猴痘:2022 年疫情回顾。

IF 6.7 2区 医学 Q1 Medicine
Eleanor Y Lim, James Whitehorn, Lucy Rivett
{"title":"猴痘:2022 年疫情回顾。","authors":"Eleanor Y Lim, James Whitehorn, Lucy Rivett","doi":"10.1093/bmb/ldad002","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>In May 2022, the World Health Organisation declared a multi-country monkeypox outbreak in non-endemic countries following cases reported from 12 member states that were not endemic for monkeypox virus.</p><p><strong>Sources of data: </strong>Pubmed search.</p><p><strong>Areas of agreement: </strong>The virology, epidemiology, transmission, incubation and aspects of infection control are described. Clinical features of previous and current outbreaks are described, with growing observations that the current outbreak presents with clinical features distinct from previous outbreaks.</p><p><strong>Areas of controversy: </strong>There are variations in clinical presentations seen in the current outbreak that have not been seen in prior outbreaks. More research is needed to investigate the reasons for these differences.</p><p><strong>Growing points: </strong>The higher numbers of HIV-positive patients in the current outbreak has allowed better description of the disease in patients co-infected with HIV and monkeypox. The absence of more severe symptoms in HIV-positive patients in the current outbreak could possibly be due to the fact that most of these patients had well-controlled HIV, although further characterization of this cohort of patients would be useful.</p><p><strong>Areas for developing research: </strong>Current treatment and vaccination options have been extrapolated from studies of other Orthopox viruses. There remains a need for more data on the safety and efficacy of these options in the context of monkeypox infections.</p>","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"145 1","pages":"17-29"},"PeriodicalIF":6.7000,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Monkeypox: a review of the 2022 outbreak.\",\"authors\":\"Eleanor Y Lim, James Whitehorn, Lucy Rivett\",\"doi\":\"10.1093/bmb/ldad002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>In May 2022, the World Health Organisation declared a multi-country monkeypox outbreak in non-endemic countries following cases reported from 12 member states that were not endemic for monkeypox virus.</p><p><strong>Sources of data: </strong>Pubmed search.</p><p><strong>Areas of agreement: </strong>The virology, epidemiology, transmission, incubation and aspects of infection control are described. Clinical features of previous and current outbreaks are described, with growing observations that the current outbreak presents with clinical features distinct from previous outbreaks.</p><p><strong>Areas of controversy: </strong>There are variations in clinical presentations seen in the current outbreak that have not been seen in prior outbreaks. More research is needed to investigate the reasons for these differences.</p><p><strong>Growing points: </strong>The higher numbers of HIV-positive patients in the current outbreak has allowed better description of the disease in patients co-infected with HIV and monkeypox. The absence of more severe symptoms in HIV-positive patients in the current outbreak could possibly be due to the fact that most of these patients had well-controlled HIV, although further characterization of this cohort of patients would be useful.</p><p><strong>Areas for developing research: </strong>Current treatment and vaccination options have been extrapolated from studies of other Orthopox viruses. There remains a need for more data on the safety and efficacy of these options in the context of monkeypox infections.</p>\",\"PeriodicalId\":9280,\"journal\":{\"name\":\"British medical bulletin\",\"volume\":\"145 1\",\"pages\":\"17-29\"},\"PeriodicalIF\":6.7000,\"publicationDate\":\"2023-04-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British medical bulletin\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/bmb/ldad002\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British medical bulletin","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/bmb/ldad002","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 1

摘要

导言:2022年5月,世界卫生组织宣布在非猴痘流行国爆发多国猴痘疫情,此前有12个非猴痘流行国报告了病例:数据来源:Pubmed 搜索:描述了病毒学、流行病学、传播、潜伏期和感染控制的各个方面。描述了以往和当前疫情的临床特征,越来越多的观察结果表明,当前疫情的临床特征与以往疫情不同:本次疫情的临床表现与以往疫情不同。需要进行更多的研究来探究这些差异的原因:在本次疫情中,HIV 阳性患者的人数较多,这有助于更好地描述同时感染 HIV 和猴痘的患者的病情。在本次疫情中,HIV 阳性患者没有出现更严重的症状,这可能是因为大多数患者的 HIV 感染情况得到了很好的控制:目前的治疗和疫苗接种方案是根据对其他口蹄疫病毒的研究推断出来的。在猴痘感染的情况下,仍然需要更多有关这些方案的安全性和有效性的数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Monkeypox: a review of the 2022 outbreak.

Introduction: In May 2022, the World Health Organisation declared a multi-country monkeypox outbreak in non-endemic countries following cases reported from 12 member states that were not endemic for monkeypox virus.

Sources of data: Pubmed search.

Areas of agreement: The virology, epidemiology, transmission, incubation and aspects of infection control are described. Clinical features of previous and current outbreaks are described, with growing observations that the current outbreak presents with clinical features distinct from previous outbreaks.

Areas of controversy: There are variations in clinical presentations seen in the current outbreak that have not been seen in prior outbreaks. More research is needed to investigate the reasons for these differences.

Growing points: The higher numbers of HIV-positive patients in the current outbreak has allowed better description of the disease in patients co-infected with HIV and monkeypox. The absence of more severe symptoms in HIV-positive patients in the current outbreak could possibly be due to the fact that most of these patients had well-controlled HIV, although further characterization of this cohort of patients would be useful.

Areas for developing research: Current treatment and vaccination options have been extrapolated from studies of other Orthopox viruses. There remains a need for more data on the safety and efficacy of these options in the context of monkeypox infections.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
British medical bulletin
British medical bulletin 医学-医学:内科
CiteScore
13.10
自引率
1.50%
发文量
24
审稿时长
>12 weeks
期刊介绍: British Medical Bulletin is a multidisciplinary publication, which comprises high quality reviews aimed at generalist physicians, junior doctors, and medical students in both developed and developing countries. Its key aims are to provide interpretations of growing points in medicine by trusted experts in the field, and to assist practitioners in incorporating not just evidence but new conceptual ways of thinking into their practice.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信