Willane Bandeira de Sousa, João Nogueira Neto, Kauã Manuel Costa Araújo, Lyvia Maria Rodrigues de Sousa Gomes, Maria do Socorro de Sousa Cartagenes, João Batista Santos Garcia
{"title":"Induced and spontaneous uterine leiomyomas in animal models: a scoping review.","authors":"Willane Bandeira de Sousa, João Nogueira Neto, Kauã Manuel Costa Araújo, Lyvia Maria Rodrigues de Sousa Gomes, Maria do Socorro de Sousa Cartagenes, João Batista Santos Garcia","doi":"10.1590/acb414426","DOIUrl":"10.1590/acb414426","url":null,"abstract":"<p><strong>Purpose: </strong>To map the experimental models of induced and spontaneous uterine leiomyomas (UL) in animals, describing induction techniques, evaluation methods, advantages, limitations, and research gaps.</p><p><strong>Methods: </strong>We conducted a systematic review of studies published between 2004 and 2024 with in-vivo animal experiments reporting UL induction or spontaneous occurrence. Data were extracted on animal species, sample size, induction methods, confirmation techniques, and reported advantages or disadvantages.</p><p><strong>Results: </strong>A total of 56 studies were included. Rats and mice were the most frequently used species. Induction methods comprised hormonal administration, genetic predisposition, chemical exposure (monosodium glutamate), ischemic injury, external stimulation, cell transplantation, xenotransplantation, and spontaneous development. A critical finding that emerged was that 60.7% of the studies failed to report confirmation of UL induction. Among the 22 studies that reported confirmation, caliper measurement was the most frequently used technique. This widespread lack of methodological rigor significantly undermines the credibility and reproducibility of many published models.</p><p><strong>Conclusion: </strong>This scoping review highlights not only the heterogeneity of UL animal models and the lack of standardized induction and evaluation protocols, but also identifies a critical gap in induction validation reporting that compromises the foundation of preclinical research in this field.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e414426"},"PeriodicalIF":1.3,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13432877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148686979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eren Altun, Duygu Lafci, Ceyda Sancakli Usta, Mustafa Hilmi Yaranoglu, Eray Metin Guler
{"title":"The impact of enoxaparin on ovarian torsion-detorsion damage in rats.","authors":"Eren Altun, Duygu Lafci, Ceyda Sancakli Usta, Mustafa Hilmi Yaranoglu, Eray Metin Guler","doi":"10.1590/acb414526","DOIUrl":"10.1590/acb414526","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the protective effects of enoxaparin on ovarian tissue subjected to experimental ischemia/reperfusion (I/R) injury in rats.</p><p><strong>Methods: </strong>Thirty female rats were divided into three groups: control, ischemia/reperfusion (I/R), and ischemia/reperfusion plus enoxaparin (I/R+E). Ovarian I/R injury was induced by 1 hour of ischemia followed by 1 hour of reperfusion. Rats in the I/R+E group received subcutaneous enoxaparin (0.5 mg/kg) prior to ischemia. Histopathological injury was assessed using a standardized scoring system, and total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were measured.</p><p><strong>Results: </strong>Histopathological injury scores were significantly higher in the I/R group compared with controls (p < 0.05), with no significant difference between the I/R and I/R+E groups (p > 0.05). Biochemical analysis showed significantly higher TAS and lower OSI levels in the I/R+E group compared with the I/R group (p < 0.05), while TOS levels were comparable between groups.</p><p><strong>Conclusion: </strong>Although enoxaparin did not significantly improve histopathological injury, its beneficial effects on oxidative stress parameters suggest a protective role against oxidative stress in ovarian I/R injury.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e414526"},"PeriodicalIF":1.3,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13432874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148686969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Edmundo Rodrigues Fontes, Rafael Fernandez Castilio, Félix Plaza Moreno, Mateus de Amorim Aboboreira, Maria Luíza Bernardo de Lima, Yves Henrique Ramos Mansano, Claudio Bodgan, Willian Cesar Cavazana, Miyoko Massago, Sanderland José Tavares Gurgel, Luciano de Andrade
{"title":"Augmented reality in clinical skills simulation: usability and feasibility of smart glasses in a simulated environment.","authors":"Carlos Edmundo Rodrigues Fontes, Rafael Fernandez Castilio, Félix Plaza Moreno, Mateus de Amorim Aboboreira, Maria Luíza Bernardo de Lima, Yves Henrique Ramos Mansano, Claudio Bodgan, Willian Cesar Cavazana, Miyoko Massago, Sanderland José Tavares Gurgel, Luciano de Andrade","doi":"10.1590/acb414626","DOIUrl":"10.1590/acb414626","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the usability and feasibility of augmented-reality smart glasses during simulated pediatric bladder catheterization with real-time remote specialist guidance.</p><p><strong>Methods: </strong>Thirty-five critical-care graduate healthcare professionals simulated pediatric bladder catheterization on a manikin using Vuzix M400 glasses via telemedicine. After brief familiarization, participants completed a seven-item Likert (0-7) questionnaire covering ease of use, procedural understanding, confidence/efficiency, comfort, and global acceptance. We analyzed descriptive statistics, internal consistency (Cronbach's α), and item-domain coherence. A conceptual diagram and synthesis table complemented quantitative data.</p><p><strong>Results: </strong>Augmented-reality-guided training showed generally favorable usability perceptions. Median scores ranged 3.5-5, with strongest ratings for observation support, image quality, procedural understanding, and intention to recommend. Comfort and efficiency scored lower (median = 3.5), indicating more neutral perceptions. The instrument showed high internal consistency (α = 0.97), although this may reflect item redundancy, and item-domain alignment provided a descriptive representation of the conceptual model.</p><p><strong>Conclusion: </strong>These findings suggest that augmented-reality smart glasses are feasible and generally well accepted for simulated remotely guided training. Further controlled studies with objective performance measures are needed.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e414626"},"PeriodicalIF":1.3,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13432875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148686850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcos Fraga Fortes, Gabriela Noronha Fortes, Marcos Noronha Fortes, Fernanda Christoffel Gomes, Marilia Seelaendar, Ariene Murari Soares de Pinho, Joyce de Cassia Rosa de Jesus, José Pinhata Otoch
{"title":"Lower content of cerebrospinal fluid chemokines in patients with cancer cachexia.","authors":"Marcos Fraga Fortes, Gabriela Noronha Fortes, Marcos Noronha Fortes, Fernanda Christoffel Gomes, Marilia Seelaendar, Ariene Murari Soares de Pinho, Joyce de Cassia Rosa de Jesus, José Pinhata Otoch","doi":"10.1590/acb414726","DOIUrl":"10.1590/acb414726","url":null,"abstract":"<p><strong>Purpose: </strong>Cancer-associated cachexia (CC) is characterized by involuntary weight loss and poor prognosis. Central nervous system (CNS) inflammation has been linked to CC symptoms. This study evaluated inflammatory mediators in the cerebrospinal fluid (CSF) of patients with CC.</p><p><strong>Methods: </strong>Volunteers were recruited in Santarém, PA, Brazil, and divided into three groups: patients undergoing herniorrhaphy or cholecystectomy (n = 43)-control; cancer without cachexia (CWC, n = 13); and CC (n = 49). Blood and CSF were collected before anesthetic injection.</p><p><strong>Results: </strong>CSF vascular endothelial growth factor (VEGF) and monocyte chemoattractant protein-1 (MCP-1) levels were reduced in CC (p < 0.0001; p 0.00017) and CWC (p = 0.0269; p = 0.0421) compared to control. CSF IP-10 was lower in CC (p = 0.0048). In CWC, CSF MCP-1 correlated with serum C reactive protein (rs = 0.78, p = 0.0098), leukocytes (rs = 0.72, p = 0.0235), lymphocytes (rs = -0.67, p = 0.0390) and monocytes (rs = -0.82, p = 0.0058). In CC, CSF interleukin (IL)-8 correlated with leukocytes (rs = 0.48, p = 0.0032) and MCP-1 with neutrophils (rs = 0.36, p = 0.0265) and eosinophils (rs = -0.37, p = 0.0218). CC patients showed lower quality of life than CWC (functional scale p = 0.0087; symptoms scale p = 0.0386).</p><p><strong>Conclusion: </strong>Cancer was related to changes in CSF cytokine levels, indicating that both tumor presence and cachexia modulate central inflammatory signaling. Correlations between CSF chemokines and blood immune cells suggest systemic interaction between peripheral immunity and the CNS.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e414726"},"PeriodicalIF":1.3,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13432878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148687017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A novel combined neutrophil-platelet score for diagnosing complicated appendicitis: a retrospective and prospective cohort study.","authors":"Xiang Li, Jiangshun Yang, Dengyang Fang, Wei Dai, Zuming Xiong, Xuan Chen","doi":"10.1590/acb413926","DOIUrl":"10.1590/acb413926","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) and combined them to create an inflammatory marker, the combined neutrophil-platelet score (CNPS), to serve as a diagnostic and predictive tool for complicated appendicitis.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinicopathological data of patients who underwent appendectomy. Receiver operating characteristic (ROC) curves and the area under the curve (AUC) were used to evaluate the diagnostic performance of various inflammatory parameters. Univariate and multivariate logistic regression analyses were performed to identify independent risk factors for complicated appendicitis. A prospective study was then carried out to validate the clinical utility of the CNPS.</p><p><strong>Results: </strong>In total, 322 patients were included in the retrospective analysis. Multivariate analysis identified only onset time and NLR as independent risk factors for complicated appendicitis, whereas the PLR was not. CNPS demonstrated superior diagnostic and predictive performance for complicated appendicitis compared to NLR and PLR. Moreover, after adjusting for confounders, CNPS remained an independent risk factor for complicated appendicitis. In the prospective study, 264 patients were included for analysis, and the AUC of CNPS for predicting complicated appendicitis was 0.707.</p><p><strong>Conclusion: </strong>The CNPS, combining NLR and PLR, demonstrates high diagnostic and predictive value for complicated appendicitis.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e413926"},"PeriodicalIF":1.3,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148623040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brenda Feres, Sarah Lopes Salomão, Luiza Telles, Paulo Henrique Melo, Lauren Kratky, Jaqueline Dourado, Esther Louise Freire Costa, David Patrick Mooney, Gabriel Schnitman
{"title":"Trauma care in Brazil: a comparative study of patient characteristics at public versus private hospitals.","authors":"Brenda Feres, Sarah Lopes Salomão, Luiza Telles, Paulo Henrique Melo, Lauren Kratky, Jaqueline Dourado, Esther Louise Freire Costa, David Patrick Mooney, Gabriel Schnitman","doi":"10.1590/acb414026","DOIUrl":"10.1590/acb414026","url":null,"abstract":"<p><strong>Purpose: </strong>Trauma remains a leading cause of hospital admissions worldwide, particularly in low- and middle-income countries. Brazil's dual healthcare system reflects disparities in resource availability and clinical outcomes. This study compared epidemiological profiles of trauma patients treated at a public versus a private hospital in Salvador, Bahia, Brazil.</p><p><strong>Methods: </strong>We retrospectively analyzed 6,472 trauma-related hospitalizations from August 2021 to August 2023. Data were extracted from Hospital Information System/Department of Informatics of the Unified Health System and a private hospital database. Patients admitted under the 10th revision of the International Classification of Diseases, categories S00-T88, were included, excluding burns and orthopedic injuries. A χ2 test assessed associations between trauma mechanisms and hospitals.</p><p><strong>Results: </strong>Among the 6,472 cases, 6,342 occurred in the public hospital and 130 in the private hospital. In the public hospital, males accounted for 82.1% of the cases, and the leading causes were motorcycle crashes (21.7%) and gunshot wounds (16.2%). At the private hospital 58.4% of patients were males, with falls (50.8%) predominating among older adults. Violence-related injuries predominated in the public hospital, while falls predominated in the private hospital.</p><p><strong>Conclusion: </strong>This study revealed distinct trauma patterns in the public versus the private hospital in one Brazilian city. The public hospital treated younger male victims of violence, while the private hospital treated older patients with falls. These findings underscore the need for policies addressing trauma care disparities.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e414026"},"PeriodicalIF":1.3,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13399392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kenan Sabuncu, Mehmet Ali Sezgin, Emre Can Polat, Erkan Merder, Alper Ötünçtemur, Mustafa Baki Çekmen, Saniye Koç Ada, Cem Çomunoğlu, Levent Özcan
{"title":"Time-dependent protective effects of syringic acid following testicular torsion-detorsion: an experimental rat model.","authors":"Kenan Sabuncu, Mehmet Ali Sezgin, Emre Can Polat, Erkan Merder, Alper Ötünçtemur, Mustafa Baki Çekmen, Saniye Koç Ada, Cem Çomunoğlu, Levent Özcan","doi":"10.1590/acb414226","DOIUrl":"10.1590/acb414226","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the protective effects of syringic acid (SA) against testicular ischemia-reperfusion (I/R) injury during different reperfusion periods in an experimental rat model.</p><p><strong>Methods: </strong>Forty-eight male Wistar albino rats were randomly assigned to six groups: control, sham, torsion/detorsion (T/D) 4 h, T/D + SA 4 h, T/D 24 h, and T/D + SA 24 h. Testicular torsion was induced by 720° rotation of the left testis for 2 h, followed by detorsion and 4 or 24 h reperfusion. SA (10 mg/kg) was administered intraperitoneally 30 min before detorsion. Oxidative stress markers, histopathological alterations, and immunohistochemical expressions of apoptotic protease activating factor-1 (APAF-1) and inducible nitric oxide synthase were evaluated.</p><p><strong>Results: </strong>T/D significantly decreased total antioxidant status and glutathione levels while increasing myeloperoxidase activity and APAF-1/inducible nitric oxide synthase (iNOS) expressions compared with controls (p < 0.001). SA treatment restored antioxidant capacity and attenuated inflammatory and apoptotic responses (p < 0.05). Histopathological analyses demonstrated lower Cosentino scores and higher Johnsen scores in SA-treated groups than in untreated T/D groups (p < 0.05). Malondialdehyde levels showed no significant intergroup differences.</p><p><strong>Conclusion: </strong>SA attenuates testicular I/R injury by reducing oxidative stress, inflammation, and apoptosis while preserving spermatogenic function and histological integrity.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e414226"},"PeriodicalIF":1.3,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148623001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diego Armando Leite Carvalho, Gustavo Sousa Marques, Yanna Ribeiro Macêdo, Igor Iuco Castro-Silva
{"title":"Biocompatibility, biodegradation, and antioxidative potential of alginate-dragon's blood sap microbeads implanted subcutaneously in mice.","authors":"Diego Armando Leite Carvalho, Gustavo Sousa Marques, Yanna Ribeiro Macêdo, Igor Iuco Castro-Silva","doi":"10.1590/acb414126","DOIUrl":"10.1590/acb414126","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate alginate-dragon's blood sap microbeads (DBSM) regarding biocompatibility, biodegradation, and antioxidative potential.</p><p><strong>Methods: </strong>Three DBSMs at concentrations of 1, 2, and 5% were developed by the drop spherification, and alginate-1% glycerin microbeads (GM) were used as control. Biocompatibility and biodegradation were evaluated by subcutaneous assay in 50 Swiss male mice, divided in the groups G1 (1% DBSM), G2 (2% DBSM) and G3 (5% DBSM), which were compared to C+ (1% GM) and C- (sham) at three and nine weeks. The histopathology of tissue irritation followed the ISO 10993-6 standard and the integrity of the biomaterials scored by quartiles. Metabolic analysis of intensity of catalase was carried out in the liver, kidneys, and tibias of the tested animals.</p><p><strong>Results: </strong>All microbeads were biocompatible, with less tissue irritation and greater partial resorption in G3 in subcutaneous tissue and preserved systemic antioxidant potential.</p><p><strong>Conclusion: </strong>The controlled release of dragon's blood sap from Croton lechleri using alginate microbeads suggests a local anti-inflammatory action dependent on the concentration of the bioactive compound. Its role in repairing specialized connective tissues such as bone should be elucidated by future in-vivo orthotopic tests.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e414126"},"PeriodicalIF":1.3,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148623048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anatomical study of the innervation of the tibialis anterior muscle and its relationship with myofascial trigger points.","authors":"Jéssica Bevilaqua Congio, César Rocha de Alencar, Flávio Carneiro Hojaij, Mauro Figueiredo Carvalho de Andrade, Alfredo Luiz Jacomo, Flávia Emi Akamatsu","doi":"10.1590/acb414326","DOIUrl":"10.1590/acb414326","url":null,"abstract":"<p><strong>Purpose: </strong>Myofascial trigger points (MTPs) in the tibialis anterior muscle (TAM) are located in the upper third of the muscle and can be activated by various pathologies such as sprains, fractures, and muscle overload. Although the pathophysiology of MTPs is unclear, they often coincide with motor plates in the innervation zone. This study aimed to describe the innervation of the deep fibular nerve (DFN) into the TAM and relate it to clinically described MTPs.</p><p><strong>Methods: </strong>The TAMs of 12 cadavers were dissected from their origins to observe the exact point at which the DFN penetrates the muscle belly. Entry points were mapped by dividing the muscle into four areas. Statistical analysis was performed using a Poisson marginal distribution and identity linkage function, followed by Bonferroni multiple comparisons. Statistical analysis included summary measures, group comparisons using Student and Mann-Whitney's tests, and Pearson and Spearman's correlations. Statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>Quadrants I and II had significantly more DFN branches than quadrants III and IV (p < 0.001), whereas quadrants I versus II and areas III versus IV showed no significant differences (p < 0.05).</p><p><strong>Conclusion: </strong>Consistent with the clinical literature, the branches of the DFN in the TAM correspond to the described areas of the MTPs. The anatomical relationships between MTPs may help explain the pathophysiology of various disorders and provide rational treatment options.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e414326"},"PeriodicalIF":1.3,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148623014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bruno Tavares de Andrade, Carlo Átila Holanda Lopes, Yury Tavares de Lima, Victor Rocha Pincanço, Natan Rolim de Assunção Bisio, Henrique Luis do Carmo E Sa, Josué Viana de Castro Neto
{"title":"Development and preliminary evaluation of a camera-assisted endovascular simulator using a three-dimensional printing.","authors":"Bruno Tavares de Andrade, Carlo Átila Holanda Lopes, Yury Tavares de Lima, Victor Rocha Pincanço, Natan Rolim de Assunção Bisio, Henrique Luis do Carmo E Sa, Josué Viana de Castro Neto","doi":"10.1590/acb413826","DOIUrl":"10.1590/acb413826","url":null,"abstract":"<p><strong>Purpose: </strong>This study described the development and preliminary evaluation of a simulator that combines a three-dimensional-printed vascular model with a camera-assisted system for training basic endovascular skills.</p><p><strong>Methods: </strong>A hollow mannequin torso housed a transparent, three-dimensional-printed aorta. Guidewire and catheter manipulation were visualized in real time using a manually controlled camera. Fifteen medical students (novices) and five vascular surgeons (experts) performed simulated tasks in two sessions. Experts also assessed realism and educational value.</p><p><strong>Results: </strong>Novices demonstrated shorter completion times across all exercises in session 2, particularly in exercise 4, with mean time decreasing from 229.3 ± 134.8 to 83.5 ± 31.1 seconds, a mean difference of 145.8 seconds (p = 0.001). Experts showed no significant improvement in most tasks, although exercise 3 improved from 115.4 ± 29.7 to 91.6 ± 21.5 seconds, a mean difference of 23.8 seconds (p = 0.012). Performance differed between groups (construct validity). Surgeons provided favorable ratings for the realism and usefulness (face and content validity).</p><p><strong>Conclusion: </strong>This preliminary device appears feasible and may facilitate early skill acquisition in low-resource educational settings without radiation exposure.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e413826"},"PeriodicalIF":1.3,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148551730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}