Archivos de la Sociedad Espanola de Oftalmologia最新文献_第4页

Evaluation of the effectiveness of Ahmed's valve implantation adding mitomicin C in patients with refractory glaucoma after one year of follow-up 加入肌霉素c的艾哈迈德瓣膜植入物在难治性青光眼患者随访一年的疗效评价。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.07.008

O. Teherán , C. Parra , E. Ramos , M. Ochoa , W. Escobar

{"title":"Evaluation of the effectiveness of Ahmed's valve implantation adding mitomicin C in patients with refractory glaucoma after one year of follow-up","authors":"O. Teherán , C. Parra , E. Ramos , M. Ochoa , W. Escobar","doi":"10.1016/j.oftale.2025.07.008","DOIUrl":"10.1016/j.oftale.2025.07.008","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the effectiveness and safety of mitomycin C (MMC) use when implanting Ahmed valve in patients with refractory glaucoma.</div></div><div><h3>Methods</h3><div>Cohort study involving 34 patients divided into two groups of 17 patients each: Group 1 (MMC use) and Group 2 (no MMC use), with a one-year follow-up. Complete success was defined as intraocular pressure (IOP) between 6−18 mmHg without the use of antiglaucoma medications; qualified success referred to the same IOP range but associated with antiglaucoma medications, while failure was characterized by IOP outside this range, severe complications or reintervention.</div></div><div><h3>Results</h3><div>The overall success rate in Group 1 was 88.2%, and in Group 2, 94.2%. There was an average reduction in IOP of 18.0-± 11.5 mmHg in Group 1 and 11.3 ± 5.0 mmHg in Group 2. The hypertensive phase occurred in 17.6% of the participants in the first group and the second, 70.6%.</div></div><div><h3>Conclusions</h3><div>The use of MMC decreases the hypertensive phase observed in Ahmed valve implant surgery, thereby achieving better IOP control.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 9","pages":"Pages 521-527"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis of bilateral idiopathic choroidal folds by funduscopy, OCT, and orbital ultrasound 眼底镜、OCT及眼眶超声诊断双侧特发性脉络膜皱褶。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.06.005

E. Gracia-Rovira, L. Manfreda Dominguez, A.-M. Duch Samper

引用次数: 0

Retinal angiomatous proliferation and pachychoroid 视网膜血管瘤增生和厚脉络膜。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.05.011

J.L. Sánchez-Vicente, E.M. Gámez-Jiménez, J.C. Fernández-Fontán, F.J. Cordero-Bellido, J. Suárez-Pérez, F. López-Herrero

引用次数: 0

Atypical endophthalmitis by Streptococcus pneumonia 由肺炎链球菌引起的不典型眼内炎。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.07.003

M. Moro-Muniz , J. Raga Cervera , G. Genovés , A. Adloff-Alonso , A. Janicka-Caulineau , D. Salom

{"title":"Atypical endophthalmitis by Streptococcus pneumonia","authors":"M. Moro-Muniz , J. Raga Cervera , G. Genovés , A. Adloff-Alonso , A. Janicka-Caulineau , D. Salom","doi":"10.1016/j.oftale.2025.07.003","DOIUrl":"10.1016/j.oftale.2025.07.003","url":null,"abstract":"<div><div>Endogenous endophthalmitis is a serious intraocular infection resulting from hematogenous spread of microorganisms. Although <em>Streptococcus pneumoniae</em> is an uncommon cause, its aggressiveness can lead to severe complications.</div><div>We present the case of a 48-year-old male who presented to the emergency department with blurred vision and periorbital pain in the right eye. Examination revealed hypertensive panuveitis with vitreous hemorrhage. Broad-spectrum topical and systemic antibiotics were initiated.</div><div>Imaging studies showed signs of orbital cellulitis without venous thrombosis, and aqueous humor culture confirmed the presence of <em>S. pneumoniae</em>, prompting hospital admission. Despite treatment, clinical progression led to the development of an intraorbital abscess requiring evisceration, after which the patient evolved favorably, allowing for later prosthesis placement.</div><div>This case highlights the aggressiveness of pneumococcal endogenous endophthalmitis and the importance of early, multidisciplinary management.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 9","pages":"Pages 553-557"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral corneal ulcer due to K. oxytoca: A case report 双侧角膜溃疡1例。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.07.006

L.M. Mora-Peñuela , J. Tirado-Ángel , M.A. Martínez-Ceballos

{"title":"Bilateral corneal ulcer due to K. oxytoca: A case report","authors":"L.M. Mora-Peñuela , J. Tirado-Ángel , M.A. Martínez-Ceballos","doi":"10.1016/j.oftale.2025.07.006","DOIUrl":"10.1016/j.oftale.2025.07.006","url":null,"abstract":"<div><div>Bacterial keratitis is one of the leading causes of monocular blindness worldwide. The following case describes the case of a patient with bilateral bacterial keratitis caused by <em>Klebsiella oxytoca</em>, a gram-negative bacterium often overlooked in cases of bacterial infectious keratitis. The patient is a 20-year-old man with a past medical history of allergic keratoconjunctivitis and keratoconus who developed an epithelial defect following improper handling of his contact lenses. Initially, the patient was managed with ocular lubricants. However, he experienced a rapid and aggressive deterioration in visual acuity, with an expansion of the epithelial defect and the appearance of bilateral stromal infiltrates. Due to the poor response to empirical antimicrobial therapy, cultures were obtained from the contact lenses, which identified the presence of <em>K. oxytoca</em> as the causative agent. The antibiogram revealed resistance to widely used antibiotics such as ciprofloxacin. Following these results, targeted antimicrobial therapy was initiated, leading to significant clinical improvement and substantial anatomical and visual recovery. This case underscores the importance of recognizing the potential aggressiveness of <em>K. oxytoca</em> in immunocompetent patients, which can cause severe ocular infections, particularly in individuals with risk factors such as contact lens wear. It also highlights the critical need for microbiological cultures and antibiograms to guide effective therapy, given the variable resistance patterns of this microorganism.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 9","pages":"Pages 563-570"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ambispective study on the phenotypic progression of patients with Stargardt disease associated with ABCA4 gene mutations 与ABCA4基因突变相关的Stargardt病患者表型进展的双透视研究

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.07.012

V.A. Martel Ramirez, C.R. Pérez Montaño, A.Y. Hernández Vázquez, S. Rojas Juárez, J.A. Ramírez Estudillo

{"title":"Ambispective study on the phenotypic progression of patients with Stargardt disease associated with ABCA4 gene mutations","authors":"V.A. Martel Ramirez, C.R. Pérez Montaño, A.Y. Hernández Vázquez, S. Rojas Juárez, J.A. Ramírez Estudillo","doi":"10.1016/j.oftale.2025.07.012","DOIUrl":"10.1016/j.oftale.2025.07.012","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to describe the phenotypic progression of patients with Stargardt disease caused by mutations in the <em>ABCA4</em> gene and reports on the mutated allelic variants.</div></div><div><h3>Method</h3><div>We conducted an observational, ambispective, and descriptive study. Patients who had Stargardt disease by the <em>ABCA4</em> gene mutation were included. The study used the genetic report and the baseline examinations appearing on health records. To evaluate the phenotypic variation, a new ophthalmological evaluation was conducted using macular OCT, retinography, autofluorescence, and electroretinogram.</div></div><div><h3>Results</h3><div>The study identified a total of 32 cases with a mean follow-up of 6 years. The mean age of onset was 16 years. The mean initial and final VA were 0.79 and 0.95 logMAR, respectively. The mean initial and final CMT were 142.5 and 135 microns, respectively. The predominant degree of fundus involvement and autofluorescence pattern at the beginning and end was macular atrophy with flecks and the low signal of macular autofluorescence surrounded by a heterogeneous background, respectively. Initial electroretinography showed predominantly preserved function of rods and cones, while in the end most cases presented rod and cone system dysfunction. A total of 9 cases were homozygous, and 31 different mutant allelic variants were identified. The most common variant was p.Trp1618Cys, followed by p.Ala1773Val. Two new allelic variants, p.Leu634Pro, and p.Tyr665Serfs*5, were also discovered.</div></div><div><h3>Conclusions</h3><div>The study found that patients experienced structural and functional deterioration at the follow-up. The study also identified 2 predominant variants and 2 new variants. Homozygotes had an earlier onset of the disease.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 9","pages":"Pages 528-536"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144736040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential characteristics in high myopia with and without glaucoma 高度近视伴与不伴青光眼的鉴别特征。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.07.011

P. Robles Amor , A. Cabo Sánchez , A. Antón López , S. Duch Tuesta , J. Moreno Montañés , F.J. Muñoz Negrete , I. Rodríguez Uña , F. Sáenz Francés , J. García Feijoó , J.M. Martínez de la Casa

{"title":"Differential characteristics in high myopia with and without glaucoma","authors":"P. Robles Amor , A. Cabo Sánchez , A. Antón López , S. Duch Tuesta , J. Moreno Montañés , F.J. Muñoz Negrete , I. Rodríguez Uña , F. Sáenz Francés , J. García Feijoó , J.M. Martínez de la Casa","doi":"10.1016/j.oftale.2025.07.011","DOIUrl":"10.1016/j.oftale.2025.07.011","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>To identify the differences in ocular and epidemiological parameters between highly myopic subjects with and without glaucoma.</div></div><div><h3>Material and methods</h3><div>A total of 386 patients diagnosed with high myopia were recruited in hospital consultations from October 2022 through October 2023. High myopia was defined as an axial length ≥26 mm and/or a refractive error ≥−6 diopters of sphere. We perform a complete ophthalmological examination, incorporating optical biometry to measure axial length and an objective refraction to quantify refractive error.</div></div><div><h3>Results</h3><div>386 high myopic patients without (Group I: n = 138) and with glaucoma (Group II: n = 248) who attended for consultation were included in the study. The distribution by sex was similar in both groups.</div><div>The mean age was slightly higher in the glaucoma group than in the subjects without glaucoma, without finding statistically significant differences (63.8 vs 62.4 years; p = 0.349).</div><div>Patients with glaucoma had a higher mean refractive error: −15.52 diopters vs −12.75 diopters finding statistical significance (p = 0.002). The mean axial length was significantly greater in patients with glaucoma: 30.21 vs 28.93 mm (p < 0.001).</div></div><div><h3>Conclusions</h3><div>Our results firstly suggest that increased axial length and greater refractive error are directly related to the prevalence of glaucoma in patients with high myopia. The non-association between a higher prevalence of glaucoma and older age in these patients is of special interest. These findings underscore the importance of increasing awareness of the increased prevalence of glaucoma in people with high myopia.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 9","pages":"Pages 514-520"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144736041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When perfection becomes a burden: The stress of cataract surgeons 当完美成为一种负担：白内障手术的压力。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.06.002

V.M. Asensio-Sánchez

引用次数: 0

Surgical success in rhegmatogenous retinal detachment: New considerations in 2025 孔源性视网膜脱离的手术成功：2025年的新考虑

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.06.010

L. López Guajardo , P. Carnota Méndez , F. González del Valle

引用次数: 0

Pigmentary dispersion syndrome and pigmentary glaucoma: Diagnostic relevance of the classical triad in a Mediterranean population. 色素性色散综合征和色素性青光眼：地中海人群经典三联征的诊断相关性。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-08-23 DOI: 10.1016/j.oftale.2025.08.007

J Benitez-Del-Castillo, M Villalba-Conde, V Amaya-López, M D Pinazo-Duran

{"title":"Pigmentary dispersion syndrome and pigmentary glaucoma: Diagnostic relevance of the classical triad in a Mediterranean population.","authors":"J Benitez-Del-Castillo, M Villalba-Conde, V Amaya-López, M D Pinazo-Duran","doi":"10.1016/j.oftale.2025.08.007","DOIUrl":"https://doi.org/10.1016/j.oftale.2025.08.007","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>To assess prevalence of classic clinical signs of Pigment Dispersion Syndrome (PDS) in PDS and Pigmentary Glaucoma (PG) in caucasian patients from Southern Spain.</p><p><strong>Materials and methods: </strong>Cross-sectional observational case-series study evaluating the prevalence of characteristic clinical signs of PDS: Krukenberg spindle (KS), Trabecular meshwork pigmentation (TMP) and Iris transillumination defects (ITD). Differences between PDS and PG patients are evaluated and the probability of association with PG of clinical signs with statistically significant differences is also calculated (Odds Ratio OR in logistic regression analysis).</p><p><strong>Results: </strong>144 PDS/PG patients. Prevalence of KS, TMP and ITD is 91%, 88.9% and 24.3%. 48 right eyes (66.7%) were PDS and 24 right eyes (33.3%) were considered PG patients. Prevalence of KS is 95.8% in PDS and 91.7% in PG (p = 0.47). Prevalence of TMP is 87.5% in PDS and 95.8% in PG (p = 0.26). Prevalence of ITD is 16.7% in PDS and 41.7% in PG (p = 0.02). OR of those presenting PG is 3.57 for ITD (95% CI 1.17 to 10.85) (p = 0.02).</p><p><strong>Conclusions: </strong>There are no major differences in the prevalence of KS and TMP in our population of patients with PDS/PG compared to published data in the Caucasian population (91% vs 95% for KS and 88.9% vs 86% for TMP) but there are differences in the prevalence of ITD (24.3% vs 86%).</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144982330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0