Sian Cooper, Joan Chick, Francis Casey, Sophie Alexander, Simeon Nill, Uwe Oelfke, Alison Tree, Alex Dunlop
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引用次数: 0
Abstract
Objectives: The standard radiotherapy (RT) pathway faces bottlenecks. The RACE study aims to evaluate the feasibility and safety of "simulation-free" radiotherapy (SFRT) by using diagnostic, non-radiotherapy-dedicated magnetic resonance (MR) scans for planning prostate cancer treatments with MRI-guided online adaptive radiotherapy (MRIgART).
Methods: In the first step of RACE, we conducted an audit of prostate cancer patients who received 5-fraction stereotactic body radiotherapy(SBRT) between March 2023 and January 2024, evaluating their diagnostic MRI scans for potential use in RT planning. The key requirements for planning suitability were a T2-weighted sequence for target/OAR delineation and a large field-of-view scan for body contour and bones, with scans categorized as either fully suitable or having specific issues (incomplete body coverage or slice thickness >10mm). Workflow analysis measured time intervals between RT referral, planning MRI, and first fraction to quantify potential time savings from SRFT.
Results: Diagnostic MRIs were available for 93% of patients, with scans originating from various hospitals and conducted on 1.5 Tesla (T) or 3T MRI scanners. Ideal image characteristics for RT planning were met in 31% of MRIs. Issues such as cropped field of view (FOV) and low slice resolution were identified, but proposed solutions could increase the number of patients with suitable scans to 87%.
Conclusions: The findings suggest that with appropriate technical solutions, most diagnostic MRI scans can be adapted for RT planning purposes.
期刊介绍：
BJR is the international research journal of the British Institute of Radiology and is the oldest scientific journal in the field of radiology and related sciences.
Dating back to 1896, BJR’s history is radiology’s history, and the journal has featured some landmark papers such as the first description of Computed Tomography "Computerized transverse axial tomography" by Godfrey Hounsfield in 1973. A valuable historical resource, the complete BJR archive has been digitized from 1896.
Quick Facts:
- 2015 Impact Factor – 1.840
- Receipt to first decision – average of 6 weeks
- Acceptance to online publication – average of 3 weeks
- ISSN: 0007-1285
- eISSN: 1748-880X
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