Archivos de la Sociedad Espanola de Oftalmologia最新文献

Value of vitamin A supplements in increasing macular thickness in a patient with vitamin A deficiency and nyctalopy. 维生素A补充剂增加维生素A缺乏症患者黄斑厚度的价值。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-04 DOI: 10.1016/j.oftale.2025.10.001

L Dominguez García, P Spang-Valencia, C Leis-Cofiño, J Villagrá Lecuona, P Monreal-Lodeiros, I Rosa Pérez

引用次数: 0

Simulating Glaucoma Progression in the Retinal Ganglion Cell Layer with Generative Adversarial Networks. 用生成对抗网络模拟视网膜神经节细胞层青光眼的进展。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-04 DOI: 10.1016/j.oftale.2025.10.002

Peraza Alejandro, Gómez-Perera Sandra, Arnay Rafael, Sigut Saavedra José, Díaz-Alemán Tinguaro

{"title":"Simulating Glaucoma Progression in the Retinal Ganglion Cell Layer with Generative Adversarial Networks.","authors":"Peraza Alejandro, Gómez-Perera Sandra, Arnay Rafael, Sigut Saavedra José, Díaz-Alemán Tinguaro","doi":"10.1016/j.oftale.2025.10.002","DOIUrl":"https://doi.org/10.1016/j.oftale.2025.10.002","url":null,"abstract":"<p><strong>Objective: </strong>The main objective of this study is to develop a tool capable of synthesizing images of the ganglion cell layer (GCL) that simulate glaucoma progression using generative antagonistic networks (GANs).</p><p><strong>Material and methods: </strong>The dataset includes 406 GCL images of 76 eyes with glaucoma and progression, recorded by a spectral domain optical coherence tomograph (OCT). The Pix2Pix model, a conditional antagonistic generative network, was used to transform the current GCL images into images representing glaucoma progression. A total of 70% of the samples were used for training and 30% for model testing. The structural similarity coefficient was used to analyze the similarity between the real and generated images, and finally, an expert's opinion was used to assess the originality of the generated images.</p><p><strong>Results: </strong>The synthesized images successfully replicate glaucoma lesion patterns, with good generalizability and reproducibility. The results show a mean structural similarity between 0.76 and 0.78 in the different tests. The test with the expert obtained an accuracy of 57% in distinguishing between real and generated images.</p><p><strong>Conclusions: </strong>The system developed can generate synthetic images of the GCL with a high similarity to the real ones, demonstrating the effectiveness of the model in synthesizing images that represent the evolution of glaucoma.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial intelligence and telemedicine in oculoplastics: Recent advances, clinical applications, and emerging challenges 人工智能和远程医疗在眼科整形：最新进展，临床应用和新出现的挑战。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.018

F. Calleja Casado , A. Caro Ortega , E. Gracia Rovira , A. Duch Samper

引用次数: 0

Molecular connection between the ocular surface and the inflammasome: New diagnostic and therapeutic perspectives 眼表和炎性体之间的分子连接：新的诊断和治疗观点。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.09.001

S. Mora-Sáez , I. Andrés-Blasco , J. Benítez-del-Castillo-Sánchez , V. Zanón-Moreno , C. Peris-Martínez , M.D. Pinazo-Durán

引用次数: 0

The conceptualization of ‘Key Evidence Leaders’ from ‘Opinion Leaders’: A review also applicable in ophthalmology 从“意见领袖”到“关键证据领袖”的概念：也适用于眼科的综述。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.016

J. Fernández , F. Ribeiro , H.B. Dick , T. Kohnen , C. Rocha-de-Lossada , M. Rodríguez-Vallejo

{"title":"The conceptualization of ‘Key Evidence Leaders’ from ‘Opinion Leaders’: A review also applicable in ophthalmology","authors":"J. Fernández , F. Ribeiro , H.B. Dick , T. Kohnen , C. Rocha-de-Lossada , M. Rodríguez-Vallejo","doi":"10.1016/j.oftale.2025.07.016","DOIUrl":"10.1016/j.oftale.2025.07.016","url":null,"abstract":"<div><div>The collaboration of ophthalmologists with the industry, in their role as opinion leaders (OLs) who interpret, modify, and disseminate information to professional networks, is susceptible to bias. This review explores the critical role of OLs in the healthcare industry and their evolution into Key Evidence Leaders (KELs), emphasizing the importance of differentiating KELs from traditional OLs to promote evidence-based practices and maintain research integrity in healthcare. OLs often rely on their reputation and experience, which can make them susceptible to industry biases, particularly when financial incentives are involved. The concept of KELs marks a significant evolution from traditional OLs. Unlike OLs, KELs base their influence on expertise in clinical evidence and research, rather than personal experience or industry affiliations. KELs possess strong analytical skills, engage in interdisciplinary collaboration, and emphasize transparency and unbiased dissemination of information. The emergence of KELs represents a significant shift towards evidence-based leadership in healthcare. Differentiating KELs from traditional OLs is crucial for ensuring that the messages received by healthcare professionals are less biased. By supporting KELs who prioritize patient-centered evidence, the industry can enhance trust in the application of medical devices and drugs.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 10","pages":"Pages 618-624"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144736045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reconstruction of the upper eyelid after dog bite using a composite graft at pediatric age 小儿犬咬伤后复合移植物重建上眼睑。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.015

C.A. Gómez Lanz , B. Palmero Sánchez , M.V. Carmona Pérez , E. Nevado Sánchez

引用次数: 0

Orbital giant primary osteoma: Case report and literature review 眼眶巨大原发性骨瘤1例报告及文献复习。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.017

M. Dorronsoro, C. Pagano Boza

引用次数: 0

Automated measurement of ocular movements abnormalities in primary congenital glaucoma using DIVE device: A pilot study of fixation, smooth pursuit and saccadic movements 使用DIVE设备自动测量原发性先天性青光眼的眼球运动异常：固定、平滑追踪和跳眼运动的初步研究。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.06.009

L. Morales-Fernandez, C. Heredia-Pastor, P. Talavero, I. Collado, J. Garcia-Feijoo, R. Gomez-de-Liaño

{"title":"Automated measurement of ocular movements abnormalities in primary congenital glaucoma using DIVE device: A pilot study of fixation, smooth pursuit and saccadic movements","authors":"L. Morales-Fernandez, C. Heredia-Pastor, P. Talavero, I. Collado, J. Garcia-Feijoo, R. Gomez-de-Liaño","doi":"10.1016/j.oftale.2025.06.009","DOIUrl":"10.1016/j.oftale.2025.06.009","url":null,"abstract":"<div><h3>Purpose</h3><div>Primary congenital glaucoma (PCG) is a significant cause of childhood vision loss. While visual acuity can be measured, it does not always reflect visual functioning in daily life, particularly as oculomotor skills are often compromised in ocular disorders. This pilot study assesses oculomotor behavior in children with PCG compared to healthy peers using the Device for an Integral Visual Examination (DIVE).</div></div><div><h3>Methods</h3><div>Twelve children with PCG (n = 24 eyes) and 24 healthy children (n = 48 eyes), aged 6 months to 4 years, were recruited. DIVE was used for automated oculomotor assessments, measuring fixation (gaze stability, fixation stability, and duration of fixation), saccadic movements (reaction time, peak velocity), and smooth pursuit (latency, gain).</div></div><div><h3>Results</h3><div>PCG children showed significantly poorer gaze stability in both short (0.68 log degree<sup>2</sup>, 0.29–0.94 frente a 0.15 log degree<sup>2</sup>, −0.17–0.59; p < 0.05) and long tasks (1.08 log degree<sup>2</sup>, 0.79–1.84 frente a 0.57 log degree<sup>2</sup>, 0.30–0.85; p < 0.05), and poorer fixation stability in short (−0.20 log degree<sup>2</sup>, −0.27 to −0.17 frente a −0.48 log degree<sup>2</sup>, −0.55 to −0.30; p < 0.05) and long tasks (−0.11 log degree<sup>2</sup>, −0.20 to −0.04 frente a −0.41 log degree<sup>2</sup>, −0.57 to −0.26; p < 0.05). Fixation durations were shorter, and saccadic reaction times were longer in the PCG group, while pursuit latency showed no significant difference (<em>p = 0.8118</em>).</div></div><div><h3>Conclusions</h3><div>Children with PCG have significantly impaired oculomotor behavior, including greater instability in gaze and fixation, shorter fixation durations, and longer saccadic reaction times compared to healthy peers.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 10","pages":"Pages 610-617"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of anterior segment OCT in peripheral ulcerative keratitis 前段OCT在周围性溃疡性角膜炎中的作用。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.002

C. Parés-Alfonso, D. Oliver-Gutiérrez, E. Ros-Sanchez

引用次数: 0

Ophthalmologic management in KID syndrome: Long-term clinical experience KID综合征的眼科治疗：长期临床经验。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.013

R. Estévez-Domínguez , C. Rocha-de-Lossada , M. Rodríguez-Calvo-de-Mora , J. Etxebarria-Ecenarro , J. García-Montesinos-Gutiérrez

引用次数: 0