Nanoscale最新文献

{"title":"A self-assembled monolayer regulates solid electrolyte interphase formation in anode-free lithium metal batteries.","authors":"Naufal Hanif Hawari, Shuen Tso, Man-Fai Ng, Mingsheng Zhang, Qiang Zhu, Afriyanti Sumboja, Ning Ding","doi":"10.1039/d6nr02668k","DOIUrl":"https://doi.org/10.1039/d6nr02668k","url":null,"abstract":"<p><p>Controlling solid electrolyte interphase (SEI) formation is critical for anode-free lithium-metal batteries (AFLMBs). However, plain copper (Cu) current collectors fail to form a reliable SEI during long Li plating and stripping cycles. Here, we demonstrate that a self-assembled monolayer (SAM) on Cu can direct SEI chemistry by simultaneously modulating the electrolyte accessibility and interfacial electronic structure. We investigated carboxylate-terminated SAMs of varying chain length, specifically thioglycolic acid (TGA) and mercaptoundecanoic acid (MUA), as modifiers for copper foil. The polar carboxylate terminal group enhances the accessibility of electrolytes to the Cu surface, with TGA-modified Cu (TGA@Cu) showing complete wetting by a carbonate electrolyte solution. Density functional theory shows that the TGA and PF₆^- interaction lowers the anion's lowest unoccupied molecular orbital energy from -0.02 to -0.73 eV for Cu and TGA@Cu, respectively. This shift facilitates the anion decomposition, leading to an SEI enriched with LiF and Li₂O. When paired with an NMC622 cathode, the TGA@Cu enhances the full-cell AFLMB performance, achieving 82% capacity retention over 30 cycles, compared to 55% with a plain Cu current collector. This work shows that SEI formation can be tuned by tuning the molecular-level electronic structure and interfacial accessibility, providing guidance for current collector interfacial design for AFLMBs.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure-directed synthesis of Cr₂O₃/WO₃·0.33H₂O adsorbents for rapid removal of cationic pollutants.","authors":"Xu Dong, Yiren Lu, Xide Chang, Xianhua Liu, Jiaxin Zhu, Lian Yi","doi":"10.1039/d6nr02646j","DOIUrl":"10.1039/d6nr02646j","url":null,"abstract":"<p><p>Structural modulation is essential to advance adsorption performance. Herein, amorphous Cr₂O₃-modified crystalline WO₃·0.33H₂O composites were fabricated <i>via</i> a hydrothermal-heating route using chromium acetate as a structure-directing agent. Adjusting the Cr/W precursor molar ratio tailors the material microstructure, which evolves from nanorod microspheres to nanofibrous networks and granular particles. The incorporated Cr³⁺ modulates lattice growth and surface roughness owing to its ionic compatibility with W, yielding an optimized hierarchical mesoporous network with a high specific surface area of 192.61 m² g^-1. The optimized composite exhibits efficient methylene blue adsorption, achieving 87.2% removal within 10 min and 99.9% removal within 1 h, with a maximum adsorption capacity of 92.54 mg g^-1. It also exhibits excellent selectivity toward various cationic dyes and rapidly separates anionic methyl orange from binary and quaternary mixed dye solutions within 1 min. The adsorption behavior follows pseudo-second-order kinetics and the Langmuir isotherm and is primarily governed by physical adsorption. The material's selective adsorption originates from surface electrostatic interactions, while abundant surface hydrogen bonding further enhances adsorption capacity. This work provides a feasible strategy for microstructure and interfacial engineering of WO₃-based composites toward rapid and selective removal of cationic pollutants.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":"20885-20898"},"PeriodicalIF":5.2,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Engineering upconversion nanoparticles for synergistic photodynamic, photothermal and chemotherapy.","authors":"Chenkun Gao, Bingrui Li, Hang Shangguan, Yan Zhou, Zechen Bai, Hairegu Tuxun, Bo Zhou","doi":"10.1039/d6nr02762h","DOIUrl":"https://doi.org/10.1039/d6nr02762h","url":null,"abstract":"<p><p>Cancer remains a significant threat to human health, and photodynamic therapy (PDT) is recognized as a clinically effective therapeutic strategy for tumor treatment owing to its high spatiotemporal control and minimal invasiveness. However, its application is constrained by critical limitations of conventional photosensitizers (PSs), such as narrow excitation wavelength ranges and limited tissue penetration depths. Recently, upconversion nanoparticles (UCNPs) have emerged as a promising strategy to overcome these limitations due to their distinctive near-infrared (NIR) to visible upconverting properties. In particular, the synergistic interaction between UCNPs and PSs has substantially improved the generation efficiency of singlet oxygen (¹O₂), underscoring the therapeutic potential of PDT in managing solid tumors. In this review, we comprehensively discuss the recent advancements in UCNP-based nanoplatforms for synergistic cancer therapy, focusing on the integration of PDT with photothermal therapy (PTT) and chemotherapy. We systematically examined the critical optimization strategies-from rational synthesis and surface functionalization for enhanced biocompatibility and tumor targeting to the design of intelligent nanocarriers for controlled drug release. We also discuss the current challenges facing their clinical translation and highlight prospects in developing integrated theranostic agents for personalized medicine. This review elucidates how these multimodal systems overcome the limitations of monotherapy and would greatly contribute to the research of synergistic photodynamic, photothermal and chemotherapy in the future.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graphene oxide-regulated nanoscale construction of SnO₂/N-doped carbon/rGO composite anodes from a tin naphthalocyanine precursor for lithium storage.","authors":"Lingjie Jin, Weiqiang Kong, Xiaolei Zhang, Qiwei Tang, Zhigang Wang, Junzhi Ma, Dongjun Lv","doi":"10.1039/d6nr02759h","DOIUrl":"https://doi.org/10.1039/d6nr02759h","url":null,"abstract":"<p><p>Designing nanoscale composite architectures that integrate conversion/alloying-type oxide nanocrystals with conductive carbon frameworks is an effective strategy for improving the lithium-storage behavior of high-capacity anodes. Herein, we develop a coupled molecular precursor/GO-regulated nanoscale construction strategy for SnO₂/N-doped carbon/reduced graphene oxide composite anodes. Specifically, <i>tert</i>-butyl-substituted tin naphthalocyanine (<i>t</i>BuSnNc) is employed as a molecular precursor and combined with GO to construct a SnO₂/N-doped carbon/reduced graphene oxide composite anode (<i>t</i>BuSnNc/GO-C) <i>via</i> thermal conversion. In this design, <i>t</i>BuSnNc enables the <i>in situ</i> formation of SnO₂ active species within an N-doped carbonaceous matrix, while GO-derived rGO acts as a structural regulator to promote an open wrinkled sheet-like framework with hierarchical porosity and improved active-site accessibility. Benefiting from this coupled precursor/structure design, <i>t</i>BuSnNc/GO-C delivers a reversible capacity of 926.4 mAh g^-1 after 200 cycles at 0.1 A g^-1 and retains 511.1 mAh g^-1 at 1 A g^-1, outperforming the GO-free counterpart. Kinetic analyses indicate lower charge-transfer resistance, higher apparent Li⁺ diffusion coefficients under identical testing and calculation conditions, and a slightly enhanced surface-controlled response, with the capacitive contribution reaching 92.83% at 2.0 mV s^-1. Moreover, a prelithiated <i>t</i>BuSnNc/GO-C//LiFePO₄ full cell delivers a stable reversible capacity of approximately 143 mAh g^-1 over 50 cycles, suggesting preliminary compatibility of the composite anode in a full-cell configuration. This work demonstrates a GO-regulated nanoscale construction strategy based on molecular precursor conversion, providing a design route for improving the lithium-storage behavior of SnO₂-based nanocomposite anodes.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149133984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unipolar gate field enhanced photoresponse in organic layered halide perovskites.","authors":"Apurva Yadav, Shobhit Rastogi, Ashutosh Joshi, Rupali Srivastava, Krishna Balasubramanian","doi":"10.1039/d6nr02322c","DOIUrl":"https://doi.org/10.1039/d6nr02322c","url":null,"abstract":"<p><p>Layered organic halide perovskites exhibit better chemical and structural stability than its bulk counterparts. Strong exciton binding also promotes excellent light-matter interaction with the possibility to tune the emission position using halide atom interchange. Despite excellent physical properties, the reported light sensitivity is lower than those of other material systems, largely ascribed to poor in-plane carrier transport and efficient recombination processes. Here, we show that large area CVD grown layered PEA₂PbI₄ can show an enhanced photoresponse with strong exciton resonance enhancement. The device exhibits gate-field sensitivity with a 1.5-fold enhancement at negative gate fields achieving a responsivity of 0.52 mA W^-1 at the exciton position (520 nm). These results show that the layered perovskite with simple large area deposition shows excellent promise in optoelectronic device applications.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149101196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent modernization in g-C₃N₄/MoS₂ derived heterojunctions for photocatalytic applications.","authors":"T U Umadevi, Bhagyalakshmi Balan, Smitha Knox L, Suresh Mathew","doi":"10.1039/d6nr02198k","DOIUrl":"10.1039/d6nr02198k","url":null,"abstract":"<p><p>Photocatalysis using semiconductors is a key approach for directly utilizing, transforming, and storing renewable solar energy and it has important implications for environmental applications. g-C₃N₄ is a prominent semiconductor photocatalyst with advantageous structural, electrical, optical, and chemical properties. However, it suffers from issues like high recombination rates of photogenerated charge carriers, low quantum efficiency, limited surface area and poor light absorption. These limitations can be mitigated by creating heterojunctions with complementary materials. As a transition metal dichalcogenide, MoS₂ is particularly suitable for coupling with g-C₃N₄ because of its compatible band alignment and efficient interfacial charge transfer characteristics which promote charge separation and enhance photoredox activity. This review examines recent advances and applications of the promising g-C₃N₄/MoS₂ heterojunction. The band structures, heterojunction formation and interfacial charge-transfer processes under light irradiation revealed by DFT studies of g-C₃N₄/MoS₂ heterojunctions, are systematically discussed. It critically summarizes advances in diverse design strategies and highlights the importance of constructing hierarchical g-C₃N₄/MoS₂-based heterojunctions integrated with carbonaceous materials, noble metals, metal oxides, polymers, and MOFs to enhance photocatalytic performance. The mechanistic pathways proposed for different heterostructure configurations, including Type-II, Z-scheme and S-scheme systems, are examined in detail with emphasis on their band alignment and charge-transfer characteristics. Subsequently the more exciting photocatalytic applications of g-C₃N₄/MoS₂ based heterojunctions including hydrogen generation, organic and inorganic pollutant degradation, CO₂ reduction and N₂ fixation are addressed in detail. Finally, this comprehensive review concludes with a summary of the key advances and future research directions in g-C₃N₄/MoS₂ based photocatalysts, highlighting emerging research opportunities toward their long-term practical applications.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149101187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanomatrix engineering for LDI-MS based biomedical metabolomics.","authors":"Yi Gu, Yanxi Yang, Jiao Wu, Kun Qian","doi":"10.1039/d6nr02874h","DOIUrl":"https://doi.org/10.1039/d6nr02874h","url":null,"abstract":"<p><p>Metabolomics provides functional molecular readouts of disease phenotypes, therapeutic responses, and tissue microenvironments, but its extension to low-volume, single-cell, and spatially resolved samples remains analytically challenging. Laser desorption/ionization mass spectrometry (LDI-MS) offers a rapid, direct, and high-throughput route for small-molecule analysis. However, its performance in biomedical metabolomics is largely governed by the matrix-analyte interface. Nanomaterials have emerged as attractive LDI-MS matrices because of their low background in the low-mass region, large surface area, tunable photothermal and electronic properties, and designable surface chemistry. In this review, we summarize recent advances in nanomatrix-assisted LDI-MS for biomedical metabolomics, emphasizing design principles. We discuss three key design dimensions of nanomatrix and interface engineering: structural engineering for energy absorption and desorption efficiency, surface functionalization for metabolite enrichment and low-interference ionization, and interface engineering for reproducibility, throughput, and low-volume sample compatibility. Representative biomedical applications are highlighted, including biofluid metabolic fingerprinting, extracellular vesicle and single-cell metabolomics, and spatial metabolic imaging. Finally, we discuss current challenges in matrix reproducibility, metabolite coverage, workflow standardization, and clinical validation, and outline future opportunities for integrated nanomatrix platforms in multiscale biomedical metabolomics.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149101206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Co-delivery of doxorubicin and siRNA using octreotide-conjugated gold nanorods for targeted neuroendocrine cancer therapy.","authors":"Yuling Xiao, Renata Jaskula-Sztul, Alireza Javadi, Wenjin Xu, Jacob Eide, Ajitha Dammalapati, Muthusamy Kunnimalaiyaan, Herbert Chen, Shaoqin Gong","doi":"10.1039/d6nr90176j","DOIUrl":"10.1039/d6nr90176j","url":null,"abstract":"<p><p>Correction for 'Co-delivery of doxorubicin and siRNA using octreotide-conjugated gold nanorods for targeted neuroendocrine cancer therapy' by Yuling Xiao <i>et al.</i>, <i>Nanoscale</i>, 2012, <b>4</b>, 7185-7193, https://doi.org/10.1039/C2NR31853A.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149101135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-performance thermally stable lithium metal batteries using bacterial cellulose/poly(<i>p</i>-phenylene benzobisoxazole) nanocomposite separators with interconnected nanofibrous architecture.","authors":"Aojie Zhang, Tongfei Duan, Zheng Zhang, Zhiyuan Xiong, Jin Long, Chenbin Xia, Huiyong Li","doi":"10.1039/d6nr02038k","DOIUrl":"https://doi.org/10.1039/d6nr02038k","url":null,"abstract":"<p><p>The thermal shrinkage and material deterioration of commercial polyolefin separators at high temperatures remain substantial barriers to safe lithium metal battery operation. In this work, bacterial cellulose (BC) nanofibers were employed as a matrix, with poly(<i>p</i>-phenylene benzobisoxazole) (PBO) nanofibers (PNFs) prepared <i>via</i> a reported protonation strategy. BC/PNF (BP) nanocomposite separators were fabricated <i>via</i> vacuum filtration. By incorporating 10 wt% PNFs, the BP10 separator retained an intact nanofibrous network and full dimensional stability after thermal treatment at 300 °C for 0.5 h, outperforming commercial PP in structural integrity. BP10 exhibited an ionic conductivity of 0.68 mS·cm^-1 and a lithium-ion transference number of 0.37, both exceeding those of PP. The Li/LiFePO₄ cells assembled with BP10 achieved 122.6 mAh·g^-1 after 200 cycles at 1C, and Li/Li symmetric cells sustained stable cycling for over 1000 h at 1.0 mA cm^-2; elevated-temperature cycling at 55 °C likewise outperformed PP. TG-FTIR analysis showed that PNFs shifted the thermal decomposition pathways of the nanocomposite separator, suppressing small-molecule volatile release such as CO and reducing total volatile products by ∼50%. The findings demonstrated a simple, fast and effective strategy for constructing nanocomposite separators from renewable BC and thermally robust PNFs for high-performance lithium metal battery separators with enhanced ionic transport and thermal stability.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149101162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Light-driven activation of metallic nanostructures in cancer therapy: from phototherapy to bioorthogonal catalysis.","authors":"Fatima Escudero-Amate, Jose I Garcia-Peiro, Jose L Hueso","doi":"10.1039/d6nr02243j","DOIUrl":"https://doi.org/10.1039/d6nr02243j","url":null,"abstract":"<p><p>Metallic nanostructures are versatile platforms for Nanomedicine due to their optical and catalytic properties. Their strong light absorption and efficient photothermal conversion have enabled photothermal therapy (PTT) to ablate tumors within the biologically transparent near-infrared windows. Recent advances in plasmonic engineering extend their role beyond heat generation, revealing their capacity to mediate photocatalytic transformations under physiologically relevant conditions. This dual modality enables the use of Au, Pt, Pd, and Ag, as well as less conventional Ru and Rh systems for applications spanning tumor microenvironment (TME) modulation to bioorthogonal prodrug activation. Strategies employing anisotropic nanostructures, metal-semiconductor hybrids and nanozyme cascades demonstrate that light can alleviate hypoxia, modulate metabolic pathways and achieve spatiotemporally controlled drug release. These advances suggest that photoactive metallic nanostructures can move beyond conventional PTT toward programmable, light-addressable cancer therapies.</p>","PeriodicalId":92,"journal":{"name":"Nanoscale","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149101159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}