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Archivos de la Sociedad Espanola de Oftalmologia最新文献

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Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation. 视网膜病变伴面肩肱肌营养不良。玻璃体内植入地塞米松联合激光光凝治疗1例。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-20 DOI: 10.1016/j.oftale.2025.03.014
A B González Escobar, I E Molina Guilabert, R M García Herrera, I M Baquero Aranda, R Luque Aranda, J M Galván Cano
{"title":"Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation.","authors":"A B González Escobar, I E Molina Guilabert, R M García Herrera, I M Baquero Aranda, R Luque Aranda, J M Galván Cano","doi":"10.1016/j.oftale.2025.03.014","DOIUrl":"10.1016/j.oftale.2025.03.014","url":null,"abstract":"<p><p>Facioscapulohumeral muscular dystrophy (FSHD) is a slowly progressive muscular dystrophy that affects especially the muscles of the face, shoulder girdle and upper arms. It may present extramuscular manifestations such as hearing loss and retinopathy. Up to 75% of patients may show alterations in the retinal vasculature such as vascular tortuosity, microaneurysms, telangiectasias, retinal ischemia and exudation, and in less than 1% of cases it may present as Coats-like syndrome. We present a 40-year-old male with FSHD who, in an ophthalmologic examination, showed exudative retinopathy in his left eye (LE) with peripheral retinal ischemia treated with laser therapy, and macular edema (ME) treated with intravitreal dexamethasone injection (IDI). We would like to emphasize the importance of performing an ophthalmological examination on all patients with FSHD to rule out associated retinal pathology, and thus prevent loss of visual acuity (VA) with early treatment.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
XEN 63 in a case of refractory glaucoma secondary to microphthalmia and aphakia. xen63继发于小眼和无晶状体的难治性青光眼1例。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.010
S Labay-Tejado, J Laguna, M J Navarro-Angulo, L Muñoz, M Jodar, E Milla
{"title":"XEN 63 in a case of refractory glaucoma secondary to microphthalmia and aphakia.","authors":"S Labay-Tejado, J Laguna, M J Navarro-Angulo, L Muñoz, M Jodar, E Milla","doi":"10.1016/j.oftale.2025.03.010","DOIUrl":"10.1016/j.oftale.2025.03.010","url":null,"abstract":"<p><p>Microphthalmia (MO) predisposes to glaucoma and congenital cataracts (CC). Cataract removal in MO is characterized by several complications such as aphakic glaucoma (AG). We report the case of a 33-year-old male with MO, aphakia, and refractory glaucoma who underwent inferonasal ab-interno XEN 63 implantation, after posterior vitrectomy. Whole Exome Sequencing (WES) analysis was performed identifying the likely pathogenic variant c.197G>A (p.Cys66Tyr) in heterozygosity in the PAX6 gene related to Peters anomaly (PA) and the variant of unclear significance c.353T>C (p.Leu118Pro) in heterozygosity in the CRYBB3 gene, potentially related to CC. Until the 12-month follow-up, the patient maintained intraocular pressure (IOP) between 16 and 18 mmHg without medication or complications. XEN 63, when combined with posterior vitrectomy may be an option in select cases, owing to its versatility. However, further investigation is required. Genetic analysis provides a pre-symptomatic diagnosis and may lead to a more personalised medicine.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinal vasculitis associated with intravitreal bevacizumab injection: A case report. 视网膜血管炎与玻璃体内注射贝伐单抗：1例报告。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.011
S Murillo-Lopez, S Medina-Medina
{"title":"Retinal vasculitis associated with intravitreal bevacizumab injection: A case report.","authors":"S Murillo-Lopez, S Medina-Medina","doi":"10.1016/j.oftale.2025.03.011","DOIUrl":"10.1016/j.oftale.2025.03.011","url":null,"abstract":"<p><p>Anti-vascular endothelial growth factor drugs are the treatment of choice for macular edema due to venous occlusions. While rare, they have been associated with some uncommon adverse effects. We present a case of retinal vasculitis associated with bevacizumab in a72-year-old woman who presented to our clinic with sudden visual acuity loss in her left eye due to macular edema following central vein occlusion. She was treated with bevacizumab, with a minor inflammatory response that resolved with topical steroids. After 6 weeks, the macular edema recurred and a 2<sup>nd</sup> dose of bevacizumab was indicated, with a severe inflammatory reaction that resolved with periocular steroids and topical NSAIDs. Systemic vasculitis and infectious diseases were ruled out and treatment was switched to aflibercept with no adverse effects being reported.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Female ophthalmologists' perception of occupational hazards during pregnancy. 女眼科医生妊娠期职业危害的认知。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.006
V M Asensio-Sánchez, L De Juan Hernández
{"title":"Female ophthalmologists' perception of occupational hazards during pregnancy.","authors":"V M Asensio-Sánchez, L De Juan Hernández","doi":"10.1016/j.oftale.2025.03.006","DOIUrl":"10.1016/j.oftale.2025.03.006","url":null,"abstract":"","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined retro-recession on a single muscle for the correction of incomitant vertical strabismus. 单侧肌肉联合退退矫正非共同性垂直斜视。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.002
J A Reche-Sainz, L de-Pablo-Gómez-de-Liaño, A Iribarra-Fermandois, A López-Alcaide, M Ferro-Osuna
{"title":"Combined retro-recession on a single muscle for the correction of incomitant vertical strabismus.","authors":"J A Reche-Sainz, L de-Pablo-Gómez-de-Liaño, A Iribarra-Fermandois, A López-Alcaide, M Ferro-Osuna","doi":"10.1016/j.oftale.2025.03.002","DOIUrl":"10.1016/j.oftale.2025.03.002","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of the combined resection-recession technique in correcting incomitant vertical strabismus.</p><p><strong>Methods: </strong>A retrospective study was conducted on four adult patients with incomitant vertical strabismus, treated using the resection-recession technique on the inferior rectus muscle, with the resection amount being at approximately 50% of the recession. Surgeries were performed under topical anaesthesia and sedation, using adjustable sutures, allowing for intraoperative adjustments. Deviation in prism dioptres (PD) was measured in primary position and in the incomitant position, both before and after surgery. Success was defined as a reduction in incomitance greater than 50% and the preservation of orthotropia in primary position.</p><p><strong>Results: </strong>Three patients were female and one was male, with a mean age of 58 years (range 38-80 years). The mean preoperative deviation in downgaze was 13 PD (range 10-16 PD), which reduced to 0.5 PD (range 0-1 PD) following surgery. The mean preoperative incomitance was 12 PD (range 10-14 PD), decreasing to 0.5 PD (range 0-1 PD) postoperatively (p < 0.05), representing a 95.8% reduction in incomitance. All patients achieved orthotropia in primary position. In one case, an intraoperative adjustment was necessary to correct a limitation in downgaze. No significant intraoperative complications were recorded.</p><p><strong>Conclusions: </strong>The combined resection-recession technique appears to be effective and safe for the correction of vertical incomitant strabismus, achieving significant reduction in incomitance while maintaining alignment in primary position. The option for intraoperative adjustments may enhance surgical outcomes.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experience of the application of botulinum toxin type A as a treatment of facial hyperkinetic disorders in a Mexican ophthalmological center. 在墨西哥眼科中心应用A型肉毒杆菌毒素治疗面部多动障碍的经验。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.009
P D Lara-Barrera, J L Tovilla-Canales, O Olvera-Morales, E G Castillo-Pérez, Á Nava-Castañeda
{"title":"Experience of the application of botulinum toxin type A as a treatment of facial hyperkinetic disorders in a Mexican ophthalmological center.","authors":"P D Lara-Barrera, J L Tovilla-Canales, O Olvera-Morales, E G Castillo-Pérez, Á Nava-Castañeda","doi":"10.1016/j.oftale.2025.03.009","DOIUrl":"10.1016/j.oftale.2025.03.009","url":null,"abstract":"<p><strong>Background and objective: </strong>Blepharospasm is characterized by involuntary, sustained spasms of the orbicularis oculi, corrugator, and procerus muscles. Hemifacial spasm (HFS) is characterized by the involuntary tonic-clonic contraction of the muscles of a hemiface. The main role of botulinum toxin type A (BoNT-A) in the treatment of blepharospasm and HFS is recognized by guidelines around the world. In this study, we evaluated the applicability of botulinum toxin type A in patients with periocular hyperkinetic disorders at the Instituto de Oftalmología Fundación Conde de Valenciana, so that we can share the Mexican experience with the international evidence.</p><p><strong>Materials and methods: </strong>The clinical records of patients diagnosed with facial hyperkinetic disorders treated with botulinum toxin type A (BoNT-A) that were treated from January 2015 to September 2021 were analyzed.</p><p><strong>Results: </strong>A total of 140 records of patients diagnosed with facial hyperkinetic disorder and treated with BoNT-A were analyzed. Facial hyperkinetic disorders that occurred included 5 (3.6%) patients with orbicularis oculi myokymia, 72 (51.4%) with blepharospasm, 62 (44.3%) with hemifacial spasm, and 1 (0.7%) with Meige syndrome. One hundred and twenty patients (85.7%) reported remission of initial symptoms after BoNT-A therapy during the period covered by this study.</p><p><strong>Conclusions: </strong>Botulinum toxin type A is effective and safe as a treatment for facial hyperkinetic disorders in the Mexican population.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Krogh's principle, glaucoma, and the 'extremophile' eye of whales. 克拉夫原理，青光眼，以及鲸鱼的“极端生物”眼睛。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.007
J González-Martín-Moro, A Bravo-Nuevo, M A García-Cabezas
{"title":"Krogh's principle, glaucoma, and the 'extremophile' eye of whales.","authors":"J González-Martín-Moro, A Bravo-Nuevo, M A García-Cabezas","doi":"10.1016/j.oftale.2025.03.007","DOIUrl":"10.1016/j.oftale.2025.03.007","url":null,"abstract":"","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serious incidents involving ocular medical devices reported to the AEMPS. 向AEMPS报告的涉及眼科医疗器械的严重事故。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.008
L C Ramón-Carreira, E M Sobas, J C Pastor
{"title":"Serious incidents involving ocular medical devices reported to the AEMPS.","authors":"L C Ramón-Carreira, E M Sobas, J C Pastor","doi":"10.1016/j.oftale.2025.03.008","DOIUrl":"10.1016/j.oftale.2025.03.008","url":null,"abstract":"<p><p>The implementation of the Medical Device Regulation and Royal Decree 192/2023 not only requires manufacturers to enhance safety measures in the production of medical devices but is also complemented by additional regulations impacting hospitals, clinics, and healthcare personnel. Among these is the requirement to identify and report serious incidents to the Spanish Agency of Medicines and Medical Devices (AEMPS). To establish a baseline and evaluate the dissemination efforts of these concepts at the level of scientific societies and other organizations, serious incidents involving ophthalmic medical devices reported to AEMPS since 2018 and subject to health alerts have been identified. Although the percentage remains minimal, it is notable that issues with software or equipment such as surgical microscopes and Optical Coherence Tomography (OCT) are now being reported.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinopathy associated with MELAS syndrome. A case report. 视网膜病变与MELAS综合征相关。一份病例报告。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.001
A B González Escobar, E Barco Moreno, M A López-Egea Bueno, J M Galván Cano, R Luque Aranda, A González Gómez
{"title":"Retinopathy associated with MELAS syndrome. A case report.","authors":"A B González Escobar, E Barco Moreno, M A López-Egea Bueno, J M Galván Cano, R Luque Aranda, A González Gómez","doi":"10.1016/j.oftale.2025.03.001","DOIUrl":"10.1016/j.oftale.2025.03.001","url":null,"abstract":"<p><p>MELAS syndrome (mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes) is an inherited disease frequently caused by a mutation in the mitochondrial DNA variant m.3243A>G in the MT-TL1 gene. The most frequent ophthalmologic finding present in 86-87% of patients with this mutation is mitochondrial retinopathy, where the clinical picture may vary from a macular and peripapillary salt-and-pepper granular pattern to chorioretinal atrophy. We present the case of a 47-year-old woman with type 1 diabetes mellitus, epilepsy, leukoencephalopathy, and deafness who was suspected of having mitochondrial disease after fundus examination. We would like to emphasize the importance of suspecting a mitochondrial disease in progressive multisystem disorders associated with neuro-ophthalmological manifestations, since early diagnosis allows for better monitoring of systemic manifestations, reducing morbidity and mortality.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal imaging in peripapillary congenital hypertrophy of retinal pigment epithelium. 先天性视网膜色素上皮乳头周围肥大的多模态成像。
Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-03-07 DOI: 10.1016/j.oftale.2025.03.005
F López-Herrero, J L Sánchez-Vicente, M Portillo-Martínez, J V Guijarro-Ambel, R Barrera-Moyano, J Suárez-Pérez
{"title":"Multimodal imaging in peripapillary congenital hypertrophy of retinal pigment epithelium.","authors":"F López-Herrero, J L Sánchez-Vicente, M Portillo-Martínez, J V Guijarro-Ambel, R Barrera-Moyano, J Suárez-Pérez","doi":"10.1016/j.oftale.2025.03.005","DOIUrl":"10.1016/j.oftale.2025.03.005","url":null,"abstract":"<p><p>Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is a benign congenital hamartoma of the RPE of generally indolent course. It is usually located outside the posterior pole, with peripapillary presentation being a very rare entity (less than 1% of CHRPE cases). It is a pigmented lesion that can evolve into a heterogeneous pigmented lesion with gaps in its interior and a halo of depigmentation. We present the case of a 52-year-old patient with a peripapillary CHRPE in the left eye followed in our service for more than 12 years through a multimodal imaging study. The patient maintained a visual acuity of 1.0, showing a small increase in the size of the atrophic areas within the lesion. No complications were observed. The right eye did not present any alteration.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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