Anales de pediatria最新文献

{"title":"Active commuting in adolescents in northern Mozambique: Influence of the context.","authors":"Domingos Carlos Mirione, María Rúa-Alonso, Anelise Reis Gaya, Nuria Garatachea","doi":"10.1016/j.anpede.2026.504351","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504351","url":null,"abstract":"<p><strong>Introduction: </strong>Active commuting to school is one of the most effective and cost-efficient strategies for increasing physical activity levels and advancing toward the recommendations for physical activity in adolescents of the World Health Organization.</p><p><strong>Methods: </strong>This study analyzed the prevalence of active commuting to school among adolescents in northern Mozambique in relation to sex, age, and area of residence (province and type of setting) through the administration of the Active Transport and Physical Activity Assessment Tool for African School Children questionnaire to 919 adolescents aged 13-17 from the provinces of Nampula, Cabo Delgado, and Niassa.</p><p><strong>Results: </strong>Overall, 88.6% of adolescents actively commuted to school (either on foot or by bicycle), with no significant differences by sex or age. However, there were variations based on place of residence, with a prevalence of 98% in rural areas compared to 77.7% in urban areas; Niassa had the highest rates of active commuting compared to the other provinces.</p><p><strong>Discussion: </strong>Active commuting is the most common mode of travel to school among adolescents in northern Mozambique, although this appears to be driven more by a lack of alternatives than by a deliberate health-conscious choice. Therefore, it is imperative that authorities design intersectoral public policies to promote safe environments and improve travel conditions for adolescents in northern Mozambique.</p>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504351"},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analytical differences in patients with PFAPA during an episode versus an asymptomatic state, beyond acute-phase reagents. A multicenter paired samples study.","authors":"Mara Rodríguez Ortiz, Sara Murias Loza, María Garrido Martín, Clara Udaondo Gascón, Julián Rodríguez Suárez","doi":"10.1016/j.anpede.2026.504349","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504349","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504349"},"PeriodicalIF":0.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149129373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is it time to reconsider routine intubation in mild congenital diaphragmatic hernia?","authors":"Jorge L Alvarado Socarras, Delia Theurel Martin","doi":"10.1016/j.anpede.2026.504334","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504334","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504334"},"PeriodicalIF":0.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149120092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unintentional poisonings by household products in pediatric emergency departments in Spain.","authors":"Johanna Ramírez-Romero, Beatriz Azkunaga, Santiago Mintegi","doi":"10.1016/j.anpede.2026.504337","DOIUrl":"https://doi.org/10.1016/j.anpede.2026.504337","url":null,"abstract":"<p><strong>Introduction: </strong>Household products are a frequent cause of unintentional poisoning in children under 7 years of age. However, very few studies analyze their characteristics. The objective of our study was to analyze the typology, epidemiology, interventions, and outcomes of cases of unintentional poisoning by household products managed in pediatric emergency departments (PEDs) in Spain.</p><p><strong>Methods: </strong>Observational study based on the prospective registry of the Toxicology Observatory of the Poisoning Working Group of the Spanish Society of Pediatric Emergency Medicine (SEUP), including 58 PEDs. We analyzed cases registered between 2008 and 2025.</p><p><strong>Results: </strong>Of the 3900 registered poisonings, 726 (18.6%) corresponded to unintentional ingestion of household products in children under 7 years of age. The median age was 24 months (interquartile range, 16-35), 57% were male, and 94% of the episodes occurred at home, primarily in the kitchen (318 cases; 74.6%). Household products were the main group of toxic substances involved in children aged 12-20 months. Caustics were the most frequently involved type of product (214 cases [29.5%]; bleach was the most frequent individual agent, involved in 159 cases [21.9%]), and poisoning by caustic substances was significantly associated with storage in nonoriginal containers and within reach of children, as well as with a higher proportion of symptoms, additional tests, and endoscopies. No patients died. Esophageal caustic burns were documented in 6 patients (0.82%), all of them after ingestion of caustics (2.8% of this group).</p><p><strong>Conclusions: </strong>Unintentional ingestion of household products is the leading cause of poisoning in children aged 12-20 months managed in Spanish emergency departments. The implementation of effective prevention strategies, especially regarding caustic substances, is urgently needed.</p>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":" ","pages":"504337"},"PeriodicalIF":0.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148979017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new therapeutic era in childhood and adolescent obesity: opportunities and future challenges","authors":"Molina-Giraldo Paula,&nbsp;Suárez-Ortega Larisa,&nbsp;Ramon-Krauel Marta","doi":"10.1016/j.anpede.2026.504194","DOIUrl":"10.1016/j.anpede.2026.504194","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504194"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148889765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective observational study on pain identification and management in a pediatric hospital-at-home unit","authors":"Ana María Angulo Chacón,&nbsp;Teresa Eizaguirre Fernández-Palacios,&nbsp;Nuria Pedruelo Reyes,&nbsp;María Isabel González Sánchez,&nbsp;Blanca Toledo del Castillo,&nbsp;Alicia Fernández González,&nbsp;Rosa Rodríguez Fernández","doi":"10.1016/j.anpede.2026.504316","DOIUrl":"10.1016/j.anpede.2026.504316","url":null,"abstract":"<div><h3>Introduction</h3><div>Pain assessment is an essential component of the evaluation of pediatric patients. In the context of home hospitalization, pain management poses a clinical challenge, as it requires active participation from caregivers and must be supported by adequate training. The main objective of this study was to describe the identification, assessment, and management of pain in a hospital-at-home unit after the implementation of a protocol.</div></div><div><h3>Materials and methods</h3><div>We conducted a prospective, observational, and descriptive study following the implementation of a pain management protocol. The sample included all patients admitted to the unit. The following variables were assessed: the ability of the caregiver to identify and manage pain, and the approach to pain management during painful procedures performed at home.</div></div><div><h3>Results</h3><div>The study included a total of 309 care episodes corresponding to 198 patients. Pain was adequately documented in 264 cases (85.4%). We found near-perfect agreement between caregiver- and provider-reported pain assessments (κ = 0.96; <em>P</em> &lt; .001). Pain was identified in 31 procedures (10.0%). The median length of stay was significantly longer among patients with pain compared to those without pain (8 days [IQR, 5–13] vs 4 days [IQR, 2–5]; <em>P</em> &lt; .01). Only three patients (1%) required hospital readmission due to poor pain control. A total of 32 painful procedures were performed, and some type of analgesic strategy was used in all of them: nonpharmacological measures in 12 patients and topical analgesia combined with nonpharmacological strategies in 19.</div></div><div><h3>Conclusions</h3><div>Pediatric pain management at home appears feasible and effective through structured protocols that include caregiver participation and appropriate training. The high compliance rate and minimal discrepancy between caregiver and health care staff assessments suggest that the model is safe and well-accepted by both caregivers and professionals.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504316"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What do those who vaccinate think? Perception of the flu among pediatrician and pediatric nursing professionals","authors":"Ángel Valls Arévalo,&nbsp;Javier Álvarez Aldeán,&nbsp;Franciso José Álvarez García,&nbsp;Elisa Garrote Llanos,&nbsp;Antonio Iofrío de Arce,&nbsp;Lucía López Granados,&nbsp;María Luisa Navarro Gómez,&nbsp;Valentín Pineda Solas,&nbsp;Irene Rivero Calle,&nbsp;Jesús Ruiz-Contreras,&nbsp;Ignacio Salamanca de la Cueva,&nbsp;Pepe Serrano Marchuet,&nbsp;on behalf of the Advisory Committee on Vaccines of the Asociación Española de Pediatría (CAV-AEP)","doi":"10.1016/j.anpede.2026.504338","DOIUrl":"10.1016/j.anpede.2026.504338","url":null,"abstract":"<div><h3>Introduction</h3><div>Childhood influenza represents a significant healthcare burden, in terms of both primary care and hospital emergency department visits, as well as in hospitalizations. The objective of this study was to analyze the perceptions of pediatricians and nurses working in pediatric settings regarding childhood influenza and influenza vaccination, as well as the perceived barriers, in order to identify new strategies to improve vaccination coverage.</div></div><div><h3>Materials and methods</h3><div>Cross-sectional, observational, and descriptive study through a nationwide survey of pediatricians and pediatric nurses. We collected data on variables related to perceived severity, clinical burden, complications, vaccination, training, family reluctance to vaccinate, and preferred communication channels.</div></div><div><h3>Results</h3><div>A total of 2268 professionals responded: 1877 pediatricians and 391 nurses. Eighty-five percent of pediatricians believed influenza had a significant impact on their clinical practice, and 91% identified it as potentially serious in childhood. The most frequently perceived complications were otitis media, bronchitis/bronchiolitis, and pneumonia. Ninety-five percent of pediatricians supported vaccination against influenza for children aged 6–59 months of age (childhood vaccination), with chronic illnesses, or living with at-risk individuals, and 97% perceived its extension up to age 17 positively. However, 33% expressed uncertainty about vaccine effectiveness. Sixty-seven percent of pediatricians reported frequent reluctance among families, and 82% of nurses considered that families do not perceive influenza as a serious illness.</div></div><div><h3>Conclusions</h3><div>There is broad professional consensus regarding the clinical relevance of childhood influenza and the positive value of vaccination. The main barrier identified is the low risk perception among families, along with a need for training on vaccine effectiveness and communication with families. Strategies based on educational materials with visual contents, brief information, and a focus on the actual risk could improve both of these aspects.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504338"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulation and analysis of the access to orphan drugs in the pediatric population in Spain","authors":"Paula del Río Gómez,&nbsp;Sandra Caíña López,&nbsp;María del Carmen Dávila Pousa","doi":"10.1016/j.anpede.2026.504315","DOIUrl":"10.1016/j.anpede.2026.504315","url":null,"abstract":"<div><h3>Introduction</h3><div>Between 70% and 80% of rare diseases are of genetic origin, so most of them have onset during childhood. They share common features, including delayed or absent diagnosis; being severe, chronic, and disabling; lack of effective treatments; and insufficient knowledge or awareness among health care professionals and society at large. Their management frequently requires specific treatment with orphan drugs. However, the development of pediatric orphan drugs and their accessibility continue to be limited. The aim of this study was to describe the situation of pediatric orphan drugs in Spain as of December 31, 2025.</div></div><div><h3>Methods</h3><div>Cross-sectional descriptive study based on the review of the scientific literature and regulatory databases between 2013 and 2025. We identified all the orphan drugs included in the CIMA database of the Spanish Agency of Medicines and Medical Devices (AEMPS) and reviewed their summaries of product characteristics to determine their pediatric indications. We analyzed variables related to the authorization, commercialization, funding, and clinical characteristics of the drugs.</div></div><div><h3>Results</h3><div>We identified a total of 67 orphan drugs with pediatric indications authorized in Spain, which amounted to 50% of all orphan drugs. Of these, 22.4% were only indicated for pediatric use. Forty-nine (73.1%) were marketed and 46 were funded by the Spanish national health system, with restrictions in 63% of the funded cases.</div></div><div><h3>Conclusions</h3><div>Orphan drugs with pediatric indications remain a minority among orphan drugs. Pediatric clinical research needs to be reinforced, and strategies implemented to ensure more agile, equitable, and coordinated access. This study provides an updated overview based on official regulatory sources, although it did not allow the assessment of aspects such as access times or regional variability.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504315"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148922247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonate with gingival tumor","authors":"Alicia Utrera Ramos,&nbsp;Raquel Sánchez Jiménez,&nbsp;María del Mar Martín Latorre,&nbsp;Maria Idoia Serrano Saez de Argandoña","doi":"10.1016/j.anpede.2026.504224","DOIUrl":"10.1016/j.anpede.2026.504224","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504224"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148946189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful one-bag infliximab desensitization protocol in a 4-year-old patient with refractory arthritis","authors":"María José Peñalver,&nbsp;Celine Galleani,&nbsp;Ruth Barranco,&nbsp;Jesús F. Crespo","doi":"10.1016/j.anpede.2026.504297","DOIUrl":"10.1016/j.anpede.2026.504297","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"105 3","pages":"Article 504297"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148439544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}