Jin Joo Kim, Jin You Kim, Kyung Jin Nam, Kye Young Lee, Ki Seok Choo, Taewoo Kang, Heeseung Park, Seong Hwan Bae
{"title":"Multiparametric Magnetic Resonance Imaging Assessment of Primary Tumors for Predicting Axillary Tumor Burden in Women with Invasive Breast Cancer.","authors":"Jin Joo Kim, Jin You Kim, Kyung Jin Nam, Kye Young Lee, Ki Seok Choo, Taewoo Kang, Heeseung Park, Seong Hwan Bae","doi":"10.1093/bjr/tqae243","DOIUrl":"https://doi.org/10.1093/bjr/tqae243","url":null,"abstract":"<p><strong>Objective: </strong>To assess the association between multiparametric MRI features of primary tumors and axillary lymph node tumor burden in women with invasive breast cancer.</p><p><strong>Methods: </strong>In this retrospective study, women diagnosed with invasive breast cancer who underwent 3T multiparametric MRI, including diffusion-weighted imaging (DWI) from 2019-2020, were evaluated. Two radiologists reviewed T2-weighted images (T2WI) for peritumoral edema and intratumoral necrosis, and measured apparent diffusion coefficient (ADC) values by manually placing regions of interest within breast tumors. We also analyzed quantitative kinetic features of breast cancer using computer-aided diagnosis (CAD) and clinical-pathologic characteristics. Uni- and multivariable logistic regression analyses were conducted to identify predictors of a high axillary nodal burden (≥3 positive nodes).</p><p><strong>Results: </strong>In total, 301 women (mean age, 54.13 years) were evaluated. Forty-three (14.3%) had a high axillary nodal burden by surgical pathology. Multivariate analysis revealed that factors significantly associated with high axillary nodal burden included peritumoral edema (OR:7.970; p<0.001), lower tumor ADCmax (≤ 1.098 × 10-3 mm2/s) (OR:6.978; p<0.001), larger tumor size (>2cm) (OR:2.986; p=0.046), lobular histology (OR:12.620; p<0.001), and the presence of lymphovascular invasion (OR:3.622; p=0.003). CAD-derived kinetic features did not show an association with axillary nodal burden. In subgroup analysis of 238 patients with early clinically node-negative breast cancer, both peritumoral edema (OR:7.831; p=0.002) and lower tumor ADCmax (≤ 1.098 × 10-3 mm2/s) (OR:8.002; p=0.002) remained significant predictors.</p><p><strong>Conclusion: </strong>Our results suggest that peritumoral edema as viewed in T2WI and the ADCmax value of breast cancer in DWI are valuable for predicting axillary nodal burden in women with invasive breast cancer.</p><p><strong>Advances in knowledge: </strong>Multiparametric MRI features of a primary tumor are useful for predicting axillary nodal burden in patients with invasive breast cancer.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vimal Chacko, Dr Jayakrishana, Jineesh Valakkada, Anoop Ayappan, Santhosh Kannath, Deepa S Kumar, Arun Goplakrishana
{"title":"Imaging and endovascular management of haemoptysis in congenital heart disease.","authors":"Vimal Chacko, Dr Jayakrishana, Jineesh Valakkada, Anoop Ayappan, Santhosh Kannath, Deepa S Kumar, Arun Goplakrishana","doi":"10.1093/bjr/tqae239","DOIUrl":"https://doi.org/10.1093/bjr/tqae239","url":null,"abstract":"<p><p>Haemoptysis, a rare but serious complication that can arise in patients with congenital heart disease (CHD), necessitates prompt diagnosis and specialised care. The radiologist plays a critical role in this scenario, including identifying the source of haemoptysis, devising treatment plans, and delivering endovascular interventions. This article highlights the importance of imaging techniques, especially computed tomography (CT), in identifying the cause of haemoptysis and the therapeutic value of endovascular interventions. Furthermore, a suggested algorithmic approach is presented to assist with the diagnostic and management process.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reversible Electroporation for Cancer Therapy.","authors":"Taha Shiwani, Simran Dhesi, Tze Min Wah","doi":"10.1093/bjr/tqae231","DOIUrl":"https://doi.org/10.1093/bjr/tqae231","url":null,"abstract":"<p><p>Reversible electroporation refers to the use of high voltage electrical pulses on tissues to increase cell membrane permeability. It allows targeted delivery of high concentrations of chemotherapeutic agents including cisplatin and bleomycin, a process known as electrochemotherapy (ECT). It can also be used to deliver toxic concentrations of calcium and gene therapies that stimulate an anti-tumour immune response. ECT was validated for palliative treatment of cutaneous tumours. Evidence to date shows a mean objective response rate of ∼80% in these patients. Regression of non-treated lesions has also been demonstrated, theorised to be from an in-situ vaccination effect. Advances in electrode development have also allowed treatment of deep-seated metastatic lesions and primary tumours, with safety demonstrated in vivo. Calcium electroporation and combination immunotherapy or immunogene electrotransfer is also feasible, but research is limited. Adverse events of ECT are minimal; however, general anaesthesia is often necessary, and improvements in modelling capabilities and electrode design are required to enable sufficient electrical coverage. International collaboration between preclinical researchers, oncologists and interventionalists is required to identify the most effective combination therapies, to optimise procedural factors, and to expand use, indications and assessment of reversible electroporation. Registries with standardised data collection methods may facilitate this.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gadoxetic Acid-Enhanced MRI in Differentiating Focal Nodular Hyperplasia from Hepatocellular Adenoma in Children.","authors":"Başak Erdemli Gürsel, Gökhan Öngen, Selman Candan, Nadide Başak Gülleroğlu, Betül Berrin Sevinir, Zeynep Yazıcı","doi":"10.1093/bjr/tqae222","DOIUrl":"https://doi.org/10.1093/bjr/tqae222","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the diagnostic performance of Gd-EOB-enhanced magnetic resonance imaging (MRI) for distinguishing focal nodular hyperplasia (FNH) from hepatocellular adenoma (HCA) in children.</p><p><strong>Methods: </strong>Twenty-two patients (6 with HCA and 16 with FNH) were retrospectively included in this study. After qualitative analyses of MRI, quantitative analyses were performed by calculating the relative signal intensity ratios (SIR) between lesion and liver parenchyma both on precontrast and hepatobiliary phase images. Two equations, SIRpost-pre and liver-to-lesion contrast enhancement ratio (LLCER), using both SIRs of precontrast and hepatobiliary phase (HBP) imaging together were also calculated.</p><p><strong>Results: </strong>The most distinguishing non-contrast-enhanced MRI feature of HCA was intralesional fat since all HCA contained fat but none of FNHs. All FNHs were iso- or hyperintense relative to the adjacent liver on HBP images, but all HCAs except one were hypointense. The mean SIRpost-pre and LLCER of FNH were significantly higher than that of HCA (p < 0,001). SIRpost-pre and LLCER provided sensitivity and specificity values of 100%.</p><p><strong>Conclusion: </strong>Although intralesional fat is a strong discriminative feature for distinguishing between HCA and FNH, qualitative properties of these lesions may not be enough for confident diagnosis. Gd-EOB uptake in the HBP provides high diagnostic accuracy, but overlap can be seen. SIRpost-pre and LLCER overcome the difficulties and have the best sensitivity and specificity.</p><p><strong>Advances in knowledge: </strong>Although there are many similar studies in adult group, this is one of the rare studies that will contribute to the literature in the pediatric group.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adnan G Taib, Iain T H Au-Yong, Arjun Nair, Anand Devaraj, Yan Chen, David R Baldwin
{"title":"Quality assurance in lung cancer screening.","authors":"Adnan G Taib, Iain T H Au-Yong, Arjun Nair, Anand Devaraj, Yan Chen, David R Baldwin","doi":"10.1093/bjr/tqae229","DOIUrl":"https://doi.org/10.1093/bjr/tqae229","url":null,"abstract":"<p><p>The effectiveness of screening programmes is critically dependent on the accuracy of the screening test. Where this relies on clinical expertise, there is an imperative to assure that the level of expertise meets expected standards. In cancer screening involving images, the focus is on the reader. Auditing of results is fraught with difficulty because of the time taken to accumulate enough data with confirmed outcomes to identify underperformance before any harm is done. Late recognition can lead to the need for reanalysis and recall of screening participants with loss of confidence in the programme. External Quality Assurance (EQA) is a method that enables clinical expertise to be tested rapidly by using test datasets with confirmed clinical outcome. In the UK, the breast cancer screening programme has had EQA in place for over 30 years. This article describes the development of the first EQA process in lung cancer screening, using the experience gained from running the breast cancer EQA, and the proposed future developments.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The optimal energy level of virtual monochromatic imaging in Dual-energy CT arthrography of the wrist.","authors":"Bo Mi Chung, Guen Young Lee, Sujin Kim","doi":"10.1093/bjr/tqae238","DOIUrl":"https://doi.org/10.1093/bjr/tqae238","url":null,"abstract":"<p><strong>Objectives: </strong>To suggest an optimal energy level of virtual monochromatic images (VMIs) in dual-energy CT arthrography of the wrist.</p><p><strong>Methods: </strong>This retrospective study included 53 patients with wrist CT arthrography. Conventional polychromatic images and VMIs at four energy levels (40 to 70 keV at 10 keV intervals) were obtained. Image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were measured, and qualitative analysis of image quality and diagnostic confidence was performed. For each patient, an energy level with the best image quality was chosen by consensus. Comparisons of quantitative and qualitative parameters between VMI sets were performed.</p><p><strong>Results: </strong>The image noise of bone and muscle were increased with decreasing energy level (p < 0.001). The noise of contrast was highest on 60 keV VMI. SNR and CNR (between contrast and muscle) were increased with decreasing energy level and were markedly increased between 60 and 50 keV (p < 0.001). The 60 keV VMI demonstrated the highest image quality and diagnostic confidence, chosen as the best diagnostic image (n = 31/53). Given that the attenuation of the contrast material was low on the conventional image, the optimal energy level of the best VMI tended to be low.</p><p><strong>Conclusion: </strong>Wrist dual-energy CT arthrography with VMIs at 60 keV or less could improve image quality and diagnostic performance by increasing SNR and CNR in cases with low contrast attenuation.</p><p><strong>Advances in knowledge: </strong>Wrist dual-energy CT arthrography with VMIs at variable keV could be utilised to enhance SNR and CNR, thereby achieving diagnostic images of high quality.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DynaCT biliary reconstruction via a 3D C-arm cholangiography system: clinical application in hepatolithiasis.","authors":"Ya-Wen Cao, Dong-Qiao Chen, Jie-Long Lin, Zhao-Wei Ding, Pei-Heng Li, Rong-Qi Li, Yong-Qing Ye","doi":"10.1093/bjr/tqae237","DOIUrl":"https://doi.org/10.1093/bjr/tqae237","url":null,"abstract":"<p><strong>Objective: </strong>Dyna computed tomography (DynaCT) is an innovative clinical imaging tool used to obtain three-dimensional (3D) images of biliary structures via the Artis Zee DSA system (SIEMENS Company, Germany). DynaCT is a type of 3D cone beam computed tomography (CBCT) reconstruction produced from a two-dimensional (2D) cholangiography system by rotating the C-arm without moving the patient. The aim of this study was to evaluate the technical approach and application value of DynaCT to diagnosis hepatolithiasis and biliary stenosis.</p><p><strong>Methods: </strong>This was a retrospective single-centre series of 37 hepatolithiasis patients with tubes receiving one-step percutaneous transhepatic cholangioscopic lithotripsy (one-step PTCSL) between October 2021 and October 2022: twenty-one patients were guided by CT (CT group) and sixteen by DynaCT biliary reconstruction (DynaCT group). We compared DynaCT biliary reconstruction technology with computed tomography (CT) in the application of bile ducts.</p><p><strong>Results: </strong>DynaCT biliary reconstruction was successfully performed in 37 patients. Biliary stenosis, including anatomy, morphology, and size, was visualized via DynaCT. Compared with the CT group, the DynaCT group was characterized by significantly more target biliary branches with stones (92 vs. 48, P < 0.05), a higher percentage of secondary stenosis (75.76% vs. 24.24%, p < 0.05), a greater percentage of biliary infection (37.5% vs. 9.5%, P = 0.041), a shorter overall stone clearance time (26.38 ± 13.49 vs. 52.67 ± 30.10, P = 0.001), and a lower rate of reoperation for residual stones (25.00% vs. 66.67%, P = 0.012). DynaCT had a lower contrast agent (25.61 ± 5.13 vs. 42.69 ± 11.15, p < 0.05). However, DynaCT increased radiation exposure (38.12 ± 10.59 vs. 25.79 ± 4.76, p < 0.05). There were no significant differences between the two groups regarding the clearance ratio of the calculus or several postoperative complications.</p><p><strong>Conclusion: </strong>DynaCT for biliary reconstruction has the potential to be a powerful evaluation tool for one-step PTCSL surgery and could lead to new possibilities for hepatobiliary surgery.</p><p><strong>Advances in knowledge: </strong>DynaCT was used for the first time in patients with hepatolithiasis and biliary stenosis. Compared with CT, DynaCT for biliary reconstruction results in higher-quality 3D biliary, blood vessel and liver images. On the basis of the DynaCT biliary model, one-step PTCSL has the potential to improve the stone clearance ratio and shorten the stone clearance time and reoperation ratio.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142614797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review of Applications of Photon-Counting Computed Tomography in Head and Neck Imaging.","authors":"Siddhant Dogra, Nitesh Shekhrajka, Gul Moonis","doi":"10.1093/bjr/tqae226","DOIUrl":"https://doi.org/10.1093/bjr/tqae226","url":null,"abstract":"<p><p>Photon-counting CT (PCCT), approved for clinical practice for over two years now, both improves on features of conventional energy-integrating detector (EID) CT and introduces new capabilities such as multienergy acquisition. PCCT is already transforming all domains of radiology, including head and neck imaging, and will become increasingly utilized in the approaching years. In this review, we first concisely explain the key physical principles distinguishing PCCT from EID-CT. We then discuss how the underlying physics leads to the novel features associated with PCCT, focusing on improved artifact reduction, spatial resolution, contrast-to-noise ratio, as well as multienergy acquisition and reduced contrast and radiation doses. Next, we review head and neck PCCT applications and comparison to EID-CT in dental imaging, sinus imaging, temporal bone, tumor imaging, and vascular imaging. Within the temporal bone applications, we explore normal anatomy, pathologic anatomy, and the appearance of protheses and implants. Representative imaging is provided to highlight differences between PCCT and EID-CT. Finally, we highlight areas of ongoing research in PCCT.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142614399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li-Wen Du, Hong-Li Liu, Meng-Jun Cai, Jia-Zhen Pan, Hai-Ling Zha, Chen-Lei Nie, Min-Jia Lin, Cui-Ying Li, Min Zong, Bo Zhang
{"title":"Ultrasound S-detect system can improve diagnostic performance of less experienced radiologists in differentiating breast masses. A retrospective dual-center study.","authors":"Li-Wen Du, Hong-Li Liu, Meng-Jun Cai, Jia-Zhen Pan, Hai-Ling Zha, Chen-Lei Nie, Min-Jia Lin, Cui-Ying Li, Min Zong, Bo Zhang","doi":"10.1093/bjr/tqae233","DOIUrl":"https://doi.org/10.1093/bjr/tqae233","url":null,"abstract":"<p><strong>Objective: </strong>To compare the performance of radiologists when assisted by an S-detect system with that of radiologists or an S-detect system alone in diagnosing breast masses on US images in a dual-center setting.</p><p><strong>Methods: </strong>US images were retrospectively identified 296 breast masses (150 benign, 146 malignant) by investigators at two medical centers. Six radiologists from the two centers independently analyzed the US images and classified each mass into categories 2 to 5. The radiologists then re-reviewed the images with the assistance of the S-detect system. The diagnostic value of radiologists alone, S-detect system alone, and S-detect alone, and radiologists + S-detect were analyzed and compared.</p><p><strong>Results: </strong>Radiologists had significantly decreased the average false negative rate (FNR) for diagnosing breast masses using S-detect system (- 10.7%) (P < 0.001) and increased the area under the receiver operating characteristic curve (AUC) from 0.743 to 0.788 (P < 0.001). Seventy-seven out of 888 US images from six radiologists in this study were changed positively (from false negative to true positive or from false positive to true negative) with the S-detect, while 39 out of 888 US images were altered negatively.</p><p><strong>Conclusion: </strong>Radiologists had better performance for the diagnosis of malignant breast masses on US images with an S-detect system than without.</p><p><strong>Advances in knowledge: </strong>The study used a dual-center design and compared the performance of the radiologists alone, the S-detect alone, and the radiologists combined with the S-detect. The study reported an improvement in sensitivity and AUC particularly for low to intermediate-level radiologists, involved cases and radiologists from two different centers, and compared the diagnostic value of using S-detect system for masses of different sizes.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing the Performance of ChatGPT and Bard/Gemini Against Radiologists for PI-RADS Classification Based on Prostate Multiparametric MRI Text Reports.","authors":"Kang-Lung Lee, Dimitri A Kessler, Iztok Caglic, Yi-Hsin Kuo, Nadeem Shaida, Tristan Barrett","doi":"10.1093/bjr/tqae236","DOIUrl":"https://doi.org/10.1093/bjr/tqae236","url":null,"abstract":"<p><strong>Objectives: </strong>Large language models (LLMs) have shown potential for clinical applications. This study assesses their ability to assign PI-RADS categories based on clinical text reports.</p><p><strong>Methods: </strong>One hundred consecutive biopsy-naïve patients' multiparametric prostate MRI reports were independently classified by two uroradiologists, GPT-3.5, GPT-4, Bard, and Gemini. Original report classifications were considered definitive.</p><p><strong>Results: </strong>Out of 100 MRIs, 52 were originally reported as PI-RADS 1-2, 9 PI-RADS 3, 19 PI-RADS 4, and 20 PI-RADS 5. Radiologists demonstrated 95% and 90% accuracy, while GPT-3.5 and Bard both achieved 67%. Accuracy of the updated versions of LLMs increased to 83% (GTP-4) and 79% (Gemini), respectively. In low suspicion studies (PI-RADS 1-2), Bard and Gemini (F1: 0.94, 0.98, respectively) outperformed GPT-3.5 and GTP-4 (F1:0.77, 0.94, respectively), whereas for high probability MRIs (PI-RADS 4-5), GPT-3.5 and GTP-4 (F1: 0.95, 0.98, respectively) outperformed Bard and Gemini (F1: 0.71, 0.87, respectively). Bard assigned a non-existent PI-RADS 6 \"hallucination\" for two patients. Inter-reader agreements (Κ) between the original reports and the senior radiologist, junior radiologist, GPT-3.5, GTP-4, BARD, and Gemini were 0.93, 0.84, 0.65, 0.86, 0.57, and 0.81, respectively.</p><p><strong>Conclusions: </strong>Radiologists demonstrated high accuracy in PI-RADS classification based on text reports, while GPT-3.5 and Bard exhibited poor performance. GTP-4 and Gemini demonstrated improved performance compared to their predecessors.</p><p><strong>Advances in knowledge: </strong>This study highlights the limitations of LLMs in accurately classifying PI-RADS categories from clinical text reports. While the performance of LLMs has improved with newer versions, caution is warranted before integrating such technologies into clinical practice.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142614792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}