British Journal of Radiology最新文献

{"title":"Diagnostic performance of simultaneous multislice diffusion-weighted imaging in differentiating breast lesions: a systematic review and meta-analysis.","authors":"Yuqi Tan, Zheng Ye, Xinyang Lv, Yiteng Zhang, Meng Zhang, Chunchao Xia, Zhenlin Li","doi":"10.1093/bjr/tqae240","DOIUrl":"https://doi.org/10.1093/bjr/tqae240","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the diagnostic performance of simultaneous multislice diffusion-weighted imaging (SMS-DWI) in differentiating malignant and benign breast lesions, and compare it with conventional single shot and readout segmented echo planar imaging without the SMS technique.</p><p><strong>Methods: </strong>The literature search was performed in PubMed, Embase, and Web of Science to identify comparative studies reporting the diagnostic performance of SMS-DWI and conventional DWI in patients with breast lesions. Histopathological analysis was used as a reference standard for malignant breast lesions. The methodological quality was evaluated using QUADAS-2 scale. The summary sensitivity, summary specificity, and area under the curve (AUC) of the summarized receiver operating characteristic curve were calculated and compared between SMS-DWI and conventional DWI using a bivariate random-effects model. Heterogeneity was explored with meta-regression and subgroup analyses.</p><p><strong>Results: </strong>Six studies with 626 patients and 649 breast lesions (benign: 222, malignant: 427) were included. The summary sensitivity, summary specificity, and AUC for SMS-DWI were 0.89 (95% CI: 0.78-0.95), 0.94 (95% CI: 0.81-0.98), and 0.96 (95% CI: 0.94-0.98), respectively, and those for conventional DWI were 0.90 (0.95 CI: 0.84-0.94), 0.87 (95% CI: 0.80-0.92), and 0.94 (95% CI: 0.92-0.96), respectively. The diagnostic performance was not significantly different between SMS-DWI and conventional DWI (P = .337).</p><p><strong>Conclusions: </strong>SMS-DWI has high diagnostic performance in differentiating breast lesions, which is not significantly different from the conventional DWI.</p><p><strong>Advances in knowledge: </strong>There is no significant difference between SMS-DWI and conventional DWI in differentiating breast lesions, suggesting SMS-DWI may be a potential alternative to conventional DWI in breast imaging.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of axial T2-weighted MRI sequence for exclusion of brain tumour in paediatric patients with non-localizing symptoms.","authors":"Amy C Gerrish, Luqman Malik, Charlotte Swain, Adam G Thomas, Timothy Jaspan, Rob A Dineen","doi":"10.1093/bjr/tqae244","DOIUrl":"https://doi.org/10.1093/bjr/tqae244","url":null,"abstract":"<p><strong>Objective: </strong>To establish diagnostic performance of a single axial T2-weighted sequence for detection of brain tumours in children with non-localizing symptoms, compared to a standard MRI protocol.</p><p><strong>Methods: </strong>Retrospective analysis of children undergoing MRI brain imaging for suspected brain tumours with non-localizing symptoms over a 3-year period. Axial T2-weighted images were blindly reviewed by 2 experienced paediatric neuroradiologists. Primary analysis was calculation of diagnostic performance metrics for tumour identification using axial T2-weighted image only compared to the standard MRI protocol.</p><p><strong>Results: </strong>For 312 children undergoing MRI brain during the study period, sensitivity and specificity for brain tumour detection based on axial T2-weighted images in children with non-localizing symptoms were 1.000 (95% CIs 0.598, 1.000) and 0.998 (95% CI 0.990, 0.999), respectively. Based on T2-weighted images alone, 50 patients (16%) were flagged as needing recall for further imaging compared to 14 (4.5%) recalled after the standard protocol.</p><p><strong>Conclusions: </strong>Axial T2-weighted images have high sensitivity and specificity for detection of brain tumours in children with non-localizing symptoms but are associated with increased imaging recall rates. Prospective evaluation of this approach to identify patients requiring more comprehensive imaging is warranted.</p><p><strong>Advances in knowledge: </strong>A truncated MRI protocol with single axial T2-weighted sequence has high diagnostic performance for brain tumour detection in children with non-localizing features. Radiologists can be reassured that a child with this presentation who is unable to complete the full MRI scan protocol is very unlikely to have a brain tumour missed provided an axial T2-weighted sequence is obtained.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addition of contrast-enhanced mammography enhancement patterns and morphology for differentiating benign from malignant papillary breast lesions.","authors":"Weimin Xu, Lingjian Chen, Weixiong Zeng, Zeyuan Xu, Mengwei Ma, Weiguo Chen, Xin Liao, Chanjuan Wen, Sina Wang","doi":"10.1093/bjr/tqae241","DOIUrl":"https://doi.org/10.1093/bjr/tqae241","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the capability of morphological and enhancement pattern analysis in contrast-enhanced mammography (CEM) to differentiate between benign and malignant papillary breast lesions.</p><p><strong>Methods: </strong>This study involved 63 patients diagnosed with papillary breast lesions between January 2018 and December 2022. CEM was performed at two time intervals: between 2-3 min (T1, early phase) and 4-5 min (T2, later phase) after the injection of the contrast agent. For each patient, Breast Imaging Reporting and Data System (BI-RADS) lesion features were recorded. Kinetic enhancement patterns were evaluated for both phases based on these changes, followed by the measurement of diagnostic performance.</p><p><strong>Results: </strong>Among the 63 female patients, a total of 86 lesions were identified, including 18 malignant ones, three intraductal papillomas without atypical proliferation, and 42 benign papillary lesions. The areas under receiver operating characteristic curves for CEM with kinetic enhancement and for CEM alone were 0.856 and 0.800, respectively. Assessing the diagnostic value, specificity, and accuracy of morphological categorization combined with kinetic enhancement showed higher values compared to those of the CEM morphological categorization alone (71.1% vs 60.0% and 79.4% vs 71.4%, respectively). However, the sensitivity and negative predictive value of the CEM with kinetic enhancement were similar to those of CEM alone (100% for all).</p><p><strong>Conclusion: </strong>For BI-RADS 3-5 papillary breast lesions, incorporating CEM kinetic enhancement to morphological patterns improved the confidence level in diagnosis.</p><p><strong>Advances in knowledge: </strong>This article provides valuable references for distinguishing benign and malignant breast papillary lesions.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the risk of hypersensitivity reactions to iopromide differ by sex, race, or across regions/countries? An analysis of 152 233 patients from 4 observational studies and the company's pharmacovigilance database.","authors":"Jan Endrikat, Alexander Ullmann, Christoph Gerlinger, Aasia Bhatti, Philipp Lengsfeld, Alexander Michel","doi":"10.1093/bjr/tqae190","DOIUrl":"10.1093/bjr/tqae190","url":null,"abstract":"<p><strong>Objective: </strong>To analyse the potential impact of patients' sex, race, and region/country on the risk of hypersensitivity reactions after intra-venous or intra-arterial administration of iopromide.</p><p><strong>Methods: </strong>Two analyses were performed. (1) The \"Phase-IV-Analysis\" evaluated an integrated pooled database of 4 non-interventional studies. (2) The \"GPV-Analysis\" evaluated case reports from the company's pharmacovigilance database. The Phase-IV-Analysis was a nested case-control analysis of patients who received an injection of iopromide 300/370 mg iodine/mL. Cases had typical/unequivocal HSRs as defined by the ACR Committee on Drugs and Contrast Media 2018. The global pharmacovigilance (GPV)-Analysis was based on HSR case reports in the company database. Exposure estimates were derived from sales/market research data.</p><p><strong>Results: </strong>The Phase-IV-Analysis comprised 152 233 patients from 37 countries. In the full-analysis set 145 033, 59 412, and 146 649 patients were included in the sex, race, and region/country cohort, respectively. The GPV-Analysis was based on 78.72 million administrations for sex and 118.56 million administrations for region/country. No GPV exposure data by race were available. Sex: Phase-IV-Analysis: The HSR incidence was significantly higher for women (0.72%) vs men (0.55%) (P ≤ .0001). The unadjusted odds ratio (OR) was 1.3 (95% CI, 1.154-1.499), the adjusted OR was 1.156 (95% CI, 1.006-1.328) (P = .04). GPV-Analysis: Reporting rates were 0.0102% for women and 0.0075% for men (P < .0001). OR: 1.36 (95% CI, 1.3-1.43). Race: Phase-IV-Analysis: No significantly different HSR incidences for white (0.70%) and Asian (0.61%) patients (P = .3094) were detected. Region/country: Phase-IV-Analysis: The overall world HSR-incidence was 0.62%. Europe: 0.52%, Asia: 0.70%, United States: 0.75%, Germany: 0.51%, China: 0.41%, South Korea: 0.76%. GPV-Analysis: The overall world HSR-reporting rate was 0.015%, varying across regions/countries.</p><p><strong>Conclusion: </strong>Women showed a slightly higher risk for HSRs than men. Impact of race was not found. HSR-reporting varied by region/country.</p><p><strong>Advances in knowledge: </strong>Risk for HSRs was increased by female sex but not by race or region/country.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"2004-2014"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Efficacy of needle tract embolization using gelfoam in reducing incidence of Pneumothorax in CT-guided transthoracic Lung Biopsies: A Systematic Review and Meta-analysis.\"","authors":"Parneet Singh, Manoj Kumar Nayak, Tejasvini Singhal, Girish Kumar Parida, Kanhaiyalal Agrawal, Biswajit Sahoo, Nerbadyswari Deep Bag","doi":"10.1093/bjr/tqae228","DOIUrl":"https://doi.org/10.1093/bjr/tqae228","url":null,"abstract":"<p><strong>Objective: </strong>Transthoracic CT-guided lung biopsy is associated with risk of pneumothorax, requiring chest tube placement at times. From available literature, we tried to compare the incidence rate of pneumothorax in cases undergoing CT-guided lung biopsy with versus without use of gelfoam slurry for tract occlusion.</p><p><strong>Methods: </strong>Databases like SCOPUS, PubMed, Google Scholar and EMBASE were searched for original studies analyzing the efficacy of gelfoam for needle tract embolization following CT-guided lung biopsy till September 2023. Bias in the selected studies was assessed using the Risk Of Bias In Non-randomized Studies of Interventions (ROBINS-I) tool. Pooled odds ratio of the effect of gelfoam slurry on the rate of pneumothorax and chest tube placement following CT-guided lung biopsy was calculated and represented with 95% confidence intervals (95% CI) and Prediction interval (PI).</p><p><strong>Results: </strong>Pooled analysis of six studies, revealed that patients undergoing needle tract embolization when compared to non-embolized patients had a significantly decreased risk of pneumothorax with odds reduced by 59% (OR = 0.41, 95% CI = 0.25-0.66, p = 0.01; PI=-1.694-0.094). Also, it led to a significant reduction in severe pneumothorax requiring chest tube placement with reduced odds by 63% (OR = 0.37, 95%CI= 0.20-0.69, p = 0.01; PI=-1.855-0.115).</p><p><strong>Conclusion: </strong>Needle tract embolization using gelfoam has a significant protective effect against pneumothorax as well as chest tube insertion in patients undergoing CT-guided lung biopsy.</p><p><strong>Advances in knowledge: </strong>Gelfoam needle tract embolization can effectively reduce the risk of pneumothorax and chest tube requirement after lung biopsy.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric Magnetic Resonance Imaging Assessment of Primary Tumors for Predicting Axillary Tumor Burden in Women with Invasive Breast Cancer.","authors":"Jin Joo Kim, Jin You Kim, Kyung Jin Nam, Kye Young Lee, Ki Seok Choo, Taewoo Kang, Heeseung Park, Seong Hwan Bae","doi":"10.1093/bjr/tqae243","DOIUrl":"https://doi.org/10.1093/bjr/tqae243","url":null,"abstract":"<p><strong>Objective: </strong>To assess the association between multiparametric MRI features of primary tumors and axillary lymph node tumor burden in women with invasive breast cancer.</p><p><strong>Methods: </strong>In this retrospective study, women diagnosed with invasive breast cancer who underwent 3T multiparametric MRI, including diffusion-weighted imaging (DWI) from 2019-2020, were evaluated. Two radiologists reviewed T2-weighted images (T2WI) for peritumoral edema and intratumoral necrosis, and measured apparent diffusion coefficient (ADC) values by manually placing regions of interest within breast tumors. We also analyzed quantitative kinetic features of breast cancer using computer-aided diagnosis (CAD) and clinical-pathologic characteristics. Uni- and multivariable logistic regression analyses were conducted to identify predictors of a high axillary nodal burden (≥3 positive nodes).</p><p><strong>Results: </strong>In total, 301 women (mean age, 54.13 years) were evaluated. Forty-three (14.3%) had a high axillary nodal burden by surgical pathology. Multivariate analysis revealed that factors significantly associated with high axillary nodal burden included peritumoral edema (OR:7.970; p<0.001), lower tumor ADCmax (≤ 1.098 × 10-3 mm2/s) (OR:6.978; p<0.001), larger tumor size (>2cm) (OR:2.986; p=0.046), lobular histology (OR:12.620; p<0.001), and the presence of lymphovascular invasion (OR:3.622; p=0.003). CAD-derived kinetic features did not show an association with axillary nodal burden. In subgroup analysis of 238 patients with early clinically node-negative breast cancer, both peritumoral edema (OR:7.831; p=0.002) and lower tumor ADCmax (≤ 1.098 × 10-3 mm2/s) (OR:8.002; p=0.002) remained significant predictors.</p><p><strong>Conclusion: </strong>Our results suggest that peritumoral edema as viewed in T2WI and the ADCmax value of breast cancer in DWI are valuable for predicting axillary nodal burden in women with invasive breast cancer.</p><p><strong>Advances in knowledge: </strong>Multiparametric MRI features of a primary tumor are useful for predicting axillary nodal burden in patients with invasive breast cancer.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging and endovascular management of haemoptysis in congenital heart disease.","authors":"Vimal Chacko, Dr Jayakrishana, Jineesh Valakkada, Anoop Ayappan, Santhosh Kannath, Deepa S Kumar, Arun Goplakrishana","doi":"10.1093/bjr/tqae239","DOIUrl":"https://doi.org/10.1093/bjr/tqae239","url":null,"abstract":"<p><p>Haemoptysis, a rare but serious complication that can arise in patients with congenital heart disease (CHD), necessitates prompt diagnosis and specialised care. The radiologist plays a critical role in this scenario, including identifying the source of haemoptysis, devising treatment plans, and delivering endovascular interventions. This article highlights the importance of imaging techniques, especially computed tomography (CT), in identifying the cause of haemoptysis and the therapeutic value of endovascular interventions. Furthermore, a suggested algorithmic approach is presented to assist with the diagnostic and management process.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversible Electroporation for Cancer Therapy.","authors":"Taha Shiwani, Simran Dhesi, Tze Min Wah","doi":"10.1093/bjr/tqae231","DOIUrl":"https://doi.org/10.1093/bjr/tqae231","url":null,"abstract":"<p><p>Reversible electroporation refers to the use of high voltage electrical pulses on tissues to increase cell membrane permeability. It allows targeted delivery of high concentrations of chemotherapeutic agents including cisplatin and bleomycin, a process known as electrochemotherapy (ECT). It can also be used to deliver toxic concentrations of calcium and gene therapies that stimulate an anti-tumour immune response. ECT was validated for palliative treatment of cutaneous tumours. Evidence to date shows a mean objective response rate of ∼80% in these patients. Regression of non-treated lesions has also been demonstrated, theorised to be from an in-situ vaccination effect. Advances in electrode development have also allowed treatment of deep-seated metastatic lesions and primary tumours, with safety demonstrated in vivo. Calcium electroporation and combination immunotherapy or immunogene electrotransfer is also feasible, but research is limited. Adverse events of ECT are minimal; however, general anaesthesia is often necessary, and improvements in modelling capabilities and electrode design are required to enable sufficient electrical coverage. International collaboration between preclinical researchers, oncologists and interventionalists is required to identify the most effective combination therapies, to optimise procedural factors, and to expand use, indications and assessment of reversible electroporation. Registries with standardised data collection methods may facilitate this.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gadoxetic Acid-Enhanced MRI in Differentiating Focal Nodular Hyperplasia from Hepatocellular Adenoma in Children.","authors":"Başak Erdemli Gürsel, Gökhan Öngen, Selman Candan, Nadide Başak Gülleroğlu, Betül Berrin Sevinir, Zeynep Yazıcı","doi":"10.1093/bjr/tqae222","DOIUrl":"https://doi.org/10.1093/bjr/tqae222","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the diagnostic performance of Gd-EOB-enhanced magnetic resonance imaging (MRI) for distinguishing focal nodular hyperplasia (FNH) from hepatocellular adenoma (HCA) in children.</p><p><strong>Methods: </strong>Twenty-two patients (6 with HCA and 16 with FNH) were retrospectively included in this study. After qualitative analyses of MRI, quantitative analyses were performed by calculating the relative signal intensity ratios (SIR) between lesion and liver parenchyma both on precontrast and hepatobiliary phase images. Two equations, SIRpost-pre and liver-to-lesion contrast enhancement ratio (LLCER), using both SIRs of precontrast and hepatobiliary phase (HBP) imaging together were also calculated.</p><p><strong>Results: </strong>The most distinguishing non-contrast-enhanced MRI feature of HCA was intralesional fat since all HCA contained fat but none of FNHs. All FNHs were iso- or hyperintense relative to the adjacent liver on HBP images, but all HCAs except one were hypointense. The mean SIRpost-pre and LLCER of FNH were significantly higher than that of HCA (p < 0,001). SIRpost-pre and LLCER provided sensitivity and specificity values of 100%.</p><p><strong>Conclusion: </strong>Although intralesional fat is a strong discriminative feature for distinguishing between HCA and FNH, qualitative properties of these lesions may not be enough for confident diagnosis. Gd-EOB uptake in the HBP provides high diagnostic accuracy, but overlap can be seen. SIRpost-pre and LLCER overcome the difficulties and have the best sensitivity and specificity.</p><p><strong>Advances in knowledge: </strong>Although there are many similar studies in adult group, this is one of the rare studies that will contribute to the literature in the pediatric group.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality assurance in lung cancer screening.","authors":"Adnan G Taib, Iain T H Au-Yong, Arjun Nair, Anand Devaraj, Yan Chen, David R Baldwin","doi":"10.1093/bjr/tqae229","DOIUrl":"https://doi.org/10.1093/bjr/tqae229","url":null,"abstract":"<p><p>The effectiveness of screening programmes is critically dependent on the accuracy of the screening test. Where this relies on clinical expertise, there is an imperative to assure that the level of expertise meets expected standards. In cancer screening involving images, the focus is on the reader. Auditing of results is fraught with difficulty because of the time taken to accumulate enough data with confirmed outcomes to identify underperformance before any harm is done. Late recognition can lead to the need for reanalysis and recall of screening participants with loss of confidence in the programme. External Quality Assurance (EQA) is a method that enables clinical expertise to be tested rapidly by using test datasets with confirmed clinical outcome. In the UK, the breast cancer screening programme has had EQA in place for over 30 years. This article describes the development of the first EQA process in lung cancer screening, using the experience gained from running the breast cancer EQA, and the proposed future developments.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}