Rachid Bouchikh-El Jarroudi, Hugo González-Valdivia, Mariana Planells-Alduvín, Mariana Alvarez-Vukov
{"title":"Infantile orbital hemangioma: A case report.","authors":"Rachid Bouchikh-El Jarroudi, Hugo González-Valdivia, Mariana Planells-Alduvín, Mariana Alvarez-Vukov","doi":"10.1016/j.anpede.2025.503967","DOIUrl":"https://doi.org/10.1016/j.anpede.2025.503967","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"503967"},"PeriodicalIF":0.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Sun, Ya Xiao, Shu-Qin Jiang, Hong-Ru Zhang, Jin-Bo Li, Wen-Hui Shi, Wei Wang
{"title":"The correlation between the vitamin D/insulin ratio and central precocious puberty in girls and its screening potential.","authors":"Jun Sun, Ya Xiao, Shu-Qin Jiang, Hong-Ru Zhang, Jin-Bo Li, Wen-Hui Shi, Wei Wang","doi":"10.1016/j.anpede.2025.504016","DOIUrl":"https://doi.org/10.1016/j.anpede.2025.504016","url":null,"abstract":"<p><strong>Introduction: </strong>There are still no effective biomarkers for the diagnosis of central precocious puberty (CPP), and single metabolic indicators (such as vitamin D or insulin) are susceptible to interference from metabolic interactions. We conducted a study to assess the correlation between the vitamin D/insulin ratio (VDIR) and CPP and the screening potential of the VDIR.</p><p><strong>Methods: </strong>Case-control study in a sample of 170 girls aged 6-10 years, including 85 girls with CPP and 85 girls with normal growth and development. We collected data on growth and developmental indicators and laboratory test results for both groups. The association between the VDIR and CPP/gonadal development was assessed by means of multivariate logistic and linear regression analyses. The diagnostic value of VDIR was evaluated by means of receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>The VDIR in the CPP group was lower than in the control group (3.45 vs 6.18). The area under the ROC curve (AUC) of the VDIR for diagnosis of CPP was 0.731, with a sensitivity of 70.59% and a specificity of 67.06%, higher compared to vitamin D alone (AUC = 0.682) or insulin alone (AUC = 0.690). The multivariate logistic/linear regression analysis revealed that for every 1-unit increase in VDIR, there was a 0.814-fold decrease in the risk of CPP and a 233.54 mm<sup>3</sup> decrease in uterine volume.</p><p><strong>Conclusion: </strong>By integrating the metabolic interactions between vitamin D and insulin, VDIR shows promising value in assessing the risk of CPP. As a potential biomarker, it may offer dual clinical value by enabling early screening of high-risk individuals prior to the definitive diagnosis, as well as providing guidance for personalized interventions.</p>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504016"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joana Azevedo Silva, Raquel Santos, Ana Rita Batista, Mafalda Cascais
{"title":"Neonatal intraoral papulovesicular lesions: A rare manifestation of a common condition.","authors":"Joana Azevedo Silva, Raquel Santos, Ana Rita Batista, Mafalda Cascais","doi":"10.1016/j.anpede.2025.503969","DOIUrl":"https://doi.org/10.1016/j.anpede.2025.503969","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"503969"},"PeriodicalIF":0.0,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Bachiller-Carnicero, Lucía Torres Aguilar, María Carmen Torres Hinojal
{"title":"Relation between infant sleep, parental stress and co-sleeping at two years of age","authors":"Luis Bachiller-Carnicero, Lucía Torres Aguilar, María Carmen Torres Hinojal","doi":"10.1016/j.anpede.2025.503970","DOIUrl":"10.1016/j.anpede.2025.503970","url":null,"abstract":"<div><h3>Introduction</h3><div>Parental stress may contribute to neurodevelopmental disorders in children, and lack of sleep may be at the root of the issue. The aim of our study was to assess the association between infant sleep and parental stress, as well as the influence of socioeconomic factors or co-sleeping.d</div></div><div><h3>Material and methods</h3><div>We conducted a prospective observational study in children aged 2 years. Parents completed three questionnaires: the Parenting Stress Index-4-Short Form (PSI), the Brief Infant Sleep Questionnaire and a questionnaire that assessed socioeconomic and sleep-related variables.</div></div><div><h3>Results</h3><div>The sample included 109 families. The median (interquartile range) duration of nighttime sleep, time spent awake at night and sleep onset latency (in minutes) and number of nocturnal awakenings in the children were 500 (447.5–602.5), 15 (5–60); 1 (0–3) and 10 (8–20), respectively. The mean total score in the PSI was 61.1 (SD, 12.3).</div><div>The correlation between the PSI total score and the minutes of nighttime sleep was: 0.478 (<em>P</em> = .001), and we found a significant increase in the PSI total score when nighttime sleep duration in the child was less than 540<!--> <!-->min, mainly on account of the dysfunctional parent-child interaction and difficult child subscales.</div><div>Parental stress was increased significantly with the practice of co-sleeping and with parental age less than 20 years or more than 40 years. Co-sleeping was associated with shorter nighttime sleep duration, more time awake at night and an increased number of nocturnal awakenings.</div></div><div><h3>Conclusions</h3><div>Decreased infant sleep duration at night caused an increase in parental stress. Likewise, co-sleeping and early or advanced parenthood are associated with a higher level of stress.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 3","pages":"Article 503970"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145002187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Ochoa Sangrador , Eduardo Ortega Páez , Manuel Molina Arias , Fernando Carvajal Encina , Eduardo Cuestas Montañes
{"title":"Frequency, risk and impact measures in epidemiology","authors":"Carlos Ochoa Sangrador , Eduardo Ortega Páez , Manuel Molina Arias , Fernando Carvajal Encina , Eduardo Cuestas Montañes","doi":"10.1016/j.anpede.2025.503877","DOIUrl":"10.1016/j.anpede.2025.503877","url":null,"abstract":"<div><div>The results of epidemiological studies should be expressed in terms of measures of health or disease. This article reviews the key frequency, risk and impact measures, which can be estimated using proportions, ratios or rates, depending on the specific context. It discusses which measures are appropriate for a study based on its design. Cross-sectional studies serve to estimate the prevalence; cohort studies allow calculation of the incidence, relative risk and attributable fractions; case-control studies use the odds ratio and clinical trials determine the relative risk, absolute and relative risk reductions and number needed to treat (NNT). The article also outlines criteria for the interpretation of these measures, supported by specific examples.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 3","pages":"Article 503877"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hepatopulmonary fusion associated with right diaphragmatic hernia in a newborn","authors":"Verónica Castro Palaguachi, Marjorie Rodríguez-Guerrero, Luis Marcano Sanz, Miurkis Endis Miranda, Lenín Quezada Méndez","doi":"10.1016/j.anpede.2025.503943","DOIUrl":"10.1016/j.anpede.2025.503943","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 3","pages":"Article 503943"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Begoña Pérez-Moneo , M. Jesús Esparza Olcina , Sergio Flores Villar , Carolina Blanco Rodríguez , M. Victoria Martínez Rubio , Manuel Molina Arias , Comité de Trabajo de Pediatría Basada en la Evidencia
{"title":"Methodology for research and scientific publication in pediatrics. Main methodological designs","authors":"Begoña Pérez-Moneo , M. Jesús Esparza Olcina , Sergio Flores Villar , Carolina Blanco Rodríguez , M. Victoria Martínez Rubio , Manuel Molina Arias , Comité de Trabajo de Pediatría Basada en la Evidencia","doi":"10.1016/j.anpede.2025.503933","DOIUrl":"10.1016/j.anpede.2025.503933","url":null,"abstract":"<div><div>Epidemiology is a fundamental discipline in medical research, as it examines the distribution and determinants of diseases within populations. To achieve this, it employs various research designs, which are broadly classified into observational and experimental studies. Observational studies include descriptive studies, such as case series and cross-sectional studies, as well as analytical studies, such as cohort and case-control studies, which assess associations between exposures and health outcomes. Experimental studies, particularly randomized controlled trials, establish causal relationships. The choice of study design depends on the research question, feasibility and available resources.</div><div>It is essential to understand their characteristics, the contexts in which they should be applied and the most common sources of bias to ensure the accurate interpretation of results.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 3","pages":"Article 503933"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The child’s right to be cared for: A humane option in the euthanasia debate","authors":"Pedro J. Alcalá Minagorre , Ricardo Martino Alba","doi":"10.1016/j.anpede.2025.503911","DOIUrl":"10.1016/j.anpede.2025.503911","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 3","pages":"Article 503911"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}