Journal of osteoporosis and physical activity最新文献

{"title":"Low Bone Mineral Density and Immunological Insights in Postmenopausal Women Affected by Primary Sjandouml;grenandrsquo;s Syndrome","authors":"S. G. Khayyat, P. Falsetti, E. Conticini, Roberto D' Aless, ro, F. Bellisai, S. Gentileschi, C. Baldi, M. Bardelli, S. Barbagli, M. Bacarelli, S. Pierguidi, Antonella Nicosia, L. Cantarini, B. Frediani","doi":"10.35248/2329-9509.20.8.229","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.229","url":null,"abstract":"Objective: Osteoporosis is the pathological reduction of bone mineral density (BMD) and the most represented metabolic skeletal disease among population. A reduction in bone mineralization levels is associated with an increased risk of frailty fractures and of healthcare costs. Although there are many evidences bridging rheumatological diseases (such Systemic Sclerosis, Lupus Erythematosus Systemics and Rheumatoid Arthritis) with bone loss, very scarce and contradictory papers evaluate bone health in primary Sjogren's syndrome (pSS). Aim of this retrospective study is to evaluate BMD in pSS and its relationship with inflammatory markers, Ro/SSA and La/SSB antibodies. Methods: Fifty-three postmenopausal pSS were matched with 93 controls and studied for BMD measured by Dual Energy X- ray absorptiometry (DXA). Anti-nuclear antibodies (ANA), anti-extractable nuclear antigens (ENA), Anti- Ro/SSA, and anti-La/SSB antibodies, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were collected too. Mean BMDs of each explored region was compared and osteoporosis’s (OP) prevalence was assessed. Pearson’s analysis and multivariate regression models were built to highlight variables interrelations. Results: BMD was lower in pSS compared to controls, both expressed as g/cm2 and T-score considering lumbar spine and femoral neck. OP prevalence was higher among pSS compared to controls. Weight acted as the best predictor of lumbar BMD in multivariate model. No difference on BMD status was found between pSS with antibodies positivity and altered inflammatory markers with subjects displaying normal sera levels of the abovementioned variables. Conclusions: pSS female patients in an early stage of disease have lower BMD compared to healthy controls. Anti- Ro/SSA and anti/La antibodies and inflammatory markers are not related with BMD.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overview of Osteomyelitis Condition","authors":"M. Prashanth","doi":"10.35248/2329-9509.20.8.230","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.230","url":null,"abstract":"","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress and Impact of JOPA on Scientific Community","authors":"F. Carranza","doi":"10.35248/2329-","DOIUrl":"https://doi.org/10.35248/2329-","url":null,"abstract":"Fanconi disorder may be a deformity of proximal tubule driving to malabsorption of different electrolytes and substances that are ordinarily retained by the proximal tubule. It could be a inherited or acquired condition. Anti-viral drugs are now a relatively common cause of Fanconi Syndrome. Nucleoside reverse transcriptase inhibitors (NRTIs) can cause PT toxicity, but it is observed more frequently with the nucleotide reverse transcriptase inhibitors (NtRTIs) adefovir, cidofovir and tenofovir, probably due to the high levels of uptake of these drugs into PT cells via organic anion transporters.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69998507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief Note on Osteoporotic Crack Management","authors":"M. Prashanth","doi":"10.35248/2329-9509.20.8.224","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.224","url":null,"abstract":"*Correspondence to: Manchala Prashanth, Department of Pharmacology, Osmania University, Telangana, India, E-mail: parrish.edu427@ gmail.com Received: July 23, 2020; Accepted: July 31, 2020; Published: August 07, 2020 Citation: Prashanth M (2020) Brief Note on Osteoporotic Crack Management. J Osteopor Phys Act. 8:224. doi: 10.35248/2329-9509.20.8.224 Copyright: ©2020 Prashanth M. This is an open access article distributed under the term of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. SHORT COMMUNICATION","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"77 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annotation on Osteosarcoma","authors":"Xiaolong Meng","doi":"10.35248/2329-9509.20.8.E117","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.E117","url":null,"abstract":"*Correspondence to:XiaolongMeng, Anderson Cancer Center, University of Texas, USA, E-mail: mxl@brigtsopt.org Received: November 13, 2020,Accepted: November 21, 2020, Published: November28, 2020 Citation:Meng X (2020) Annotation on Osteosarcoma. J Osteopor Phys Act. 8:e117. doi: 10.35248/2329-9509.20.8.e117 Copyright: © 2020 Meng X. This is an open access article distributed under the term of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. EDITORIAL","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of High Intensity Exercise during Early Postmenopause-the Randomized Controlled ACTLIFE-Study","authors":"W. Kemmler, Michael Hettchen, M. Kohl, M. Murphy, M. Shojaa, M. Ghasemikaram, L. Bragonzoni, F. Benvenuti, C. Ripamonti, G. Benedetti, M. Julin, T. Risto, S. Stengel","doi":"10.35248/2329-9509.20.8.228","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.228","url":null,"abstract":"The aim of the study was to determine the effect of a dedicated exercise program on important menopausal risk factors and complaints in osteopenic early-postmenopausal women. Fifty-four women, 1-5 years postmenopause with osteopenia were randomly assigned (a) to a high impact weight bearing/high intensity, high velocity resistance training group (EG: n=27) exercising three times a week or (b) to an attention control group (CG: n=27). Study endpoints were body composition including Bone Mineral Density (BMD) at the Lumbar Spine (LS) as determined by Dual-Energy X-Ray Absorptiometry (DXA), menopausal symptoms, low back pain, lower extremity strength and power. After 28 weeks of intervention, significant effects were determined for free fat mass (EG: 0.48±0.68 kg vs CG: -0.15±0.88 kg, standardized mean differences (SMD): 0.80, p=.005), total body fat mass (EG: -1.19±1.26 kg vs CG: 0.36±1.59 kg,SMD: 1.08, p=.001), abdominal body fat rate (-1.26±1.99% vs 0.54± 1.53%, SMD: 1.02, p=.001), low back pain frequency (SMD: 0.55, p=.049) and severity (SMS: 0.66, p=.018), lower extremity strength (SMD: 1.46, p<.001) and jumping height (SMD: 0.92, p<.001) in the EG compared with the CG. Menopausal complaints improved in both groups, but changes were only significant in the EG (SMD: 0.33, p=.232). We did not determine significant exercise effects on LS-BMD (SMD: 0.26, p=.351). In conclusion, we demonstrate the general effectiveness of a multipurpose exercise protocol on various risk factors and complaints related to the menopausal transition. Future assessments have to determine the exercise effects on BMD, possibly the most challenging physiologic outcome of this ongoing project.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on Degenerative Joint Disease (Osteoarthritis)","authors":"M. Prashanth","doi":"10.35248/2329-9509.20.8.225","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.225","url":null,"abstract":"","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70012835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overview on Osteoporosis Management","authors":"M. Prashanth","doi":"10.35248/2329-9509.20.8.226","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.226","url":null,"abstract":"Osteoporosis is one of the most common disorders around the world. Osteoporotic fracture especially hip fracture are associated with an increased mortality rate in elders. However, elders with osteoporosis or at high risk of fractures remain largely underdiagnosed and undertreated. The screening, diagnosis, and treatment of osteoporosis must be improved to maintain pace with its fast-growing prevalence. This review will cover risk factors of osteoporosis, screening and diagnosis tools, newfound advancements, current medical treatments including options for special populations of concern, and future research directions.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the Barriers and Enablers to Sporting Activity in Relation to Bone Health: A Qualitative Narrative Study among Adolescents andYoung Adults in New Zealand","authors":"Hansa S Patel, H. Denison, P. Teesdale‐Spittle, E. Dennison","doi":"10.35248/2329-9509.20.8.220","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.220","url":null,"abstract":"Background: Sports participation may be considered a method of reducing the risk of fragility fracture in later life by maximizing Peak Bone Mass (PBM) in the growing years. However, sports participation typically declines during late adolescence and adulthood. This qualitative study aims to identify barriers and facilitators to engaging with regular weight bearing sporting activity in adolescents and young adults in New Zealand. Methods: 44 adolescents and young adults aged 17 to 33 participated in nine focus groups. The study was conducted using a semi-structured approach with open-ended questions and prompts. Transcripts were thematically coded using an inductive content analysis approach. Results: The three main barriers to sports participation that emerged were a) structural (disorientation in a new living environment, facilities, access to healthcare), b) social (financial and time constraints) and c) personal (social pressures and lack of an understanding of why sporting activity matters for bone health) while enablers of sports participation included a) supportive environments, b) access to health checks including support to avoid injury and c) education to better understand benefits of recreational sporting activity. Conclusions: Current awareness of osteoporosis and lifestyle factors that impact PBM is limited. Educational interventions are now warranted and urgently required.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"8 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise Preferences for People with Osteoporosis, Identifying Barriers, Facilitators, Needs and Goals of Exercise","authors":"C. Ziebart, J. Macdermid, D. Bryant, Mike Szekeres, N. Suh, Aliya A. Khan","doi":"10.35248/2329-9509.20.8.221","DOIUrl":"https://doi.org/10.35248/2329-9509.20.8.221","url":null,"abstract":"Purpose: It is challenging for many people with osteoporosis to initiate and adhere to an exercise program. Currently there is little evidence on exercise preferences of people with osteoporosis, yet these factors may contribute to improved exercise adherence. Therefore, this project surveyed patients with osteoporosis to understand their exercise preferences, barriers, needs, and goals. Methods: The Personalized Exercise Questionnaire (PEQ) was used to gain insight into the barriers, facilitators, and goals related to exercise. Participants were recruited from a subspecialty metabolic bone disorder clinic, within the Greater Toronto Area, in Ontario, with a large population of osteoporotic patients. Data collection took place, inside the clinic, from December 2018 to June 2019 Results: Data on a total of 287 surveys were collected. The sample was 90% female with a mean age of 67 (SD: 10.7) years. Most participants preferred to exercise in the morning (n=208, 75%), on their own time (n=180, 65%), with exercise that were easy to perform (n=151, 55%), slow paced (n=133, 48%), and easy to remember (n=117, 43%).  Home (n=171, 62%) was the most preferred location to exercise. The most important goal for the participants was to improve strength (n=241, 84%) and the least important goal was to reduce falls (n=129, 45%). Time was the most common barrier reported in 30% of participants and followed by pain in 23% of the participants. Conclusion: This study provides insight into participant preferences for exercise. The major finding was between men and women were where they preferred to exercise. Men preferred to exercise at home or at the gym, and women preferred to exercise at home or outdoors.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"18 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70013127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}