Nanoscale最新文献_第3页

Electrospun natural product-based Shidu Formula for the management of psoriasis 以电纺天然产品为基础的牛皮癣石毒配方治疗

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-07-01 DOI: 10.1039/d5nr01873k

Ruodan Xu, Mengyuan Zhou, Yi Tang, Can Cao, Yanxin Jiang, Jing Li, Chen Wang, Xi Wu, Ping Song, Ning Li

{"title":"Electrospun natural product-based Shidu Formula for the management of psoriasis","authors":"Ruodan Xu, Mengyuan Zhou, Yi Tang, Can Cao, Yanxin Jiang, Jing Li, Chen Wang, Xi Wu, Ping Song, Ning Li","doi":"10.1039/d5nr01873k","DOIUrl":"https://doi.org/10.1039/d5nr01873k","url":null,"abstract":"The Shidu Formula (SDF) ointment is a natural product-based medicine that has a long history of use in treating psoriasis. Compared to standard first-line clinical medications, SDF remedies present certain advantages, particularly in terms of causing minimal skin irritations. However, several challenges have limited their widespread applications. These include the sticky nature of SDF ointments, which can hinder drug penetration and lead to staining of the skin and clothing, and delayed onset of effects that often necessitates higher dosages. Therefore, the development of innovative topical solutions is highly required to deliver the complex components of SDF effectively. In this study, we developed an amphiphilic blended membrane of polycaprolactone (PCL) and polyethylene oxide (PEO) using electrospinning, successfully transforming the SDF ointment into nanofibrous meshes. We confirmed that it was feasible to incorporate a maximum of 5% SDF through morphological, physiological, and pharmacological assessment. The release profile of the principal active components verified that berberine chloride and gallnut were released in bursts. <em>In vivo</em> experiments further demonstrated the benefits and biocompatibility of the SDF–PCL/PEO membrane in the management of IMQ-induced psoriasis-like skin inflammation, as demonstrated by severity index scoring and pathological evaluations. Notably, converting the ointment into nanofibrous meshes addressed the typical challenges associated with conventional SDF ointment, resulting in significantly improved efficacy, short application times, controllable dosages, and reduced staining of the skin and clothes. This work provides a promising approach for transforming complex natural products into effective external treatment options for psoriasis.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"2 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Passive nanorheological tool to characterise hydrogels 纠正：被动纳米流变工具表征水凝胶

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-07-01 DOI: 10.1039/d5nr90126j

Moira Lorenzo Lopez, Victoria R. Kearns, Eann A. Patterson, Judith M. Curran

引用次数: 0

Dispersion of carbon nanotubes triggered by helical self-assembly of poly(methyl methacrylate) 聚甲基丙烯酸甲酯螺旋自组装引发碳纳米管分散

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-07-01 DOI: 10.1039/d5nr01706h

Ayaka Inoue, Kazuhiro Yoshida, Tsuyoshi Ando, Shuta Fukuura, Takashi Yumura, Hiroharu Ajiro, Tsuyoshi Kawai, Yoshiyuki Nonoguchi

引用次数: 0

Unravelling Chemical Heterogeneity and Dual Emission Pathways in Graphene Quantum Dots via Single-Particle Infrared Spectroscopy 利用单粒子红外光谱研究石墨烯量子点的化学非均质性和双发射途径

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-07-01 DOI: 10.1039/d5nr01811k

SUBHRO KUNDU, ABU BAKAR SIDDIQUE, Irvin Fernando Guzmán González, Kevin Armando Rodríguez Mireles, Maritza Iveth Perez Valverde, Nicolás Antonio Ulloa-Castillo, Madhusoodanan Reghunathan, Domingo Ixcoatl Garcia-Gutierrez, Eduardo Martínez, Mallar Ray

{"title":"Unravelling Chemical Heterogeneity and Dual Emission Pathways in Graphene Quantum Dots via Single-Particle Infrared Spectroscopy","authors":"SUBHRO KUNDU, ABU BAKAR SIDDIQUE, Irvin Fernando Guzmán González, Kevin Armando Rodríguez Mireles, Maritza Iveth Perez Valverde, Nicolás Antonio Ulloa-Castillo, Madhusoodanan Reghunathan, Domingo Ixcoatl Garcia-Gutierrez, Eduardo Martínez, Mallar Ray","doi":"10.1039/d5nr01811k","DOIUrl":"https://doi.org/10.1039/d5nr01811k","url":null,"abstract":"Understanding the relationship between local chemical structure and photoluminescence (PL) in graphene quantum dots (GQDs) and nitrogen-functionalized GQDs (N-GQDs) is critical for their advancement in optoelectronics, sensing, and bioimaging. Ensemble measurements mask the structural and functional heterogeneity intrinsic with these quasi-zero-dimensional systems. Here, we employ single-particle photo-induced force microscopy (PiFM) to chemically map individual GQDs and N-GQDs, revealing diverse surface functional groups and bonding architectures that are obscured in bulk analyses. PiF-IR spectra correlate well with vibrational modes predicted by density functional theory (DFT) on model structures incorporating oxygen and nitrogen functionalities. While ensemble characterizations such as Raman spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy support the findings of single-particle analysis, the latter offers significantly superior spatial and chemical resolution. Optical features of the GQDs and the NGQDs show size and chemical structure-dependent behaviour such as excitation-dependent emission thresholds and biexponential decay dynamics. These observations support a dual recombination mechanism involving band-edge-to-band-edge transitions and surface / dopant-mediated transition pathways. By integrating these methods, we establish a robust framework for connecting structure to optical behaviour highlighting the importance of single-particle studies for rational design of carbon-based quantum materials.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"12 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gradient CNT/PMN-PT/PVDF Piezoelectric Composites for Gait Monitoring during Weight-Bearing Walking 梯度CNT/PMN-PT/PVDF压电复合材料在负重行走中的步态监测

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-07-01 DOI: 10.1039/d5nr02020d

Weili Deng, Tingting Zhou, Wanghong Zeng, Zihan Wang, Yiheng Liu, Boling Lan, Shenglong Wang, Yong Ao, Yue Sun, Shuai Wang, Zhaoyu Li, Long Jin, Weiqing Yang

{"title":"Gradient CNT/PMN-PT/PVDF Piezoelectric Composites for Gait Monitoring during Weight-Bearing Walking","authors":"Weili Deng, Tingting Zhou, Wanghong Zeng, Zihan Wang, Yiheng Liu, Boling Lan, Shenglong Wang, Yong Ao, Yue Sun, Shuai Wang, Zhaoyu Li, Long Jin, Weiqing Yang","doi":"10.1039/d5nr02020d","DOIUrl":"https://doi.org/10.1039/d5nr02020d","url":null,"abstract":"Wearable piezoelectric sensors have gained significant attention for real-time biomechanical monitoring, yet existing designs often face limitations in sensitivity, durability, and dynamic response. To address these challenges, we develop a wearable sensor utilizing gradient-architected CNT/PMN-PT/PVDF piezoelectric composites for continuous gait monitoring during weight-bearing walking. The sensor features a dual-filler gradient configuration within the poly(vinylidene fluoride) (PVDF) matrix, where strategically distributed carbon nanotubes (CNTs) and lead magnesium niobate-lead titanate (PMN-PT) ceramic particles synergistically enhance electromechanical coupling efficiency. The CNTs-enriched surface layer boosts polarization by facilitating charge injection efficiency, while the gradient-arranged PMN-PT fillers induce stress concentration, further amplifying the piezoelectric output. As a result, the sensor exhibits exceptional performance, with a decent piezoelectric coefficient (d33* = 40 pm/V) and high sensitivity (172 mV/N). Both experimental tests and finite element simulations validate the superior performance of this gradient structure, making it highly effective for real-time kinematic monitoring during weight-bearing walking. This composite-based sensor represents a promising advancement in wearable health technology, with immediate applications in clinical gait analysis, rehabilitation monitoring and sports injury prevention.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"13 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Upconversion Nanohybrids for NIR-Induced Photorepair of DNA Etheno Adducts nir诱导DNA乙二烯加合物光修复的上转换纳米杂化体

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-06-30 DOI: 10.1039/d5nr01777g

Laura Frances-Soriano, Gemma Maria M. Rodríguez, Paloma Lizondo-Aranda, Delia Bellezza, María González-Béjar, Virginie Lhiaubet-Vallet

引用次数: 0

ZnO Quantum Dots as an Electron-Transport Layer for Highly Efficient and Stable Organic Solar Cells ZnO量子点作为高效稳定有机太阳能电池的电子传输层

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-06-30 DOI: 10.1039/d5nr01722j

Abdus Saboor, Oleksandr L. Stroyuk, Oleksandra Raievska, Chao Liu, Jens Hauch, Christoph J Brabec

引用次数: 0

Tunable resonant Raman scattering with temperature in vertically aligned 2H-SnS2 垂直排列2H-SnS2中随温度变化的可调谐共振拉曼散射

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-06-30 DOI: 10.1039/d5nr01717c

Atul Gangaram Chakkar, Deepu Kumar, Ashok Kumar, Mahesh Kumar, Pradeep Kumar

引用次数: 0

Room-Temperature Solution-Processed Spin Organic Light-Emitting Diodes Based on Chiral 2D Halide Perovskites 基于手性二维卤化物钙钛矿的室温溶液处理自旋有机发光二极管

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-06-30 DOI: 10.1039/d5nr01117e

Lan-Sheng Yang, Chun-Yao Huang, Chin-An Hsu, Hao-Zhe Chiu, Pei-Hsuan Lo, Yu-Chiang Chao

{"title":"Room-Temperature Solution-Processed Spin Organic Light-Emitting Diodes Based on Chiral 2D Halide Perovskites","authors":"Lan-Sheng Yang, Chun-Yao Huang, Chin-An Hsu, Hao-Zhe Chiu, Pei-Hsuan Lo, Yu-Chiang Chao","doi":"10.1039/d5nr01117e","DOIUrl":"https://doi.org/10.1039/d5nr01117e","url":null,"abstract":"Chiral R-/S-methylbenzylamine (R-/S-MBA) was used as cation to form chiral 2D perovskites with different stoichiometric ratios ⟨n⟩ and halide compositions. The chiroptical properties of chiral perovskites, as well as their application in chiral spintronics, were investigated. The chemical composition and chiroptical properties of these materials were investigated by X-ray diffraction, circular dichroism (CD), magnetic CD (MCD), circularly polarized luminescence (CPL) and magnetic CPL (MCPL). Large Stokes shifts were observed when the halide composition of perovskite films with ⟨n⟩ = 1 was changed from iodide-rich to bromide-rich. Furthermore, circularly polarized electroluminescence was observed at room temperature in the absence of an external magnetic field. The degree of spin current polarization of 2D chiral perovskites reaches 86%. In terms of applications of spin device applications, spin organic light-emitting diodes were realized by using chiral 2D perovskite films with different halide compositions as the spin filters and using a polymer called Super Yellow as the emissive layer. The halide composition of the spin filter does not affect the emission wavelength of the device. A maximum gCP-EL of 1 × 10−2 was obtained. The chiroptical properties of chiral halide perovskites demonstrated in this work are useful for chiroptoelectronics and chiral spintronics.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"62 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144515487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electronic and structural coupling of pentacene on NiO(001) 并五苯在NiO（001）上的电子和结构耦合

IF 6.7 3区材料科学

Nanoscale Pub Date : 2025-06-30 DOI: 10.1039/d5nr00700c

Jonah Elias Nitschke, David Maximilian Janas, Stefano Ponzoni, Michele Capra, Elena Molteni, Andrea Picone, Alessio Giampietri, Alessandro Ferretti, Shuangying Ma, Alberto Brambilla, Giovanni Zamborlini, Guido Fratesi, Mirko Cinchetti

{"title":"Electronic and structural coupling of pentacene on NiO(001)","authors":"Jonah Elias Nitschke, David Maximilian Janas, Stefano Ponzoni, Michele Capra, Elena Molteni, Andrea Picone, Alessio Giampietri, Alessandro Ferretti, Shuangying Ma, Alberto Brambilla, Giovanni Zamborlini, Guido Fratesi, Mirko Cinchetti","doi":"10.1039/d5nr00700c","DOIUrl":"https://doi.org/10.1039/d5nr00700c","url":null,"abstract":"Transition-metal oxides (TMOs) are pivotal in modern applications, with recent years seeing intensified research into their interplay with molecular layers as well as the potential of antiferromagnetic TMOs in spintronic applications. In this work we combine both approaches and investigate the adsorption of pentacene on the (001) surface of NiO. By employing a variety of methods such as scanning tunneling microscopy, low energy electron diffraction, angle-resolved photoelectron spectroscopy and density functional theory, we extract the geometrical arrangement of the molecules and their energy level-alignment. Induced by the substrate–molecule interaction, pentacene forms a self-assembled monolayer in a superstructure commensurate with the NiO substrate. Through photoemission orbital tomography, we identify the first three highest occupied molecular orbitals (HOMO, HOMO−1 and HOMO−2) in the photoemission spectra of the NiO/pentacene interface. The absence of the lowest unoccupied molecular orbital (LUMO) suggests negligible charge transfer at the interface, a finding supported by calculations. Nevertheless, we can observe an induced degeneracy of the HOMO−1 and HOMO−2 orbitals as well as an accumulation of molecular electron density toward the substrate. This preservation of the molecules free electron character of frontier orbitals points to potential applications in the optical control of THz spin dynamics in antiferromagnetic NiO, opening a promising pathway for engineering molecule-based functionalization of antiferromagnetic surfaces.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"655 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0