British Journal of Radiology最新文献

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Calculating optic nerve planning organ at risk volume margins for stereotactic radiosurgery using optic nerve motion determined using MRI: Response to Letter. 利用MRI确定视神经运动来计算立体定向放射手术中视神经规划器官的危险体积边缘。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-10-01 DOI: 10.1093/bjr/tqaf073
Sagar Sabharwal, Geoff Heyes, George S J Tudor, Robert Flintham, Swarupsinh Chavda, Paul Sanghera
{"title":"Calculating optic nerve planning organ at risk volume margins for stereotactic radiosurgery using optic nerve motion determined using MRI: Response to Letter.","authors":"Sagar Sabharwal, Geoff Heyes, George S J Tudor, Robert Flintham, Swarupsinh Chavda, Paul Sanghera","doi":"10.1093/bjr/tqaf073","DOIUrl":"10.1093/bjr/tqaf073","url":null,"abstract":"","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"1720"},"PeriodicalIF":3.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Agentic AI in radiology: emerging potential and unresolved challenges. 放射学中的人工智能:新兴潜力和未解决的挑战。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-10-01 DOI: 10.1093/bjr/tqaf173
Nicholas Dietrich
{"title":"Agentic AI in radiology: emerging potential and unresolved challenges.","authors":"Nicholas Dietrich","doi":"10.1093/bjr/tqaf173","DOIUrl":"10.1093/bjr/tqaf173","url":null,"abstract":"<p><p>This commentary introduces agentic artificial intelligence (AI) as an emerging paradigm in radiology, marking a shift from passive, user-triggered tools to systems capable of autonomous workflow management, task planning, and clinical decision support. Agentic AI models may dynamically prioritize imaging studies, tailor recommendations based on patient history and scan context, and automate administrative follow-up tasks, offering potential gains in efficiency, triage accuracy, and cognitive support. While not yet widely implemented, early pilot studies and proof-of-concept applications highlight promising utility across high-volume and high-acuity settings. Key barriers, including limited clinical validation, evolving regulatory frameworks, and integration challenges, must be addressed to ensure safe, scalable deployment. Agentic AI represents a forward-looking evolution in radiology that warrants careful development and clinician-guided implementation.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"1582-1584"},"PeriodicalIF":3.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12515039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144706410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging and endovascular interventions in renal arteriovenous shunts. 肾动静脉分流术的影像学和血管内干预。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-10-01 DOI: 10.1093/bjr/tqaf154
Divij Agarwal, Sanchita Gupta, Chandan J Das, Pradeep Hatimota, Sai Krishna Gadwal
{"title":"Imaging and endovascular interventions in renal arteriovenous shunts.","authors":"Divij Agarwal, Sanchita Gupta, Chandan J Das, Pradeep Hatimota, Sai Krishna Gadwal","doi":"10.1093/bjr/tqaf154","DOIUrl":"10.1093/bjr/tqaf154","url":null,"abstract":"<p><p>Renal arteriovenous shunts are rare vascular anomalies that develop due to aberrant communication between the renal arteries and veins, bypassing intervening capillaries. They can be broadly classified into arteriovenous malformations (usually congenital) and, more commonly, arteriovenous fistula (usually acquired). When symptomatic, they can lead to the development of hematuria, high-output cardiac failure, hypertension, renal impairment, or retroperitoneal hematoma. Imaging techniques, such as Doppler ultrasound, Digital subtraction angiography, computed tomography angiography, and MR angiography, can help accurately identify and categorize these renal arteriovenous shunts. While open surgery was once the standard of care, endovascular embolization has gained popularity due to its efficacy and minimally invasive nature. Embolization of these lesions is tailored to the type, severity, and flow dynamics of the shunt. Detailed imaging assessment and meticulous preprocedural planning are critical for optimal management, including preservation of residual renal function. This article describes the causes, classification, imaging findings and endovascular management of renal arteriovenous shunts.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"1556-1572"},"PeriodicalIF":3.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the reliability of outcome measures in rheumatology juvenile idiopathic arthritis MRI scoring system for sacroiliac joint. 风湿病预后指标可靠性评估(OMERACT)青少年特发性关节炎骶髂关节磁共振成像评分系统(JAMRIS SIJ)。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-10-01 DOI: 10.1093/bjr/tqaf189
Dilek Sağlam, Hasan Emin Kaya, Başak Erdemli Gürsel, Kübra Zora, Bartu Barlas, Gökhan Gökalp, İlker Ercan, Sara Şebnem Kılıç, Zeynep Yazıcı
{"title":"Assessment of the reliability of outcome measures in rheumatology juvenile idiopathic arthritis MRI scoring system for sacroiliac joint.","authors":"Dilek Sağlam, Hasan Emin Kaya, Başak Erdemli Gürsel, Kübra Zora, Bartu Barlas, Gökhan Gökalp, İlker Ercan, Sara Şebnem Kılıç, Zeynep Yazıcı","doi":"10.1093/bjr/tqaf189","DOIUrl":"10.1093/bjr/tqaf189","url":null,"abstract":"<p><strong>Objectives: </strong>Outcome measures in Rheumatology (OMERACT) Juvenile Idiopathic Arthritis MRI Score in the sacroiliac joint (JAMRIS-SIJ) have been developed by the Rheumatoid Arthritis Study Group for the need for a standardized evaluation of SIJ in children. This study aims to evaluate the interrater reliability (IRR) of JAMRIS SIJ.</p><p><strong>Methods: </strong>Patients younger than 18 years with a diagnosis of enthesitis-related arthritis and who had a sacroiliac MRI scan between October 2014 and December 2023 were enrolled in the study. Demographic data of the patients were recorded from clinical charts. Five raters examined the MRI scans and JAMRIS SIJ scores were recorded. IRR was assessed with intraclass correlation coefficient (ICC).</p><p><strong>Results: </strong>The study comprised 40 MRI examinations of 31 patients. Fifteen of 31 patients were female. The median age at referral for scanning was 14.4 years. The ICC was 0.870 (0.780-0.935) (P < .001) and 0.654(0.473-0.791) (P < .001); for the inflammation and structural damage domains, respectively. Bone marrow edema had the highest IRR (ICC = 0.910 [0.863-0.946]; P < .001) from all components evaluated in JAMRIS-SIJ, and fat lesion had the highest IRR (ICC = 0.764 [0.648-0.855]; P < .001) from structural damage components.</p><p><strong>Conclusions: </strong>Our results indicate that JAMRIS SIJ is reliable in evaluating most inflammation and structural damage components. JAMRIS SIJ may be used as a quantitative guide for the therapeutic management of patients with JIA.</p><p><strong>Advances in knowledge: </strong>JAMRIS-SIJ is a reliable tool for evaluating inflammatory and structural damage components of sacroiliitis.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"1713-1717"},"PeriodicalIF":3.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-world performance evaluation of commercial autocontouring software for head and neck cancer radiotherapy. 商用头颈癌放疗自动轮廓软件的实际性能评价。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-10-01 DOI: 10.1093/bjr/tqaf098
Tom Young, Victoria Butterworth, Sarah Misson, Delali Adjogatse, Anthony Kong, Imran Petkar, Miguel Reis Ferreira, Mary Lei, Andrew King, Teresa Guerrero Urbano
{"title":"Real-world performance evaluation of commercial autocontouring software for head and neck cancer radiotherapy.","authors":"Tom Young, Victoria Butterworth, Sarah Misson, Delali Adjogatse, Anthony Kong, Imran Petkar, Miguel Reis Ferreira, Mary Lei, Andrew King, Teresa Guerrero Urbano","doi":"10.1093/bjr/tqaf098","DOIUrl":"10.1093/bjr/tqaf098","url":null,"abstract":"<p><strong>Objectives: </strong>To comprehensively evaluate the ability of ART-Plan (autocontouring software using artificial intelligence [AI]) to contour head and neck cancer (HNC) radiotherapy structures (organs-at-risk and elective nodal volumes) in a real-world setting, as required by NICE guidelines.</p><p><strong>Methods: </strong>Retrospective evaluation (n = 60) compared clinically used contours to AI-contours, using volumetric dice similarity coefficient (VDSC) and blinded radiation oncologist (RO) contour preference assessment. AI-contours were then generated prospectively for HNC radiotherapy patients (n = 61), before review by ROs. ROs recorded qualitative scoring and review/editing time. Geometric and dosimetric comparison of AI-contours and final contours was undertaken. Correlation coefficients between all metrics were calculated.</p><p><strong>Results: </strong>Retrospective median VDSC varied widely for different structures (0.23-0.88). 31.4% blinded contour assessments preferred clinician-generated contours, 32.9% preferred AI-generated contours, 35.7% saw no significant difference. Prospective evaluation showed AI-contour yielded significant time-saving in reviewing/editing for all structures compared to manual contouring. Qualitative scores demonstrated most structures had median scoring ≥4 (indicating no editing required). Geometric metrics showed high similarity for all structures except larynx. Dosimetric evaluation demonstrated clinically significant dose differences for larynx and elective nodal volumes. Strong correlation was seen between qualitative scoring and all geometric metrics.</p><p><strong>Conclusions: </strong>AI-contours showed excellent qualitative performance and facilitated time-saving. Protocol differences exist between commercial AI-solutions and implementing centres. Ongoing final clinician review of AI-contours remains essential.</p><p><strong>Advances in knowledge: </strong>This is the first study demonstrating ART-Plan's capability for excellent qualitative ratings and significant time-savings for HNC radiotherapy contouring in a real-world workflow setting. 5-point Likert-scale qualitative scoring correlates strongly with geometric metrics.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"1632-1641"},"PeriodicalIF":3.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12515040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter arterial embolization with N-butyl-2 cyanoacrylate or not for iatrogenic renal haemorrhage under normal coagulation condition. 正常凝血条件下医源性肾出血是否应用氰基丙烯酸丁酯经导管栓塞。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-10-01 DOI: 10.1093/bjr/tqaf170
Yuan Wan, Yang Liu, Dan Li, Tao Peng, Ke-Tong Wu, Bo Zhang
{"title":"Transcatheter arterial embolization with N-butyl-2 cyanoacrylate or not for iatrogenic renal haemorrhage under normal coagulation condition.","authors":"Yuan Wan, Yang Liu, Dan Li, Tao Peng, Ke-Tong Wu, Bo Zhang","doi":"10.1093/bjr/tqaf170","DOIUrl":"10.1093/bjr/tqaf170","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effectiveness and safety of transcatheter arterial embolization (TAE) with N-butyl-2 cyanoacrylate (NBCA) versus without NBCA for the treatment of iatrogenic renal haemorrhage (IRH) in patients with normal coagulation profiles.</p><p><strong>Methods: </strong>Forty-nine participants with normal coagulation profiles were divided into 2 groups: NBCA (n = 12) and non-NBCA (n = 37). The primary outcome assessed was the primary clinical success rate, with secondary analyses conducted on technical success rate, secondary clinical success rate, procedure duration and cost, angiographic results, and adverse events.</p><p><strong>Results: </strong>Patients exhibited a near-normal coagulation condition (98.4%, 50/51). Technical success was attained in all patients, with no statistically significant differences observed between primary clinical success rate (P > .99), secondary clinical success rate (P > .99), procedure time (P = .469), and surgical costs (P  = .057) when comparing the sides. In the non-NBCA group, negative angiographic findings were more prevalent compared with the NBCA group (43.2% vs 0, P = .012). No significant differences were found in serum creatinine and urea levels before and after treatment in both the groups (P > .05). Minor complications were observed after the TAE procedure, with a higher percentage in the NBCA group compared with the non-NBCA group (P = .088).</p><p><strong>Conclusions: </strong>TAE has been shown to be a safe and effective treatment for IRH in patients with normal coagulation conditions, regardless of the use of NBCA glue.</p><p><strong>Advances in knowledge: </strong>There were no significant differences in procedure time or costs between the NBCA group and other treatment modalities. However, these findings require validation in large-scale randomized controlled trials.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"1664-1670"},"PeriodicalIF":3.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic yield of multiple X-ray imaging requests of lower limb extremities. 下肢多种x线影像要求的诊断率。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-10-01 DOI: 10.1093/bjr/tqaf183
Dania Abu Awwad, Don Nocum, Ernest Ekpo
{"title":"Diagnostic yield of multiple X-ray imaging requests of lower limb extremities.","authors":"Dania Abu Awwad, Don Nocum, Ernest Ekpo","doi":"10.1093/bjr/tqaf183","DOIUrl":"10.1093/bjr/tqaf183","url":null,"abstract":"<p><strong>Objectives: </strong>The diagnosis pathway for patients presenting in the emergency department with lower limb trauma injuries requires adequate medical imaging of the regions of interest. Due to concerns of concurrent injury or overlapping symptoms, X-rays of multiple lower extremity regions may be requested simultaneously. This article explores the diagnostic yield of imaging multiple lower limb regions following trauma.</p><p><strong>Methods: </strong>A retrospective audit of lower limb imaging requests for patients older than 18 years from 2 hospitals was conducted. Region requested, clinical history, and radiology findings for initial and secondary requests for adjacent body parts within 24 hours were collected and analysed using χ2 analysis.</p><p><strong>Results: </strong>There were a total of 1473 examinations with 646 patients. Initial X-rays were significantly more likely to diagnose new, suspicious, and other findings compared to secondary X-rays of adjacent regions (χ2(3) = 377.504, P < .001). Overall, 12.4% (n = 183/1473) of X-rays detected abnormalities such as fractures, and 160 of these 183 abnormalities (87.4%) were detected on the initial X-ray with the remaining 23 abnormalities (12.6%) detected in secondary X-rays. Only 0.9% (n = 6/646) of patients had a concurrent injury.</p><p><strong>Conclusion: </strong>X-ray imaging of multiple lower extremities adjacent to injured areas has low diagnostic yield. Thorough clinical assessment is needed to reduce low-value imaging in lower limb trauma.</p><p><strong>Advances in knowledge: </strong>Concurrent injury in lower limbs injuries is rare. When multiple X-ray requests are made of adjacent regions, 87.4% of all abnormalities were detected on initial imaging. The diagnostic yield of secondary X-rays is very low particularly when patients are asymptomatic.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"1677-1682"},"PeriodicalIF":3.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12515038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unlocking the Potential of Training: Enhancing Inter-reader Agreement in Background Parenchymal Enhancement Assessment. 释放训练的潜力:增强背景实质增强评估的读者间协议。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-09-30 DOI: 10.1093/bjr/tqaf240
Danping Huang, Sina Wang, Zhendong Luo, Lijun Chen, Hui Zeng, Fengxia Zeng, Jialing Liu, Weimin Xu, Genggeng Qin
{"title":"Unlocking the Potential of Training: Enhancing Inter-reader Agreement in Background Parenchymal Enhancement Assessment.","authors":"Danping Huang, Sina Wang, Zhendong Luo, Lijun Chen, Hui Zeng, Fengxia Zeng, Jialing Liu, Weimin Xu, Genggeng Qin","doi":"10.1093/bjr/tqaf240","DOIUrl":"https://doi.org/10.1093/bjr/tqaf240","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the inter-reader agreement of visual background parenchymal enhancement (BPE) assessment and determine if training can improve this assessment.</p><p><strong>Methods: </strong>Five hundred and forty-eight women who underwent contrast-enhanced mammography from 2018 through 2022 were included. A total of 2135 images were read by six radiologists (Group A) independently and rated BPE with the ordinal scale: minimal, mild, moderate, or marked. After a dedicated training, the same cases were reread in a new random order within two weeks. To further verify the effectiveness of training, four radiologists (Group B) from four different institutions were invited to assess BPE in the same way with 800 images. The accuracy of each reader and agreement on BPE categorization between radiologists and the reference standard were evaluated.</p><p><strong>Results: </strong>The percentage of correct BPE assignments increased from 62.3% (range, 48.6%-73.6%) to 75.5% (range, 69.0%-79.7%) after training in Group A, and increased from 55.7% (range, 52.0%-58.9%) to 66.9% (range, 62.0%-71.0%) after training in Group B. With training, inter-reader agreement increased from fair to moderate in both Group A (κ  =  0.32 to 0.52) and Group B (κ  =  0.40 to 0.53), indicating readers learned and the training can be rolled out to different institutions.</p><p><strong>Conclusion: </strong>The initial inter-reader agreement in assessing BPE among radiologists was fair but showed enhancement following training, highlighting the necessity of training and standard sets of reference images that should be made available for training.</p><p><strong>Advances in knowledge: </strong>This study demonstrates that dedicated training improves inter-reader agreement in BPE assessment on CEM, highlighting the need for standardized training programs to enhance consistency in clinical practice and research.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The additional role of contrast-enhanced ultrasound in identifying lesions in pathological nipple discharge patients: a prospective study comparing with DCE-MRI. 对比增强超声在鉴别病理性乳头溢液患者病变中的额外作用:一项与DCE-MRI比较的前瞻性研究。
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-09-30 DOI: 10.1093/bjr/tqaf244
Qinghua Niu, Shiyun Yang, Lianfang Du, Chao Jia, Gang Li, Yingyu Cai, An Chen, Fan Li
{"title":"The additional role of contrast-enhanced ultrasound in identifying lesions in pathological nipple discharge patients: a prospective study comparing with DCE-MRI.","authors":"Qinghua Niu, Shiyun Yang, Lianfang Du, Chao Jia, Gang Li, Yingyu Cai, An Chen, Fan Li","doi":"10.1093/bjr/tqaf244","DOIUrl":"https://doi.org/10.1093/bjr/tqaf244","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the auxiliary role of contrast-enhanced ultrasound (CEUS) in the etiological diagnosis of pathological nipple discharge (PND) and compare its effectiveness with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).</p><p><strong>Methods: </strong>In this prospective study conducted from March 2021 to February 2024, PND patients underwent breast ultrasound and DCE-MRI after initial history and physical examination. Lesions were categorized as mass or non-mass-like on baseline US and assessed for vascularity using color Doppler. CEUS was utilized to refine the breast imaging reporting and data system (BI-RADS) classification. Logistic regression identified risk factors, and diagnostic performance was evaluated using receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>A total of 116 lesions from 112 PND patients were analyzed. CEUS-assisted ultrasound showed increased specificity (ranging from 50.0% to 80.0% compared to US alone, p = 0.009) while maintaining sensitivity. Of the 81 patients who underwent DCE-MRI, CEUS demonstrated a higher positive predictive value (83.3% vs. 75.5%), with comparable negative predictive values (97.0% vs. 96.4%). CEUS was particularly effective in accurately diagnosing benign lesions that were overestimated by DCE-MRI and in identifying ductal carcinoma in situ with greater precision than US alone.</p><p><strong>Conclusion: </strong>The auxiliary use of CEUS with ultrasound improves the specificity and positive predictive value in diagnosing PND-associated malignancies and serves as a valuable secondary imaging method to DCE-MRI, potentially reducing unnecessary biopsies of benign lesions.</p><p><strong>Advances in knowledge: </strong>CEUS can enhance the diagnostic accuracy of PND, effectively differentiating benign from malignant lesions, and its integration into clinical practice could offer significant benefits in patient management.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between left ventricular myocardial fibrosis and left atrial dysfunction in patients with non-obstructive hypertrophic cardiomyopathy. 非阻塞性肥厚性心肌病患者左室心肌纤维化与左房功能障碍的相关性
IF 3.4 4区 医学
British Journal of Radiology Pub Date : 2025-09-27 DOI: 10.1093/bjr/tqaf135
Yan Zheng, Xiaochun Zhang, Huairong Zhang, Liyuan Ma, Xiao Sun, Pei Wang, Li Zhu
{"title":"Correlation between left ventricular myocardial fibrosis and left atrial dysfunction in patients with non-obstructive hypertrophic cardiomyopathy.","authors":"Yan Zheng, Xiaochun Zhang, Huairong Zhang, Liyuan Ma, Xiao Sun, Pei Wang, Li Zhu","doi":"10.1093/bjr/tqaf135","DOIUrl":"https://doi.org/10.1093/bjr/tqaf135","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the impact of left ventricular myocardial fibrosis on left atrial function in patients with non-obstructive hypertrophic cardiomyopathy (NOHCM).</p><p><strong>Methods: </strong>A total of 103 NOHCM patients and 28 healthy controls (HC) were included retrospectively. Patients were stratified based on late gadolinium enhancement (LGE) into the following groups: NOHCM LGE (-) group, mild LGE% (+) group (LGE% < 7%), moderate LGE% (+) group (7% ≤ LGE% < 15%), and severe LGE% (+) group (LGE% ≥ 15%). CMR-FT strain analysis assessed left atrial strain and strain rate across different cardiac phases. Statistical analyses for clinical and imaging parameters, and Spearman correlation analysis for assessing correlations between left ventricular myocardial fibrosis and left atrial volume and function.</p><p><strong>Results: </strong>There were no significant differences in left atrial function and volume parameters between the LGE (-) group and the mild LGE% (+) group. However, εs, εe, SRs, and SRe showed gradual decreases across mild, moderate, and severe LGE% (+) groups, with significant differences observed among the three groups. εa and SRa in the moderate and severe LGE% (+) groups were significantly lower than those in the mild LGE% (+) group. There are strong correlations between the degree of left ventricular myocardial fibrosis and LAEF, LAEDV, LAESV, εs, εe, εa, SRs, SRe, and SRa.</p><p><strong>Conclusion: </strong>As left ventricular myocardial fibrosis progressed, left atrial function deteriorated further, highlighting an interaction between left ventricular myocardial structure and left atrial function that promotes NOHCM progression.</p><p><strong>Advances in knowledge: </strong>Complement the guidelines(2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy).</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145173627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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