Annals of burns and fire disasters最新文献_第4页

Reepithelialization of partial thickness porcine burns treated with silver sulfadiazine, triple antibiotic or petrolatum. 磺胺嘧啶银、三联抗生素或凡士林治疗部分厚度猪烧伤的再上皮化。

Annals of burns and fire disasters Pub Date : 2024-12-31 eCollection Date: 2024-12-01

S A Sober, S Wong, Y Shoham, S Sandoval, A J Singer

{"title":"Reepithelialization of partial thickness porcine burns treated with silver sulfadiazine, triple antibiotic or petrolatum.","authors":"S A Sober, S Wong, Y Shoham, S Sandoval, A J Singer","doi":"","DOIUrl":"","url":null,"abstract":"Topical antibiotic application and occlusive dressings stand as the current standard of care for partial thickness burn (PTB) treatment. Silver sulfadiazine (SSD) is the most widely used topical antimicrobial agent for acute burn management worldwide. Despite its antimicrobial benefits, there is emerging evidence that SSD might delay wound reepithelialization. We hypothesized that when compared with a topical antibiotic ointment, wound reepithelialization with SSD would be delayed. We created 21 partial thickness burns on the backs of 3 anesthetized female domestic pigs (30kg) using an established vertical progression model. The burns were randomly assigned to topical treatment with SSD, triple antibiotic ointment, or petrolatum ointment applied daily for two weeks, followed by twice weekly for another 2 weeks with intermittent dressing changes. The primary outcome was percentage wound reepithelialization at day 21. Our study had 80% power to detect a 25-percentage difference in wound reepithelialization at day 21. All wounds were completely reepithelialized within 28 days of burn creation. At day 21 the mean (SD) percentages for wound reepithelialization were 73.6 (38.2), 93.2 (16.3), and 65.0 (48.9) in wounds treated with SSD, triple antibiotic, and petrolatum respectively, P=0.049. There was no significant difference among treatment groups in scar depth at day 28. Pseudoeschar formation and erythematous hypersensitivity reactions were common findings on gross analysis with SSD and topical antibiotics respectively. We conclude that SSD delayed reepithelialization of partial thickness porcine burns when compared with triple antibiotic ointment. There were no significant differences in scar depth among the groups.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 4","pages":"330-337"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Burn hypertrophy scarring assessment based on patient and observer scar assessment scale (POSAS). 烧伤肥厚性疤痕评估基于患者和观察者疤痕评估量表（POSAS）。

Annals of burns and fire disasters Pub Date : 2024-12-31 eCollection Date: 2024-12-01

M H Oley, M C Oley, F L F G Langi, E S Sinaga, D F Gunawan, M Faruk

{"title":"Burn hypertrophy scarring assessment based on patient and observer scar assessment scale (POSAS).","authors":"M H Oley, M C Oley, F L F G Langi, E S Sinaga, D F Gunawan, M Faruk","doi":"","DOIUrl":"","url":null,"abstract":"Hypertrophic burn scars can occur due to imbalances in the healing process and affect quality of life. They can be assessed with the Patient and Observer Scar Assessment Scale (POSAS). This is an assessment instrument with both a patient scale and an observer scale. This study aimed to assess the reliability and validity of the POSAS score to measure the quality of scars in evaluating burns that produce scar tissue. It also aimed to determine similarities in the assessment of scar tissue using the POSAS score according to observers and patients. This cross-sectional study had a sample of 30 patients, including 19 women (63%). Assessments were performed before the initial treatment procedure and 1 and 6 months after. The post-incision scar tissue assessment results using the POSAS instrument were expressed as a score: 5-50 (observer), 6-60 (patient), or 11-110 (both total). The highest degree of burns was superficial-mid-dermal (20 patients; 67%). The POSAS assessment by doctors and patients tended to be the same and decreased at both months 1 and 6 after the treatment procedure. The mean total score was 51.3 ± 12.1 before treatment, 44.2 ± 9.5 at month 1, and 30.3 ± 5.9 at month 6. This study shows that in evaluating burns that produce hypertrophic scars, similarities exist in the POSAS score according to observers and patients. Precautions at the beginning of the observation will affect the POSAS score.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 4","pages":"312-316"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The ambient air and arachis hypogaea (peanut) oil dressing in severe burns in children under 15 years of age at the regional hospital center of dédougou]. [环境空气和花生油敷料在15岁以下严重烧伤儿童中的应用]。

Annals of burns and fire disasters Pub Date : 2024-12-31 eCollection Date: 2024-12-01

I W Bahikoro, B Some, M Windsouri, A F Sanon, R Doamba, A S T Sanon, S L C Yameogo, A Yameogo, S F M Ouedraogo, C Bagré, E Ouangré, A Sanou

{"title":"[The ambient air and arachis hypogaea (peanut) oil dressing in severe burns in children under 15 years of age at the regional hospital center of dédougou].","authors":"I W Bahikoro, B Some, M Windsouri, A F Sanon, R Doamba, A S T Sanon, S L C Yameogo, A Yameogo, S F M Ouedraogo, C Bagré, E Ouangré, A Sanou","doi":"","DOIUrl":"","url":null,"abstract":"The dressing is an important element in the management of severe burns. The aim of this study was to present the results of the dressing in room air and peanut oil. This was a descriptive retrospective study conducted from January 1, 2014 to December 31, 2020 in the surgery department of the Dédougou regional hospital center. All patients less than or equal to 15 years of age with a severe burn were included. They all benefited from a dressing protocol in ambient air and with arachis hypogaea (peanut) oil. We collected 81 children with an average age of 4.8 years. All the burns were accidental and they were thermal in 77 cases (95%). They occurred during the harmattan period in 43 cases (53%). The average burned body surface was 23.2%. The burns were deep 2nd degree in 48 cases (59.3%). There were 16 infectious complications (19.7%), including 15 cases (18.5%) of suppuration. Death occurred in two cases. The average epidermization time was 26.2 days and the average length of hospital stay was 12.5 days. Sequelae were noted in 16 cases (20.25%) and 15 cases were adults. The results of the application of the dressing protocol in ambient air and with arachis hypogaea (peanut) oil are encouraging. A larger scale study will provide additional evidence on its efficacy and safety.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 4","pages":"317-322"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological trends for burn wound infections in 2020 in albania. 阿尔巴尼亚2020年烧伤创面感染流行病学趋势。

Annals of burns and fire disasters Pub Date : 2024-12-31 eCollection Date: 2024-12-01

L Deda, M K Belba

{"title":"Epidemiological trends for burn wound infections in 2020 in albania.","authors":"L Deda, M K Belba","doi":"","DOIUrl":"","url":null,"abstract":"The burn patient is at high hazard for nosocomial infections (NI) as a result of the nature of the burn damage itself, the immune-compromising impacts of burns, prolonged clinic stays, and intensive diagnostic and therapeutic strategies. The aim of this study is to describe the actual epidemiology of burn wound colonization and infection in the Intensive Care Unit (ICU) of the Service of Burns and Plastic Surgery at the University Hospital Center in Tirana, Albania. The study is retrospective clinical and analytical. Microbiology data, total body surface area (TBSA), patient days (LOS) and mortality were collected from a hospital database for all patients admitted to the ICU of the Service of Burns at the UHC in Tirana, Albania in 2020. The burn wound infection prevalence rate was greater than in 2010 (17.2 vs. 12 infections per 100 patients), while the burn wound colonization prevalence rate was reduced by half (20.6 vs. 44 colonized patients for 100 patients). The burn wound infection incidence rate was increased (47 vs. 42.6 infections per 1000 hospitalization days) and also the attack rate was increased (0.7 vs. 0.5 infections for 100 patients in 2010). The main pathogens were gram-positive bacteria (60 strains; 71%), followed by Gram-negative bacteria (22 strains; 26%), and fungi (3 strains; 3%). The predominant five bacteria were Staphylococcus aureus (55.0%), Pseudomonas aeruginosa (9%), Acinetobacter baumannii (8%), Staphylococcus coagulase-negative (8%) and Enterococcus faecalis (5%). Methicillin-resistant Staphylococcus aureus (MRSA) accounted for 55.3% (31/56) of Staphylococcal isolates. Implementation of anti-microbial stewardship programs is necessary to optimize the treatment of sepsis.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 4","pages":"270-280"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The clinical application of adipofascial turnover flaps for coverage of severe burn wounds on the digits. 将脂肪筋膜翻转瓣用于覆盖严重烧伤的手指伤口的临床应用。

Annals of burns and fire disasters Pub Date : 2024-12-31 eCollection Date: 2024-12-01

N D T Linh, T V Anh, H T Tuan, V Q Vinh

引用次数: 0

COMPARATIVE STUDY OF STRIPED CATFISH (PANGASIUS HYPOPHTHALMUS) SKIN, NILE TILAPIA (OREOCHROMIS NILOTICUS) SKIN, AND PORCINE SKIN AS A XENOGRAFT MATERIAL FOR BURN WOUND. 带鱼（pangasius hypophthalmus）皮、尼罗罗非鱼（oreochromis niloticus）皮和猪皮作为烧伤异种移植材料的比较研究。

Annals of burns and fire disasters Pub Date : 2024-09-30 eCollection Date: 2024-09-01

A T Purnomo, A N Syarif, A Wardhana, N C Siregar

{"title":"COMPARATIVE STUDY OF STRIPED CATFISH (PANGASIUS HYPOPHTHALMUS) SKIN, NILE TILAPIA (OREOCHROMIS NILOTICUS) SKIN, AND PORCINE SKIN AS A XENOGRAFT MATERIAL FOR BURN WOUND.","authors":"A T Purnomo, A N Syarif, A Wardhana, N C Siregar","doi":"","DOIUrl":"","url":null,"abstract":"Burn injury remains a health problem, specifically in Indonesia. In major burns, xenograft has been proved to be useful as temporary wound coverage. However, some xenografts are not widely available due to cultural, financial and religious backgrounds, or have an unesthetic appearance, such as the scaly appearance of tilapia fish xenograft. Striped catfish (Pangasius hypophthalmus) is a scaleless fish that has abundant type 1 collagen. This study aimed to compare striped catfish skin to commonly used xenograft (Nile tilapia and porcine skin) as xenograft material for burn wound. In this experimental study, nine different skin samples of striped catfish, Nile tilapia and porcine were prepared and histologically examined using hematoxylin-eosin stained samples. Macroscopic and microscopic features of each sample were documented and analysed. The macroscopic skin appearances of striped catfish were hairless and scaleless with black-silver color and moderate thickness. As for microscopic features, the epidermal thickness of striped catfish skin (8.49±1.60 μm) was significantly different to both Nile tilapia (2.18±0.37 μm; p<0.001) and porcine skin (42.22±14.85 μm; p=0.002). The dermal thickness of striped catfish skin (288.46±119.04 μm) was similar to Nile tilapia (210.68±46.62 μm; p=0.783) but differs significantly to porcine skin (1708.44±505.12 μm; p<0.001). The integrity and collagen organization of striped catfish was also similar to tilapia based on semi-quantitative histology scoring system (p>0.05). Striped catfish had potential macroscopic appearance and comparable microscopic features to Nile tilapia; smoother macroscopic appearance, thicker epidermis, and similar dermis thickness. Therefore, we believe it can be potentially used as a xenograft material. Further studies are required to evaluate the effectiveness and feasibility of striped catfish xenograft in burn wound management.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 3","pages":"242-249"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[VENOUS THROMBO-EMBOLISM IN BURNS: INCIDENCE AND RISK FACTORS]. [烧伤中的静脉血栓栓塞：发生率和风险因素]。

Annals of burns and fire disasters Pub Date : 2024-09-30 eCollection Date: 2024-09-01

H Ben Khalifa, A Mokline, H Fraj, S Zarrouk, I Eljemi, B Gasri, M Ben Saad, A A Messadi

{"title":"[VENOUS THROMBO-EMBOLISM IN BURNS: INCIDENCE AND RISK FACTORS].","authors":"H Ben Khalifa, A Mokline, H Fraj, S Zarrouk, I Eljemi, B Gasri, M Ben Saad, A A Messadi","doi":"","DOIUrl":"","url":null,"abstract":"Venous thromboembolic disease (VTE) in burn patients is an under-diagnosed and potentially serious complication. Its incidence varies according to studies performed. This retrospective and descriptive study conducted in an intensive burn care department in Tunisia over a period of 22 months (January 1, 2021 to October 30, 2022) included 24 patients who presented a thromboembolic complication among a total of 785 admissions (incidence of 3%): pulmonary embolism in 15 cases and deep venous thrombosis (DVT) in 9 cases. The mean age of the patients was 43.8 years, with a male:female sex ratio of 2:1. Two thirds of patients (n=17) had a pathological history: hypertension (n=3); diabetes (n=2) and neoplasia (n=2). Three patients were obese. The average TBSA was 29%. Burns involved lower limbs in 19 patients (79%). The mean time to onset of VTE was 27.8 days. Acute dyspnea was present in 1/2 of cases and tachycardia in 1/3 of cases. The association hypoxia-hypocapnia was found in 5 patients. The diagnosis was confirmed by: thoracic angioscan (n=14), pulmonary scintigraphy (n=1), venous Doppler ultrasound of the lower limbs (n=2) and phleboscan of lower limbs (n=7). Factors correlated with thromboembolic risk in our study were: TBSA 20% - 39% (p=0,029; RR=4), with lower limb involvement (p=0,068), catheterization duration ≥7 days (p=0,048; RR=3) and number of catheters >1 (p=0,01; RR=3). The outcome was favorable in 13 patients and fatal in 11 patients.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 3","pages":"233-237"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BACTERIAL NANOCELLULOSE DRESSING COMPARED WITH HYDROCOLLOID DRESSING FOR THE TREATMENT OF PARTIAL-THICKNESS SECOND-DEGREE BURNS: A PROSPECTIVE, RANDOMIZED CONTROL TRIAL. 细菌性纳米纤维素敷料与水胶体敷料治疗局部二度烧伤的比较：前瞻性随机对照试验。

Annals of burns and fire disasters Pub Date : 2024-09-30 eCollection Date: 2024-09-01

M Rehan, T Iqbal, M H Tariq, M S Khan, Q Tul Ain, M U Sarwar, U Waheed

{"title":"BACTERIAL NANOCELLULOSE DRESSING COMPARED WITH HYDROCOLLOID DRESSING FOR THE TREATMENT OF PARTIAL-THICKNESS SECOND-DEGREE BURNS: A PROSPECTIVE, RANDOMIZED CONTROL TRIAL.","authors":"M Rehan, T Iqbal, M H Tariq, M S Khan, Q Tul Ain, M U Sarwar, U Waheed","doi":"","DOIUrl":"","url":null,"abstract":"The management of burn wounds is a major challenge throughout the globe. Superficial and partial-thickness burns generally do not need any surgical intervention, however, severe cases of burn injury require dressings (antimicrobial) and surgery in the worst-case scenario. The present study was conducted to assess the efficacy of bacterial nanocellulose dressing versus hydrocolloid dressing. All patients presenting with partial-thickness second-degree burns from June 2021 to May 2022 were screened for this randomized control trial; 65 burn patients were included in each group of this trial. The control group of patients was treated with hydrocolloid dressing and the experimental group with bacterial nanocellulose dressing sheets. Every third day, the wound was assessed. Other data collected included age, sex, %TBSA burned, signs of infection, time for epithelialization, and length of hospital stay. Statistical analyses were performed to see the significance of differences between the treatment groups by adjusting for size and depth of burn, and the patient's age. There were 130 patients (65 in each group). The median age for the whole group was 17.4 years, and 51.53% (n=67) were males. The average TBSA was 22.4%, with a minimum of 10% and a maximum of 31%. Eleven of the patients had their burns excised, and four were given skin grafts in the control group. In the case of the experimental group, four excisions were performed, and one skin graft. Wound-related pain scores were low (mean of 2.6) for the bacterial nanocellulose group and higher for the hydrocolloid group. Hydrocolloid dressing is more cost effective than bacterial nanocellulose dressing. However, the pain scores were high, and healing time was less in the bacterial nanocellulose group. Moreover, the hydrocolloid group is more prone to infection due to frequent dressing changes.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 3","pages":"226-232"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[ATTEMPTED SUICIDE BY SELF-IMMOLATION IN TUNISIA: 11 YEARS AFTER THE REVOLUTION]. [突尼斯自焚未遂事件：革命 11 年之后]。

Annals of burns and fire disasters Pub Date : 2024-09-30 eCollection Date: 2024-09-01

I Rjeibi, A Mokline, H Fredj, B Gasri, I Jemi, A ALoui, M Ben Saad, A A Messadi

{"title":"[ATTEMPTED SUICIDE BY SELF-IMMOLATION IN TUNISIA: 11 YEARS AFTER THE REVOLUTION].","authors":"I Rjeibi, A Mokline, H Fredj, B Gasri, I Jemi, A ALoui, M Ben Saad, A A Messadi","doi":"","DOIUrl":"","url":null,"abstract":"Self-immolation represents a relatively frequent cause of burn, especially in Tunisia after the revolution, with high costs at the individual and societal level. In this retrospective study, we report epidemiological, clinical and evolutionary characteristics of burns by immolation at the CTB of Tunis over a period of 10 years. The study involved 755 patients over the 10 years. The mean age was 33.38 years with a sex ratio of 4.5:1 (618 M/ 137F). Half of the patients (51%) were single, 2/3 (74.3%) had an unfavourable or medium socioeconomic level, 35.8% were unemployed. The educational level was secondary in 46% of cases and primary in 33.9%. Secondary transfer was noted in 53.6% of cases with agreement in 57.8%. The patients came from all regions of Tunisia with a predominance of those from the Tunis area (37.8%). One third of our patients had a psychiatric history, with the notion of a previous suicide attempt in 5.1% of cases. Alcoholism and/or drug addiction was reported in 17.7% of cases. The act of self-immolation was performed in a public place in 59.2% of cases. TBSA was 41.48%. Burns were deep in 66.2% of cases. Facial involvement was noted in 90% of patients. ABSI was 7.35 and Baux index 78 +/- 50. The average length of stay was 17.64 days. 2/3 of patients (72.1%) required intubation and mechanical ventilation. The mortality rate was 57.2%.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 3","pages":"250-254"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AN OUTBREAK OF EXTENSIVELY DRUG-RESISTANT ACINETOBACTER BAUMANNII IN A BELGIAN TERTIARY BURN WOUND CENTER. 比利时烧伤三级治疗中心爆发广泛耐药鲍曼不动杆菌疫情。

Annals of burns and fire disasters Pub Date : 2024-09-30 eCollection Date: 2024-09-01

D I Costescu Strachinaru, J-L Gallez, A Verroken, J Wagemans, C Lood, D De Vos, J-P Pirnay, R Lavigne, T Rose, M Strachinaru, P Vanbrabant, P Soentjens

{"title":"AN OUTBREAK OF EXTENSIVELY DRUG-RESISTANT ACINETOBACTER BAUMANNII IN A BELGIAN TERTIARY BURN WOUND CENTER.","authors":"D I Costescu Strachinaru, J-L Gallez, A Verroken, J Wagemans, C Lood, D De Vos, J-P Pirnay, R Lavigne, T Rose, M Strachinaru, P Vanbrabant, P Soentjens","doi":"","DOIUrl":"","url":null,"abstract":"The burn intensive care unit (ICU) of the Queen Astrid Military Hospital experienced an outbreak with an extensively drug-resistant Acinetobacter baumannii (XDR-Ab) strain, which began when all burn wound patients from all over Belgium were sent there as part of the national COVID-19 action plan. The purpose of this study is to report on the investigation and strategies that were implemented to contain the outbreak. Between October 2020 and May 2021, five of the 72 patients admitted to the ICU met the acute outbreak case definition (attack rate 7%). Their median age was 46 years and their median total body surface area burned was 39%. All patients developed at least one XDR-Ab infection, with in total three pulmonary, three bloodstream and five burn wound infections. One patient died. All XDR-Ab isolates were only susceptible to colistin. Whole genome sequencing of the isolates from the first two patients revealed an identical A. baumannii ST2 genotype, suggesting an outbreak. XDR-Ab-positive patients were cohorted with dedicated staff. The infection control team intensified its training on hand hygiene, excreta management and bio-cleaning procedures. Concurrently, 30 environmental samples were collected, which proved negative for XDR-Ab. Spatio-temporal associations were found for all XDR-Ab-positive patients, suggesting cross-transmission via staff's hands. We describe an XDR-Ab outbreak in a burn ICU over a seven-month period, in a context of increased workload. This series underlines the importance of a correct staff-to-patient ratio, especially in outbreak situations.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"37 3","pages":"217-225"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0