Journal of osteoporosis and physical activity最新文献_第7页

The Relationship between Osteoporosis and Visceral Adiposity Index in Postmenopausal Women 绝经后妇女骨质疏松与内脏脂肪指数的关系

Journal of osteoporosis and physical activity Pub Date : 2018-01-01 DOI: 10.4172/2329-9509.1000220

Halis Elmas, M. Can, I. Guney, M. Ayhan, C. Duran, I. Tolu

引用次数: 0

Effects of Different Types of Physical Training on Bone Mineral Density in Men and Women 不同类型体育锻炼对男女骨密度的影响

Journal of osteoporosis and physical activity Pub Date : 2017-08-25 DOI: 10.4172/2329-9509.1000207

H. Arazi, Ehsan Eghbali

引用次数: 7

Importance of Recognition of Osteoporosis and the Radiologic Diagnosis Using DEXA Technique DEXA技术在骨质疏松症诊断及影像学诊断中的重要性

Journal of osteoporosis and physical activity Pub Date : 2017-07-31 DOI: 10.4172/2329-9509.1000206

M. Aldosh

{"title":"Importance of Recognition of Osteoporosis and the Radiologic Diagnosis Using DEXA Technique","authors":"M. Aldosh","doi":"10.4172/2329-9509.1000206","DOIUrl":"https://doi.org/10.4172/2329-9509.1000206","url":null,"abstract":"Objective: Osteoporosis is the most common bone disease in humans; It is widely recognized as an important public health problem because of the significant morbidity, mortality and costs associated with its complications. The main objective of this study is to assess the osteoporosis disease and bone mineral density (MBD) in adults and menopausal patients and to estimate that osteoporosis can be prevented, diagnosed and treated before any fracture occur. \u0000Methods: This study was conducted in order to an intense effort to better recognition and understanding of osteoporosis disease and the importance of the medical radiologic diagnosis to preventing of osteoporotic fractures, using radiologic tools Dual energy x-ray absorptiometry (DEXA). Population of the study including male and female patient’s age 18 years and older, whom underwent (DEXA) exam in period from September 2016 to March 2017. \u0000Results: The main results a proved that osteoporosis can be prevented, diagnosed and treated before any fracture occurs by using BMD test. The prevalent of osteoporosis reach 86 out of 136 scanned patients with DEXA with percentage (63.3%) with the score-2.5 or lower. Others results achieved that the big distribution an effected by osteoporosis were found in the elder age over 50 years. The results also achieved the common risk factors associate with postmen pause with percentage of 43.0% and the common patient’s risk of fracture occur in the lumber spine by percentage of 45.4% a according to their T score. \u0000Conclusion: Although for many years there was awareness of the morbidity and mortality associated with fragility fractures, real progress only came with the ability to diagnose osteoporosis before fractures occur.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"5 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70288939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Platelet-Rich Plasma Enhanced Bone Autograft in Femoral Head Necrosis-A Case Series Report on a Six-Year Follow-Up Period 富含血小板的血浆增强自体骨移植治疗股骨头坏死——6年随访病例系列报告

Journal of osteoporosis and physical activity Pub Date : 2017-07-14 DOI: 10.4172/2329-9509.1000205

T. Lakatos, B. Major, P. Somogyi, G. Vácz, M. Simon, I. Hornyák, Z. Lacza

{"title":"Platelet-Rich Plasma Enhanced Bone Autograft in Femoral Head Necrosis-A Case Series Report on a Six-Year Follow-Up Period","authors":"T. Lakatos, B. Major, P. Somogyi, G. Vácz, M. Simon, I. Hornyák, Z. Lacza","doi":"10.4172/2329-9509.1000205","DOIUrl":"https://doi.org/10.4172/2329-9509.1000205","url":null,"abstract":"Aim: We compared the long-term results of two treatment regimes in avascular femoral head necrosis. \u0000Methods: We performed a retrospective clinical observational study on 19 hips that were operated on by core decompression and autologous bone impaction enhanced with platelet-rich plasma (platelet-rich plasma+bone autograft group). As a control, 13 hips were operated on by core decompression only (decompression group). Joint replacement was evaluated as the primary endpoint of the study, functional results were evaluated according to the Harris Hip Score and bone density measurements were performed. \u0000Results: Prosthesis implantation was significantly less frequent in the platelet-rich plasma+bone autograft group than in the decompression group (p<0.05). In the platelet-rich plasma+bone autograft group, operated hip function at follow-up declined according to advancement of the preoperative Ficat stages. No specific pattern in the bone density scoring was identified between the groups analyzed. \u0000Conclusion: The combination of platelet-rich plasma with core decompression and autologous bone impaction may be an effective method in lowering the need for hip prosthesis implantation in the treatment of femoral head avascular necrosis.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44238055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Are Orthopedic Surgeons’ Subjective Intraoperative Conclusions About Bone Mass Accurate? 骨科医生术中对骨量的主观结论准确吗？

Journal of osteoporosis and physical activity Pub Date : 2017-06-30 DOI: 10.4172/2329-9509.1000204

O. Brink

{"title":"Are Orthopedic Surgeons’ Subjective Intraoperative Conclusions About Bone Mass Accurate?","authors":"O. Brink","doi":"10.4172/2329-9509.1000204","DOIUrl":"https://doi.org/10.4172/2329-9509.1000204","url":null,"abstract":"Objective: To validate orthopedic surgeons’ subjective estimation of bone mineral density and presence of osteoporosis against the gold standard, dual x-ray absorptiometry (DXA). \u0000Methods: Orthopedic surgeons were asked immediately postoperatively to evaluate the quality of patients’ bone using a 10-cm visual analog scale (VAS) ranging from very poor to extremely high bone quality. They were also asked to conclude whether the bone was osteoporotic, or if they were unable to answer. Within 3 months postoperatively, all patients underwent DXA to measure their bone mineral density. Receiver operating characteristic (ROC) curves were used as diagnostic tools to describe the accuracy of the VAS score against the presence of osteoporosis based on DXA or the bone status category (normal, osteopenic or osteoporotic). \u0000Results: Fifty-three patients were included. Areas under the ROC curves for measuring the accuracy of the VAS were 0.73 for diagnosing abnormal bone status (osteopenia and osteoporosis, and 0.70 for diagnosing osteoporosis. When using a cutoff point of ≤ 4 cm on the VAS for diagnosing osteoporosis, the sensitivity was 85%, specificity was 42%, and 75% of patients were correctly classified. The positive predictive value of the surgeons’ conclusion of osteoporosis was 50%, and the negative predictive value was 83%. \u0000Conclusion: Orthopedic surgeons are in relation to performing surgery on fractures able to distinguish normal from abnormal bone with fair accuracy. \u0000Level of evidence: Prospective cohort study, level II.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48875949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contralateral Prophylactic Reinforcement in Case of First Low-Energy Hip Fracture: First-in-Man Clinical Data of a New Percutaneous Internal Fixation Device 对侧预防性加固治疗首次低能量髋部骨折：新型经皮内固定器的首次临床数据

Journal of osteoporosis and physical activity Pub Date : 2017-06-21 DOI: 10.4172/2329-9509.1000202

S. Marek, L. Charles, J. Mark, R. Pieter, Maas Charlene

{"title":"Contralateral Prophylactic Reinforcement in Case of First Low-Energy Hip Fracture: First-in-Man Clinical Data of a New Percutaneous Internal Fixation Device","authors":"S. Marek, L. Charles, J. Mark, R. Pieter, Maas Charlene","doi":"10.4172/2329-9509.1000202","DOIUrl":"https://doi.org/10.4172/2329-9509.1000202","url":null,"abstract":"A prevention dedicated osteosynthesis device (Y-STRUT®, Hyprevention) was developed to reinforce the proximal femur on patients with high risk of fragility hip fracture. A multicentre pilot study was initiated to evaluate the feasibility, safety and tolerance of this device and the related operative procedure. \u0000This clinical study is an on-going prospective series of 15 patients. Between February 2013 and December 2016, 10 patients were implanted. Patients were recruited when arriving to emergencies following a low-energy trauma leading to a pertrochanteric hip fracture. The device was implanted in combination with bone cement into the contralateral hip during the same anaesthesia as the fractured hip fixation. Clinical evaluation includes pain evaluation, functional status, and osteointegration of the device. \u0000Mean age of patients was 82 ± 7 years. Mean duration of implantation was 56 ± 19 min for Y-STRUT® implantation and 37 ± 24 for fracture fixation in the opposite side. Mean cement quantity injected was 8 ± 1.6 ml. At 3 months, WOMAC scores for pain and functionality were 5 and 24, respectively and 4 and 18 at 12 months. Mean follow-up is 16 ± 12 months. No patient died during the follow-up. No osteolysis nor post-operative fracture were observed. \u0000Preliminary results of this prospective study showed the feasibility, safety and tolerance of the implantation of this new device. Further patients are required to confirm this experience and confirm efficacy of the device to reduce the risk of contralateral hip fracture during the first year after the first fracture when elderly patients are at the highest risk of fracture and mortality and the anti-osteoporosis medication prescribed at fracture is not yet efficient.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"5 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41640614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Potential Benefits of Annatto Tocotrienol in Glucocorticoid Induced Osteoporosis: An Animal Study Annatto Tocotrienol对糖皮质激素诱导的骨质疏松症的潜在益处：一项动物研究

Journal of osteoporosis and physical activity Pub Date : 2017-06-21 DOI: 10.4172/2329-9509.1000203

I. Soelaiman, E. Ramli, F. Suhaimi, Fairus Ahmad

{"title":"Potential Benefits of Annatto Tocotrienol in Glucocorticoid Induced Osteoporosis: An Animal Study","authors":"I. Soelaiman, E. Ramli, F. Suhaimi, Fairus Ahmad","doi":"10.4172/2329-9509.1000203","DOIUrl":"https://doi.org/10.4172/2329-9509.1000203","url":null,"abstract":"Long-term glucocorticoid treatment induces oxidative stress that cause osteoporosis is an antioxidant and has protective effects against free radical associated diseases. Annatto tocotrienol is a tocopherol free tocotrienol mixture. The purpose of this study was to determine the effects of annatto tocotrienol against glucocorticoid-induced osteoporosis. 32 adult male Sprague-Dawley rats were used in this study. 16 rats were adrenalectomized and divided into two groups; Adrx+Dexa and Adrx+Dexa+ATT and were administered with intramuscular injection of dexamethasone 120 μg/kg/ day. Eight rats underwent sham procedure and the other 8 serves as baseline group. The Adrx+Dexa group was given vehicle palm olein 0.1 ml/kg/day orally while Adrx+Dexa+ATT group was supplemented with annatto tocotrienol 60 mg/ kg/day. The sham operated rats were given vehicle palm olein 0.05 ml/kg/day by intramuscular injection and 0.1 ml/ kg/day orally. The treatments were given for two months before the rats were euthanized. The femurs were tested for biomechanical strength and analyzed for bone histomorphometry. The results showed that long-term glucocorticoid treatment increased, bone resorption marker (CTX), lipid peroxidation; and decreased superoxide dismutase (SOD) activity with no significant changes to serum osteocalcin. Bone biomechanical strength was compromised with reduction in structural, static and dynamic parameters of bone histomorphometry. Annatto tocotrienol supplementation had maintained lipid peroxidation, CTX level, SOD activity and protected bone histomorphometric parameters and biomechanical strength. The results of this study suggested that annatto tocotrienol may have protective effects against osteoporosis induced by glucocorticoids and may be used as prophylaxis for patients on long term glucocorticoid therapy.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":"5 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42545970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Atypical Femur Fractures and Cortical Thickening in Osteoporotic Patients Treated with Bisphosphonates 双膦酸盐治疗骨质疏松症患者的不典型股骨骨折和皮质增厚

Journal of osteoporosis and physical activity Pub Date : 2017-06-05 DOI: 10.4172/2329-9509.1000201

M. Curiel, N. Martin, R. A. Pinel

{"title":"Atypical Femur Fractures and Cortical Thickening in Osteoporotic Patients Treated with Bisphosphonates","authors":"M. Curiel, N. Martin, R. A. Pinel","doi":"10.4172/2329-9509.1000201","DOIUrl":"https://doi.org/10.4172/2329-9509.1000201","url":null,"abstract":"Background: Patients treated with bisphosphonates (BP) may present atypical femoral fractures (AFF) as a complication with an incidence of 3.2-50 cases per 10,000 person-years. The existence of cortical thickening is sometimes related to the appearance of atypical fracture. So, from the clinical point of view, in patients treated with bisphosphonates, the appearance of cortical thickening must suggest the change of treatment in order to avoid fractures. \u0000Case report: We present a case of atypical fracture, with bilateral cortical thickening as a predictor of atypical femur fracture, in a patient using BP for years. The main symptom developed by the patient through the years BP were taken was bilateral thigh pain. \u0000Conclusion: There is some evidence of a relationship between long-term BP and a specific type of femoral fracture with radiographic features (including cortical thickening) and some clinical features as prodromal pain. However, atypical fractures are uncommon, and with correct indication, the utility of antiresorptives are not discussed. Physicians and patients should know the possibility of AFF and the possible bilateral involvement of this rare complication, in order to assess the risk-benefit of continuing/withdrawing treatment with BPs.","PeriodicalId":92253,"journal":{"name":"Journal of osteoporosis and physical activity","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9509.1000201","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43967321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-vivo DEXA in large animal models: Does animal anatomy and positioning hold the clinical standards? 大型动物模型中的体内DEXA：动物解剖和定位符合临床标准吗？

Journal of osteoporosis and physical activity Pub Date : 2017-04-10 DOI: 10.4172/2329-9509.1000200

Deeksha Malhan, T. Khassawna, C. Heiss

引用次数: 0

Biosensors For the Measurement of C-Terminal Telopeptide of Type I Collagen (CTX-I) 测量I型胶原c端末端肽(CTX-I)的生物传感器

Journal of osteoporosis and physical activity Pub Date : 2017-04-09 DOI: 10.4172/2329-9509.1000199

Nasrin Afsarimanesh, S. Mukhopadhyay, M. Kruger

引用次数: 9