M Larrañaga Cores, M Asencio Durán, J Peralta Calvo, M Feito Rodríguez, G Amorena Santesteban, A Del Hierro Zarzuelo, A Boto-de-Los-Bueis
{"title":"Intravitreal Fluocinolone Acetonide Implant (ILUVIEN®) for the treatment of ocular juvenile xanthogranuloma.","authors":"M Larrañaga Cores, M Asencio Durán, J Peralta Calvo, M Feito Rodríguez, G Amorena Santesteban, A Del Hierro Zarzuelo, A Boto-de-Los-Bueis","doi":"10.1016/j.oftale.2025.08.002","DOIUrl":null,"url":null,"abstract":"<p><p>This is the case of a 14-years-old woman referred to our ophthalmology department with suspected iris juvenile xanthogranuloma, with reported bilateral, hematic recurrent uveitis as soon as she discontinued treatment with topical prednisolone acetate eye drops. After numerous treatments at the 3-year follow-up, including oral steroids, repeated injections of subtenon triamcinolone acetonide and intracameral and intravitreal anti-VEGF, treatment with intravitreal fluocinolone acetonide implant (ILUVIEN®) in both eyes was decided. Evolution since then and at the 10-month follow-up has been satisfactory; the patient has not exhibited any new episodes of ocular inflammation or hyphema despite the progressive withdrawal of topical corticosteroids, and vision has remained at 20/20 in both eyes. As far as we know, this is the first case of bilateral ocular juvenile xanthogranuloma successfully treated with an intravitreal fluocinolone implant.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos de la Sociedad Espanola de Oftalmologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.oftale.2025.08.002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
This is the case of a 14-years-old woman referred to our ophthalmology department with suspected iris juvenile xanthogranuloma, with reported bilateral, hematic recurrent uveitis as soon as she discontinued treatment with topical prednisolone acetate eye drops. After numerous treatments at the 3-year follow-up, including oral steroids, repeated injections of subtenon triamcinolone acetonide and intracameral and intravitreal anti-VEGF, treatment with intravitreal fluocinolone acetonide implant (ILUVIEN®) in both eyes was decided. Evolution since then and at the 10-month follow-up has been satisfactory; the patient has not exhibited any new episodes of ocular inflammation or hyphema despite the progressive withdrawal of topical corticosteroids, and vision has remained at 20/20 in both eyes. As far as we know, this is the first case of bilateral ocular juvenile xanthogranuloma successfully treated with an intravitreal fluocinolone implant.
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