Journal of osteoporosis and physical activity最新文献

{"title":"Brief Outline on Osteopenia","authors":"M. Prashanth","doi":"10.35248/2329-9509.20.8.227","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.227","url":null,"abstract":"","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Body Flexibility Predict Arterial Stiffening","authors":"Kenta Yamamoto, Y. Gando","doi":"10.4172/2329-9509.1000216","DOIUrl":"https://doi.org/10.4172/2329-9509.1000216","url":null,"abstract":"Arterial stiffness is a risk factor for cardiovascular disorders and mortality. Arterial stiffness increases progressively with aging. Although nobody can escape from age-related arterial stiffening, having a high-level of cardiorespiratory fitness delays age-related arterial stiffening. The primary components of physical fitness are muscular strength, cardiorespiratory fitness, and flexibility. Recent cross-sectional studies have shown that flexibility is associated with arterial stiffness, independent of muscular strength and cardiorespiratory fitness. In addition, using a 5-year longitudinal study, we found that a greater progression of age-related arterial stiffening was associated with poor flexibility in healthy adults. These cross-sectional and longitudinal studies suggest that flexibility can predict arterial stiffening. In this article, we review the recent studies regarding the relationship between arterial stiffness and flexibility.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"6 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43006177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of Some Mineral (Calcium, Phosphorous, Vitamin 25(OH) D, And Alkaline Phosphatase) in Osteoporosis Patients In Kirkuk City","authors":"N. Ali","doi":"10.4172/2329-9509.1000215","DOIUrl":"https://doi.org/10.4172/2329-9509.1000215","url":null,"abstract":"Introduction: Osteoporosis is a growing public health problem of the elderly; it’s qualified by low bone mineral density (BMD), with its associated increased risk of fractures. Despite the intensive researches, there are still large areas to explore with regard to its etiology. Method and subject: We enrolled 100 female patients (40-80 years) in this study who attended the rheumatology Unit at Azadi teaching hospital/ Kirkuk city from February 2015 to July 2016 50 patents had osteoporosis confirmed by DEXA scan and the remaining ones who are age matched were controls. We measured Vitamin D, Calcium, and Phosphorus and Alkaline phosphatase in the sera of the entire participant. A special questionnaire form was arranged and full information were collected from each subject include: name, age, sex, patients’ weight and height were measured. Result: One hundred women were enrolled in this study with mean age of (61.0 ± 10.2) years were studied; 50% of them were controls and 50% of them had osteoporosis. Age of osteoporosis group were significantly higher than control groups (56 ± 9.0) years also BMI significantly higher (p<0.001) in osteoporosis (29.1 ± 5.9) compared to the control group (28.9 ± 3.4). Both control and osteoporosis cases had calcium and phosphorus within normal range, however the difference between the levels was significantly higher in osteoporotic (8.89 ± 0.564) mg/dl than control groups (8.776 ± 0.496) mg/dl. Serum alkaline phosphatase was significantly higher in osteoporosis (96.89 ± 8.00) in comparison to the control group (81.0 ± 12.4) yet their values are still within normal range. Interestingly the vitamin D deficiency was prevalent in the study population; it was significantly much lower in the osteoporosis group compared to the control group. According to chi-square test the age significantly associated with BMD, vitamin D, and phosphor in osteoporosis groups while in the control group the age was strongly associated with BMD only. The study showed correlation between Vitamin D and Bone mineral density. Conclusion: We conclude that there was no significant association between serum Calcium, Phosphors, and alkaline phosphates with bone mineral density while show positive association between age and vitamin 25 (OH) D levels.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"6 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000215","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48378155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Young Age with Bone Mineral Density Improvement with Denosumab Treatment in Patients with Osteoporosis","authors":"S. Hayashi, K. Fukuda, T. Maeda, Yuji Hiroshima, N. Chinzei, S. Kihara, H. Nishimoto, Y. Miura, Y. Sakai, S. Hashimoto, Tomoyuki Matsumoto, K. Takayama, K. Nishida, R. Kuroda","doi":"10.4172/2329-9509.1000212","DOIUrl":"https://doi.org/10.4172/2329-9509.1000212","url":null,"abstract":"Introduction: Analysis of predictive factors for the improvement of bone mineral density (BMD) in response to osteoporosis treatment is critical. Several studies reported on the analysis of bone turnover markers as a predictive factor for the improvement of BMD; however, few studies reported on predictive factors other than bone turnover markers. Thus, this study aimed to analyze other predictive factors for distal radial BMD improvement in response to denosumab treatment among patients with osteoporosis.Methods: We evaluated 133 patients with osteoporosis over a 24 month period. All patients received denosumab (60 mg) subcutaneously every 6 months. The BMD of the distal radius was assessed in all patients and serum concentrations of PINP and TRACP5b determined.Results: Denosumab treatment resulted in a 3.3% increase, from baseline, in distal radius BMD at 24 months. The average BMD change at 24 months was not significantly changed in relation to gender or prevalent medication. The average BMD change at 24 months was negatively correlated with patient’s age. Almost all the points of PINP and TRACP5b were not correlated with BMD except TRACP5b value at 24 months.Conclusions: We found that improvement of bone mineral density with denosumab treatment for osteoporosis is associated with young age of the patients. We recommend denosumab treatment for younger patients with osteoporosis.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"6 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42170574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-Term Effects of Ovomet, Eggshell Membrane, in Joint Pain. A Double-Blind and Placebo Study","authors":"E. Gil-Quintana, M. Fenaux, M. Nuez, Andrea Molero, A. Aguirre","doi":"10.4172/2329-9509.1000211","DOIUrl":"https://doi.org/10.4172/2329-9509.1000211","url":null,"abstract":"Dietary supplements are being extensively used for the treatment of diverse joints disorders. Ovomet®, eggshell membrane, a natural source of glycosaminoglycans such as chondroitin sulfate and hyaluronic acid among other ingredients, has led to the consideration of this product as a potential treatment for joint disorders. On this basis, the aim of the present study was to evaluate the short-term effectiveness of the intake of Ovomet® in volunteers suffering from joint disorders. The double-blind and placebo study consisted on the daily intake of a capsule containing 300 mg Ovomet® or a capsule containing placebo (microcrystalline cellulose) during 30 days. The Womac questionnaire (Western Ontario and McMasters Universities Osteoarthritis Index) was employed to assess joint pain and dysfunction at days 0, 1, 3, 5, 7 and 30. Results showed a gradual and significant decrease in pain and dysfunction since day 3 on while the participant’s intaking placebo did not show changes. Similarly, there was a significant pain improvement in volunteers intaking Ovomet® compared to the placebo subjects from day 3 onwards. The daily intake of 300 mg Ovomet® showed short-term effects within the first three days in reducing significantly joint pain and dysfunction. Moreover, a significant improvement in pain was demonstrated in the Ovomet® group when comparing with placebo treatment. Ovomet® is a viable, fast, effective and safe alternative for the treatment of joint pain associated with joint disorder.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":" ","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43146602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of Subject-Specific Proximal Femur Finite Element Models Of Older Adults with Obesity to Evaluate the Effects of Weight Loss on Bone Strength.","authors":"S L Schoell,&nbsp;A A Weaver,&nbsp;D P Beavers,&nbsp;Leon Lenchik,&nbsp;A P Marsh,&nbsp;W J Rejeski,&nbsp;J D Stitzel,&nbsp;K M Beavers","doi":"10.4172/2329-9509.1000213","DOIUrl":"https://doi.org/10.4172/2329-9509.1000213","url":null,"abstract":"<p><strong>Study background: </strong>Recommendation of intentional weight loss in older adults remains controversial, due in part to the loss of bone mineral density (BMD) known to accompany weight loss. While finite element (FE) models have been used to assess bone strength, these methods have not been used to study the effects of weight loss. The purpose of this study is to develop subject-specific FE models of the proximal femur and study the effect of intentional weight loss on bone strength.</p><p><strong>Methods: </strong>Computed tomography (CT) scans of the proximal femur of 25 overweight and obese (mean BMI=29.7 ± 4.0 kg/m²), older adults (mean age=65.6 ± 4.1 years) undergoing an 18-month intentional weight loss intervention were obtained at baseline and post-intervention. Measures of volumetric BMD (vBMD) and variable cortical thickness were derived from each subject CT scan and directly mapped to baseline and post-intervention models. Subject-specific FE models were developed using morphing techniques. Bone strength was estimated through simulation of a single-limb stance and sideways fall configuration.</p><p><strong>Results: </strong>After weight loss intervention, there were significant decreases from baseline to 18 months in vBMD (total hip: -0.024 ± 0.013 g/cm³; femoral neck: -0.012 ± 0.014 g/cm³), cortical thickness (total hip: -0.044 ± 0.032 mm; femoral neck: -0.026 ± 0.039 mm), and estimated strength (stance: -0.15 ± 0.12 kN; fall: -0.04 ± 0.06 kN). Adjusting for baseline bone measures, body mass, and gender, correlations were found between weight change and change in total hip and femoral neck cortical thickness (all p<0.05). For every 1 kilogram of body mass lost cortical thickness in the total hip and femoral neck decreased by 0.003 mm and 0.004 mm, respectively. No significant correlations were present for the vBMD or strength data.</p><p><strong>Conclusion: </strong>The developed subject-specific FE models could be used to better understand the effects of intentional weight loss on bone health.</p>","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36033151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patellofemoral Pain Syndrome and Its Effect on the Walking of Affected Subjects: Update Review","authors":"Seyed Taghi Nourbakhsh, F. Bahramian, M. Arazpour, Atefeh Abutorabi, F. Mirzaee, Z. Zafarani, Hamidreza Aslani","doi":"10.4172/2329-9509.1000214","DOIUrl":"https://doi.org/10.4172/2329-9509.1000214","url":null,"abstract":"Background: Patellofemoral pain syndrome (PFPS) is complication in the knee joint that can affect the gait of affected subjects. Various studies have been done in this field. The purpose of this study is to update the review article in the effect of PFPS on gait parameters. Method: This update review includes articles published between 1990 and 2018. Our search has been done in PubMed, Google scholar, Science direct and ISI web of knowledge databases. Finally, 20 studies entered this review. Results: Subjects with PFPS show changes in walking parameters such as speed, cadence, step length and some other parameters in comparison with normal people. Conclusion: It can be concluded that some gait parameters in PFPS subjects change, and this change can be a mechanism for the reduction of patella femoral joint reaction force and pain.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"6 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000214","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70289002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demonstration of the Static Magnetic Fields Inability to Improve the Bone Mineral Density in an Osteoporotic Rat Model","authors":"Yi-Hsun Yu, Tsung-Ting Tsai","doi":"10.4172/2329-9509.1000218","DOIUrl":"https://doi.org/10.4172/2329-9509.1000218","url":null,"abstract":"Objectives: Osteoporosis is a raising public health issue. There are several medications in the treatment of osteoporosis and osteoporotic-related fractures involving either enhancement of the osteogenesis or inhibition of the osteoclastogenestis. However, each medication has side effect. Therefore, we try to look for an alternative therapy for the treatment of osteoporosis, which increases bone mineral density without accompanying side effects. Methods: In the current study, we used a Static Magnetic Field (SMF) to evaluate the hypothesis of improvement of the bone mineral density after an SMF exposure. In-vitro, we tested the capacities of osteogenesis and osteoclastogenesis on Mesenchymal Stem Cells (MSCs). In-vivo, we implanted a permanent magnet adjacent to the vertebrae in an osteoporotic rat model to examine the effects on the treatment of osteoporosis Results: In cell culture studies, a positive osteogenesis effect of Mesenchymal Stem Cells (MSCs) was observed under an SMF exposure; this osteogenesis effect was correlated to the SMF intensity. However, there was no effect on the osteoclastogenesis of MSCs under the same condition. In an osteoporotic rat model, there was no positive effect on alteration of the bone mineral density after a persistent 6-week exposure by an implanted SMF. Conclusion: An in-vitro study showed that an SMF exposure of MSCs had a positive osteogenesis effect. However, there was no effect in terms of improvement of the bone mineral density when the SMF was applied on the osteoporotic rat model.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"06 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70289042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Black Garlic Supplementation's Effect on Exercise-Induced Increase of Oxidative Stress","authors":"Lixin Wang, K. Mimura, S. Fujimoto","doi":"10.4172/2329-9509.1000217","DOIUrl":"https://doi.org/10.4172/2329-9509.1000217","url":null,"abstract":"This study investigated the effects of black garlic (BG) supplementation on exercise-induced increase of oxidative stress (EIOS) and recovery of muscle function. 20 healthy males were assigned to either a BG group (n=11, GG) or placebo group (n=9, PG), during a 14-day-study. Before and after eccentric exercise of elbow flexors, we measured muscle function, blood and urinary biochemistries. Maximal voluntary contraction strength decreased by 35% immediately post exercise in both groups. Recovery of circumference of biceps brachii in GG was significantly faster than in PG during 3-7 days post-exercise. reactive oxygen metabolites (d-ROMs) level was lower in GG than in PG during 1-3 days post-exercise, but no significant difference in anti oxidative potential (BAP) was observed between groups. Exercise induced leukocytosis and monocytes, lymphocytes and neutrophils all exhibited significant time effects. A significantly greater creatine kinase level was found on day 3 post-exercise in PG than in GG. Lipid peroxide concentration was lower during 3-7 days post exercise in GG than in PG and the 8-iso-prostaglandin F2α level was significantly greater in PG than in GG at every post-exercise point. These results suggest that BG supplementation had certain effects on suppression of EIOS and might promote the recovery of edema in injured tissue.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"6 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70289034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of the Left-Field Eye Patching on Left Spatial Neglect","authors":"Satoshi Sugimoto","doi":"10.4172/2329-9509.1000219","DOIUrl":"https://doi.org/10.4172/2329-9509.1000219","url":null,"abstract":"This report is the first study to investigate the effect of neglectedfield eye patching for a patient with hemispatial neglect. In previous studies [1-6], right-field eye patching has been reported as technique to improve left spatial neglect. This technique was based on the concept of making left space attention easier by reducing excessive rightward attention. However, a definite opinion about the effect of the right-field eye patching has not been obtained.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"06 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70289053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}