Raquel Torres-Luna , María Carmen Sellán Soto , Francisco Reinoso-Barbero
{"title":"Analgesic efficacy of clinical hypnosis in pediatric patients following orthopedic surgery","authors":"Raquel Torres-Luna , María Carmen Sellán Soto , Francisco Reinoso-Barbero","doi":"10.1016/j.anpede.2025.503831","DOIUrl":"10.1016/j.anpede.2025.503831","url":null,"abstract":"<div><h3>Introduction</h3><div>Clinical hypnosis is effective for pain management in adults, but there is little evidence of its use in the pediatric population.</div></div><div><h3>Materials and Methods</h3><div>We conducted a randomized clinical trial on pediatric patients (aged 7–19 years) that had undergone major orthopedic surgery, allocated to one of two groups: the experimental hypnosis group (HG), which received two sessions of clinical hypnosis, or the control group (CG), which had two non-hypnosis visits. The variables analyzed were pain (Visual Analog Scale [VAS]), use of analgesic drugs, anxiety (State-Trait Anxiety Inventory for Children [STAIC]), parasympathetic activation (Analgesia Nociception Index [ANI] monitor) and vital signs such as heart rate (HR), respiratory rate (RR) and systolic and diastolic blood pressure (SBP and DBP). We used the Student <em>t</em> test and the χ<sup>2</sup> test for the statistical analysis.</div></div><div><h3>Results</h3><div>Of the 24 patients in the sample, 16 were assigned to the HG and 8 to the CG. In the HG, we observed a significant reduction in VAS scores at 24 h (<em>P</em> = .0001) and 48 h (<em>P</em> = .0004) post surgery. Additionally, HG patients required fewer rescue doses of analgesic agents (<em>P</em> = .025) and had lower state-anxiety scale scores in the STAIC (<em>P</em> = .046). The ANI values increased significantly at 24 h (<em>P</em> = .0001) and 48 h (<em>P</em> = .007). The HR, SBP and DBP values decreased at 24 h (<em>P</em> < .05), and the RR at 24 and 48 h (<em>P</em> < .05).</div></div><div><h3>Conclusion</h3><div>Clinical hypnosis is an effective nonpharmacological intervention for reducing postoperative pain and anxiety in children, and it is associated with an increase in parasympathetic tone.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 4","pages":"Article 503831"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María López Blázquez , María Ángeles Espinosa Castro , Reyes Álvarez García-Rovés , Miriam Centeno Jiménez , Ana Isabel Fernández Ávila , Francisco Javier Bermejo Thomas , Constancio Medrano López
{"title":"Prognostic role of novel variables in sudden cardiac death risk associated to hypertrophic cardiomyopathy","authors":"María López Blázquez , María Ángeles Espinosa Castro , Reyes Álvarez García-Rovés , Miriam Centeno Jiménez , Ana Isabel Fernández Ávila , Francisco Javier Bermejo Thomas , Constancio Medrano López","doi":"10.1016/j.anpede.2025.503814","DOIUrl":"10.1016/j.anpede.2025.503814","url":null,"abstract":"<div><h3>Introduction</h3><div>Models for estimating the risk of sudden cardiac death (SCD) in pediatric hypertrophic cardiomyopathy (HCM) used in our setting do not consider some parameters of routine clinical practice. The objective was to identify non-classical risk factors and evaluate their prognostic value.</div></div><div><h3>Patients and methods</h3><div>Retrospective observational study, including patients with isolated HCM 0-18 years old, evaluating clinical, genetic, and imaging variables. The risk of SCD or major arrhythmic cardiac events (MACEs) was estimated according to the three most widely used European models (HCM Risk-SCD, European Society of Cardiology [ESC] algorithm, and HCM Risk-Kids), analyzing their predictive capacity by adding genotyping and advanced cardiac imaging parameters.</div></div><div><h3>Results</h3><div>The sample included 77 patients followed up for 5.25 years. Ten (13%) experienced a MACE. We found that MACE was significantly associated with myocardial deformation and positive genotype status, and associated, although not significantly, to late gadolinium enhancement (LGE) in cardiac MRI (<em>P</em> = .062). Events were more frequent (hazard ratio = 18.5; <em>P</em> = .006) and occurred earlier (<em>P</em> = .022) in association with variants in genes other than <em>MYBPC3</em>. The inclusion of “genotype other than <em>MYBPC3</em>” and “presence of LGE” improved the predictive capacity of the models for the high-risk (C-statistic 0.94 vs 0.84 with HCM Risk-SCD; 0.88 vs 0.74 with ESC algorithm; 0.90 vs 0.80 with HCM Risk-Kids) and intermediate-risk categories (C-statistic 0.88 vs 0.51 with HCM Risk-SCD; 0.85 vs 0.64 with ESC algorithm; 0.84 vs 0.51 with HCM Risk-Kids).</div></div><div><h3>Conclusions</h3><div>The predictive capacity of European risk models improves by incorporating the variables “genotype other than <em>MYBPC3</em>” and “presence of LGE”, although larger studies are required to validate their prognostic value.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 4","pages":"Article 503814"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ignacio del Castillo Velilla , María Solsona Gadeaz , Edurne Sarrate Garcia , Aida Felipe Villalobos
{"title":"Craniofacial lession as a presentation of idiopathic purpura fulminans","authors":"Ignacio del Castillo Velilla , María Solsona Gadeaz , Edurne Sarrate Garcia , Aida Felipe Villalobos","doi":"10.1016/j.anpede.2025.503765","DOIUrl":"10.1016/j.anpede.2025.503765","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 4","pages":"Article 503765"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marina Romero Bravo , José Antonio Llamas Carmona , Elisabeth Gómez Moyano , Juan María García-Hirschfeld
{"title":"Infantile digital fibromatosis: A clinical case report","authors":"Marina Romero Bravo , José Antonio Llamas Carmona , Elisabeth Gómez Moyano , Juan María García-Hirschfeld","doi":"10.1016/j.anpede.2025.503704","DOIUrl":"10.1016/j.anpede.2025.503704","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 4","pages":"Article 503704"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alba Mateu Gallardo , Susanna Hernández Bou , Ana I. Curcoy Barcenilla , Laia Álvarez Bota , Victoria Trenchs Sainz de la Maza
{"title":"SARS-CoV-2 infection in neonates attended in the emergency department","authors":"Alba Mateu Gallardo , Susanna Hernández Bou , Ana I. Curcoy Barcenilla , Laia Álvarez Bota , Victoria Trenchs Sainz de la Maza","doi":"10.1016/j.anpede.2025.503750","DOIUrl":"10.1016/j.anpede.2025.503750","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 3","pages":"Article 503750"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roi Piñeiro Pérez , Sonsoles Galán Arévalo , Milagros Risso , Inmaculada Hidalgo Montes , Alejandro López-Escobar
{"title":"Reluctance of parents to immunize their children with nirsevimab","authors":"Roi Piñeiro Pérez , Sonsoles Galán Arévalo , Milagros Risso , Inmaculada Hidalgo Montes , Alejandro López-Escobar","doi":"10.1016/j.anpede.2025.503743","DOIUrl":"10.1016/j.anpede.2025.503743","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 3","pages":"Article 503743"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}