Anales de pediatria最新文献

{"title":"Congenital syphilis on the rise. Review of a five-year period in a referral hospital in Portugal","authors":"Sara Catarino , Lídia Carvalho , Angélica Ramos , Manuela Rodrigues , Ana Reis-Melo","doi":"10.1016/j.anpede.2025.503800","DOIUrl":"10.1016/j.anpede.2025.503800","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503800"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herpes-zoster en un paciente vacunado recientemente de varicela","authors":"Omar Al-wattar-Ceballos, Marina Montero-García, Mónica Gómez-Manzanares, Carlos Mendoza-Chaparro","doi":"10.1016/j.anpede.2025.503723","DOIUrl":"10.1016/j.anpede.2025.503723","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503723"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The paradox of MBD, we know how to treat it but we don’t know how to diagnose it","authors":"Clara Chover Martínez, María Portolés Morales, Pilar Sáenz González, Álvaro Solaz García","doi":"10.1016/j.anpede.2025.503801","DOIUrl":"10.1016/j.anpede.2025.503801","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503801"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement of intestinal inflammation after treatment with CFTR modulators in cystic fibrosis patients","authors":"Ruth García Romero ,&nbsp;Concepción López Cárdenes ,&nbsp;Elena Crehuá Gaudiza ,&nbsp;Marina Álvarez Beltrán ,&nbsp;Mercedes Murray Hurtado ,&nbsp;Carlos Tutau Gómez ,&nbsp;Inés Loverdos Eseverri ,&nbsp;Encarni Torcuato Rubio ,&nbsp;Camila García Volpe ,&nbsp;Enrique Salcedo Lobato ,&nbsp;María Medina Martínez ,&nbsp;Carmen Martin Fernández ,&nbsp;Ana Moreno Álvarez ,&nbsp;Ana Reyes Domínguez ,&nbsp;David González Jiménez","doi":"10.1016/j.anpede.2025.503836","DOIUrl":"10.1016/j.anpede.2025.503836","url":null,"abstract":"<div><h3>Introduction</h3><div>Treatments with CFTR protein modulators have improved respiratory and digestive health in patients with cystic fibrosis.</div></div><div><h3>Objective</h3><div>To assess changes in intestinal inflammation through the analysis of fecal calprotectin in patients with cystic fibrosis during treatment with CFTR modulators.</div></div><div><h3>Material and methods</h3><div>Prospective multicenter study of changes in fecal calprotectin in patients with cystic fibrosis treated with CFTR modulators, comparing double combinations (lumacaftor/ivacaftor or tezacaftor/ivacaftor) and triple combinations (elexacaftor/tezacaftor/ivacaftor). We collected aata before treatment initiation and at 6 and 12 months.</div></div><div><h3>Results</h3><div>Analysis of 117 patients (69% with F508del/F508del). The median baseline fecal calprotectin level was 49 µg/g (IQR, 23–108); 48.7% had median levels greater than 50 µg/g and 11% levels greater than 250 µg/g. Fecal calprotectin decreased in both groups, with a greater decrease in patients treated with elexacaftor/tezacaftor/ivacaftor. We found a progressive decrease in abnormal values (&gt;50 µg/g) at 6 months (48.7% vs 33.1%; <em>P</em> = .0067) and at 12 months (54% vs 33.5%; <em>P</em> = .0218). In the elexacaftor/tezacaftor/ivacaftor group, only two patients at 6 months and one patient at 12 months had levels greater than 250 µg/g. The estimated change at 12 months in the triple therapy group compared to the other group was −133 µg/g (95% CI, −254 to −13; <em>P</em> = .030); and, adjusting for sex, probiotics and <em>Pseudomonas aeruginosa</em>, −130 µg/g (−259 to −1; <em>P</em> = .049).</div></div><div><h3>Conclusions</h3><div>Treatment with CFTR modulators reduces intestinal inflammation in patients with cystic fibrosis, with a greater decrease in patients treated with triple therapy.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503836"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144107744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital lung malformations: Do preoperative symptoms have an impact in surgical outcomes?","authors":"María López-Díaz ,&nbsp;Ester Fernández Díez ,&nbsp;Indalecio Cano Novillo ,&nbsp;Elena Bergón ,&nbsp;Rocío Morante Valverde ,&nbsp;Alberto Galindo Izquierdo ,&nbsp;Juan L. Antón-Pacheco","doi":"10.1016/j.anpede.2025.503835","DOIUrl":"10.1016/j.anpede.2025.503835","url":null,"abstract":"<div><h3>Introduction</h3><div>The management of congenital lung malformations (CLMs) is controversial because most of them are asymptomatic. The aim of our study was to analyze the association of preoperative symptoms with surgical outcomes in patients with CLMs treated by means of minimally invasive surgery (MIS).</div></div><div><h3>Patients and methods</h3><div>Retrospective study of patients with CLM treated with MIS in our hospital between 2003 and 2023. We recorded data on the following variables: demographic characteristics, size, type and location of the lesion, mediastinal shift, clinical symptoms, surgical time, conversion to open surgery, duration of chest drainage (days), length of stay and postoperative complications.</div></div><div><h3>Results</h3><div>The sample included 116 patients, 98 (84.4%) asymptomatic and 18 (15.5%) with clinically significant symptom: infectious in 10 (55.5%) and respiratory distress in eight. The most frequent histopathological type was congenital pulmonary airway malformation (35.5%), followed by intralobar sequestration (27.3%), and the lower lobes were most commonly involved (78.4%). Larger lesion size on the CT scan was significantly associated with the development of symptoms (<em>P</em> = .027) and with an increased frequency of conversion to open surgery. However, the incidence of postoperative complications was not greater in the symptomatic group.</div></div><div><h3>Conclusions</h3><div>Postoperative complications were not significantly more frequent in the symptomatic group of patients. Larger lesion size on imaging was associated with a significantly increased probability of developing symptoms, so these patients may benefit from early surgical resection.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503835"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyorchidism: A rare ultrasound finding","authors":"Maria Font Roset ,&nbsp;Isabel Sánchez Bueno ,&nbsp;Anton Foguet Vidal ,&nbsp;Stephan Otto Schneider","doi":"10.1016/j.anpede.2025.503769","DOIUrl":"10.1016/j.anpede.2025.503769","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503769"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of patients with a positive pulse oximetry screening depending on the time of screening","authors":"Elena Granda ,&nbsp;Silvia Pérez-Porra ,&nbsp;Silvia Martín-Ramos ,&nbsp;Sara Marín-Urueña ,&nbsp;Sonia Caserío-Carbonero","doi":"10.1016/j.anpede.2025.503799","DOIUrl":"10.1016/j.anpede.2025.503799","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503799"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior ankle impingement syndrome","authors":"Oihane Salcedo Fresneda ,&nbsp;Estibaliz Garrido García","doi":"10.1016/j.anpede.2025.503722","DOIUrl":"10.1016/j.anpede.2025.503722","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503722"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phleboliths as a radiological marker of venous malformation","authors":"Israel Pérez-López,&nbsp;Marta Cebolla-Verdugo,&nbsp;Ricardo Ruiz-Villaverde","doi":"10.1016/j.anpede.2025.503748","DOIUrl":"10.1016/j.anpede.2025.503748","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503748"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommendations for the management of functional dyspepsia from the SEGHNP working group on motility and functional gastrointestinal disorders","authors":"Miguel Ángel Carro Rodríguez ,&nbsp;Inmaculada Hidalgo Montes ,&nbsp;Carmen Jovani Casano ,&nbsp;Aránzazu Recio Linares ,&nbsp;Etna Masip Simó ,&nbsp;Gloria Rodrigo Garcia ,&nbsp;Andrés Bodas Pinedo ,&nbsp;en representación del Grupo de Trabajo de Motilidad y Trastornos Gastrointestinales funcionales de la SEGHNP","doi":"10.1016/j.anpede.2025.503860","DOIUrl":"10.1016/j.anpede.2025.503860","url":null,"abstract":"<div><h3>Introduction</h3><div>Functional dyspepsia (FD) is a functional gastrointestinal disorder that affects a significant number of patients, especially adolescents. Diagnosis is often challenging on account of both the differential diagnosis with organic diseases and the overlap with other disorders involving the gut-brain axis. Furthermore, there is a lack of scientific evidence on the effectiveness of the different treatments. As a result, there is evidence of substantial heterogeneity in the management of these patients due, in part, to the absence of clinical practice guidelines on this disease.</div></div><div><h3>Material and methods</h3><div>A group was formed that consisted of 19 members of the working group on motility and functional gastrointestinal disorders (FGIDS) of the SEGHNP. The group defined 27 clinical questions regarding the management of FD. After a review of the literature and two rounds of anonymous voting, the group elaborated a document summarizing the current evidence and offering recommendations.</div></div><div><h3>Results</h3><div>The group produced a summary of the evidence and developed 27 recommendations on FD.</div></div><div><h3>Conclusion</h3><div>We developed an algorithm with the aim of standardizing the management of patients with FD.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503860"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}