Archivos de la Sociedad Espanola de Oftalmologia最新文献_第3页

Bilateral congenital simple hamartoma of the retinal pigment epithelium. 双侧先天性单纯性视网膜色素上皮错构瘤。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-27 DOI: 10.1016/j.oftale.2025.09.009

S Mejía-Freire, G De La Mata

引用次数: 0

Safety and efficacy profile of the fluocinolone acetonide implant in non-infectious uveitic macular edema: 5-year follow-up. 氟西诺酮植入治疗非感染性葡萄膜性黄斑水肿的安全性和有效性：5年随访

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-20 DOI: 10.1016/j.oftale.2025.09.006

N Ruiz Del Rio, F Garcia Ibor, E Gracia Rovira, J M Vilaplana Mora, L Sanz Gallen, A M Duch Samper

{"title":"Safety and efficacy profile of the fluocinolone acetonide implant in non-infectious uveitic macular edema: 5-year follow-up.","authors":"N Ruiz Del Rio, F Garcia Ibor, E Gracia Rovira, J M Vilaplana Mora, L Sanz Gallen, A M Duch Samper","doi":"10.1016/j.oftale.2025.09.006","DOIUrl":"10.1016/j.oftale.2025.09.006","url":null,"abstract":"Objective: To evaluate the safety and efficacy profile of the fluocinolone acetonide implant (FAI) in patients with non-infectious posterior segment uveitis over a 60-month follow-up period.Methods: We retrospective conducted a study with a mean follow-up of 47 months (minimum, 18; maximum, 60). The study included 11 eyes (9 patients), with a male-to-female ratio of 8:1. The etiology of uveitis was heterogeneous. Efficacy parameters included visual acuity (VA) and Central macular thickness (CMT), and the ones who needed adjuvant therapy or re-injection. Safety parameters focused on the development of cataracts and intraocular hypertension.Results: Real-world outcomes were assessed. Both VA recovery and CMT reduction were achieved between 3 to 6 months after FAI implantation and remained stable at the follow-up. All patients but one were pseudophakic prior to implantation. The phakic patient developed early cataract formation, requiring surgery 9 months post-implantation. All cases had previously received intravitreal dexamethasone. Five eyes (45.4%) required topical hypotensive therapy, and none glaucoma surgery. No patient required periodic adjuvant therapy or additional FAI injections, even among those with the longest follow-up periods. Two cases (18.1%) exhibited mild inflammatory activity in the macular area at months 33 and 35 post-implantation. These episodes were successfully resolved with sub-Tenon triamcinolone injections, maintaining clinical stability thereafter.Conclusions: The fluocinolone acetonide implant (FAI), in our series of cases, turned out to be an effective and safe therapy for non-infectious uveitic macular edema, providing sustained and long-lasting effects, in some cases up to 60 months post-implantation. Sub-Tenon triamcinolone proves to be a valuable adjunctive therapy.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

National study on the management of central serous chorioretinopathy. 中枢性浆液性脉络膜视网膜病变治疗的全国研究。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-20 DOI: 10.1016/j.oftale.2025.09.005

J Lorenzo-Castro, A D Alarcón-García, A Valverde-Megías, J Montero-Hernández, S Copete, P Fernandez-Avellaneda, M Á Zapata, O Ruiz-Moreno, L Arias-Barquet, J I Fernández-Vigo

{"title":"National study on the management of central serous chorioretinopathy.","authors":"J Lorenzo-Castro, A D Alarcón-García, A Valverde-Megías, J Montero-Hernández, S Copete, P Fernandez-Avellaneda, M Á Zapata, O Ruiz-Moreno, L Arias-Barquet, J I Fernández-Vigo","doi":"10.1016/j.oftale.2025.09.005","DOIUrl":"10.1016/j.oftale.2025.09.005","url":null,"abstract":"Background and objectives: To assess the perception and management of central serous chorioretinopathy (CSCR) in Spain through a survey aimed at retinal specialists.Material and methods: The working group designed an original online survey, including 42 questions categorized into 4 sections: clinical perception, diagnosis, clinical management, and prognosis.Results: A total of 114 ophthalmologists completed the survey. The mean age was 46 years (range, 26-72), 54.5% were men, and the mean post-residency experience was 17.5 years. CSCR was perceived as a growing condition by 80% of participants. While 75% believed acute CSCR tends to resolve spontaneously, 63% estimated chronicity in <25% of cases; however, if chronicity occurs, 77% considered spontaneous resolution unlikely without treatment. Besides OCT, OCT angiography was the most used diagnostic imaging modalitu (72%), followed by fundus autofluorescence (65%). Systemic work-up was never considered by 30%, while 62% would only consider it in the presence of bilateral or multifocal cases, with cortisol being the most frequently investigated parameter. Observation is preferred in acute CSCR, while photodynamic therapy is favored in chronic forms. Focal laser and anti-VEGF agents are preferred for extrafoveal leaks and neovascular membranes, respectively. While 80% expect anatomical improvement with treatment, there is consensus on its limited functional benefits.Conclusions: This survey highlights that CSCR is perceived as an increasingly prevalent disease with high recurrence and potential for chronicity. It also reveals preferences and variability in its management among specialists.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relevance of 'popcorn' discovery in retinopathy of premature. “爆米花”发现与早产儿视网膜病变的相关性。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-20 DOI: 10.1016/j.oftale.2025.09.007

E Gracia-Rovira, A Díaz Barrón, A M Duch Samper

引用次数: 0

Ocular surface and tear film in university students who use inhalant substances, mainly vapers. 使用吸入性物质（主要是电子烟）的大学生的眼表和泪膜。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-05 DOI: 10.1016/j.oftale.2025.09.003

A B López Álvarez, D A Ulloa Delgado, D C Palencia Flórez, M C Morón Barreto

{"title":"Ocular surface and tear film in university students who use inhalant substances, mainly vapers.","authors":"A B López Álvarez, D A Ulloa Delgado, D C Palencia Flórez, M C Morón Barreto","doi":"10.1016/j.oftale.2025.09.003","DOIUrl":"10.1016/j.oftale.2025.09.003","url":null,"abstract":"Objective: To determine the state of ocular surface and tear film in college students who are users of inhalants, mainly vapers.Methods: We conducted a descriptive, observational, and cross-sectional study with 62 participants whose sociodemographic characteristics, ocular surface status, tear film and variables related to vaping were evaluated. Individuals with a higher (5-7 times per week of consumption) and lower frequency of vaping (1-4 times per week of consumption) were evaluated. Symptom documentation was standardized using the OSDI questionnaire and biomicroscopy to evaluate ocular adnexa and anterior segment structures, blinking frequency and eye protection index (EPI) were also determined.Results: A total of 76% of participants were men with a median age of 20.37 years, and an age range between 18 and 28 years. Participants with a higher frequency of vaping exhibited blepharitis (60%) (P-value > .05), meibomian gland obstruction (65.63%) (P-value > .05), tarsal conjunctival hyperemia (52.94%) (P-value < .05), tarsal conjunctival hyperemia (52.94%) (P-value < .05), generalized bulbar hyperemia (72.73%) (P-value > .05), papillary reaction (60%) (P-value > .05), conjunctival staining (75%) (P-value > .05), limbal redness (61.54%) (P-value > .05). A normal Schirmer I (median 31 mm/5 min), short tear breakup time (median 3.5 s in BUT) and a lower number of blinks per minute (median 10.75) were found, yet the EPI was lower (median 0.58).Conclusions: Vaping could be associated with ocular health alterations, such as blepharitis, meibomian gland obstruction, conjunctival hyperemia, conjunctival staining and altered tear quality. Follow-up studies are recommended to establish causal relationships.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of factors associated with post-vitrectomy cataract formation in phakic patients undergoing vitrectomy for rhegmatogenous retinal detachment. 玻璃体切除术后孔源性视网膜脱离白内障形成的相关因素分析。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-05 DOI: 10.1016/j.oftale.2025.09.004

A Gibelalde, S Pinar-Sueiro, I Martínez-Soroa

{"title":"Analysis of factors associated with post-vitrectomy cataract formation in phakic patients undergoing vitrectomy for rhegmatogenous retinal detachment.","authors":"A Gibelalde, S Pinar-Sueiro, I Martínez-Soroa","doi":"10.1016/j.oftale.2025.09.004","DOIUrl":"10.1016/j.oftale.2025.09.004","url":null,"abstract":"Introductions and objectives: This study assesses risk factors for developing cataracts after vitrectomy with tamponade for rhegmatogenous retinal detachment (RRD) in phakic patients and explores the potencial causal relationship between RRD surgery and the development of cataracts.Materials and methods: This was a retrospective study analysing the medical records of patients undergoing RRD surgery between 2012 and 2020 (9 years) at Donostia University Hospital (HUD). We collected data on the date of phacoemulsification surgery after vitrectomy surgery for RRD, as well as the type of vitrectomy and patient characteristics.Results: Patients who underwent cataract surgery were on average older (mean age of 60.79 years old ± 9.49) than those who did not undergo this type of surgery during follow-up (52.97 years old ± 13.59), the difference being statistically significant (0P < .0001). Classifying patients by age at the date of the vitrectomy (≤50 years or >50 years of age), we found between-group differences in phacoemulsification rates after vitrectomy in the follow-up period, cataract surgery being performed in a third of the younger group and three-quarters of the older group (P < .0001).Conclusions: Patients with phakic RRD under 50 years old have a lower risk of cataract development after vitrectomy with tamponade than those over 50 years old. The use of long-acting tamponade gases such as C3F8 and silicone oil in phakic patients seems to increase the likelihood of needing early cataract surgery after RRD surgery with PPV.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of 2 swept-source optical biometers: IOLMaster 700 vs. Revo FC 130. 两种扫描源光学生物计的比较：IOLMaster 700与Revo FC 130。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-05 DOI: 10.1016/j.oftale.2025.09.002

A Ortiz, E García, J Ortega, J de Vera, E Vázquez, M Carrillo, V Romero, K Merizalde

{"title":"Comparison of 2 swept-source optical biometers: IOLMaster 700 vs. Revo FC 130.","authors":"A Ortiz, E García, J Ortega, J de Vera, E Vázquez, M Carrillo, V Romero, K Merizalde","doi":"10.1016/j.oftale.2025.09.002","DOIUrl":"10.1016/j.oftale.2025.09.002","url":null,"abstract":"Objective: To evaluate the measurement accuracy of 2 swept-source optical biometers, the IOLMaster 700 and the Revo FC 130, in patients diagnosed with cataracts.Methods: We conducted a prospective, observational and comparative study in patients older than 40 years with cataracts. A single operator performed optical biometry using both devices during the same session. Cataract grading was conducted using the Lens Opacities Classification System III.Results: Biometric measurements were obtained from the 504 eyes of 279 patients, with a mean age of 70.93 ± 8.41 years. Statistically significant differences were found between the IOLMaster 700 and Revo FC 130 in the following parameters: mean keratometry (43.53 ± 1.56 vs 44.27 ± 1.68 diopters), total average keratometry and mean keratometry (43.56 ± 1.55 D vs 44.27 ± 1.67 diopters), white-to-white distance (11.98 ± 0.52 vs 12.66 ± 0.73 mm), and lens thickness (4.53 ± 0.40 vs 4.60 ± 0.40 mm). No significant differences were found in axial length (23.31 ± 0.96 vs 23.25 ± 1.01 mm) or anterior chamber depth (3.02 ± 0.38 vs 3.02 ± 0.37 mm), which were not clinically relevant. No statistically significant differences were found between the IOLMaster 700 measurements of total mean keratometry (43.53 ± 1.56 diopters) and mean keratometry (43.56 ± 1.56 diopters).Conclusions: Although most measurements do not reveal any clinically relevant differences, the 2 devices should not be used interchangeably, mainly due to variations in keratometry readings.","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral parainfectious papillitis superimposed on papillary pseudoedema by optic nerve drusen 双侧感染性副乳头炎叠加视神经麻痹性乳头状假水肿。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.07.004

Javier Garulo Nicolás , Laura Manfreda Domínguez , Patricia Bayo Calduch , Sergio Obiol Ferrando , Andrea Català Nadal , Antonio Miguel Duch Samper

引用次数: 0

Stargardt disease due to ABCA4 mutation in a young adult: Case report and current alternatives for optical and medical treatments 年轻成人因ABCA4突变引起的Stargardt病：病例报告和目前光学和医学治疗的替代方案

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.07.005

D.V. Rey-Rodriguez , M.I. Gómez-Buitrago , M.J. Mateus Parra , L.A. Pazmiño La Rotta , L.F. Aguilar-Serrano

引用次数: 0

Biotechnological novel drug delivery systems for age-related macular degeneration 生物技术新药物递送系统治疗老年性黄斑变性。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-09-01 DOI: 10.1016/j.oftale.2025.07.010

S. Amatha , R. Das , M.K. Gautam , S. Mondal

{"title":"Biotechnological novel drug delivery systems for age-related macular degeneration","authors":"S. Amatha , R. Das , M.K. Gautam , S. Mondal","doi":"10.1016/j.oftale.2025.07.010","DOIUrl":"10.1016/j.oftale.2025.07.010","url":null,"abstract":"<div><div>Recent years have witnessed remarkable advancements in biotechnological ocular drug delivery systems, introducing novel strategies such as gene therapy, cell-based systems, and targeted carriers. This article focuses specifically on age-related macular degeneration (AMD), the most prevalent ocular condition. While gene therapy holds promise for AMD treatment, it also presents significant challenges, leading to the exploration of cell-based therapy as a complementary or alternative approach. To address these hurdles and ensure successful market translation, new companies often form collaborative expert teams encompassing all relevant fields, including regulatory affairs. As medical science continues to evolve, a comprehensive understanding of gene therapy, cell-based delivery, biocompatibility, safety considerations, regulatory aspects, and ongoing clinical trials is essential to fully grasp the safety and effectiveness of these novel ocular therapies. Consequently, this paper primarily explores these key areas. The successful evolution of biotechnological ocular delivery signals a positive shift towards personalized medicine, which is expected to significantly improve the quality of life for AMD patients in the near future.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 9","pages":"Pages 537-548"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0