Annals of burns and fire disasters最新文献

A novel use of amniotic bilayer dressing co-cultured with keratinocytes and stem cell as skin substitute in adult burn patients. 羊膜双层敷料与角质形成细胞和干细胞共培养作为成人烧伤患者皮肤替代物的新应用。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

N M Putri, A Wardhana, C L Sukasah, N Sandora, Rahyussalim, A R Harahap, N C Siregar, H Soedjana, J Prihartono

{"title":"A novel use of amniotic bilayer dressing co-cultured with keratinocytes and stem cell as skin substitute in adult burn patients.","authors":"N M Putri, A Wardhana, C L Sukasah, N Sandora, Rahyussalim, A R Harahap, N C Siregar, H Soedjana, J Prihartono","doi":"","DOIUrl":"","url":null,"abstract":"Survival outcome of burn patients is increasingly higher with early excision and grafting. The problem after excisional debridement is the need for a skin graft or a temporary dressing. By using an amniotic membrane, which is a biological waste, we can limit the use of auto-skin grafts. A preliminary prospective study was conducted on adult patients with no other comorbidities admitted to dr. Cipto Mangunkusumo Hospital Jakarta Burn Unit between 2021-2022. Patients were divided into three groups, treated with early excision and skin grafting, the amnion bilayer dressing or amniotic bilayer dressings co-cultured with keratinocytes and human amniotic epithelial stem cells (hAESC). The patients were then followed up for two weeks and the resulting epithelization in each group was analyzed, including a skin biopsy for confirmation of the epidermal layer thickness. A total of six patients, two in each group, were included in the study. The amniotic bilayer dressings co-cultured with keratinocytes and stem cell group has a rapid rate of epithelization (10% / day) compared to the early excision and skin grafting and amnion bilayer group (7.14% / day). It also has the thickest epidermal layer (95.7μm - range: 67.4-124.02 μm) and the highest histological score (7.00) at two weeks follow-up. This preliminary study concluded that amniotic bilayer dressings co-cultured with keratinocytes and stem cells had an overall better outcome regarding epithelization rate, suggesting that further study is necessary to evaluate amniotic bilayer dressings co-cultured with keratinocytes and stem cell use in burn patients.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"38 1","pages":"46-52"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Upper gastrointestinal bleeding in severely burned patients: incidence, risk factors and outcome. 严重烧伤患者上消化道出血：发生率、危险因素和结局。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

B Tlili, H Fredj, A Mokline, H Galai, S Zarouk, B Gasri, I Jemi, A A Messadi

{"title":"Upper gastrointestinal bleeding in severely burned patients: incidence, risk factors and outcome.","authors":"B Tlili, H Fredj, A Mokline, H Galai, S Zarouk, B Gasri, I Jemi, A A Messadi","doi":"","DOIUrl":"","url":null,"abstract":"Upper gastrointestinal bleeding (UGIB) is a rare complication of the ICU stay. Our objective was to study the epidemiological, clinical manifestations, and evolutionary characteristics of UGIB, and identify its risk factors in severely burned patients. This is a retrospective case-control study of burned patients in the ICU in Tunisia over a period of 6 years, including all adult patients with severe burns who presented at least one episode of gastrointestinal bleeding. The control group consisted of severely burned patients with no gastrointestinal bleeding during their ICU stay. The two groups were matched according to age, gender and extent of burns. The incidence of gastrointestinal bleeding was 2.3% with an average time of onset of 19±17 days. Esophagogastroduodenoscopy was performed in 45 patients showing bulbar ulcer, gastric ulcer, and oesophageal ulcerations in respectively 28, 8 and 3 patients. In the multivariate study, acute kidney injury (OR 13.8, CI [2.9-67], p=0.001), fluid intake <2 ml/kg/%TBSA over the first 24h (OR 10, IC [1.5-68.5], p=0.019), and length of ICU stay >10 days (OR 48.2, IC [4.4-530], p=0.002) were independent risk factors for the occurrence of gastrointestinal bleeding. Mortality in the UGIB group was higher (55.8% vs 25%, p=0.001). Upper gastrointestinal bleeding is a serious complication of a burn patient's ICU stay. Acute renal failure, low fluid intake in the first 24h, and a long duration of ICU stay were independent risk factors for its occurrence.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"38 1","pages":"38-45"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Covering of loss of substance of the dorsal surface of the fingers by abdominal flap: a case report. 腹部皮瓣复盖手指背表面缺损1例。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

A Dehhaze, R Labbaci, N-I Daghouri, O Taybi, I Diher, H Tazi, M Echmili, A Mai, H Barij, O Bouazza, M Mahioui

引用次数: 0

[In vitro activity of ceftazidime- avibactam and ceftolozane- tazobactam against clinical isolates of enterobacteriaceae and pseudomonas æruginosa: results from a trauma center and burn unit in tunisia]. [头孢他啶-阿维巴坦和头孢托ozane-他唑巴坦对临床分离的肠杆菌科和假单胞菌的体外活性：来自突尼斯创伤中心和烧伤病房的结果]。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

Z Megdiche, M Lamloumi, B Maamar, S Dhraief, A A Messadi, L Thabet

{"title":"[In vitro activity of ceftazidime- avibactam and ceftolozane- tazobactam against clinical isolates of enterobacteriaceae and pseudomonas æruginosa: results from a trauma center and burn unit in tunisia].","authors":"Z Megdiche, M Lamloumi, B Maamar, S Dhraief, A A Messadi, L Thabet","doi":"","DOIUrl":"","url":null,"abstract":"Antibiotic resistance is an escalating public health challenge, particularly among Enterobacteriaceae and Pseudomonas aeruginosa. In this study conducted at a burn center in Tunisia, we collected 307 non-redundant strains of Enterobacteriaceae from predominantly hospitalized patients, with a majority in the burn intensive care unit (59%), the primary identified species being Klebsiella pneumoniae (34.8%). We evaluated the efficacy of two antibiotics, ceftazidime-avibactam (CZA) and ceftolozane-tazobactam (CT). The results revealed that the overall resistance to CZA was 11.7%, while to CT it was 25.7%. CZA proved to be the second most sensitive molecule among all tested antibiotics, following fosfomycin. Among strains resistant to third-generation cephalosporins, 73.3% were sensitive to CZA, and 41.5% to CT. Out of seventy-nine CT-resistant strains, eight were ESBL producers, twenty-two were high-level cephalosporinases, thirty-three carried blaNDM, twelve carried blaOXA48, and four carried both blaNDM and blaOXA-48. Indeed, blaNDM were the most prevalent carbapenemases. For Pseudomonas aeruginosa strains (n=161), resistance to CZA was 42.2%, and to CT it was 47.8%. These antibiotics ranked as the second and third most active beta-lactams after aztreonam. Among the 71 strains of CZA and carbapenem-resistant P. aeruginosa, 54.1% produced VIM2. Resistance to enterobacteriaceae against CZA and CT is relatively high in our study. However, CZA remains a salvage therapy for infections caused by carbapenem-resistant organisms, and its use should be considered only after documentation and in the absence of other alternatives among β-lactams. For P. aeruginosa, CZA currently represents the most active β-lactam against CAZ-R strains and the second most active molecule overall, including those producing carbapenemases.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"38 1","pages":"31-37"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Patellar tendon reconstruction using iliotibial tract graft and gastrocnemius pedicled flap, a case report]. 髌胫束植骨加腓肠肌带蒂皮瓣重建髌腱1例。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

P Mateo, P Duhamel, A Duhoux, M Brachet, C-S Bich, E Bey

{"title":"[Patellar tendon reconstruction using iliotibial tract graft and gastrocnemius pedicled flap, a case report].","authors":"P Mateo, P Duhamel, A Duhoux, M Brachet, C-S Bich, E Bey","doi":"","DOIUrl":"","url":null,"abstract":"Large substance loss of the patellar tendon is rare and thus its treatment does not benefit from a consensus. These tendon destructions associated with a vast loss of substance in the surrounding soft tissues make reconstruction a dual challenge because tendon reconstruction and skin coverage must be achieved at the same time. The precocity of the repair and the use of autologous tissue appear to be the determining factors for recovery of the knee function at term. They seem to be independent of the technique used. We report the case of a 36-year-old patient who was diagnosed with purpura fulminans due to strep throat. She was taking non-steroidal anti-inflammatory drugs. The case was complicated by extensive necrosis of the extremities that necessitated a quadruple amputation, notably on the lower extremity: trans femoral on the left and trans tibial on the right. For functional reasons it was imperative to keep the knee straight despite the exposure of the entire extensor system, precarious bone vitality of the patella and necrosis of the patellar tendon. The therapeutic objective was to cover the entire extensor system and reconstruct the patellar tendon by combining the ipsilateral iliotibial tract band and the medial gastrocnemius pedicled flap. At six months follow-up, active flexion and extension of the knee allows walking with suitable prosthetics and without crutches.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"38 1","pages":"77-79"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitriolage in india: analysis by a burn surgeon. 印度的硫酸灼伤：烧伤外科医生的分析。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

T Thussu

{"title":"Vitriolage in india: analysis by a burn surgeon.","authors":"T Thussu","doi":"","DOIUrl":"","url":null,"abstract":"Acid throwing (vitriolage) is a form of violent assault. It is described as an act of throwing acid or corrosives on the body of a person with the intention of injuring or disfiguring them. It is a crime like no other and represents the amalgamation of social evils like patriarchy, gender bias, disdain for the laws of the land, and individual deficiencies like jealousy, anger and sexism. Its incidence has increased over the years and it is soundly entrenched in our society. On the brighter side, surgical care has improved, laws have evolved and, most importantly, society is now aware and is playing an active role against this sacrilege. This study intends to analyze the various aspects of vitriolage in the Indian context, i.e. the extent of the problem, how it affects more than one life, and how the laws have evolved to protect the victims. Secondly, the challenges encountered, from the point of view of a health care worker, specifically a Burns/Reconstructive surgeon, are addressed. It is an attempt to bring on board issues that are medical, administrative or legal and are intricately connected with care and support of victims and survivors of vitriolage. The specific questions discussed in this study are related to the dilemmas faced by the medical community/healthcare institutions while dealing with patients of vitriolage and how the laws have evolved over a period of time.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"38 1","pages":"10-16"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of the combination of platelet-rich plasma and stromal vascular fraction on the level of platelet-derived growth factor-bb in the wound remodeling of full-thickness burn injuries in wistar rats. 富血小板血浆与基质血管组分联合对wistar大鼠全层烧伤创面重塑中血小板源性生长因子-bb水平的影响。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

A Jaya, F Josh, P Prihantono, S R Laidding, S Sulmiati, T H Soekamto, A A Zainuddin

{"title":"Effects of the combination of platelet-rich plasma and stromal vascular fraction on the level of platelet-derived growth factor-bb in the wound remodeling of full-thickness burn injuries in wistar rats.","authors":"A Jaya, F Josh, P Prihantono, S R Laidding, S Sulmiati, T H Soekamto, A A Zainuddin","doi":"","DOIUrl":"","url":null,"abstract":"Experimental studies have shown that the effects of stromal vascular fractions and platelet-rich plasma on deep dermal burn healing were encouraging. By measuring the blood level of platelet-derived growth factor (PDGF)-BB, we evaluated their effect on full-thickness burns in this study. Forty-eight Wistar rats were separated into four main groups: group A rats were administered combined SVF and PRP injections, group B rats were topically administered Vaseline, group C rats were administered placebo injections, and group D rats were without burns. Depending on the day of euthanasia, these groups were further divided into subgroups (8th hour, 4th day, 7th day, 14th day, and 21st day). Using enzyme-linked immunosorbent assay, the serum level of platelet-derived growth factor-BB was determined. Friedman's test or the analysis of variance test was applied, and p-values under 0.05 were regarded as significant. The PRP+SVFs group had the highest mean PDGF-BB levels overall on days 4, 7, 14 and 21 (1.81±1.04 pg/ml, 1.24±0.41 pg/ml, 2.21±0.60 pg/ml, and 3.10±1.02 pg/ml, respectively). The repeated ANOVA test (Mauchly's test of sphericity) resulted in a p-value of 0.556 (>0.05), indicating that the variance of the PDGF-BB data was the same. Additionally, a p-value of 0.001 demonstrated a significant difference in the levels of PDGF-BB between the groups. Overall, the mean PDGF-BB level by day differed significantly between the PRP+SVFs group and the Vaseline group, the negative control group, and the group of healthy rats.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"38 1","pages":"17-24"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Epidemiology and specificities of childhood burns. A 300 case series in a national referral centre]. 儿童烧伤的流行病学和特异性。一个国家转诊中心的300个病例系列研究]。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

A Karray, H Fredj, A Mokline, I Jami, M Ben Saad, B Gasri, O Fattin, L Rebai, F Olfa, A A Messad

{"title":"[Epidemiology and specificities of childhood burns. A 300 case series in a national referral centre].","authors":"A Karray, H Fredj, A Mokline, I Jami, M Ben Saad, B Gasri, O Fattin, L Rebai, F Olfa, A A Messad","doi":"","DOIUrl":"","url":null,"abstract":"Burns are considered a preventable cause of injury in children, associated with significant morbidity and mortality. We conducted a retrospective descriptive study including burned children managed in the burns resuscitation service of Tunis between January 2018 and July 2022. Three hundred burned children were included, representing 14% of admissions. The mean age was 8±5.4 years, with an age below 5 years in 36% of the cases. The majority of patients were male (61%) and the most frequent cause of injury was domestic accident (79%). Immolation by fire was noted only in adolescents. Burns were thermal in 90% of cases, caused by flames (44%) and hot liquids (38%). Electrical burns were noted in 10% of cases. The location of the burns was the home in 80% of cases, mainly the kitchen (44%). The average total burned skin area was 21±16%. The burns involved the trunk and limbs in 50% of cases. Initial cooling was performed in only 25% of cases. Mechanical ventilation was indicated in 22.7% of cases. Amputation of at least one limb was performed in eleven patients with electrical burns (3.7%). The median hospital stay was 14 days [1-172] with a mortality rate of 16%.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"38 1","pages":"3-9"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MBC Report. MBC报告。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

Perniciaro Giuseppe

引用次数: 0

Necrotizing fasciitis: act fast and act together. 坏死性筋膜炎：快速行动，共同行动。

Annals of burns and fire disasters Pub Date : 2025-03-31 eCollection Date: 2025-03-01

D Barreiro, M Mendes, P Machado, I Oliveira, R Horta

{"title":"Necrotizing fasciitis: act fast and act together.","authors":"D Barreiro, M Mendes, P Machado, I Oliveira, R Horta","doi":"","DOIUrl":"","url":null,"abstract":"Necrotizing fasciitis (NF) is a rare and potentially fatal infection of the soft tissues characterized by widespread fascial necrosis and rapid evolution. Diagnosis is often difficult and relies on a high index of suspicion. The approach to this disease requires a timely diagnosis, early antibiotic therapy, aggressive surgical debridement, and reconstructive procedures. All patients treated by the Plastic Surgery department with the diagnosis of NF between 2006-2019 were identified. A retrospective study was conducted with the treatment of patients' demographic and clinical data. Sixty patients with NF who underwent surgical procedures by Plastic Surgery, such as debridement and reconstruction with grafts and flaps, were identified. Up to a third of patients died from complications directly related to the disease. There was 40% complication rate. The average hospital stay was 34.5 days. Plastic surgeons often collaborate in the management of these patients and must recognize the clinical signs early. Early multidisciplinary collaboration is important. The establishment of supportive measures, antibiotics and early surgical debridements are the key to the treatment of this disease.","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"38 1","pages":"80-85"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0