Sabina Bona Gazol, Ainhoa Jiménez Olmos, Laura Valour, Daniel Palanca Arias
{"title":"Pediatric botulism: A mimic for Miller Fisher syndrome.","authors":"Sabina Bona Gazol, Ainhoa Jiménez Olmos, Laura Valour, Daniel Palanca Arias","doi":"10.1016/j.anpede.2026.504278","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504278","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504278"},"PeriodicalIF":0.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandra Musioł, Jan Stanisław Bukowski, Przemysław Bombiński, Aleksandra Banaszkiewicz
{"title":"Fatty pancreas and chronic pancreatitis: A rare association in well-nourished children.","authors":"Aleksandra Musioł, Jan Stanisław Bukowski, Przemysław Bombiński, Aleksandra Banaszkiewicz","doi":"10.1016/j.anpede.2026.504344","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504344","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504344"},"PeriodicalIF":0.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nerea Valles-Murcia, Laura Torrejón-Rodriguez, Alba Cayuela-Hernández, Raquel Escrig, Alba González-Timoneda, Máximo Vento, Álvaro Solaz-García
{"title":"Delayed umbilical cord clamping and fraction of inspired oxygen in preterm infants: implications for postnatal stabilization.","authors":"Nerea Valles-Murcia, Laura Torrejón-Rodriguez, Alba Cayuela-Hernández, Raquel Escrig, Alba González-Timoneda, Máximo Vento, Álvaro Solaz-García","doi":"10.1016/j.anpede.2026.504343","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504343","url":null,"abstract":"<p><p>The transition to extrauterine life involves profound respiratory and hemodynamic changes that enable the shift from transplacental to pulmonary gas exchange and the conversion of fetal circulation to neonatal circulation. In recent years, important modifications have been introduced in delivery room stabilization strategies, particularly regarding umbilical cord management and the initial fraction of inspired oxygen (FiO₂) in preterm infants. The aim of this review is to analyze the available evidence on delayed umbilical cord clamping, ventilation with an intact umbilical cord, and initial oxygen strategies during postnatal stabilization. We performed a narrative review of the recent scientific literature, including experimental studies, clinical trials, and meta-analyses evaluating the impact of these interventions in term and preterm newborns during early neonatal transition. Delayed cord clamping allows additional placental transfusion, increasing the circulating blood volume, improving ventricular preload, and promoting a more stable cardiovascular transition. These effects are associated with earlier stabilization of heart rate and oxygen saturation, as well as reduced supplemental oxygen requirements. Ventilation with an intact umbilical cord allows initiation of respiration while maintaining placental hemodynamic support, facilitating a more gradual cardiorespiratory transition. In addition, recent evidence suggests that initial FiO₂ levels above 0.30 may facilitate achieving the target oxygen saturation in the first minutes of life, particularly in extremely preterm infants.</p>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504343"},"PeriodicalIF":0.0,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Pujol Teixidor, Laura Escalante Coscojuela, Vanessa Laveglia, Pere Sala Castellví
{"title":"Urinary retention as a symptom of acute disseminated encephalomyelitis.","authors":"Laura Pujol Teixidor, Laura Escalante Coscojuela, Vanessa Laveglia, Pere Sala Castellví","doi":"10.1016/j.anpede.2026.504314","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504314","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504314"},"PeriodicalIF":0.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Víctor Manuel Navas-López, Marta Herrador-López, Ramón Cancho Candela, José Luis Peña Segura, Ruth García Romero, Juan José Díaz Martín
{"title":"Feeding ability, dietary intake, and gastrostomy satisfaction in children with cerebral palsy: An observational study.","authors":"Víctor Manuel Navas-López, Marta Herrador-López, Ramón Cancho Candela, José Luis Peña Segura, Ruth García Romero, Juan José Díaz Martín","doi":"10.1016/j.anpede.2026.504368","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504368","url":null,"abstract":"<p><strong>Objectives: </strong>Cerebral palsy (CP) often causes motor impairment and comorbidities, including gastrointestinal problems that contribute to undernutrition. This study characterizes feeding capabilities and nutritional needs in Spanish children with CP.</p><p><strong>Methods: </strong>We conducted a multicenter observational study in 10 Spanish hospitals in pediatric patients (4-14 years) with CP classified according to Gross Motor Function Classification System (GMFCS) level. We collected data on sociodemographic, anthropometric, and nutritional variables. We used the Eating and Drinking Ability Classification System (EDACS) to assess feeding and drinking dysfunction, and the Structured Satisfaction with Gastrostomy Feeding (SAGA-8) questionnaire to assess caregiver satisfaction.</p><p><strong>Results: </strong>A total of 112 patients (median age, 9 years; IQR, 7-11 years) were included; 70.5% had GMFCS levels IV-V. Most patients (77.7%) received oral feeding, and oral nutritional supplementation increased with GMFCS severity. The EDACS distribution differed significantly in relation to the GMFCS level, as did the total energy intake, energy expenditure, and daily protein and fat intakes. The dietary intake of vitamin D and selenium and the serum vitamin B12 concentration also differed significantly by GMFCS level. Approximately 80% of caregivers reported high satisfaction with gastrostomy feeding (SAGA-8).</p><p><strong>Conclusion: </strong>Children with CP differ in feeding ability, energy expenditure, and macronutrient and micronutrient intake in relation to the GMFCS level. Caregivers perceive gastrostomy as a helpful and satisfactory nutritional support strategy.</p>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504368"},"PeriodicalIF":0.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Javier Alvarez Aldeán, Francisco José Alvarez García, Fernando Baquero Artigao, Marta Cruz Cañete, María Fernández Prada, Laura Francisco González, Ana María Grande Tejada, Antonio Iofrío de Arce, Alejandra Méndez Sánchez, Fernando Moraga Llop, Ignacio Salamanca de la Cueva
{"title":"Influenza vaccination in childhood and adolescence. Evaluation of the 2025-2026 campaign in Spain and improvement strategies. Report by AEV, CAV-AEP and SEIP.","authors":"Javier Alvarez Aldeán, Francisco José Alvarez García, Fernando Baquero Artigao, Marta Cruz Cañete, María Fernández Prada, Laura Francisco González, Ana María Grande Tejada, Antonio Iofrío de Arce, Alejandra Méndez Sánchez, Fernando Moraga Llop, Ignacio Salamanca de la Cueva","doi":"10.1016/j.anpede.2026.504373","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504373","url":null,"abstract":"<p><p>Seasonal influenza represents a significant burden in childhood. This article analyzes pediatric influenza vaccination during the 2025-2026 campaign, as well as epidemiological, effectiveness, and preliminary vaccination coverage data. Routine vaccination against influenza between ages 6 and 59 months, as well as the extension of the recommendation up to 17 years, as outlined in the 2025 AEV, CAV-AEP, and SEIP consensus document, is key to individual and collective protection. We propose advancing further in developing effective strategies to continue increasing vaccination coverage, as well as expanding the age range for vaccination, as has already been implemented in some autonomous communities in 2025-2026.</p>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504373"},"PeriodicalIF":0.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Itziar Iturralde Orive, Javier Álvarez Aldean, Ana Mª Grande-Tejada, Fernando Moraga LLop
{"title":"The grey zone of influenza vaccination: children with risk conditions still lack their own data.","authors":"Itziar Iturralde Orive, Javier Álvarez Aldean, Ana Mª Grande-Tejada, Fernando Moraga LLop","doi":"10.1016/j.anpede.2026.504339","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504339","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504339"},"PeriodicalIF":0.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Isabel Turrión Nieves, Cristina Sobrino Garijo, Belén Miguel Ibañez, Rafael Martín Holguera
{"title":"Efficacy of second-line therapeutic strategies in patients with chronic nonbacterial osteomyelitis refractory to NSAIDs: A systematic review.","authors":"Ana Isabel Turrión Nieves, Cristina Sobrino Garijo, Belén Miguel Ibañez, Rafael Martín Holguera","doi":"10.1016/j.anpede.2026.504350","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504350","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy and safety of second-line therapies in pediatric patients with chronic nonbacterial osteomyelitis (CNO) that responded poorly to nonsteroidal anti-inflammatory drugs (NSAIDs).</p><p><strong>Methods: </strong>A systematic review of observational studies, cohort studies, and case series (n = 13) involving patients aged less than 15 years with a diagnosis of CNO. We analyzed clinical and radiological remission rates, safety profiles, and the incidence of adverse events for the different therapeutic regimens.</p><p><strong>Results: </strong>The efficacy of NSAIDs in monotherapy was limited (18%-57%). Among second-line therapies, bisphosphonates (particularly pamidronate) and tumor necrosis factor-α inhibitors (TNF inhibitors) achieved the highest response rates, with remission levels between 70% and 91%. Pamidronate proved highly effective for spinal lesions, achieving rapid pain resolution. TNF inhibitors were particularly effective in refractory cases and for the prevention of long-term relapses. The efficacy of disease-modifying antirheumatic drugs (DMARDs) was lower and inconsistent (12%-50%). No serious adverse effects were reported; the most frequent event was flu-like syndrome following the first pamidronate infusion.</p><p><strong>Conclusions: </strong>Bisphosphonates and TNF inhibitors constitute the most effective and safe second-line strategies for the treatment of refractory CNO. Early diagnosis and appropriate therapeutic scaling are essential to achieve complete remission and prevent permanent bone sequelae, such as spinal fractures or deformities.</p>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504350"},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Domingos Carlos Mirione, María Rúa-Alonso, Anelise Reis Gaya, Nuria Garatachea
{"title":"Active commuting in adolescents in northern Mozambique: Influence of the context.","authors":"Domingos Carlos Mirione, María Rúa-Alonso, Anelise Reis Gaya, Nuria Garatachea","doi":"10.1016/j.anpede.2026.504351","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504351","url":null,"abstract":"<p><strong>Introduction: </strong>Active commuting to school is one of the most effective and cost-efficient strategies for increasing physical activity levels and advancing toward the recommendations for physical activity in adolescents of the World Health Organization.</p><p><strong>Methods: </strong>This study analyzed the prevalence of active commuting to school among adolescents in northern Mozambique in relation to sex, age, and area of residence (province and type of setting) through the administration of the Active Transport and Physical Activity Assessment Tool for African School Children questionnaire to 919 adolescents aged 13-17 from the provinces of Nampula, Cabo Delgado, and Niassa.</p><p><strong>Results: </strong>Overall, 88.6% of adolescents actively commuted to school (either on foot or by bicycle), with no significant differences by sex or age. However, there were variations based on place of residence, with a prevalence of 98% in rural areas compared to 77.7% in urban areas; Niassa had the highest rates of active commuting compared to the other provinces.</p><p><strong>Discussion: </strong>Active commuting is the most common mode of travel to school among adolescents in northern Mozambique, although this appears to be driven more by a lack of alternatives than by a deliberate health-conscious choice. Therefore, it is imperative that authorities design intersectoral public policies to promote safe environments and improve travel conditions for adolescents in northern Mozambique.</p>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504351"},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}