Archivos de la Sociedad Espanola de Oftalmologia最新文献_第3页

Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma 细胞因子分析评价原发性开角型青光眼和剥脱性青光眼的严重程度。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.019

L. Gallardo Martin , B. Burgos-Blasco , B. Vidal-Villegas , J.I. Fernandez-Vigo , J. Garcia-Feijoo , J.M. Martinez-de-la-Casa

{"title":"Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma","authors":"L. Gallardo Martin , B. Burgos-Blasco , B. Vidal-Villegas , J.I. Fernandez-Vigo , J. Garcia-Feijoo , J.M. Martinez-de-la-Casa","doi":"10.1016/j.oftale.2025.03.019","DOIUrl":"10.1016/j.oftale.2025.03.019","url":null,"abstract":"<div><h3>Purpose</h3><div>To analyze cytokines in tear and aqueous humour as biomarkers for evaluation of severity of glaucoma.</div></div><div><h3>Design</h3><div>Cross-sectional study.</div></div><div><h3>Subjects and methods</h3><div>Tear and aqueous humour samples were collected from 15 exfoliative glaucoma (XFG) patients, 43 primary open-angle glaucoma (POAG) patients and 33 controls (eligible for cataract surgery).</div><div>A total of 27 inflammatory cytokines were analyzed in the tear and aqueous humor samples by the Bio-Plex Pro Human Cytokine 27-Plex Immunoassay kit: interleukin (IL)-1b, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL9, IL-10, IL-12, IL-13, IL-15, IL-17, eotaxin, fibroblast growth factor (FGF) basic, granulocyte colony-stimulating factor, granulocyte-monocyte colony-stimulating factor, interferon-γ, interferon gamma-induced protein, monocyte chemo-attractant protein-1, macrophage inflammatory protein (MIP)-1a, MIP-1b, platelet-derived growth factor, regulated on activation normal T cell expressed and secreted, tumor necrosis factor-α and vascular endothelial growth factor.</div></div><div><h3>Results</h3><div>In the tear samples a statistically significant difference in Il-2, IL-4, IL-9, IL-12, IL-15 and FGF-basic between study groups was observed. In aqueous humor, a statistically significant difference of the following cytokines was observed: IL-5, IL-6, IL-12 and MCP-1. Il-4 and IL-15 differences correlate with the number of topical drugs, while IL-9 and IL-15 are associated with the visual field mean defect.</div></div><div><h3>Conclusion</h3><div>Inflammation is strongly associated with glaucoma and some cytokines may be related to glaucoma severity.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 254-263"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation 视网膜病变伴面肩肱肌营养不良。玻璃体内植入地塞米松联合激光光凝治疗1例。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.014

A.B. González Escobar, I.E. Molina Guilabert, R.M. García Herrera, I.M. Baquero Aranda, R. Luque Aranda, J.M. Galván Cano

{"title":"Retinopathy associated with facioscapulohumeral muscular dystrophy. A case report treated with intravitreal dexamethasone implant and laser photocoagulation","authors":"A.B. González Escobar, I.E. Molina Guilabert, R.M. García Herrera, I.M. Baquero Aranda, R. Luque Aranda, J.M. Galván Cano","doi":"10.1016/j.oftale.2025.03.014","DOIUrl":"10.1016/j.oftale.2025.03.014","url":null,"abstract":"<div><div>Facioscapulohumeral muscular dystrophy (FSHD) is a slowly progressive muscular dystrophy that affects especially the muscles of the face, shoulder girdle and upper arms. It may present extramuscular manifestations such as hearing loss and retinopathy. Up to 75% of patients may show alterations in the retinal vasculature such as vascular tortuosity, microaneurysms, telangiectasias, retinal ischemia and exudation, and in less than 1% of cases it may present as Coats-like syndrome. We present a 40-year-old male with FSHD who, in an ophthalmologic examination, showed exudative retinopathy in his left eye (LE) with peripheral retinal ischemia treated with laser therapy, and macular edema (ME) treated with intravitreal dexamethasone injection (IDI).</div><div>We would like to emphasize the importance of performing an ophthalmological examination on all patients with FSHD to rule out associated retinal pathology, and thus prevent loss of visual acuity (VA) with early treatment.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 283-288"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of primary rhegmatogenous retinal detachment. Necessity and importance of scleral buckling surgery 原发性孔源性视网膜脱离的治疗。巩膜屈曲手术的必要性和重要性。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.04.002

L. López Guajardo , F. Armadá Maresca , F. González del Valle

引用次数: 0

Central toxic keratopathy after refractive surgery: Diagnosis, treatment and challenges in the routine clinical practice 屈光手术后中枢性中毒性角膜病变：诊断、治疗及常规临床实践中的挑战。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.03.015

A. Robles García , Y. Fernández Barrientos , J.L. Ramos Navarro , J. Díaz Bernal , J. Mora Castilla , J. Ortega Usobiaga

引用次数: 0

Study of a single eye bank. Characteristics and progression of corneal transplantation from 2016 through 2022 in Galicia (Spain) 单一眼库的研究。加利西亚（西班牙）2016 - 2022年角膜移植的特点和进展

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-05-01 DOI: 10.1016/j.oftale.2025.04.005

L. Zurutuza-Veillet , M.A. Saavedra-García , M. Álvarez-Portela , J. Suanzes-Hernández

{"title":"Study of a single eye bank. Characteristics and progression of corneal transplantation from 2016 through 2022 in Galicia (Spain)","authors":"L. Zurutuza-Veillet , M.A. Saavedra-García , M. Álvarez-Portela , J. Suanzes-Hernández","doi":"10.1016/j.oftale.2025.04.005","DOIUrl":"10.1016/j.oftale.2025.04.005","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the characteristics of donated and transplanted corneas, trends in surgical techniques, and indications for corneal transplantation, and the impact of COVID-19 on a Spanish tissue bank from 2016 through 2022.</div></div><div><h3>Methods</h3><div>We conducted a retrospective analysis of corneal donation records from C<em>omplejo Hospitalario Universitario de A Coruña</em> Cryobiology Unit and Tissue Bank from January 1st, 2016 through June 30th, 2022.</div></div><div><h3>Results</h3><div>Corneal donations and transplants remained stable over 6.5 years, except for declines in 2020–2021. A total of 44.3% of all donated corneas were not transplanted, mainly due to tissue viability issues (41.4%). Donors averaged 60.2 ± 13 years, with a mean corneal endothelial cell count of 2701.3 ± 324.6 cells/mm² and a mean corneal clear zone diameter of 7.7 ± 0.7 mm. The preferred preservation method for keratoplasty was hypothermia (85,9%). Indications included endothelial dysfunction (53.8%), repeated keratoplasty (18.8%), corneal ectasia (15.4%), stromal opacity (7.6%), and tectonic causes (4.9%). Penetrating keratoplasty (PK) was more common (56.3%) than lamellar techniques (43.7%), but endothelial keratoplasty (EK) increased by 27.8% since 2019. EK, predominantly Descemet Membrane Endothelial Keratoplasty (DMEK, 94.1%), was used in 96.7% of endothelial dysfunction cases, although 28.6% were treated with PK. Deep anterior lamellar keratoplasty was primarily used for corneal ectasia (46.8%).</div></div><div><h3>Conclusions</h3><div>The Galicia Tissue Bank exceeds the European Eye Bank Association quality standards. Penetrating techniques remain predominant, but the trend is towards favor lamellar procedures, particularly DMEK. Endothelial dysfunction is the leading and growing indication for corneal transplantation.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 5","pages":"Pages 264-273"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral and simultaneous retinal artery occlusion in a woman with systemic lupus erythematosus. 女性系统性红斑狼疮患者双侧及同时视网膜动脉闭塞。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-04-26 DOI: 10.1016/j.oftale.2025.04.012

V M Asensio-Sánchez

引用次数: 0

Peripapillary intrachoroidal cavitation. 乳头周围脉络膜内空化。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-04-26 DOI: 10.1016/j.oftale.2025.04.011

J C Escribano Villafruela, A Fuentes Zamora, L Gómez Fernández, J R Ruiz Batrés, J L Urcelay Segura

引用次数: 0

Survey on perception and knowledge of over-diagnosis and treatment in glaucoma among Spanish ophthalmologists. 西班牙眼科医生对青光眼过度诊断和治疗的认知和知识调查。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-04-26 DOI: 10.1016/j.oftale.2025.04.013

J González-Martín-Moro, N Ventura-Abreu, J Zarallo-Gallardo, F J Muñoz-Negrete

{"title":"Survey on perception and knowledge of over-diagnosis and treatment in glaucoma among Spanish ophthalmologists.","authors":"J González-Martín-Moro, N Ventura-Abreu, J Zarallo-Gallardo, F J Muñoz-Negrete","doi":"10.1016/j.oftale.2025.04.013","DOIUrl":"https://doi.org/10.1016/j.oftale.2025.04.013","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the perception and knowledge that Spanish ophthalmologists have of overdiagnosis (OD) and overtreatment (OT) in the field of glaucoma.</p><p><strong>Methods: </strong>An anonymous, 26-item online survey was submitted to members of the Spanish Glaucoma Society and the Spanish Ophthalmology Society.</p><p><strong>Results: </strong>Approximately 55% out of the 195 respondents were aware of the current definition of OD/OT. Only 13 (6.7%) believe OD/OT is not a clinically significant problem. There were no significant differences in terms of demographics, type of practice and treatment preferences between ophthalmologists who considered OD/OT important and those who considered OD/OT unimportant, except for a higher proportion of PhDs among the \"not clinically relevant\" group. No differences were found either across groups considering clinical findings/real-world scenarios. \"Peace of mind\" was considered a principal driver of OD/OT by both groups. Moderate OHT was considered the most common clinical scenario for OD/OT, which was estimated to affect 20% of medically treated patients and only 5% of those undergoing surgical procedures.</p><p><strong>Conclusions: </strong>Spanish ophthalmologists reported being aware of the importance of OD and OT. However, only half were aware of the current definition of OD and OT. Most participants believe a White Paper should be produced to reduce the prevalence of OD/OT. The low participation rate and the non-response bias may limit the generalization of the results.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary orbital melanoma in a patient with nevus of Ota. 太田痣患者原发性眼眶黑色素瘤。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-04-15 DOI: 10.1016/j.oftale.2025.04.009

M V Segura Fernández-Nogueras, M Tirado Pascual, H Piñas Hormeño, C Alba Linero

引用次数: 0

Very late-onset neuromyelitis optica, a report of two cases. 非常晚发性视神经脊髓炎2例报告。

Archivos de la Sociedad Espanola de Oftalmologia Pub Date : 2025-04-15 DOI: 10.1016/j.oftale.2025.04.010

A Matheu Fabra, J E Martínez Rodríguez, B Beltrán Mármol, M Saint-Gerons Trecu

引用次数: 0