Acta cirurgica brasileira最新文献_第3页

Intravenous meropenem and intraperitoneal use of 10% aqueous extract of Schinus terebinthifolius Raddi (Anacardiaceae) in elderly rats after induction of autogenous fecal peritonitis. 老年大鼠自体排便性腹膜炎后静脉注射美罗培南，并腹腔注射10%山楂水提物。

Acta cirurgica brasileira Pub Date : 2025-01-13 eCollection Date: 2025-01-01 DOI: 10.1590/acb400325

Carlos Alberto Figueiredo Filho, Celia Maria Machado Barbosa de Castro, Guilherme Veras Mascena, Gustavo Ithamar Souto Maior, Tharcia Kiara Beserra Oliveira, Carlos Teixeira Brandt

{"title":"Intravenous meropenem and intraperitoneal use of 10% aqueous extract of Schinus terebinthifolius Raddi (Anacardiaceae) in elderly rats after induction of autogenous fecal peritonitis.","authors":"Carlos Alberto Figueiredo Filho, Celia Maria Machado Barbosa de Castro, Guilherme Veras Mascena, Gustavo Ithamar Souto Maior, Tharcia Kiara Beserra Oliveira, Carlos Teixeira Brandt","doi":"10.1590/acb400325","DOIUrl":"10.1590/acb400325","url":null,"abstract":"Purpose: To evaluate intravenous meropenem and intraperitoneal 10% aqueous extract of Schinus terebinthifolius (aroeira) in elderly rats after autogenous fecal peritonitis.Methods: Thirty 18-month-old Wistar rats underwent peritonitis with 4 mL/kg of autogenous fecal solution. They were stratified into groups: control without treatment; study I, treated with meropenem (40 mg/kg); and study II, treated with meropenem at the same dose and intraperitoneal 10% aqueous extract of aroeira. The animals were monitored for 15 days until euthanasia. The study was approved by Ethics Committee.Results: There was no significant weight loss in the study-II group (p = 0.6277), while the study-I group showed partially recovered weight (p = 0.0187). The study-II group had 90% negative blood cultures, while the study-I group had in 50% of the animals (p = 0.1479). Survival in the study-II group was higher than in study-I group (p = 0.0462). The morbidity score for abdominal and thoracic cavity was lower in the study-II group as compared with study-I group (p = 0.0001).Conclusions: The use of meropenem associated with the intraperitoneal 10% aqueous aroeira extract after induction of autogenous fecal peritonitis in elderly rats produced greater survival, less weight loss, and lower morbidity compared to the use of meropenem alone.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"40 ","pages":"e400325"},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling degenerative bone changes in the condyle: a texture analysis approach using cone-beam computed tomography. 揭示髁突退行性骨变化：使用锥形束计算机断层扫描的纹理分析方法。

Acta cirurgica brasileira Pub Date : 2025-01-13 eCollection Date: 2025-01-01 DOI: 10.1590/acb401325

Michelle Bianchi-de Moraes, Natália Caroline Queiroz Costa, Gabriella Yasmim Santos da Silva, Fernanda Calvo Costa, Fernando Vagner Raldi, Sérgio Lúcio Pereira de Castro Lopes

{"title":"Unveiling degenerative bone changes in the condyle: a texture analysis approach using cone-beam computed tomography.","authors":"Michelle Bianchi-de Moraes, Natália Caroline Queiroz Costa, Gabriella Yasmim Santos da Silva, Fernanda Calvo Costa, Fernando Vagner Raldi, Sérgio Lúcio Pereira de Castro Lopes","doi":"10.1590/acb401325","DOIUrl":"10.1590/acb401325","url":null,"abstract":"Purpose: The degenerative joint disease is a temporomandibular disorder. By analysing texture parameters, it becomes possible to characterize and differentiate various tissues, based on their textural properties according to cone-beam computed tomography (CBCT). This study evaluated degenerative diseases in the temporomandibular joint through texture analysis.Methods: Eighty images of the jaw condyle with three types of degenerative diseases, flattening, osteophytes, erosion and control group were analysed, obtained through CBCT. The analyses were carried out through texture analysis with three regions of interest (ROIs) corresponding to specific bone sites. The scans were exported to MaZda software, in which the ROIs were delimited following previously marked contours, and the co-occurrence matrix values were calculated for selected texture analysis parameters.Results: The erosion group showed a significantly different behaviour from the other groups for all analysed parameters.Conclusion: This study highlights the potential of texture analysis in characterizing medullary bone changes in condyles affected by erosion. Texture analysis allows for a more comprehensive assessment of bone condition on CBCT images. These results have implications for early detection and monitoring of degenerative changes in the temporomandibular joint, thus allowing preventive intervention and personalized treatment planning, improving the prognosis of the disease.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"40 ","pages":"e401325"},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive importance of cartilage acetabular index for acetabular dysplasia in orthopedic surgery. 骨科手术中髋臼软骨指数对髋臼发育不良的预测意义。

Acta cirurgica brasileira Pub Date : 2025-01-13 eCollection Date: 2025-01-01 DOI: 10.1590/acb400625

Mehmet Onur Ziyadanoğulları, Hüseyin Arslan

引用次数: 0

Effect of multiorgan abdominal ischemic preconditioning on experimental kidney transplantation. 多器官腹腔缺血预处理对实验性肾移植的影响。

Acta cirurgica brasileira Pub Date : 2024-12-20 eCollection Date: 2024-01-01 DOI: 10.1590/acb400225

Juan Cruz Abate, Ivana Ivanoff Marinoff, Nathalie Arnal, Mariana Machuca, Rodrigo Papa-Gobbi, Leandro Vecchio, Martín Rumbo, Pablo Stringa, Natalia Raquel Lausada

{"title":"Effect of multiorgan abdominal ischemic preconditioning on experimental kidney transplantation.","authors":"Juan Cruz Abate, Ivana Ivanoff Marinoff, Nathalie Arnal, Mariana Machuca, Rodrigo Papa-Gobbi, Leandro Vecchio, Martín Rumbo, Pablo Stringa, Natalia Raquel Lausada","doi":"10.1590/acb400225","DOIUrl":"https://doi.org/10.1590/acb400225","url":null,"abstract":"Purpose: To mitigate ischemia-reperfusion injury (IRI) triggered in solid organ transplant procedures, we aimed to evaluate the effects of multi-organ abdominal ischemic preconditioning (MAIP) in the context of renal IRI.Methods: An experimental kidney transplant model was conducted. Rats were divided into three groups: an intervention free basal group from which physiological data was collected; a control group (CT), which consisted of transplanted animals without MAIP; and a treated group, in which a MAIP protocol was implemented in the donor during the procurement of the left kidney, monitoring the recipient for 24 hours.Results: Urea, creatinine, and lactate dehydrogenase, as well as histopathological analysis (Banff: CT 1,66 ± 0,57 vs. basal 0, and MAIP 1), showed a clear trend in favor of MAIP group. Similar results were observed for tumor necrosis factor-α, interleukin-6 and CXCL10, as well as indicators of oxidative stress, with statistically significant levels for CXCL10 [0,295 ± 0,0074 arbitrary units (AU) CT and 0,0057 ± 0,0065 AU MAIP] and TBARS (2,93 ± 0,08 nmol/μg CT; and 2,49 ± 0,23 nmol/μg MAIP; p 0.05).Conclusion: The findings indicated that the MAIP exerts a protective influence on the transplanted kidneys, functioning as an IRI-protective strategy and enhancing the parameters associated with renal graft functionality.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"40 ","pages":"e400225"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peritoneal histopathological changes and cultures after autogenous fecal peritonitis induced in elderly rat model: response to intravenous use of meropenem and intra-abdominal inoculation of 10% aqueous extract of Schinus Terebinthifolius Raddi (Anacardiaceae). 老年大鼠自体性粪便性腹膜炎后腹膜组织病理学改变及培养：静脉注射美罗培南和腹腔内接种10%蛇尾水提物的反应。

Acta cirurgica brasileira Pub Date : 2024-12-20 eCollection Date: 2024-01-01 DOI: 10.1590/acb400125

Carlos Alberto Figueiredo Filho, Celia Maria Machado Barbosa Castro, Guilherme Veras Mascena, Gustavo Ithamar Souto Maior, Tharcia Kiara Beserra Oliveira, Valéria Wanderley Pinto Brandão Marquis, Carlos Teixeira Brandt

{"title":"Peritoneal histopathological changes and cultures after autogenous fecal peritonitis induced in elderly rat model: response to intravenous use of meropenem and intra-abdominal inoculation of 10% aqueous extract of Schinus Terebinthifolius Raddi (Anacardiaceae).","authors":"Carlos Alberto Figueiredo Filho, Celia Maria Machado Barbosa Castro, Guilherme Veras Mascena, Gustavo Ithamar Souto Maior, Tharcia Kiara Beserra Oliveira, Valéria Wanderley Pinto Brandão Marquis, Carlos Teixeira Brandt","doi":"10.1590/acb400125","DOIUrl":"https://doi.org/10.1590/acb400125","url":null,"abstract":"Purpose: To evaluate the peritoneal histopathological changes and culture after the use of intravenous meropenem and intra-abdominal inoculation of 10% aqueous extract of anacardiaceae, in elderly rat model after autogenous fecal peritonitis induced.Methods: Thirty 18-month-old Wistar rats received induction of autogenous fecal peritonitis and then were stratified into two groups: study I, treated with meropenem (40 mg/kg); and study II, treated with meropenem (40 mg/kg) and intraperitoneal 10% aqueous extract of anacardiaceae. Animals were monitored for 15 days until euthanasia. Peritoneal fragments were collected for histopathological and culture. The study was approved by Ethics Committee.Results: None study-II animals died, while in study I, one died before euthanasia. In study II, 20% of the animals showed histopathological changes, none positive peritoneal culture, but one blood culture was positive (10%). In study I, 50% of the animals presented histopathological changes, 40% positive peritoneal cultures, and 50% positive blood cultures. All results when evaluated in the morbidity score showed better outcome for study-II group (p = 0,175).Conclusion: The use of meropenem associated with intraperitoneal 10% aqueous anacardiaceae extract after induction of autogenous fecal peritonitis in elderly rats showed better outcome in the set of histopathological changes, negative peritoneal and blood cultures, when compared with the use of meropenem isolated.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"40 ","pages":"e400125"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and safety of remimazolam besylate and ciprofol in painless gastrointestinal endoscopy in the elderly. 苯磺酸雷马唑仑和环丙酚在老年人无痛胃肠内镜检查中的疗效和安全性。

Acta cirurgica brasileira Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.1590/acb399324

Ziwei Zhu

{"title":"Efficacy and safety of remimazolam besylate and ciprofol in painless gastrointestinal endoscopy in the elderly.","authors":"Ziwei Zhu","doi":"10.1590/acb399324","DOIUrl":"10.1590/acb399324","url":null,"abstract":"Purpose: This study aimed to ascertain the efficacy and safety of remimazolam besylate and ciprofol in elderly patients undergoing painless gastrointestinal endoscopy.Methods: Patients in the control group (n = 31) were anesthetized with ciprofol, and those in the observation group (n = 31) were anesthetized with remimazolam besylate. The anesthetic effect, analgesic effect, hemodynamics, cognitive function, and adverse reactions between the two groups were compared.Results: The observation group had shorter anesthesia onset time, recovery time, as well as anesthesia recovery room stay time and a higher effective rate of analgesia. At T1, T2, and T3, the mean arterial pressure and heart rate of the observation group were higher versus the control group; at T1 and T2, SpO2 in the observation group was higher versus the control group. The simple mental state scale score of the observation group was higher than that of the control group (all p 0.05). The total incidence of adverse reactions exhibited no difference between the two groups (p> 0.05).Conclusion: Versus ciprofol, remimazolam besylate has better anesthetic and analgesic effects, more stable hemodynamics, less impact on patients' cognitive function, and good safety in elderly patients undergoing painless gastrointestinal endoscopy.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"39 ","pages":"e399324"},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacological effects of triamcinolone associated with surgical glue on cutaneous wound healing in rats. 曲安奈德联合手术胶对大鼠皮肤创面愈合的药理作用。

Acta cirurgica brasileira Pub Date : 2024-12-06 eCollection Date: 2024-01-01 DOI: 10.1590/acb399624

Rosana Soares Araújo Doci, Filipe Feitosa de Carvalho, Rodrigo César Gomes, Reinaldo José Gianini, Camilla Fanelli, Irene de Lourdes Noronha, Nelson Brancaccio Dos Santos, Moema de Alencar Hausen, Daniel Komatsu, Priscila Randazzo-Moura

{"title":"Pharmacological effects of triamcinolone associated with surgical glue on cutaneous wound healing in rats.","authors":"Rosana Soares Araújo Doci, Filipe Feitosa de Carvalho, Rodrigo César Gomes, Reinaldo José Gianini, Camilla Fanelli, Irene de Lourdes Noronha, Nelson Brancaccio Dos Santos, Moema de Alencar Hausen, Daniel Komatsu, Priscila Randazzo-Moura","doi":"10.1590/acb399624","DOIUrl":"10.1590/acb399624","url":null,"abstract":"Purpose: The surgical glue is widely used in closing cutaneous surgical wounds. Corticosteroids are indicated for their anti-inflammatory and immunomodulatory properties. The present work evaluated the pharmacological effects of triamcinolone (AT) incorporated into surgical glue (C) on the initial phase of the wound healing process in Wistar rats.Methods: Through in-vivo studies, the effects of the healing process, C or C+AT in the same rat were evaluated for seven and 14 days post-surgery.Results: The C+AT association did not change the physicochemical properties of the polymer. This association in wound healing confirmed the anti-inflammatory and immunomodulatory effects of the corticosteroid, with less neovascularization and fibrosis, in addition to the remodeling of the extracellular matrix carried out by the balance of myofibroblasts and less dense collagen fibers, culminating in tissue regeneration and possible reduction of side effects.Conclusion: This association is a powerful and innovative pharmacological tool, promising in translational medicine.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"39 ","pages":"e399624"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the therapeutic effects of different pneumoperitoneum pressures on laparoscopic transabdominal preperitoneal hernia repair: a randomized controlled trail. 不同气腹压力在腹腔镜经腹腹膜前疝修补术中的疗效比较：随机对照试验。

Acta cirurgica brasileira Pub Date : 2024-12-06 eCollection Date: 2024-01-01 DOI: 10.1590/acb399824

Jie Yao, Shichen Qin, Guang Yang

{"title":"Comparison of the therapeutic effects of different pneumoperitoneum pressures on laparoscopic transabdominal preperitoneal hernia repair: a randomized controlled trail.","authors":"Jie Yao, Shichen Qin, Guang Yang","doi":"10.1590/acb399824","DOIUrl":"10.1590/acb399824","url":null,"abstract":"Purpose: To compare the indicators, postoperative pneumoretroperitoneum-related complications, and postoperative recovery of laparoscopic preperitoneal inguinal hernia repair under different CO2 pneumoperitoneum pressures.Methods: The total of 187 adult patients with primary inguinal hernia who successfully underwent transabdominal preperitoneal prosthesis (TAPP) from September 2021 to September 2023 in the Department of General Surgery, Haimen People's Hospital affiliated to Nantong University, were collected. These patients were randomly divided into low abdominal pressure group (group A: pneumoperitoneum pressure = 8 mmHg), sub-low abdominal pressure group (group B: pneumoperitoneum pressure = 10 mmHg), moderate abdominal pressure group (group C: pneumoperitoneum pressure = 12 mmHg), and standard pressure group (group D: pneumoperitoneum pressure = 14 mmHg), with 40 patients each.Results: The operation time in group C (43.90 ± 9.75) was significantly lower than group A (51.98 ± 12.65, p 0.001), group B (46.70 ± 10.59, p 0.001), and was higher than that in group D without significant statistical differences (38.15 ± 7.98, P = 0.05). The peritoneal suturing time in group C (5.03 ± 1.07) was significantly higher than group A (4.23 ± 0.70, p 0.001), group B (4.55 ± 0.85, p = 0.03), and was significantly lower than that in group D (6.95 ± 1.96, p 0.001).Conclusion: Selecting sub-low abdominal pressure (12 mmHg) can help to have a shorter operation time, with less blood loss, and it did not add pneumoretroperitoneum-related complications. Changing the pneumoperitonium pressure during different phases of the surgery is also an optimal option.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"39 ","pages":"e399824"},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calendula glycolic extract enhances wound healing of alginate hydrogel. 金盏花乙醇酸提取物促进伤口愈合海藻酸盐水凝胶。

Acta cirurgica brasileira Pub Date : 2024-11-29 eCollection Date: 2024-01-01 DOI: 10.1590/acb399724

Gisele de Oliveira Krubniki Possa, Solange Chopek, Airton Vicente Pereira, Adriana Yuriko Koga, Marcia Regina Paes de Oliveira, Michele Dietrich Moura Costa

{"title":"Calendula glycolic extract enhances wound healing of alginate hydrogel.","authors":"Gisele de Oliveira Krubniki Possa, Solange Chopek, Airton Vicente Pereira, Adriana Yuriko Koga, Marcia Regina Paes de Oliveira, Michele Dietrich Moura Costa","doi":"10.1590/acb399724","DOIUrl":"10.1590/acb399724","url":null,"abstract":"Purpose: To assess the cytotoxicity and wound healing properties of an alginate hydrogel containing calendula glycolic extract.Methods: Cell viability in murine fibroblasts (3T3 cells) was evaluated using MTT and SRB assays. The wound healing effect was tested in an incisional wound model on 50 female Wistar rats, divided into two groups: rats treated with alginate hydrogel (n = 25), and rats treated with calendula-alginate hydrogel. Wound healing was assessed by measuring wound retraction rate and histological analysis of lesion tissues over a 28-day period. Histological analyses were performed on days 2, 7, 14, 21, and 28 post-surgery to examine inflammatory infiltrate, macrophage count, and angiogenesis. Picrosirius red staining was used to compare the relative abundance of collagen types I and III fibers.Results: Cytotoxicity tests on 3T3 cells revealed increased cell viability with the calendula-alginate hydrogel. The calendula-alginate hydrogel also demonstrated a significant improvement in wound closure, supported by histopathological analysis, showing reduced inflammation, increased macrophage activity, and enhanced collagen deposition.Conclusions: These findings evidenced the therapeutic potential of combining calendula extract and alginate for promoting enhanced wound healing.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"39 ","pages":"e399724"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical, thermographic, and tensiometric evaluation of rat cutaneous wounds treated with collagen gel associated with F18 bioactive glass. F18生物活性玻璃相关胶原凝胶处理大鼠皮肤伤口的临床、热成像和张力评估。

Acta cirurgica brasileira Pub Date : 2024-11-29 eCollection Date: 2024-01-01 DOI: 10.1590/acb399424

Bruna Martins da Silva, Ivan Felismino Charas Dos Santos, Paula Mancuso, Letícia Albuquerque Fortes Pereira, Ivan Moroz, Marina Frazatti Gallina, Miriam Harumi Tsunemi, Marina Trevelin Souza, Claudia Helena Pellizzon, José Ivaldo Siqueira Silva Júnior, Cláudia Valéria Seullner Brandão, Liandra Amara Garcia Alves

{"title":"Clinical, thermographic, and tensiometric evaluation of rat cutaneous wounds treated with collagen gel associated with F18 bioactive glass.","authors":"Bruna Martins da Silva, Ivan Felismino Charas Dos Santos, Paula Mancuso, Letícia Albuquerque Fortes Pereira, Ivan Moroz, Marina Frazatti Gallina, Miriam Harumi Tsunemi, Marina Trevelin Souza, Claudia Helena Pellizzon, José Ivaldo Siqueira Silva Júnior, Cláudia Valéria Seullner Brandão, Liandra Amara Garcia Alves","doi":"10.1590/acb399424","DOIUrl":"10.1590/acb399424","url":null,"abstract":"Purpose: To evaluate the association of collagen gel with F18 bioactive glass (BG) in the healing of non-contaminated cutaneous wounds induced in healthy Wistar rats.Methods: One hundred twelve adult and healthy Wistar rats were randomly divided into four groups (n = 28): saline solution (0.9%); healing ointment based on allantoin and zinc oxide; collagen gel; and association of F18 BG powder and collagen gel. All the rats underwent the creation of a 3-cm diameter wound in their dorsal region. Macroscopic, thermographic, and tensiometric evaluations of the wound were performed.Results: The presence of granulation tissue varied significantly in and between the groups. The surface temperature assessed through thermography of wounds treated with saline solution (0.9%) increased significantly over time and between the groups. No difference was identified regarding tensiometry.Conclusions: Collagen gel associated with F18 BG induced beneficial healing effects on non-contaminated cutaneous wounds in Wistar rats, which included the induction of increased blood perfusion as assessed through thermography.","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"39 ","pages":"e399424"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0