Journal of osteoporosis and physical activity最新文献_第10页

High Prevalence of Sarcopenia in Women with Osteoporotic Fractures 骨质疏松性骨折患者骨骼肌减少的高发率

Journal of osteoporosis and physical activity Pub Date : 2016-08-19 DOI: 10.4172/2329-9509.1000181

Candela Fernández, B. Oliveri, A. Bagur, Dolores Gómez Glorioso, D. González, S. Mastaglia, C. Mautalen

{"title":"High Prevalence of Sarcopenia in Women with Osteoporotic Fractures","authors":"Candela Fernández, B. Oliveri, A. Bagur, Dolores Gómez Glorioso, D. González, S. Mastaglia, C. Mautalen","doi":"10.4172/2329-9509.1000181","DOIUrl":"https://doi.org/10.4172/2329-9509.1000181","url":null,"abstract":"The aim of the present study was to assess the prevalence of sarcopenia in women with osteopenia/osteoporosis with or without fragility fractures. Patients and methods: 112 ambulatory women with osteopenia/osteporosis were included. Body composition was determined by DXA. Weight, height, body mass index (BMI), bone mineral density (BMD) of the total skeleton, total lean mass (LM), appendicular lean mass (ALM) and the index: appendicular lean mass/height² (ALM/h²) were determined. Grip strength and self-selected gait speed were assessed. Results: Average (X ± SD) results were: age 70.9 ± 8.2 years, BMI: 23.1 ± 3.3 kg/h², total skeleton BMD T-Score:-1.7 ± 0.8, total LM 33.3 ± 3.8 kg, ALM 14.4 ±2.1 kg and ALM/h²: 5.86 ± 0.68 kg/h². Walking speed 0.96±0.21m/s and handgrip: 18.8 ± 4.8 kg. The prevalence of sarcopenia was: 24.7% (International Working Group criteria). Values for BMI, LM, ALM, ALM/h², gait speed and hand grip were significantly lower in sarcopenic vs. non-sarcopenic patients. 29 patients, average age: 70.5 ± 8.0 years had osteoporotic fragility fractures (Fx). The prevalence of sarcopenia in the group of patients with Fx was 41.4% vs. 19.3% in the non-Fx patients (n=83) (p<0.018). Conclusion: The prevalence of sarcopenia in women with osteopenia/osteoporosis was higher compared to that usually reported in non-selected patients of similar age. Those with bone fractures had a significantly higher prevalence of sarcopenia compared to the non-fracture patients. The assessment of muscle mass and function in patients with osteopenia/osteoporosis is recommended.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"4 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2016-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000181","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70288743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Use of Finite Element Analysis to Predict Type of Bone Fractures and Fracture Risks in Femur due to Osteoporosis 用有限元分析预测骨质疏松所致股骨骨折类型及骨折风险

Journal of osteoporosis and physical activity Pub Date : 2016-07-30 DOI: 10.4172/2329-9509.1000180

M. Reddy, B. Ganesh, K. Bharathi, P. Chittibabu

{"title":"Use of Finite Element Analysis to Predict Type of Bone Fractures and Fracture Risks in Femur due to Osteoporosis","authors":"M. Reddy, B. Ganesh, K. Bharathi, P. Chittibabu","doi":"10.4172/2329-9509.1000180","DOIUrl":"https://doi.org/10.4172/2329-9509.1000180","url":null,"abstract":"The density of minerals in bone can be measured by Bone Densitometry. The minerals in the bone are used to estimate the fracture risk due to osteoporosis in people of all age groups. Osteoporosis causes the decrease in mineral density of bone due to formation of minute holes (loss of bone) in bone. Osteoporotic fractures are a vital public health concern, early diagnosis of persons with higher risk of osteoporosis can help them free from future onset of multiple and sudden fractures in bone. This study is carried out by using Finite Element Analysis (FEA) on femur bones under static condition. Finite Element Analysis had been widely used to understand the mechanical behavior of femur bones of various age groups from the images developed by Computed Tomography (CT) Scans. In this work three dimensional models of the human femur bones were developed by using MIMICS software and Finite Element (FE) analysis was carried out by using COMSOL 5.0 Multi physics software. The results obtained were compared with WHO standards. These results indicate a correlation between bone densitometry values of various age groups and the computed stress T-score values from the models. This work can act as a new approach to find bone density, predicting the type of fractures and onset of osteoporosis in the bones.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"4 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2016-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000180","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70288675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Herbal Medicine for General and Disuse Osteoporosis 一般和废弃骨质疏松症的草药

Journal of osteoporosis and physical activity Pub Date : 2016-06-27 DOI: 10.4172/2329-9509.1000179

P. Leung

引用次数: 2

Optimal Handle Grip Span for Maximum Hand Grip Strength and Accurate Grip Control Strength Exertion according to Individual Hand Size 最佳手柄抓地力跨度最大的手抓地力和准确的抓地力控制力量发挥根据个人手的大小

Journal of osteoporosis and physical activity Pub Date : 2016-06-04 DOI: 10.4172/2329-9509.1000178

K. Liao

{"title":"Optimal Handle Grip Span for Maximum Hand Grip Strength and Accurate Grip Control Strength Exertion according to Individual Hand Size","authors":"K. Liao","doi":"10.4172/2329-9509.1000178","DOIUrl":"https://doi.org/10.4172/2329-9509.1000178","url":null,"abstract":"Background: Hand grip strength (HGS) and grip control strength (GCS) are two predictors of upper-extremity function to undertake activities of daily living. Numerous studies have indicated that hand size and handle diameter independently affect HGS. However, none has explored the effects of matching hand size to optimal grip span on ergonomic outcomes. The aim of this article was to investigate the relationships among grip strength, hand size, and grip span. \u0000Methods: Seventy two healthy adults (age range 18-30 year) were divided into three hand size groups (small 23, medium 25, and large 24) and evaluated their HGS and GCS data three times on both hands. Hand size was measured from the base of hand to the tip of middle finger and three different grip spans (47.6, 60.3, and 73.0 mm) were executed. \u0000Results: The results indicated that individual hand size was positively correlated with maximum HGS in the both hands (p 0.05). Analysis of variance demonstrated a clearly significant difference in HGS for men, not for women, in the three hand size groups. For participants in the three different hand size groups, a grip span of 47.6 mm would exert the maximum HGS. Conclusion: Hand grip strength was influenced by hand size and grip span in both hands. There is an optimal grip span to which the dynamometer should be adjusted when measuring hand grip strength in people. These findings may guide occupational therapy clinicians and staff members designing ergonomic interventions.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"4 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2016-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70288555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

In vivo Testing of a Bone-selective Fullerene: Preliminary Safety and Efficacy Testing 骨选择性富勒烯的体内试验:初步安全性和有效性试验

Journal of osteoporosis and physical activity Pub Date : 2016-05-27 DOI: 10.4172/2329-9509.1000174

C. Ambrose, I. R. G. Peralta, J. Mika, Gloria R. Gogola, E. Johnson, L. Culton, Michael J. Condron, C. Heiss, L. Wilson

引用次数: 0

Preinjury Factors that Influence the Outcome of Patients with Hip Fracture 影响髋部骨折患者预后的损伤前因素

Journal of osteoporosis and physical activity Pub Date : 2016-05-25 DOI: 10.4172/2329-9509.1000177

M. Kawamura, Y. Inaba, N. Kobayashi, Y. Yukizawa, H. Choe, T. Tezuka, So Kubota, Tomoyuki Saito

{"title":"Preinjury Factors that Influence the Outcome of Patients with Hip Fracture","authors":"M. Kawamura, Y. Inaba, N. Kobayashi, Y. Yukizawa, H. Choe, T. Tezuka, So Kubota, Tomoyuki Saito","doi":"10.4172/2329-9509.1000177","DOIUrl":"https://doi.org/10.4172/2329-9509.1000177","url":null,"abstract":"Background: The question of whether patients with hip fracture can be discharged home or require hospital transfer for additional rehabilitation is critical. The same clinical pathway is not suitable for all patients. However, there are no clear indices for establishing the appropriate clinical pathway. To address this, we examined preinjury factors, including the Barthel index (BI), and performed logistic regression analysis to identify factors affecting the outcome (direct home discharge or hospital transfer) of patients with hip fracture. \u0000Materials and methods: Patients with hip fracture who underwent surgery at Yokohama City University hospital were consecutively enrolled, and clinical data were retrospectively reviewed. Intergroup (direct home discharge or hospital transfer) comparison was performed using Student’s t test (continuous variables) and Fisher’s exact test (categorical variables). Factors affecting outcome were determined by logistic regression analysis. Receiver operating characteristic (ROC) curve analysis was used to identify the cut-off level, sensitivity, and specificity of the identified factors. \u0000Results: The preinjury BI scores for patients discharged home directly were significantly higher (p 79 were difficult to discharge directly home and were more likely to be transferred to another hospital (95.6% sensitivity and 62.9% specificity). \u0000Conclusions: Low preinjury BI scores ( 79) indicate a requirement for a co-operative pathway between regional hospitals that ensures a smooth hospital transfer.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"4 1","pages":"2-4"},"PeriodicalIF":0.0,"publicationDate":"2016-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70288496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polymorphisms in the Osteoprotegrin Gene with Risk of Osteoporosis and Urinary Calcium Level in a Chinese Population 骨蛋白素基因多态性与中国人群骨质疏松和尿钙水平的关系

Journal of osteoporosis and physical activity Pub Date : 2016-05-23 DOI: 10.4172/2329-9509.1000176

Yinghua Li, Yougen Wu, T. Lu, M. Yuan, Yunqing Cui, Yunjiao Zhou, Gong Yang, Yang Hong

{"title":"Polymorphisms in the Osteoprotegrin Gene with Risk of Osteoporosis and Urinary Calcium Level in a Chinese Population","authors":"Yinghua Li, Yougen Wu, T. Lu, M. Yuan, Yunqing Cui, Yunjiao Zhou, Gong Yang, Yang Hong","doi":"10.4172/2329-9509.1000176","DOIUrl":"https://doi.org/10.4172/2329-9509.1000176","url":null,"abstract":"Osteoporosis is an age-related disease caused by imbalanced calcium metabolism identified to be associated with genetic variations of multiple genes including osteoprotegrin (OPG). While bone mineral density (BMD) predicts the risk of osteoporotic fractures, the urinary calcium level (UCL) may reflect calcium metabolism, which thereby indicates osteoporotic trends. BMD of 1,206 local Chinese geriatrics in Shanghai was measured by dual X-ray absorptionmetry. UCL were examined in 728 fasting geriatric urine samples by photometry. Genotyping of the OPG SNPs rs1032128, rs334061 and rs3134063 in 481 subjects including healthy controls, osteopenia and osteoporosis patients was performed and the association between the OPG SNP variations and UCL was assessed among all comparative groups. Differences in age and BMD were statistically significant between males and females with either normal BMD or osteopenia, but were not between those with osteoporosis. Significant correlations were found between BMD and genotypes of rs1032128 in males, and between BMD and age in females. The genotypes of rs1032128 were significantly correlated with BMD in males, but were correlated with UCL in females. UCL was significantly correlated with BMD in males but was associated with rs1032128 genotypes in females. The AA type of rs1032128 was independently associated with risk of osteoporosis in males. The GG type of rs1032128 was negatively associated with UCL in males but was positively associated with UCL in females. Our data suggest that the genotypes of the OPG SNP rs1032128 may protect old males from osteoporosis development, and that UCL may be useful to predict osteoporosis if combined with the genotypes of the OPG SNP, at least in some local Chinese geriatrics.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"4 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2016-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000176","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70288437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Impending Importance of Physical Exercise in Maintaining Perfect Bone Health and Preventing the Onset of Osteoporosis 体育锻炼在保持骨骼健康和预防骨质疏松症发病中的重要性迫在眉睫

Journal of osteoporosis and physical activity Pub Date : 2016-04-15 DOI: 10.4172/2329-9509.1000173

M. Raviteja, apaka, S. Nellore

引用次数: 5

Frailty Screening and Pre-habilitation in Older Spine Patients – Reversing the Effects of Sedentary Life-styles to Improve Surgical Outcomes for Older Patients and Reduce Healthcare Costs 老年脊柱患者的衰弱筛查和预康复——扭转久坐生活方式的影响，改善老年患者的手术结果并降低医疗成本

Journal of osteoporosis and physical activity Pub Date : 2016-04-11 DOI: 10.4172/2329-9509.1000171

Yonge Rp, Berven Sh

引用次数: 3

Bone Loss or a Case of Mistaken Identity 骨质流失或认错人的案例

Journal of osteoporosis and physical activity Pub Date : 2016-03-28 DOI: 10.4172/2329-9509.1000172

J. Borges, Lewiecki Em, L. Pavlik

引用次数: 0