the <em>CRYBB3</em> gene, potentially related to CC. Until the 12-month follow-up, the patient maintained intraocular pressure (IOP) between 16 and 18 mmHg without medication or complications.</div><div>XEN 63, when combined with posterior vitrectomy may be an option in select cases, owing to its versatility. However, further investigation is required. Genetic analysis provides a pre-symptomatic diagnosis and may lead to a more personalised medicine.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 289-294"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endothelial changes in patients with and without diabetes after manual small-incision cataract surgery 糖尿病患者和非糖尿病患者手工小切口白内障术后内皮细胞的变化。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.016

L.A. Oseguera Chávez, L.E. Salas Medina, C. Palacio Pastrana, W. Cedillo Suárez

{"title":"Endothelial changes in patients with and without diabetes after manual small-incision cataract surgery","authors":"L.A. Oseguera Chávez, L.E. Salas Medina, C. Palacio Pastrana, W. Cedillo Suárez","doi":"10.1016/j.oftale.2025.03.016","DOIUrl":"10.1016/j.oftale.2025.03.016","url":null,"abstract":"<div><h3>Background and objective</h3><div>In Mexico there is a high prevalence of diabetes, which is one of the most frequent etiologies of cataract. The impact of diabetes on postoperative corneal decompensation associated with MSICS has not been studied in our country. The objective of the study was to determine the difference in corneal endothelial changes between diabetic and non-diabetic patients by preoperative specular microscopy and at one month and 3 months after MSICS.</div></div><div><h3>Patients and methods</h3><div>Prospective, longitudinal, paired, non-randomized study with two groups; Group 1: diabetic patients and Group 2: non-diabetic patients. All patients had a complete ophthalmologic evaluation and preoperative and postoperative specular microscopy at one month and 3 months.</div></div><div><h3>Results</h3><div>119 eyes were included. The percentage of CD loss at 1 month was 11.1% in diabetic patients and 6.3% in non-diabetic patients. At 3 months the percentage of loss was 9.9% in diabetic patients and 5.4% in non-diabetic patients. The CV was higher in patients with diabetes and was significant at 1 month; however, at 3 months the values were comparable. The percentage of HEX decreased significantly in the first month in patients with diabetes.</div></div><div><h3>Conclusions</h3><div>There was a significant difference with greater CD loss, greater CV and less HEX in patients with diabetes vs. without diabetes at 1 month after the M-SICS procedure, however, it was not statistically significant at 3 months. This suggests greater endothelial stress, longer recovery time and remodeling of the corneal endothelium in patients with diabetes.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 246-253"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the Enigma: Gigantic primary de novo poorly-differentiated ductal adenocarcinoma of the lacrimal gland with aggressive features. A case report and literature review 揭开谜团：巨大的原发性泪腺低分化导管腺癌，具有侵袭性特征。病例报告及文献复习。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.018

S. Malik, C. Ahluwalia, A. Aziz Khan

{"title":"Unveiling the Enigma: Gigantic primary de novo poorly-differentiated ductal adenocarcinoma of the lacrimal gland with aggressive features. A case report and literature review","authors":"S. Malik, C. Ahluwalia, A. Aziz Khan","doi":"10.1016/j.oftale.2025.03.018","DOIUrl":"10.1016/j.oftale.2025.03.018","url":null,"abstract":"<div><div>Primary ductal adenocarcinoma (PDA) of the lacrimal gland is a rare and aggressive malignancy originating from ductal epithelial cells. Its rarity and diverse clinical presentations pose significant diagnostic challenges, emphasizing the need for accurate diagnosis and appropriate management strategies. The study presents an intriguing case of a 50-year-old man with a large de novo primary ductal adenocarcinoma of the lacrimal gland, initially misdiagnosed as a meningeal solitary fibrous tumor due to its atypical clinical presentation of “down and out” proptosis. The case underscores the importance of histopathology to achieve a correct diagnosis and guide management decisions. Despite aggressive treatment approaches, the prognosis of primary ductal adenocarcinoma patients remains grim due to its aggressive behavior and tendency for recurrence and metastasis. The present case study emphasizes that a differential of primary ductal adenocarcinoma should be considered despite the presence of anomalous clinical and radiological presentation.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 295-301"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serious incidents involving ocular medical devices reported to the AEMPS 向AEMPS报告的涉及眼科医疗器械的严重事故。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.008

L.C. Ramón-Carreira , E.M. Sobas , J.C. Pastor

引用次数: 0

Williams-Beuren syndrome case series with thinner fovea centralis and central corneal thicknesses Williams-Beuren综合征的病例系列与较薄的中央凹和角膜中央厚度。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.01.012

G. Yılmaz , G. Demirci , S. Karaman , M. Sargolzaeimoghaddam , E.S. Uluçam , A. Sarg

{"title":"Williams-Beuren syndrome case series with thinner fovea centralis and central corneal thicknesses","authors":"G. Yılmaz , G. Demirci , S. Karaman , M. Sargolzaeimoghaddam , E.S. Uluçam , A. Sarg","doi":"10.1016/j.oftale.2025.01.012","DOIUrl":"10.1016/j.oftale.2025.01.012","url":null,"abstract":"<div><h3>Background/aims</h3><div>To characterize the ocular signs of Williams-Beuren syndrome (WBS) in 3 cases examined at XXX University Ophthalmology Clinic.</div></div><div><h3>Methods</h3><div>Three patients with a diagnosis of WBS underwent comprehensive ophthalmic evaluation at the XXX University Ophthalmology, including best-corrected visual acuity, slitlamp biomicroscopy, dilated fundus examination, optical coherence tomography, corneal topography and colour fundus imaging.</div></div><div><h3>Results</h3><div>All 3 cases had decreased best corrected visual acuity, decreased ILM-RNFL thicknesses with a persistence of inner retinal layers on the SD-OCT examinations, decreased central corneal thickness yet normal epithelial thickness measurements and retinal arteriolar tortuosity in fundus examination.</div></div><div><h3>Conclusion</h3><div>WBS is a complex multisystem genetic disorder. The ocular findings observed in these cases which are decreased corneal thickness with normal epithelial thickness, decreased ILM-RPE thicknesses, and retinal arteriolar tortuosity may provide future insight into systemic vascular findings affected by a microdeletion of chromosome 7q11.23 which also contains elastin gene in WBS.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 238-245"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma 细胞因子分析评价原发性开角型青光眼和剥脱性青光眼的严重程度。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.019

L. Gallardo Martin , B. Burgos-Blasco , B. Vidal-Villegas , J.I. Fernandez-Vigo , J. Garcia-Feijoo , J.M. Martinez-de-la-Casa

{"title":"Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma","authors":"L. Gallardo Martin , B. Burgos-Blasco , B. Vidal-Villegas , J.I. Fernandez-Vigo , J. Garcia-Feijoo , J.M. Martinez-de-la-Casa","doi":"10.1016/j.oftale.2025.03.019","DOIUrl":"10.1016/j.oftale.2025.03.019","url":null,"abstract":"<div><h3>Purpose</h3><div>To analyze cytokines in tear and aqueous humour as biomarkers for evaluation of severity of glaucoma.</div></div><div><h3>Design</h3><div>Cross-sectional study.</div></div><div><h3>Subjects and methods</h3><div>Tear and aqueous humour samples were collected from 15 exfoliative glaucoma (XFG) patients, 43 primary open-angle glaucoma (POAG) patients and 33 controls (eligible for cataract surgery).</div><div>A total of 27 inflammatory cytokines were analyzed in the tear and aqueous humor samples by the Bio-Plex Pro Human Cytokine 27-Plex Immunoassay kit: interleukin (IL)-1b, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL9, IL-10, IL-12, IL-13, IL-15, IL-17, eotaxin, fibroblast growth factor (FGF) basic, granulocyte colony-stimulating factor, granulocyte-monocyte colony-stimulating factor, interferon-γ, interferon gamma-induced protein, monocyte chemo-attractant protein-1, macrophage inflammatory protein (MIP)-1a, MIP-1b, platelet-derived growth factor, regulated on activation normal T cell expressed and secreted, tumor necrosis factor-α and vascular endothelial growth factor.</div></div><div><h3>Results</h3><div>In the tear samples a statistically significant difference in Il-2, IL-4, IL-9, IL-12, IL-15 and FGF-basic between study groups was observed. In aqueous humor, a statistically significant difference of the following cytokines was observed: IL-5, IL-6, IL-12 and MCP-1. Il-4 and IL-15 differences correlate with the number of topical drugs, while IL-9 and IL-15 are associated with the visual field mean defect.</div></div><div><h3>Conclusion</h3><div>Inflammation is strongly associated with glaucoma and some cytokines may be related to glaucoma severity.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 254-263"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation 视网膜病变伴面肩肱肌营养不良。玻璃体内植入地塞米松联合激光光凝治疗1例。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.014

A.B. González Escobar, I.E. Molina Guilabert, R.M. García Herrera, I.M. Baquero Aranda, R. Luque Aranda, J.M. Galván Cano

{"title":"Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation","authors":"A.B. González Escobar, I.E. Molina Guilabert, R.M. García Herrera, I.M. Baquero Aranda, R. Luque Aranda, J.M. Galván Cano","doi":"10.1016/j.oftale.2025.03.014","DOIUrl":"10.1016/j.oftale.2025.03.014","url":null,"abstract":"<div><div>Facioscapulohumeral muscular dystrophy (FSHD) is a slowly progressive muscular dystrophy that affects especially the muscles of the face, shoulder girdle and upper arms. It may present extramuscular manifestations such as hearing loss and retinopathy. Up to 75% of patients may show alterations in the retinal vasculature such as vascular tortuosity, microaneurysms, telangiectasias, retinal ischemia and exudation, and in less than 1% of cases it may present as Coats-like syndrome. We present a 40-year-old male with FSHD who, in an ophthalmologic examination, showed exudative retinopathy in his left eye (LE) with peripheral retinal ischemia treated with laser therapy, and macular edema (ME) treated with intravitreal dexamethasone injection (IDI).</div><div>We would like to emphasize the importance of performing an ophthalmological examination on all patients with FSHD to rule out associated retinal pathology, and thus prevent loss of visual acuity (VA) with early treatment.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 283-288"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0