Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme最新文献

{"title":"Effects of quercetin ingestion on neuromuscular system following single session of resistance exercise at differing intensities in older adults.","authors":"Taichi Nishikawa, Ryosuke Takeda, Marino Karaki, Kaito Igawa, Kohei Watanabe","doi":"10.1139/apnm-2025-0169","DOIUrl":"https://doi.org/10.1139/apnm-2025-0169","url":null,"abstract":"<p><p>The purpose of this study was to investigate whether quercetin ingestion increases the decline in muscle contractile capacity due to a single resistance exercise session at differing intensities. Thirty-eight older adults took part in this study. They were divided into three intensity groups: low- (LI), moderate- (MI), and high-intensity (HI) groups. Each participant completed two single resistance exercise sessions of resistance exercise at 40 (LI), 60 (MI), or 80 (HI) % of maximal voluntary contraction. Before each session, they ingested either a placebo or quercetin glycoside (500 mg). Motor unit behavior and electrically elicited contraction torque were measured by high-density electromyography and neuromuscular electrical stimulation at pre-ingestion, post-ingestion, and post-exercise. Quercetin ingestion decreased the motor unit recruitment thresholds from pre- to post-ingestion (p<0.001). The decline in electrically elicited contraction torque following exercise was greater with quercetin than placebo ingestion in LI and MI groups (low: p=0.014; moderate: p=0.025), but not in the HI group (p=0.792). The greater the decline of electrically elicited contraction torque following exercise by quercetin ingestion, the greater the decrease in the recruitment threshold of motor units with a higher threshold by quercetin ingestion in LI and MI groups (low: p=0.047, rs=0.566; moderate: p=0.011, rs=0.692), but not in the HI group (p=0.228). These results suggest that quercetin ingestion accelerates the decline in muscle contractile capacity following low- or moderate-intensity resistance exercise, possibly due to the additional recruitment of higher-threshold motor units.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145246128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vestibular-evoked balance responses are blunted in lowlanders and Tibetan highlanders with ascent to 4,300 m.","authors":"Jessica A Dickenson, Mathew I B Debenham, Brian H Dalton, Taylor S Harman, Ajaya J Kunwar, Nilam Thakur, Sunil Dhungel, Nima Sherpa, Abigail W Bigham, Tom D Brutsaert, Trevor A Day, Nicholas D J Strzalkowski","doi":"10.1139/apnm-2025-0191","DOIUrl":"https://doi.org/10.1139/apnm-2025-0191","url":null,"abstract":"<p><p>Hypoxia influences postural control and vestibular function. However, the vestibular control of standing balance at high altitude is poorly understood. Furthermore, Tibetan highlanders are physiologically adapted to high-altitude, but it is unclear if vestibular-driven signals for balance within this population acclimate differently than lowlanders with ascent. This study investigated vestibular-evoked balance responses in unacclimatized lowlanders and Tibetan highlanders at low altitude (1,400m) and after six- or seven-days of incremental ascent to high altitude (4,300m). Twenty-eight participants (15 lowlanders, 8F, 7M; 13 Tibetan highlanders, 7F, 6M) stood on a force plate facing forward with their eyes closed and underwent 90-second stochastic electrical vestibular stimulation trials at a peak-to-peak amplitude of ±2 or ±4 mA. Vestibular-evoked balance responses were quantified using cumulant density and coherence (0-5 Hz and 5-10 Hz) between electrical vestibular stimulation and mediolateral forces. With ±2mA stimulation, the peak-to-peak amplitude of vestibular-evoked balance responses decreased at high compared to low altitude for both groups (P=0.003). With ±4mA stimulation, only lowlanders showed a reduction in peak-to-peak amplitude at high altitude (P=0.03), and their responses were smaller than Tibetan highlanders at high altitude (P=0.046). For frequency-domain outcomes, lowlanders exhibited a smaller 0-5 Hz coherence area at high compared to low altitude with ±2mA stimulation (P=0.002), whereas Tibetan highlanders showed no change. No differences in coherence area were observed in either group with ±4mA stimulation. These findings indicate that while the vestibular control of balance is blunted at high altitude for lowlanders and highlanders, the altitude effect is greater in lowlanders.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderate-intensity exercise-induced changes in lactate do not predict changes in corticospinal excitability.","authors":"Cassidy Klein, Jess Gibson, Hayley N Pettigrew, Derek S Kimmerly, Shaun G Boe","doi":"10.1139/apnm-2025-0146","DOIUrl":"https://doi.org/10.1139/apnm-2025-0146","url":null,"abstract":"<p><p>INTRODUCTION/PURPOSE Aerobic exercise increases corticospinal excitability (CSE), creating an optimal environment for learning to occur. It has been hypothesized that this may be a result of lactate accumulation in the blood during exercise. However, while prior literature has linked moderate-intensity exercise with enhanced CSE, previous lactate-based work has mainly used maximal or fatiguing exercise. To date, the effect of lactate concentration on CSE during steady-state moderate-intensity exercise has not been investigated. METHODS Twenty-four participants (13F, mean age 23.7 ± 2.7) attended two separate study sessions. Session 1: Participants completed a maximal graded exercise test on a cycle ergometer. Session 2: Participants completed a moderate-intensity exercise session (20-min of cycling at 60% peak power output). Measures of CSE obtained from the first dorsal interosseous (FDI) muscle were assessed via transcranial magnetic stimulation before, immediately after, and 10-min following the exercise session. Lactate was obtained via blood sample at these same timepoints. RESULTS Linear regression demonstrated that lactate concentration did not predict an exercise-induced change in CSE immediately following exercise (R2 = 0.02184, F(1, 22) = 0.4913, p = 0.4907) or 10-min post-exercise (R2 = 0.02121 F(1, 22) = 0.4767, p = 0.4971). CONCLUSION These results suggest that lactate is not the primary mechanism behind alterations in CSE driven by moderate-intensity exercise.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vagotomy improves brown adipose tissue morphology and reduces steatosis in obese mice.","authors":"Antonio Machado Felisberto Junior, Andresa Jesica Zamoner, Jean Franciesco Vettorazzi, Janaina de Oliveira Chaves, Vanessa Cristina de Souza Melo, Amanda Gotz Lopes, Joseane Morari, Paulo Roberto Ribeiro, Antonio C Boschero, Rosane A Ribeiro, Maria Lúcia Bonfleur, Sandra Lucinei Balbo","doi":"10.1139/apnm-2025-0190","DOIUrl":"https://doi.org/10.1139/apnm-2025-0190","url":null,"abstract":"<p><p>The abolishment of vagal abdominal afferents and efferents inputs through vagotomy has been shown to prevent obesity. However, it is unknown whether such a strategy, performed after obesity installation, may treat, or ameliorate obesity and its comorbidities. Here, we aimed to verify the effects of subdiaphragmatic vagotomy on obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) in obese mice that continued to be fed an obesogenic diet after the operation. Obesity was induced in male C57Bl/6 mice by ingestion of a high-fat diet (HFD). Afterward, obese (OB) mice were randomly submitted to Sham (OB-Sham group) or subdiaphragmatic vagotomy (OB-Vag group) and continued to be fed a HFD for 8 weeks. Vagotomy led to reductions in body weight (BW), without modifying food intake in OB-Vag mice. While these rodents showed no modifications in subcutaneous fat accumulation, they exhibited higher abdominal adiposity. In contrast, the weight of the interscapular brown adipose tissue (BAT) was lower in OB-Vag mice, with brown adipocytes in its parenchyma showing reduced size and fewer lipid vacuoles, resembling the high-thermogenic adipocyte type. This effect was partially explained by increased gene expressions of Prdm16, Pgc-1α and Dio2, key factors maintaining BAT identity and function. Furthermore, subdiaphragmatic vagotomy enhanced glucose tolerance, insulin sensitivity, improved serum, and hepatic lipids levels and ameliorated MASLD in OB-Vag mice. Vagotomy performed after obesity induction improved BAT function and insulin sensitivity, which may partly contribute to alleviating MASLD in OB mice that continued to consume an obesogenic diet.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of decreased hemoglobin levels with worse muscle mass and strength in community-dwelling older people.","authors":"Zimin Wang, Masashi Taniguchi, Yosuke Yamada, Misaka Kimura, Yoshihiro Fukumoto, Masahide Yagi, Noriaki Ichihashi","doi":"10.1139/apnm-2025-0215","DOIUrl":"https://doi.org/10.1139/apnm-2025-0215","url":null,"abstract":"<p><p>We investigated the associations between red blood cell (RBC) count, hemoglobin (Hb) levels, muscle properties, and muscle strength in community-dwelling older adults, and examined whether RBC count and Hb levels were linked to muscle strength through muscle mass and/or quality, and whether these relationships were influenced by physical activity. The study included 85 community-dwelling older adults (39 males; mean age 75.3 ± 6.7). The participants visited the laboratory in the morning for venous blood sampling to analyze blood biomarkers. Quadriceps femoris muscle thickness (MT, muscle mass index) and echo intensity (EI, muscle quality index) were measured via B-mode ultrasonography, and maximum isometric knee extension strength was assessed using a dynamometer. The average daily step count was recorded for 2 weeks as an index of physical activity. Correlation and mediation analyses were used to investigate the associations between blood biomarkers and muscle properties, strength, and physical activity. The RBC count and Hb levels were positively correlated with MT and muscle strength, and negatively correlated with EI. After adjusting for age and sex, the correlations between RBC count, Hb levels, and MT and muscle strength remained significant, whereas the associations with EI disappeared. In the mediation analyses, the direct effect of RBC count and Hb levels on muscle strength was not significant, whereas the indirect effect of MT was, regardless of whether physical activity was adjusted. In community-dwelling older adults, lower RBC counts and Hb levels appear to be associated with diminished muscle mass, potentially resulting in muscle weakness.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the temporal effects of ovarian failure on single muscle fibre contractility using a chemically-induced ovarian failure model in mice.","authors":"Parastoo Mashouri, Jinan Saboune, Glen Pyle, Geoffrey Alonzo Power","doi":"10.1139/apnm-2025-0130","DOIUrl":"https://doi.org/10.1139/apnm-2025-0130","url":null,"abstract":"<p><p>We investigated the effects of chemically-induced ovarian failure on single fibre contractility of the soleus and extensor digitorum longus (EDL) muscles throughout ovarian failure, thereby mimicking the menopausal transition into late-stage menopause: [(D60;peri-menopause), (D120;onset of menopause), (D134;early-onset menopause), (D176;late-stage menopause)]. We used 4-vinylcyclohexene diepoxide (VCD) to induce ovarian failure in sexually-mature female mice. For the soleus at D120 and D176, mice with VCD-induced ovarian failure produced higher force as compared with controls (p<0.05). On D134, however, VCD had lower force production compared with controls (p<0.05). The cross-sectional area of the soleus fibres from the VCD group was larger at D120 compared with controls (p<0.05), but not at any other time point (p>0.05). The VCD group showed time-dependent changes in specific force production compared to controls, with a 37% decrease at D134 but a 39% increase at D176 in the soleus muscle (p<0.05). No differences in rate of force redevelopment (Ktr) or calcium sensitivity was observed for the soleus (p>0.05). For the EDL there were no differences in force, cross-sectional area, stiffness, Ktr, or calcium sensitivity between groups (p>0.05). Our results indicate that muscle contractility across the peri-menopausal transition into late-stage menopause is both muscle and phase-dependent, emphasizing the complexity of changing hormones throughout the lifespan on muscle contractile function.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiorespiratory response to high-intensity interval exercise across the menstrual cycle and with oral contraceptive use in recreationally active females.","authors":"Alyssa A Olenick, Regis C Pearson, Nathan T Jenkins","doi":"10.1139/apnm-2025-0112","DOIUrl":"https://doi.org/10.1139/apnm-2025-0112","url":null,"abstract":"<p><p>Fluctuations in female sex hormones may influence the cardiorespiratory response to exercise. Cardiorespiratory response to high-intensity interval exercise (HIIE) across the menstrual cycle (MC) or with oral contraceptive (OC) use has limited data. Therefore, the influence of MC phase and OC use on cardiorespiratory response during HIIE was assessed. Twenty-five females (24.4 (3.6) yr) were categorized by a natural MC (NOC, n = 14) or OC use (n = 11). HIIE was four sets of four repetitions with three-minute rest between intervals on a cycle ergometer at a power output halfway between the ventilatory threshold and V̇O2peak. A HIIE bout was performed during the early follicular and mid-luteal phases (days 2-7 and ~21 of the MC) and during inactive (days 2-7) and active pill (third week) phases. Cardiorespiratory responses to HIIE were assessed via indirect calorimetry. No group or cycle phase differences were noted for relative and absolute VO2, ventilatory exchange, heart rate, or rating of perceived exertion (p > 0.05). In NOC during the follicular phase, FEO2 and V̇E/V̇O2 during pre-exercise seated rest was lower compared to the luteal phase (p < 0.05). In NOC during the follicular phase, V̇E/CO2, FEO2, FECO2, V̇E/V̇O2, and V̇E/CO2 during warm-up was lower compared to the luteal phase (p < 0.05). Most cardiorespiratory variables assessed do not appear to be impacted by MC phase or OC use during HIIE.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case-control study of pectoralis major muscle quality in breast cancer survivors after radiation therapy without prior axillary lymph node dissection.","authors":"Anna E Lamport, Jamie S K Takayesu, David B Lipps, Suzi Wolfram","doi":"10.1139/apnm-2025-0058","DOIUrl":"https://doi.org/10.1139/apnm-2025-0058","url":null,"abstract":"<p><p>Radiation therapy for breast cancer is associated with considerable radiation to the pectoralis major, which causes muscle fibrosis and reduces muscle quality. The present study examined pectoralis major muscle quality after radiation therapy in breast cancer survivors using ultrasound echo intensity (EI). Twelve breast cancer survivors treated with radiation therapy to breast and axilla (breast + axilla group) and twelve survivors treated with radiation therapy to the breast only (breast only group) were compared to twelve cancer-free control women. All breast cancer survivors underwent breast-conserving surgery and sentinel node biopsy before radiation therapy. The pectoralis major was imaged with ultrasound on the treated side in breast cancer survivors and a randomly chosen side in controls. EI values were acquired from these images as a measure of muscle quality. Total body fat percentage was obtained from DXA scans. EI of the pectoralis major differed between the groups (p = 0.013), where EI values were higher in the breast + axilla group (p = 0.049) and breast only group (p = 0.013) compared to controls. Mediation-based regression analysis showed that the effect of radiation on EI is significantly mediated by body fat percentage. Higher pectoralis major EI in the breast cancer groups suggests lower muscle quality after radiation therapy, which may contribute to the shoulder functional deficits experienced by many breast cancer survivors. The findings suggest that this poorer muscle quality may result from higher body fat percentage and is exacerbated by radiation exposure.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Long Muscle Length Isometric versus Full Range of Motion Isotonic Training on Regional Quadriceps Femoris Hypertrophy in Resistance-Trained Individuals.","authors":"Dorian Varovic, Kristian Zganjer, Milo Wolf, Patroklos Androulakis-Korakakis, Brad Jon Schoenfeld, Pavle Mikulic","doi":"10.1139/apnm-2025-0238","DOIUrl":"https://doi.org/10.1139/apnm-2025-0238","url":null,"abstract":"<p><p>This study explored the effects of isometric training at long muscle lengths (ISOM) vs. full range of motion (ROM) isotonic training (ISOT) on quadriceps femoris regional hypertrophy. Twenty-three healthy, resistance-trained men and women completed a 6-week, twice-per-week intervention. A within-subject study design was employed with limbs randomized to unilateral ISOM or ISOT knee extension. Muscle thickness was assessed pre- and post-intervention at proximal, middle, and distal sites of the anterior thigh and lateral thigh. Data was analyzed using Bayesian linear mixed-effects models. The between-condition estimate for summed anterior thigh muscle thickness was -0.20 cm (high-density credible intervals [HDI]: -0.54, 0.16), with 87% probability of direction (pd) and 75% of the posterior distribution exceeding the region of practical equivalence (ROPE). At the proximal site of the anterior thigh, between-condition estimates showed the greatest directional shift in favor of ISOM (contrast estimate: -0.11 cm [95% HDI: -0.24, 0.02]), with 82% of the posterior distribution exceeding the ROPE. Minimal to negligible changes in summed and regional lateral thigh muscle thickness were found for both conditions. Overall, ISOM and ISOT elicited similar quadriceps hypertrophy in resistance-trained individuals. Isometric training at long muscle lengths may elicit a superior hypertrophic effect in the proximal anterior thigh; however, uncertainty in the effect estimates precludes definitive conclusion in this regard and further investigation is warranted.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthropometric Profiles, Adiposity, and Physical Fitness in Long-Haul Truck Drivers: Implications for Chronic Disease Risk.","authors":"Keely A Shaw, Gordon A Zello, Alexander M Crizzle","doi":"10.1139/apnm-2025-0188","DOIUrl":"https://doi.org/10.1139/apnm-2025-0188","url":null,"abstract":"<p><p>Long-haul truck drivers (LHTD) face unique occupational challenges, including prolonged sedentary periods, irregular meal patterns, and limited access to physical activity, contributing to high levels of adiposity and elevated risks for chronic diseases. This study examined relationships between anthropometric measures, body composition, physical fitness, and occupational factors among Canadian LHTD and compared field-testing equipment for assessments of body composition. 197 LHTD underwent assessments of body anthropometry (body mass index, skinfold thickness, bioelectrical impedance analysis, segment circumference), grip strength, and completed a survey on physical activity and the work environment. Over a fifth (22%) reported not engaging in any moderate to vigorous activity in the past week. Grip strength was negatively correlated with body fat percentage (p<0.001), waist-to-height ratio (p<0.001), waist circumference (p=0.03), work- (p=0.021) and leisure-time (p=0.01) physical activity, and years worked in the industry (p=0.003). Increased waist circumference positively correlated with hours driven continuously (p=0.007) and years worked in the industry (p=0.004), while waist-to-height ratio was positively correlated with years as a LHTD (p<0.001). All body composition assessment methods exhibited large coefficients of variation, though the measurement error was generally low except for the Taylor Body Analyzer, and agreement between tools tended to decrease with higher levels of body fat. These findings highlight the high rates of adiposity and reduced physical fitness in long-haul truck drivers. Tailored interventions focusing on dietary improvements, physical activity, and strength training should be prioritized to mitigate chronic disease risk in this population.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}