Archivos de la Sociedad Espanola de Oftalmologia最新文献

Unveiling the Enigma: Gigantic primary de novo poorly-differentiated ductal adenocarcinoma of the lacrimal gland with aggressive features. A case report and literature review.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-28 DOI: 10.1016/j.oftale.2025.03.018

S Malik, C Ahluwalia, A Aziz Khan

{"title":"Unveiling the Enigma: Gigantic primary de novo poorly-differentiated ductal adenocarcinoma of the lacrimal gland with aggressive features. A case report and literature review.","authors":"S Malik, C Ahluwalia, A Aziz Khan","doi":"10.1016/j.oftale.2025.03.018","DOIUrl":"10.1016/j.oftale.2025.03.018","url":null,"abstract":"Primary ductal adenocarcinoma (PDA) of the lacrimal gland is a rare and aggressive malignancy originating from ductal epithelial cells. Its rarity and diverse clinical presentations pose significant diagnostic challenges, emphasizing the need for accurate diagnosis and appropriate management strategies. The study presents an intriguing case of a 50-year-old man with a large de novo primary ductal adenocarcinoma of the lacrimal gland, initially misdiagnosed as a meningeal solitary fibrous tumor due to its atypical clinical presentation of \"down and out\" proptosis. The case underscores the importance of histopathology to achieve a correct diagnosis and guide management decisions. Despite aggressive treatment approaches, the prognosis of primary ductal adenocarcinoma patients remains grim due to its aggressive behavior and tendency for recurrence and metastasis. The present case study emphasizes that a differential of primary ductal adenocarcinoma should be considered despite the presence of anomalous clinical and radiological presentation.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-28 DOI: 10.1016/j.oftale.2025.03.019

L Gallardo Martin, B Burgos-Blasco, B Vidal-Villegas, J I Fernandez-Vigo, J Garcia-Feijoo, J M Martinez-de-la-Casa

{"title":"Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma.","authors":"L Gallardo Martin, B Burgos-Blasco, B Vidal-Villegas, J I Fernandez-Vigo, J Garcia-Feijoo, J M Martinez-de-la-Casa","doi":"10.1016/j.oftale.2025.03.019","DOIUrl":"https://doi.org/10.1016/j.oftale.2025.03.019","url":null,"abstract":"Purpose: To analyze cytokines in tear and aqueous humour as biomarkers for evaluation of severity of glaucoma.Design: Cross-sectional study.Subjects and methods: Tear and aqueous humour samples were collected from 15 exfoliative glaucoma (XFG) patients, 43 primary open-angle glaucoma (POAG) patients and 33 controls (eligible for cataract surgery). A total of 27 inflammatory cytokines were analyzed in the tear and aqueous humor samples by the Bio-Plex Pro Human Cytokine 27-Plex Immunoassay kit: interleukin (IL)-1b, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL9, IL-10, IL-12, IL-13, IL-15, IL-17, eotaxin, fibroblast growth factor (FGF) basic, granulocyte colony-stimulating factor, granulocyte-monocyte colony-stimulating factor, interferon-γ, interferon gamma-induced protein, monocyte chemo-attractant protein-1, macrophage inflammatory protein (MIP)-1a, MIP-1b, platelet-derived growth factor, regulated on activation normal T cell expressed and secreted, tumor necrosis factor-α and vascular endothelial growth factor.Results: In the tear samples a statistically significant difference in Il-2, IL-4, IL-9, IL-12, IL-15 and FGF-basic between study groups was observed. In aqueous humor, a statistically significant difference of the following cytokines was observed: IL-5, IL-6, IL-12 and MCP-1. Il-4 and IL-15 differences correlate with the number of topical drugs, while IL-9 and IL-15 are associated with the visual field mean defect.Conclusion: Inflammation is strongly associated with glaucoma and some cytokines may be related to glaucoma severity.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbiological profile of bacterial and fungal corneal ulcers at a national institute of ophthalmology in Perú. 秘鲁国家眼科研究所细菌性和真菌性角膜溃疡的微生物概况。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-27 DOI: 10.1016/j.oftale.2025.03.017

R Navarro, E Ballesteros-Zamalloa, R Hualpa-Vicente, P Minami, M A Rodriguez-Cuba

{"title":"Microbiological profile of bacterial and fungal corneal ulcers at a national institute of ophthalmology in Perú.","authors":"R Navarro, E Ballesteros-Zamalloa, R Hualpa-Vicente, P Minami, M A Rodriguez-Cuba","doi":"10.1016/j.oftale.2025.03.017","DOIUrl":"10.1016/j.oftale.2025.03.017","url":null,"abstract":"Objective: To describe the microbiological profile of bacterial and fungal corneal ulcers, as well as the antibiotic susceptibility profile of the most frequent pathogenic species.Methods: A retrospective descriptive study was conducted using the recorded data of corneal ulcer scrapings from the ocular microbiology laboratory of the National Institute of Ophthalmology. Laboratory data from 2015 to 2022 were collected and included for all corneal ulcer scrapings.Results: After excluding repeated, non-cultured, and duplicate results, a total of 3,470 corneal samples were analyzed. Positive samples accounted for 88.1% of all scraps. Of these, 2,816 (81.2%), 904 (26.2%), and 662 (19.1%) showed bacterial, fungal, and mixed growth, respectively. Coagulase-negative Staphylococci (2,257; 69.8%) were the most frequent bacteria, with Staphylococcus epidermidis (1,677; 51.9%) being the most isolated organism, followed by Pseudomonas aeruginosa (275; 8.5%) and Staphylococcus aureus (274; 8.5%). Fusarium spp. was the most common fungus. Less than 60% of S. epidermidis isolates showed susceptibility to Oxacillin, Cefazolin, Moxifloxacin, and Gentamicin, while more than 90% of isolates were susceptible to Gatifloxacin. P. aeruginosa showed less than 80% susceptibility only to Imipenem.Conclusion: Gram-positive bacteria were the most isolated, with S. epidermidis being the most frequent pathogen, followed by P. aeruginosa. S. epidermidis exhibited alarmingly low susceptibility to commonly used antibiotics.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endothelial changes in patients with and without diabetes after manual small-incision cataract surgery.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-22 DOI: 10.1016/j.oftale.2025.03.016

L A Oseguera Chávez, L E Salas Medina, C Palacio Pastrana, W Cedillo Suárez

{"title":"Endothelial changes in patients with and without diabetes after manual small-incision cataract surgery.","authors":"L A Oseguera Chávez, L E Salas Medina, C Palacio Pastrana, W Cedillo Suárez","doi":"10.1016/j.oftale.2025.03.016","DOIUrl":"10.1016/j.oftale.2025.03.016","url":null,"abstract":"Background and objective: In Mexico there is a high prevalence of diabetes, which is one of the most frequent etiologies of cataract. The impact of diabetes on postoperative corneal decompensation associated with MSICS has not been studied in our country. The objective of the study was to determine the difference in corneal endothelial changes between diabetic and non-diabetic patients by preoperative specular microscopy and at one month and 3 months after MSICS.Patients and methods: Prospective, longitudinal, paired, non-randomized study with two groups; Group 1: diabetic patients and Group 2: non-diabetic patients. All patients had a complete ophthalmologic evaluation and preoperative and postoperative specular microscopy at one month and 3 months.Results: 119 eyes were included. The percentage of CD loss at 1 month was 11.1% in diabetic patients and 6.3% in non-diabetic patients. At 3 months the percentage of loss was 9.9% in diabetic patients and 5.4% in non-diabetic patients. The CV was higher in patients with diabetes and was significant at 1 month; however, at 3 months the values were comparable. The percentage of HEX decreased significantly in the first month in patients with diabetes.Conclusions: There was a significant difference with greater CD loss, greater CV and less HEX in patients with diabetes vs. without diabetes at 1 month after the M-SICS procedure, however, it was not statistically significant at 3 months. This suggests greater endothelial stress, longer recovery time and remodeling of the corneal endothelium in patients with diabetes.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Central toxic keratopathy after refractive surgery: Diagnosis, treatment and challenges in the routine clinical practice.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-22 DOI: 10.1016/j.oftale.2025.03.015

A Robles García, Y Fernández Barrientos, J L Ramos Navarro, J Díaz Bernal, J Mora Castilla, J Ortega Usobiaga

引用次数: 0

Maculopathy due to hypotony: A diagnostic challenge.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-20 DOI: 10.1016/j.oftale.2025.03.013

M M Valentín-Pastrana Aguilar, B Sandoval Cortés, S Durán Poveda, L Guerrero Altares, B García Sandoval

引用次数: 0

Surprising complete regression of a choroidal neovascular membrane with faricimab.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-20 DOI: 10.1016/j.oftale.2025.03.012

F Garcia Ibor, N Ruiz Del Rio, A M Duch Samper

引用次数: 0

Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-20 DOI: 10.1016/j.oftale.2025.03.014

A B González Escobar, I E Molina Guilabert, R M García Herrera, I M Baquero Aranda, R Luque Aranda, J M Galván Cano

引用次数: 0

XEN 63 in a case of refractory glaucoma secondary to microphthalmia and aphakia.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.010

S Labay-Tejado, J Laguna, M J Navarro-Angulo, L Muñoz, M Jodar, E Milla

引用次数: 0

Retinal vasculitis associated with intravitreal bevacizumab injection: A case report.

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.011

S Murillo-Lopez, S Medina-Medina

引用次数: 0