Nanoscale最新文献_第10页

Construction of Sc-NiFe-LDH electrocatalyst for highly efficient electrooxidation of 5-hydroxymethylfurfural at industrial current density

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-09 DOI: 10.1039/d4nr04389h

Changlong Wang, Yufeng Wu, Zhiyan Hou

引用次数: 0

Film thickness dependence of nanoscale arrangement of a chiral electron donor in its blends with an achiral electron acceptor

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-09 DOI: 10.1039/d4nr04269g

Giulia Pancotti, Elizabeth Killalea, Thomas Wheildon Rees, Letizia Liirò-Peluso, Sergi Riera-Galindo, Peter Beton, Mariano Campoy-Quiles, David B Amabilino, Giuliano Siligardi

{"title":"Film thickness dependence of nanoscale arrangement of a chiral electron donor in its blends with an achiral electron acceptor","authors":"Giulia Pancotti, Elizabeth Killalea, Thomas Wheildon Rees, Letizia Liirò-Peluso, Sergi Riera-Galindo, Peter Beton, Mariano Campoy-Quiles, David B Amabilino, Giuliano Siligardi","doi":"10.1039/d4nr04269g","DOIUrl":"https://doi.org/10.1039/d4nr04269g","url":null,"abstract":"The nanoscale chiral arrangement in a bicomponent organic material system comprising donor and acceptor small molecules is shown to depend on the thickness of a film that is responsive to chiral light in an optoelectronic device. In this bulk heterojunction, a previously unreported chiral bis(diketopyrrolopyrrole) derivative was combined with an achiral non-fullerene acceptor. The optical activity of the chiral compound is dramatically different in the pure material and the composite, showing how the electron acceptor influences the donor’s arrangement compared with the pure molecule. Mueller matrix polarimetric imaging shows the authenticity of this effect and the homogeneity of short range chiral orientations between the molecules, as well as more heterogeneous short and longer range arrangements in the films observed in linear dichroic and birefringent effects. The two-dimensional circular dichroism (CD) maps and spectra show the uniformity of the short range supramolecular interactions both in spun-cast films on quartz and blade-coated films on photovoltaic device substrates, where evidence for the chiral arrangement is uniquely provided by the synchrotron CD measurements. The external quantum efficiency of the devices depends upon the handedness of the light used to excite them and the film thickness, that influences the supramolecular arrangement and organization in the film, and determines the selectivity for left or right circularly polarised light. The difference in external quantum efficiency of the photovoltaic devices between the two handedness’ of light correlates with the apparent differential absorbance (g-factor) of the films.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"20 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Promising Role of Noble Metal NPs@MOFs in Chondrosarcoma Management

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-09 DOI: 10.1039/d4nr03878a

Ziheng Huang, Keyue Tian, Yiyuan Xue, Feng Luo

引用次数: 0

Versatile Role of Oleylamine in the Controlled Synthesis of Copper Nanoparticles with Diverse Morphologies

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-09 DOI: 10.1039/d4nr04079a

Sonia Hadaoui, Giang Tran, Ahmed Naitabdi, Alexa Courty

{"title":"Versatile Role of Oleylamine in the Controlled Synthesis of Copper Nanoparticles with Diverse Morphologies","authors":"Sonia Hadaoui, Giang Tran, Ahmed Naitabdi, Alexa Courty","doi":"10.1039/d4nr04079a","DOIUrl":"https://doi.org/10.1039/d4nr04079a","url":null,"abstract":"Precise tuning of ligands and a comprehensive understanding of their roles and functionalities are crucial for the design of nanoparticles (NPs) with tailored properties. In this study, we present the synthesis of copper NPs with precise control over their shape and crystallinity, relying on the remarkable versatility of oleylamine (OLA) as both a solvent and a ligand. By adjusting the temperature, OLA enables the formation of cubic NPs under rapid heating, reflecting kinetic control, and octahedral NPs with slow heating, indicating thermodynamic control. XPS analysis of these NPs reveals that OLA's dual chemical functionality allows for the stabilization of cubic NP (100) facets through surface binding via its alkene group, while octahedral and quasi-spherical NPs are stabilized by OLA's attachment to (111) facets through its amine function. Besides, this study highlights how trioctyl phosphine oxide (TOPO) and trioctyl phosphine (TOP) contribute to controlling nucleus crystallinity at early synthesis stages, facilitating the selective formation of single-crystal particles or multiply twinned particles. OLA’s dual role, as both solvent and ligand, enhances its ability to stabilize different crystalline facets, making it a powerful tool for synthesizing copper NPs with diverse and controlled morphologies. This versatility opens up possibilities for tailoring their catalytic properties to specific applications","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"83 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Optoelectronic Properties of SnS via Mixed Phase Heterostructure Engineering

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-09 DOI: 10.1039/d4nr04303k

Dhanjit Talukdar, Dambarudhar Mohanta, Gazi Ameen Ahmed

{"title":"Enhancing Optoelectronic Properties of SnS via Mixed Phase Heterostructure Engineering","authors":"Dhanjit Talukdar, Dambarudhar Mohanta, Gazi Ameen Ahmed","doi":"10.1039/d4nr04303k","DOIUrl":"https://doi.org/10.1039/d4nr04303k","url":null,"abstract":"SnS holds great promise in optoelectronics, especially in photovoltaic devices, due to its exceptional intrinsic electronic properties and optimal optical absorption. However, its prospective applications are often limited by structural instability or oxidation, leading to internal or external defect states. This study proposes a mixed-phase SnS/h-BN heterostructure to enhance chemical and thermal stability while preserving the intrinsic optoelectronic properties of SnS. High negative binding energy and ab initio molecular dynamics simulations confirm the structural and thermal stability of the heterostructure up to 600 K. The heterostructure exhibits a type-I band alignment with an indirect density functional theory (DFT) band gap of 1.38 eV, corrected to 2.20 eV using Green’s function with screened Coulomb potential (GW) calculations. The vertical intralayer electric field, resulting from non-uniformity in charge dynamics within the heterostructure, influences the SnS bound excitons, causing reduction in their binding energies. The weakly bound excitons indicate to effective charge separation, charge transport augmentation, and prolonged recombination lifetime. The interface effectively combines the excellent light-harvesting capabilities of SnS with the remarkable stability of h-BN, retaining the desirable optoelectronic properties of SnS while offering enhanced charge transport and stability.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"117 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of Absolute Intramolecular Distances in Proteins by Anomalous X-ray Scattering Interferometry

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-09 DOI: 10.1039/d4nr03375b

Samuel Stubhan, Anna V. Baptist, Caroline Körösy, Alessandra Narducci, Gustavo Gabriel Moya Muñoz, Nicolas Wendler, Aidin Lak, Michael Sztucki, Thorben Cordes, Jan Lipfert

{"title":"Determination of Absolute Intramolecular Distances in Proteins by Anomalous X-ray Scattering Interferometry","authors":"Samuel Stubhan, Anna V. Baptist, Caroline Körösy, Alessandra Narducci, Gustavo Gabriel Moya Muñoz, Nicolas Wendler, Aidin Lak, Michael Sztucki, Thorben Cordes, Jan Lipfert","doi":"10.1039/d4nr03375b","DOIUrl":"https://doi.org/10.1039/d4nr03375b","url":null,"abstract":"Biomolecular structures are typically determined using frozen or crystalline samples. Measurement of intramolecular distances in solution can provide additional insights into conformational heterogeneity and dynamics of biological macromolecules and their complexes. The established molecular ruler techniques used for this (NMR, FRET, and EPR) are, however, limited in their dynamic range and require model assumptions to determine absolute distance (distributions). Here, we introduce anomalous X-ray scattering interferometry (AXSI) for intramolecular distance measurements in proteins, which are labeled at two sites with small gold nanoparticles of 0.7 nm radius. We apply AXSI to two different cysteine-variants of maltose binding protein in the presence and absence of its ligand maltose and find distances in quantitative agreement with single-molecule FRET experiments. Our study shows that AXSI enables determination of intramolecular distance distributions under virtually arbitrary solution conditions and we anticipate its broad use to characterize protein conformational ensembles and dynamics.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"14 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuning Optical Properties of Gold Nanoparticles via Photoactive Liquid Crystalline Azo Ligands

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-09 DOI: 10.1039/d4nr03771e

Sachin Bhat, Shankar D. Rao, S. Krishna Prasad, Channabasaveshwar Yelamaggad

{"title":"Tuning Optical Properties of Gold Nanoparticles via Photoactive Liquid Crystalline Azo Ligands","authors":"Sachin Bhat, Shankar D. Rao, S. Krishna Prasad, Channabasaveshwar Yelamaggad","doi":"10.1039/d4nr03771e","DOIUrl":"https://doi.org/10.1039/d4nr03771e","url":null,"abstract":"In the field of modern nanoscience, the ability to tailor the properties of nanoparticles is essential for advancing their applications. A key approach to achieving this control involves manipulating surface plasmon resonance (SPR) to modify optical properties. This study introduces a novel method for synthesizing gold nanoparticles capped with photoactive liquid crystalline azo ligands, accomplished without reducing agents. Comprehensive structural characterization was performed using Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), ultraviolet-visible (UV-Vis) spectroscopy, powder X-ray diffraction (PXRD), and high-resolution transmission electron microscopy (HRTEM). Photophysical investigations, including time-dependent UV-Vis and fluorescence spectroscopy, provided insights into the modulation of SPR. The mesomorphic behavior of the azo ligands was examined through polarized optical microscopy (POM), differential scanning calorimetry (DSC), and X-ray diffraction (XRD), revealing a chiral lamellar superstructure confirmed by circular dichroism (CD) spectroscopy. Notably, the photoactive azo ligands demonstrated significant control over SPR peak modulation, enabling precise manipulation of nanoparticle size and arrangement. This research highlights the potential of photoactive ligands in the design of nanoparticles with tailored optical properties, paving the way for innovative applications in various fields.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"37 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Face-controlled chirality induction in octahedral thiacalixarene-based porous coordination cages

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-09 DOI: 10.1039/d4nr03622k

Ivan V. Khariushin, Alexander S. Ovsyannikov, Stéphane A. Baudron, Jas S. Ward, Anniina Kiesilä, Kari Rissanen, Elina Kalenius, Matthieu Chessé, Beata Nowicka, Svetlana E. Solovieva, Igor S. Antipin, Véronique Bulach, Sylvie Ferlay

引用次数: 0

Recent Advances in SERS Assays for Detection of Multiple Extracellular Vesicles Biomarkers for Cancer Diagnosis

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-07 DOI: 10.1039/d4nr04014g

Chloe Duffield, Laura Marcela Rey Gomez, Simon Chang-Hao Tsao, Yuling Wang

{"title":"Recent Advances in SERS Assays for Detection of Multiple Extracellular Vesicles Biomarkers for Cancer Diagnosis","authors":"Chloe Duffield, Laura Marcela Rey Gomez, Simon Chang-Hao Tsao, Yuling Wang","doi":"10.1039/d4nr04014g","DOIUrl":"https://doi.org/10.1039/d4nr04014g","url":null,"abstract":"As the prevalence of cancer is escalating, there is an increased demand for early and sensitive diagnostic tools. A major challenge in early detection is the lack of specific biomarkers, and a readily accessible, sensitive and rapid detection method. To meet these challenges, cancer-derived small extracellular vesicles (sEVs) have been discovered as a new promising cancer biomarker due to the high abundance of sEVs in body fluids and their extensive cargo of biomarkers. Additionally, surface-enhanced Raman scattering (SERS) presents a sensitive, multiplexed, and rapid method that has gained attraction with recent studies showing promising results from patient samples for the multiplex detection of cancer sEVs. Various label-based SERS multiplex assays have been developed in the field of SERS including bead assays, lateral flow immunoassays, microfluidic devices, and artificial intelligence (AI) label-free SERS chips, targeting multiple surface proteins to ensure comprehensive multiplex diagnostics. These assays hold promise for enabling early detection, quantification, and subtyping of cancer-derived sEVs for cancer diagnostic applications. This review aims to provide a summary of the recent advances in the field of SERS multiplex assays for detection, quantification, and subtyping of sEVs to facilitate cancer diagnosis. This review further provides unique insights into the use of sEVs as a biomarker and aims to address the issues surrounding their translation from lab to clinic.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"9 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142788438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chitosan-modified polymeric nanoparticles for the nose-to-brain drug delivery of paroxetine: an in vitro and in vivo evaluation

IF 6.7 3区材料科学

Nanoscale Pub Date : 2024-12-06 DOI: 10.1039/d4nr04250f

Surbhi Sharma, Pammi Gauba, Amit Tyagi, Shweta Dang

{"title":"Chitosan-modified polymeric nanoparticles for the nose-to-brain drug delivery of paroxetine: an in vitro and in vivo evaluation","authors":"Surbhi Sharma, Pammi Gauba, Amit Tyagi, Shweta Dang","doi":"10.1039/d4nr04250f","DOIUrl":"https://doi.org/10.1039/d4nr04250f","url":null,"abstract":"This work focuses on the development of PLGA nanoparticles and their surface modification by chitosan to enhance the mucoadhesive properties and colloidal stability for intranasal delivery. Chitosan-coated paroxetine-loaded PLGA nanoparticles (PAR–CS–PLGA-NPs) were developed and characterized along with in vitro and in vivo evaluation. Particle size of 181.8 nm with a zeta potential of 36.3 mV was obtained. Entrapment efficiency % and drug loading % were 87.5% and 13.4%, respectively. TEM, FTIR, and DSC were also performed. In vitro drug release studies were conducted in phosphate buffered saline (pH 7.4) and simulated nasal fluid (pH 5.5), and sustained release was found until 72 h. Cellular assays on mammalian cells depicted the cell viability to be >60% even at the maximum concentration of PAR–CS–PLGA-NPs and showed significantly higher uptake than PLGA-NPs. Histopathological studies on the nasal epithelium showed no damage or inflammation when treated with PAR–CS–PLGA-NPs. In vivo studies were performed using Swiss albino mice to estimate the drug biodistribution after intranasal delivery of PAR–CS–PLGA-NPs. A significantly increased drug concentration was observed in the mouse brains (p < 0.05). Pharmacodynamics studies of the PAR–CS–PLGA-NPs were carried out by forced swimming test and locomotor activity test, demonstrating improved behavioral analysis parameters (p < 0.05). Thus, intranasal delivery of paroxetine-loaded mucoadhesive chitosan-coated PLGA nanoparticles could be potentially used for the treatment of depression.","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":"111 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0