British medical bulletin最新文献_第9页

The use of long head biceps tendon autograft for massive rotator cuff tears: a PRISMA compliant systematic review. 自体长头二头肌腱移植治疗肩袖大面积撕裂：符合PRISMA的系统综述。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-12-12 DOI: 10.1093/bmb/ldac021

Rocco Aicale, Nicola Poeta, Eugenio Savarese, Giulio Bernardini, Francesco Oliva, Nicola Maffulli

{"title":"The use of long head biceps tendon autograft for massive rotator cuff tears: a PRISMA compliant systematic review.","authors":"Rocco Aicale, Nicola Poeta, Eugenio Savarese, Giulio Bernardini, Francesco Oliva, Nicola Maffulli","doi":"10.1093/bmb/ldac021","DOIUrl":"10.1093/bmb/ldac021","url":null,"abstract":"Introduction: Rotator cuff tears (RCT) are a common cause of shoulder pain and disability, with massive RCT accounting for 10-40% of all rotator cuff tears.Sources of data: A systematic search of PubMed and Scopus electronic databases was performed up to August 2022, and a total of 17 scientific articles were included in the present PRISMA compliant systematic review.Areas of agreement: Understanding the geometric patterns in RCT is essential to achieve appropriate repositioning of the injured tendons in their anatomic location. The long head of the biceps tendon (LHBT) is usually exposed when defects of the anterolateral corner are present and can be easily used to augment rotator cuff repairs.Areas of controversy: There are no definite guideline regarding the management of massive rotator cuff tears.Growing points: The use of LHBT graft is safe and effective, but technically demanding. All studies were level IV articles of medium to high quality.Areas timely for developing research: Prospective long term follow-up studies and randomized controlled trials are needed, adding imaging evaluation and appropriate clinical outcome measures at follow-up.","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"144 1","pages":"76-89"},"PeriodicalIF":6.7,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10409590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Corrigendum to: MicroRNA in osteoarthritis: physiopathology, diagnosis and therapeutic challenge. Corrigendum to：骨关节炎中的微RNA：生理病理、诊断和治疗挑战。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-12-12 DOI: 10.1093/bmb/ldz021

Antonio Oliviero, Giovanna Della Porta, Giuseppe M Peretti, Nicola Maffulli

引用次数: 3

COVID-19 and the heart. COVID-19和心脏。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-12-12 DOI: 10.1093/bmb/ldac022

Roman Roy, Benedict McDonaugh, Kevin O'Gallagher

引用次数: 2

Late offspring effects of antenatal thyroid screening. 产前甲状腺筛查对后代的影响。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-09-22 DOI: 10.1093/bmb/ldac018

Grigorios Panagiotou, Peter N Taylor, D Aled Rees, Onyebuchi E Okosieme

{"title":"Late offspring effects of antenatal thyroid screening.","authors":"Grigorios Panagiotou, Peter N Taylor, D Aled Rees, Onyebuchi E Okosieme","doi":"10.1093/bmb/ldac018","DOIUrl":"https://doi.org/10.1093/bmb/ldac018","url":null,"abstract":"Background: Thyroid dysfunction in pregnancy is associated with adverse offspring outcomes and recent birth-cohort studies suggest that even mild degrees of thyroid dysfunction may be linked with a range of late cognitive and behavioural effects in childhood and adolescence.Sources of data: This review summarizes recent literature of observational studies and critically appraises randomized controlled trials (RCTs) of antenatal thyroid screening and Levothyroxine intervention.Areas of agreement: Overt hypothyroidism and hyperthyroidism carry significant risks for unfavourable offspring outcomes and should be appropriately corrected in pregnancy.Areas of controversy: The significance of subclinical hypothyroidism and hypothyroxinaemia is still unclear. Meta-analyses of birth-cohort studies show associations of maternal subclinical hypothyroidism and hypothyroxinaemia with intellectual deficits, attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders, while hyperthyroidism and high-normal FT4 were linked with ADHD. RCTs have shown no benefits of screening on neurodevelopmental outcomes although Levothyroxine could have been initiated too late in pregnancy in these trials.Growing points: A small number of studies have shown inconsistent associations of maternal thyroid dysfunction with offspring cardiometabolic indices including blood pressure and body weight. Correction of maternal thyroid dysfunction was, however, associated with favourable long-term metabolic profiles in mothers, including lipid profiles, fat mass and body mass index. Antenatal thyroid screening may therefore present opportunities for optimizing a wider range of outcomes than envisaged.Areas for developing research: Future trials with early antenatal thyroid screening and intervention are necessary to clarify the impact of screening on late offspring and maternal effects.","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":" ","pages":"16-29"},"PeriodicalIF":6.7,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40531492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Call for emergency action to limit global temperature increases, restore biodiversity, and protect health. 呼吁采取紧急行动，限制全球气温上升，恢复生物多样性，保护健康。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-09-22 DOI: 10.1093/bmb/ldab020

Lukoye Atwoli, Abdullah H Baqui, Thomas Benfield, Raffaella Bosurgi, Fiona Godlee, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Carlos Augusto Monteiro, Ian Norman, Kirsten Patrick, Nigel Praities, Marcel G M Olde Rikkert, Eric J Rubin, Peush Sahni, Richard Smith, Nick Talley, Sue Turale, Damián Vázquez

{"title":"Call for emergency action to limit global temperature increases, restore biodiversity, and protect health.","authors":"Lukoye Atwoli, Abdullah H Baqui, Thomas Benfield, Raffaella Bosurgi, Fiona Godlee, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Carlos Augusto Monteiro, Ian Norman, Kirsten Patrick, Nigel Praities, Marcel G M Olde Rikkert, Eric J Rubin, Peush Sahni, Richard Smith, Nick Talley, Sue Turale, Damián Vázquez","doi":"10.1093/bmb/ldab020","DOIUrl":"https://doi.org/10.1093/bmb/ldab020","url":null,"abstract":"Editor in Chief, East African Medical Journal; Editor in Chief, Journal of Health, Population and Nutrition; Editor in Chief, Danish Medical Journal; Editor in Chief, PLOS Medicine; Editor in Chief, The BMJ; Editor in Chief, British Dental Journal; Editor in Chief, The Lancet; Senior Adviser, UK Health Alliance on Climate Change; Editor in Chief, Revista de Saúde Pública; Editor in Chief, International Journal of Nursing Studies; Interim Editor in Chief, CMAJ; Executive Editor, Pharmaceutical Journal; Editor in Chief, Dutch Journal of Medicine; Editor in Chief, NEJM; Editor in Chief, National Medical Journal of India; Chair, UK Health Alliance on Climate Change; Editor in Chief, Medical Journal of Australia; Editor in Chief, International Nursing Review; and Editor in Chief, Pan American Journal of Public Health","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"143 1","pages":"30-34"},"PeriodicalIF":6.7,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39404992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antiresorptive treatments for corticosteroid-induced osteoporosis: a Bayesian network meta-analysis. 抗吸收治疗皮质类固醇所致骨质疏松症：贝叶斯网络荟萃分析。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-09-22 DOI: 10.1093/bmb/ldac017

Filippo Migliorini, Giorgia Colarossi, Jörg Eschweiler, Francesco Oliva, Arne Driessen, Nicola Maffulli

{"title":"Antiresorptive treatments for corticosteroid-induced osteoporosis: a Bayesian network meta-analysis.","authors":"Filippo Migliorini, Giorgia Colarossi, Jörg Eschweiler, Francesco Oliva, Arne Driessen, Nicola Maffulli","doi":"10.1093/bmb/ldac017","DOIUrl":"10.1093/bmb/ldac017","url":null,"abstract":"Introduction: Corticosteroid-induced osteoporosis (CIO) is the most common type of secondary osteoporosis, leading to fractures, and increased morbidity and mortality.Source of data: Pubmed, EMBASE, Scopus and Google Scholar databases.Areas of agreement: Prolonged glucocorticoids administration leads to secondary osteoporosis.Areas of controversy: The optimal management for CIO is controversial.Growing points: The present study compared bone mineral density, fractures and adverse events in patients undergoing treatment with risedronate, alendronate, zoledronate, denosumab or etidronate for CIO.Areas timely for developing research: For selected patients with CIO, alendronate performed better overall. These results must be interpreted within the limitations of the present study.Level of evidence: I, Bayesian network meta-analysis of randomized clinical trials.","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"100 1","pages":"46-56"},"PeriodicalIF":6.7,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60843136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

British medical bulletin article: resourcing of palliative and end of life care in the UK during the Covid-19 pandemic. 英国医学公报文章:2019冠状病毒病大流行期间英国姑息治疗和临终关怀的资源。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-07-09 DOI: 10.1093/bmb/ldac013

Mark Jackson

{"title":"British medical bulletin article: resourcing of palliative and end of life care in the UK during the Covid-19 pandemic.","authors":"Mark Jackson","doi":"10.1093/bmb/ldac013","DOIUrl":"https://doi.org/10.1093/bmb/ldac013","url":null,"abstract":"Introduction: Covid-19 led to a sustained increase in deaths in all four United Kingdom nations, placing strain on the UK's palliative and end-of-life care sector and raising concerns about the long-term sustainability of the sector's funding and resourcing model in the face of rising demand for these services in the coming decades.Sources of data: Published research, Marie Curie, King's College London Cicely Saunders Institute, Hull York Medical School, University of Hull, University of Cambridge, National Statistics, PubMed, DOI.Areas of agreement: Care for people at the end of their lives is a core part of the UK's health and care system with demand set to increase significantly as the UK's population ages.Areas of controversy: The UK's funding model for palliative and end-of-life care, with most care delivered by charitable sector providers and reliant on charitable donations, may be unsustainable in the face of increasing demand.Growing points: The Covid-19 pandemic led to rapid service innovation in palliative and end-of-life care, and providers should assess which of and how these innovations can be retained after the pandemic.Areas timely for developing research: Although there has been a rapid growth in knowledge during Covid-19, gaps still remain including: the reasons underlying shifts to deaths at home and the implications for family carers; the education needs of the wider healthcare workforce in palliative care; the impact of specialist palliative care services on the wider health system, including hospital admissions and place of death; and inequalities in the experiences of dying, death and bereavement during Covid-19 among groups such as those from lower socioeconomic groups and BAME communities.","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":" ","pages":"44-51"},"PeriodicalIF":6.7,"publicationDate":"2022-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40575255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Efficacy and safety of drugs used for 'assisted dying'. 用于“协助死亡”的药物的有效性和安全性。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-07-09 DOI: 10.1093/bmb/ldac009

Ana Worthington,Ilora Finlay,Claud Regnard

{"title":"Efficacy and safety of drugs used for 'assisted dying'.","authors":"Ana Worthington,Ilora Finlay,Claud Regnard","doi":"10.1093/bmb/ldac009","DOIUrl":"https://doi.org/10.1093/bmb/ldac009","url":null,"abstract":"BACKGROUND'Assisted dying' is practiced in some European countries and US states. Legislation suggests that there exists an easily prescribed drug which consistently brings about death quickly and painlessly. Evidence from jurisdictions where 'assisted dying' is practiced, however, reveals that hastening patient death is not so simple.SOURCES OF DATAThis report is a collation of assisted suicide and euthanasia drug protocols published by the Canadian Association of MAiD Assessors and Providers and the Royal Dutch Medical Association, annual data reports from the USA and Canada and relevant academic publications pertaining to methods of 'assisted dying' in the USA, Belgium, Canada and Switzerland.AREAS OF AGREEMENTA wide variety of lethal drug combinations are used for people who want their life ended, and the prevalence of complications and failures in intentionally ending life suggest that 'assisted dying' applicants are at risk of distressing deaths.AREAS OF CONTROVERSYThe efficacy and safety of 'assisted dying' drugs are currently difficult to assess, as clinician reporting is often very low.GROWING POINTSThe findings from this report reveal that little attention has been given to the problem of unmonitored prescribing and administering of lethal drug combinations, whose mode of action is unclear.AREAS TIMELY FOR DEVELOPING RESEARCHIn order to properly assess the efficacy and safety of 'assisted dying', a more thorough means of data collection regarding the drugs used must be implemented and research is urgently needed into their mode of action.","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"71 9","pages":"15-22"},"PeriodicalIF":6.7,"publicationDate":"2022-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138508252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Tackling organ donation among minority ethnic communities in the UK-a whole systems approach. 处理英国少数民族社区的器官捐赠——一个完整的系统方法。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-07-09 DOI: 10.1093/bmb/ldac008

Gurch Randhawa,Dale Gardiner

{"title":"Tackling organ donation among minority ethnic communities in the UK-a whole systems approach.","authors":"Gurch Randhawa,Dale Gardiner","doi":"10.1093/bmb/ldac008","DOIUrl":"https://doi.org/10.1093/bmb/ldac008","url":null,"abstract":"INTRODUCTIONThere are inequalities experienced by minority ethnic groups in the UK in organ donation and transplant services, with significant variation in relation to demand for, access to and waiting times for these services.SOURCES OF DATAA narrative review of research obtained via several databases, including PubMed and Medline, was conducted.AREAS OF AGREEMENTA vision of equity and inclusion, which meets the need of the heterogeneous UK population, can only be realized by adopting a culturally competent approach to systems-wide working in organ donation in four core areas-transplant services; workforce and staff training; diversity and inclusion research; and public engagement.AREAS OF CONTROVERSYMost of the data on the background of organ donors and recipients use general categories such as Asian or Black. We need to progress to a position of more granular data by more specific ethnicity so that we can better understand the trends and target action accordingly.GROWING POINTSBy positively embracing the heterogeneity of the UK population, demand for transplantation can be reduced through a sustained commitment to public health interventions and culturally competent approaches in the management of long-term conditions.AREAS TIMELY FOR DEVELOPING RESEARCHImproved access to transplantation and reduced waiting times can be achieved to increase the number of organ donors from minority ethnic groups if there are concerted and adequately resourced culturally competent interventions with concomitant evaluation programmes.","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"9 1","pages":"4-14"},"PeriodicalIF":6.7,"publicationDate":"2022-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138531675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Hamstring, bone-patellar tendon-bone, quadriceps and peroneus longus tendon autografts for primary isolated posterior cruciate ligament reconstruction: a systematic review. 腘绳肌、骨-髌肌腱-骨、股四头肌和腓骨长肌腱自体移植物用于原发性孤立后交叉韧带重建:系统回顾。

IF 6.7 2区医学

British medical bulletin Pub Date : 2022-07-09 DOI: 10.1093/bmb/ldac010

Filippo Migliorini,Andrea Pintore,Gianluca Vecchio,Francesco Oliva,Frank Hildebrand,Nicola Maffulli

{"title":"Hamstring, bone-patellar tendon-bone, quadriceps and peroneus longus tendon autografts for primary isolated posterior cruciate ligament reconstruction: a systematic review.","authors":"Filippo Migliorini,Andrea Pintore,Gianluca Vecchio,Francesco Oliva,Frank Hildebrand,Nicola Maffulli","doi":"10.1093/bmb/ldac010","DOIUrl":"https://doi.org/10.1093/bmb/ldac010","url":null,"abstract":"INTRODUCTIONSeveral autografts are available to reconstruct the posterior cruciate ligament (PCL).SOURCE OF DATACurrent scientific literature published in PubMed, Google scholar, Embase and Scopus.AREAS OF AGREEMENTHamstring, bone-patellar tendon-bone (BPTB), quadriceps and peroneus longus (PLT) are the most common tendon autografts used for primary isolated PCL reconstruction.AREAS OF CONTROVERSYThe optimal tendon source for PCL reconstruction remains nevertheless debated. Identifying the most suitable tendon autograft could assist the surgeon during primary PCL reconstruction.GROWING POINTSThe present study compared the outcome of PCL reconstruction using hamstring, BPTB, quadriceps and PLT autografts. The focus was on patient-reported outcome measures (PROMs), joint laxity, range of motion and complications.AREAS TIMELY FOR DEVELOPING RESEARCHAll autografts are viable options for PCL reconstruction, with BTB and hamstring autografts demonstrating superior PROMs. However, further clinical investigations are required to determine the ideal autograft construct.","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"70 4","pages":"23-33"},"PeriodicalIF":6.7,"publicationDate":"2022-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138508235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6