排卵期、蛋壳膜对关节疼痛的短期影响。双盲安慰剂研究

E. Gil-Quintana, M. Fenaux, M. Nuez, Andrea Molero, A. Aguirre
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引用次数: 4

摘要

膳食补充剂被广泛用于治疗各种关节疾病。Ovomet®蛋壳膜是糖胺聚糖的天然来源,如硫酸软骨素和透明质酸等成分,因此被认为是治疗关节疾病的潜在药物。在此基础上,本研究的目的是评估患有关节疾病的志愿者服用Ovomet®的短期有效性。双盲和安慰剂研究包括在30天内每天摄入含有300 mg Ovomet®的胶囊或含有安慰剂(微晶纤维素)的胶囊。采用Womac问卷(西安大略大学和麦克马斯特斯大学骨关节炎指数)评估第0、1、3、5、7和30天的关节疼痛和功能障碍。结果显示,自第3天起,疼痛和功能障碍逐渐显著减轻,而参与者服用安慰剂的情况没有变化。同样,从第3天开始,与安慰剂受试者相比,服用Ovomet®的志愿者的疼痛有显著改善。每天摄入300 mg Ovomet®在头三天内显示出显著减少关节疼痛和功能障碍的短期效果。此外,与安慰剂治疗相比,Ovomet®组的疼痛有显著改善。Ovomet®是一种可行、快速、有效和安全的替代品,可用于治疗与关节疾病相关的关节疼痛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Short-Term Effects of Ovomet, Eggshell Membrane, in Joint Pain. A Double-Blind and Placebo Study
Dietary supplements are being extensively used for the treatment of diverse joints disorders. Ovomet®, eggshell membrane, a natural source of glycosaminoglycans such as chondroitin sulfate and hyaluronic acid among other ingredients, has led to the consideration of this product as a potential treatment for joint disorders. On this basis, the aim of the present study was to evaluate the short-term effectiveness of the intake of Ovomet® in volunteers suffering from joint disorders. The double-blind and placebo study consisted on the daily intake of a capsule containing 300 mg Ovomet® or a capsule containing placebo (microcrystalline cellulose) during 30 days. The Womac questionnaire (Western Ontario and McMasters Universities Osteoarthritis Index) was employed to assess joint pain and dysfunction at days 0, 1, 3, 5, 7 and 30. Results showed a gradual and significant decrease in pain and dysfunction since day 3 on while the participant’s intaking placebo did not show changes. Similarly, there was a significant pain improvement in volunteers intaking Ovomet® compared to the placebo subjects from day 3 onwards. The daily intake of 300 mg Ovomet® showed short-term effects within the first three days in reducing significantly joint pain and dysfunction. Moreover, a significant improvement in pain was demonstrated in the Ovomet® group when comparing with placebo treatment. Ovomet® is a viable, fast, effective and safe alternative for the treatment of joint pain associated with joint disorder.
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