Anales de pediatriaPub Date : 2026-09-01Epub Date: 2026-07-13DOI: 10.1016/j.anpede.2026.504313
Jan Stanisław Bukowski, Tatiana Jamer, Kinga Kowalska-Duplaga, Anna Stelmaszczyk-Emmel, Marcin Banasiuk, Aleksandra Banaszkiewicz
{"title":"The impact of very early and early enteral nutrition on intestinal permeability in children with pancreatitis: A randomized controlled study","authors":"Jan Stanisław Bukowski, Tatiana Jamer, Kinga Kowalska-Duplaga, Anna Stelmaszczyk-Emmel, Marcin Banasiuk, Aleksandra Banaszkiewicz","doi":"10.1016/j.anpede.2026.504313","DOIUrl":"10.1016/j.anpede.2026.504313","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>One of the pathophysiological mechanisms of acute pancreatitis (AP) is the reduced integrity of the intestinal mucosa. Enteral nutrition supports the gut barrier, but its effect on intestinal permeability in pediatric AP has not yet been evaluated. The aim of this study was to assess how very early enteral nutrition (within 24<!--> <!-->hours of admission) and early enteral nutrition (after the first 24<!--> <!-->hours) affect plasma zonulin levels in children with mild-to-moderate AP.</div></div><div><h3>Methods</h3><div>We conducted a prospective randomized study between January 2019 and September 2022 in three university hospitals. It included children aged 1 to 18 years with AP. Patients were randomly assigned to one of two groups: (A) refeeding within 24<!--> <!-->hours of admission (very early nutrition) or (B) refeeding at least 24<!--> <!-->hours after admission (early nutrition). Blood samples and clinical data were collected during the first 3 days of the hospital stay.</div></div><div><h3>Results</h3><div>Zonulin concentrations were measured in 61 children (37 in group A and 24 in group B). The groups did not differ significantly in age, weight, height, body mass index, AP diagnostics, or laboratory results. Zonulin levels were comparable in both groups throughout the first 3 days of hospitalization.</div></div><div><h3>Conclusion</h3><div>In children with mild pancreatitis, very early enteral nutrition does not appear to affect intestinal barrier permeability, as assessed by plasma zonulin levels, compared to early nutrition.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504313"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148439553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-09-01Epub Date: 2026-09-11DOI: 10.1016/j.anpede.2026.504270
Ricardo Suárez Camacho, Nathalie Carreira Sande, Vanesa Crujeiras Martínez, Jose Manuel Martín Morales
{"title":"Submucosal lesions after colonoscopy in a girl with rectal bleeding: Not all are polyps","authors":"Ricardo Suárez Camacho, Nathalie Carreira Sande, Vanesa Crujeiras Martínez, Jose Manuel Martín Morales","doi":"10.1016/j.anpede.2026.504270","DOIUrl":"10.1016/j.anpede.2026.504270","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504270"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148931324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-09-01Epub Date: 2026-09-19DOI: 10.1016/j.anpede.2026.504296
María García-Martínez, Santiago Martínez-Isasi, Cristina Varela-Casal, Antonio Rodríguez-Núñez
{"title":"Learning how to activate the chain of survival at school: Impact of an innovative educational intervention in children aged 5 to 8 years","authors":"María García-Martínez, Santiago Martínez-Isasi, Cristina Varela-Casal, Antonio Rodríguez-Núñez","doi":"10.1016/j.anpede.2026.504296","DOIUrl":"10.1016/j.anpede.2026.504296","url":null,"abstract":"<div><h3>Introduction</h3><div>To improve the prognosis of cardiac arrest, annual school-based first aid training is recommended from an early age. However, there is limited scientific evidence supporting specific pedagogical strategies for this purpose. This study evaluated the impact of interactive teaching resources compared with traditional instruction on the acquisition and retention of skills related to activating the chain of survival in schoolchildren aged 5–8 years.</div></div><div><h3>Methods</h3><div>We conducted a quasi-experimental study was conducted in five schools. A total of 298 schoolchildren were included: 111 in the control group (traditional instruction) and 187 in the intervention group (learning with a “never-ending book” and a telephone simulator). Assessments were carried out immediately after training (E0) and at 12 months (E1) using a simulation scenario and a checklist.</div></div><div><h3>Results</h3><div>In the initial assessment (E0), the intervention group achieved superior results in four key variables. At the 12-month evaluation (E1), the intervention group maintained significant advantages in competencies related to activating emergency medical services and effective communication with the dispatcher. The ability to use the phone in hands-free mode declined over time in both groups, while the ability to recall a parental phone number improved.</div></div><div><h3>Conclusions</h3><div>Simple hands-on and interactive resources can improve both the acquisition and retention of basic skills required to activate the chain of survival. Their implementation in schools is feasible, cost-effective, and promotes practical learning from an early age.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504296"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-09-01Epub Date: 2026-09-11DOI: 10.1016/j.anpede.2026.504197
Xavier Bosch-Capblanch
{"title":"Selection bias: concerning “Impact of digital media on development and physical health”","authors":"Xavier Bosch-Capblanch","doi":"10.1016/j.anpede.2026.504197","DOIUrl":"10.1016/j.anpede.2026.504197","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504197"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148931367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-09-01Epub Date: 2026-09-18DOI: 10.1016/j.anpede.2026.504341
Ana Lucía Gómez Gila, Fernando Gómez-Peralta, Susana Pica Montesinos, Virginia Bellido, Roque Cardona-Hernandez, María Asunción Martínez-Brocca
{"title":"Executive summary of the Integrated Clinical care pathway for the detection and management of preclinical stages of type 1 diabetes: SED-SEEN-SEEP consensus","authors":"Ana Lucía Gómez Gila, Fernando Gómez-Peralta, Susana Pica Montesinos, Virginia Bellido, Roque Cardona-Hernandez, María Asunción Martínez-Brocca","doi":"10.1016/j.anpede.2026.504341","DOIUrl":"10.1016/j.anpede.2026.504341","url":null,"abstract":"<div><div>Type 1 diabetes (T1D) can be identified in preclinical stages through the detection of islet autoantibodies and staged before clinical onset. This evolving paradigm highlights the need for structured care models allowing coordinated identification, staging, and follow-up of individuals with positive islet autoimmunity. This document describes an Integrated Care Pathway (ICP) developed from the available scientific evidence and the national SED-SEEN-SEEP consensus on screening and monitoring of preclinical T1D. The model is organised into three core sub-processes (target population identification, autoantibody detection and confirmation, and clinical follow-up with staging) and one transversal support sub-process based on information systems and performance indicators. This ICP provides a structured, evaluable, and scalable framework for the homogeneous implementation of screening and follow-up of preclinical T1D.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504341"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149003190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giulia Greta Dradi, Elena Naz Villalba, Elena Jaime Lara, José Luis López Estebaranz
{"title":"Mosaic trisomy 22: Reaching the diagnosis through the skin","authors":"Giulia Greta Dradi, Elena Naz Villalba, Elena Jaime Lara, José Luis López Estebaranz","doi":"10.1016/j.anpede.2026.504220","DOIUrl":"10.1016/j.anpede.2026.504220","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504220"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-09-01Epub Date: 2026-09-11DOI: 10.1016/j.anpede.2026.504277
Josep de la Flor Bre, Ana Alonso Rubio, Josep Marès Bermúdez, Esther Benitez Rabagliatti, Marisa Ridao Redondo, Mireia Serrano Manzano, Luis Ortiz-González, on behalf of the Working Group on Diagnostic Technologies in Primary Care (TECDIAP) of the Sociedad Española de Pediatría Extrahospitalaria y Atención Primaria (SEPEAP)
{"title":"New diagnostic techniques included in the primary care service portfolio of the Spanish public health system","authors":"Josep de la Flor Bre, Ana Alonso Rubio, Josep Marès Bermúdez, Esther Benitez Rabagliatti, Marisa Ridao Redondo, Mireia Serrano Manzano, Luis Ortiz-González, on behalf of the Working Group on Diagnostic Technologies in Primary Care (TECDIAP) of the Sociedad Española de Pediatría Extrahospitalaria y Atención Primaria (SEPEAP)","doi":"10.1016/j.anpede.2026.504277","DOIUrl":"10.1016/j.anpede.2026.504277","url":null,"abstract":"<div><div>We present the new diagnostic techniques for use in primary care pediatrics, which have been included in the Spanish public health system nationwide portfolio of services, pursuant to the Royal Decree published in the Official State Gazette (BOE) on May 13, 2025. Specifically, the newly included techniques are tympanometry, transcutaneous bilirubin measurement, rapid testing for respiratory viruses, measurement of C-reactive protein in capillary blood, rapid testing for allergies, instrument-based vision screening, dermoscopy, and point-of-care ultrasound.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504277"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148931385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atraumatic limp in a preschool-aged child","authors":"Neus Saloni Gómez, Miren Panigua García, Federico Serván Alcántara","doi":"10.1016/j.anpede.2026.504236","DOIUrl":"10.1016/j.anpede.2026.504236","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504236"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148946194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-09-01Epub Date: 2026-09-08DOI: 10.1016/j.anpede.2026.504317
Mireia García Cuscó, David Molina Herranz, Ana Llorente de la Fuente, Sofía Cuevas-Asturias, Juan Pablo García Iñiguez, Antonio Morales Martinez, Eider Oñate Vergara
{"title":"Basic concepts of mechanical ventilation: Normal breathing pattern","authors":"Mireia García Cuscó, David Molina Herranz, Ana Llorente de la Fuente, Sofía Cuevas-Asturias, Juan Pablo García Iñiguez, Antonio Morales Martinez, Eider Oñate Vergara","doi":"10.1016/j.anpede.2026.504317","DOIUrl":"10.1016/j.anpede.2026.504317","url":null,"abstract":"<div><div>Mechanical ventilation is a cornerstone in the management of critically ill pediatric patients, ensuring adequate gas exchange and reducing the work of breathing. Its appropriate use requires a solid understanding of respiratory physiology, lung mechanics, and patient–ventilator interaction.</div><div>This article reviews the basic concepts of mechanical ventilation, including respiratory system anatomy and physiology, as well as key mechanical properties (compliance, resistance, and time constant) that determine respiratory dynamics. Ventilatory modes are classified according to control variable, breath sequence, and targeting scheme, facilitating their interpretation and clinical application.</div><div>Initial ventilator settings are described, emphasizing the importance of lung protective strategies. The article also addresses comprehensive monitoring, based on the systematic assessment of the patient, the ventilator, and the clinical response. Finally, the interpretation of ventilator waveforms is reviewed as a key tool for identifying asynchronies, changes in lung mechanics, and potential complications.</div><div>A thorough understanding of these principles is essential to optimize ventilatory support, improve clinical outcomes, and minimize ventilator-induced lung injury.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504317"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148914760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-09-01Epub Date: 2026-09-15DOI: 10.1016/j.anpede.2026.504377
María Angustias Salmerón-Ruiz, Cristina García de Ribera, Valero Sebastián Barberán, Lefa Eddy-Ives, Julio Alvarez-Pitti, en representación del Comité de Promoción de la Salud Asociación Española de Pediatría Madrid España
{"title":"Selection bias: concerning “Impact of digital media on development and physical health.” Authors reply","authors":"María Angustias Salmerón-Ruiz, Cristina García de Ribera, Valero Sebastián Barberán, Lefa Eddy-Ives, Julio Alvarez-Pitti, en representación del Comité de Promoción de la Salud Asociación Española de Pediatría Madrid España","doi":"10.1016/j.anpede.2026.504377","DOIUrl":"10.1016/j.anpede.2026.504377","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504377"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}