BMC Anesthesiology最新文献

{"title":"Comparison of the effectiveness of two different concentrations of ropivacaine for intrapleural analgesia in reducing stimulatory pain caused by chest tubes after uniportal video-assisted thoracoscopic surgery: a randomised controlled study.","authors":"Wenjing Tang, Yonggang Hao, Gangming Wu, Haixia Wang","doi":"10.1186/s12871-025-02992-5","DOIUrl":"10.1186/s12871-025-02992-5","url":null,"abstract":"<p><strong>Background: </strong>Pain caused by chest tube placed after uniportal video-assisted thoracoscopic surgery (UVATS) is often neglected. Ropivacaine can be used to alleviate pain related to the chest tube, but the current lowest effective concentration of ropivacaine remains unclear.</p><p><strong>Methods: </strong>To investigate the analgesic effect of administering two different concentrations of ropivacaine into the pleural cavity via pleural drainage tube bypass after UVATS. Ninety patients were randomly divided into three groups: Control group (PCIA only), Low-dose group (PCIA combined with intrathoracic infusion of 200 ml 0.25% ropivacaine), Medium-dose group (PCIA combined with intrathoracic infusion of 200 ml 0.5% ropivacaine). The analysis included Visual Analogue Scale (VAS) scores for chest tube-related pain and surgical incision pain at 6 h, 12 h, 24 h, and 48 h post-operation for each group. Compare incidence of adverse reactions (respiratory depression, hypotension, nausea/vomiting, arrhythmia, dizziness) within 48 h.</p><p><strong>Results: </strong>Compared to the control group, both 0.25% and 0.50% ropivacaine effectively reduced chest tube-related pain (P < 0.001) and surgical incision pain (P < 0.001) at 6 h, 12 h, 24 h, and 48 h postoperatively. However, no significant differences were observed between the two concentrations of ropivacaine in alleviating rest and cough pain related to the chest tube (P > 0.05) or surgical incision (P > 0.05) within 48 h postoperatively. Adverse reaction rates were similar among groups within 48 h postoperatively (P = 0.383).</p><p><strong>Conclusion: </strong>The analgesic effect of ropivacaine infusion with concentrations of 0.25% and 0.50% administered via intrathoracic pumps for chest tube-related pain after UVATS showed no significant difference, but both were superior to the sole use of PCIA.</p><p><strong>Registration: </strong>Chinese Clinical Trial Registry ChiCTR2200065184.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"119"},"PeriodicalIF":2.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11899763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orbital fistula tract - a case report of a rare cause of impossible facemask ventilation.","authors":"Christian Volberg, Kuo-Min Kwee, David Sun, Hinnerk Wulf","doi":"10.1186/s12871-025-02989-0","DOIUrl":"10.1186/s12871-025-02989-0","url":null,"abstract":"<p><strong>Background: </strong>Adequate facemask ventilation during induction of anaesthesia is a key aspect of patient safety. Difficulties can therefore be life-threatening for the patient.</p><p><strong>Case presentation: </strong>The case presented here illustrates a rare cause of an orbital fistula that led to a serious problem during facemask ventilation and demonstrates why team communication is so important.</p><p><strong>Conclusions: </strong>Preparatory errors in patient assessment and anaesthetic preparation were identified as sources of error.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"120"},"PeriodicalIF":2.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11900649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dexmedetomidine administration is associated with reduced mortality in patients with sepsis-induced acute respiratory distress syndrome: a retrospective study.","authors":"Jianguo Zhang, Zhaoyuan Jia, Yu Zhang, Zhimin Tao","doi":"10.1186/s12871-025-02961-y","DOIUrl":"10.1186/s12871-025-02961-y","url":null,"abstract":"<p><strong>Background: </strong>Although studies have revealed the benefits of using dexmedetomidine (DEX) in treating rodent models of acute lung injury (ALI) by improving their survival rates, clinical investigation on the effect of DEX on patients with acute respiratory distress syndrome (ARDS) remains scarce. Through this retrospective study, we aim to better understand the underlying mechanism of sepsis-induced ARDS and the effect of DEX on patients' standard treatment.</p><p><strong>Methods: </strong>A total of 208 patients with sepsis-induced ARDS, admitted to the intensive care unit (ICU) at Affiliated Hospital of Jiangsu University, China, from January 2017 to December 2019, were included. The patients were divided into the control group (n = 102) and the DEX group (n = 106). Both groups of patients received mechanical ventilation and standard care; however, the DEX group was additionally treated with DEX as a sedative. Demographic information, baseline characteristics, laboratory parameters, arterial blood gas (ABG) analyses, and inflammatory indicators were compared between the two groups to evaluate the therapeutic outcomes of different treatment approaches.</p><p><strong>Results: </strong>Age and male gender constituted risk factors for high ARDS incidence, and hypertension led in the list of patients' comorbidities. The baseline characteristics including primary diagnosis and ARDS causes, and prognostic values such as the Acute Physiology and Chronic Health Evaluation (APACHE) II score and predicted mortality, were comparable between the two groups of patients. However, the multiple organ dysfunction syndrome (MODS) incidence and actual mortality rate were significantly lower in the DEX group compared to the control group. Additionally, the DEX group demonstrated improved ABG metrics, representing better acid-base balance and oxygenation, and enhanced inflammatory responses.</p><p><strong>Conclusions: </strong>Intravenous administration of DEX was associated with reduced in-hospital mortality, at least in part, by ameliorating ABG indices and inflammatory mediators.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"118"},"PeriodicalIF":2.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of the sympathetic component of the autonomic nervous system on pain before and after third molar extraction- an observational cohort study.","authors":"Christophe Deschaumes, Laurent Devoize, Yannick Sudrat, Bruno Pereira, Radhouane Dallel, Christian Dualé","doi":"10.1186/s12871-025-02949-8","DOIUrl":"10.1186/s12871-025-02949-8","url":null,"abstract":"<p><strong>Background: </strong>Assessing heart rate variability (HRV) before a standardized surgery would help to explore further the relationship between the autonomic nervous system and pain.</p><p><strong>Methods: </strong>A single-center prospective cohort of 117 patients (55% female) scheduled for third molar extraction underwent a preoperative resting measurement of arterial pressure followed by an HRV recording, then potentiated by a Valsalva maneuver and a deep breathing challenge. Finally, pain sensitivity was assessed by hand immersion in hot water. All surgeries were conducted under local anesthesia, with or without sedation. The primary outcome was a composite pain/analgesia score (CPAS) incorporating both pain intensity and analgesic drug intake; it was adjusted to the type of anesthesia by within-subgroup ranking.</p><p><strong>Results: </strong>The increase in heart rate in the Valsalva maneuver, and the low- to high-frequency ratio (LF/HF) in the deep breathing, were inversely correlated to preoperative heat pain, which was correlated itself to the CPAS (ρ = 0.195; p = 0.035). The only other parameter influencing CPAS was the increase in heart rate in the Valsalva maneuver, with an inverse correlation (ρ = - 0.191; p = 0.046). While age tended to impair HRV, particularly in its parasympathetic component, and while men displayed a stronger parasympathetic response than women, neither age nor sex interacted with these effects. Neither preoperative arterial pressure nor the occurrence of parental hypertension influenced the pain outcomes.</p><p><strong>Discussion: </strong>Although the identified relationships were not particularly strong, they are consistent with an influence of the sympathetic component of the autonomic nervous system. However, they do not support the interest of HRV assessment to predict postoperative pain in current practice.</p><p><strong>Trial registration: </strong>Not applicable.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"117"},"PeriodicalIF":2.3,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apnoeic oxygenation in pediatric anesthesia: better safe than sorry!","authors":"Davut Deniz Uzun, Felix Hezel, Stefan Mohr, Markus A Weigand, Felix C F Schmitt","doi":"10.1186/s12871-025-02995-2","DOIUrl":"10.1186/s12871-025-02995-2","url":null,"abstract":"<p><strong>Background: </strong>Children, especially neonates and infants, are at particularly high risk of hypoxemia during induction of anesthesia. The addition of nasal apnoeic oxygenation (ApOx) during tracheal intubation should prolong safe apnoea time without desaturation and reduce the risk of hypoxemia. Despite the recommendations in the relevant European guidelines, their implementation in pediatric anesthesia in Germany is not yet known.</p><p><strong>Methods: </strong>A survey was conducted in July and October 2024 via email to all registered members of the scientific working group on airway management, the scientific working group on pediatric anesthesia of the German Society of Anesthesiology and Intensive Care Medicine (DGAI) and hospitals of all levels in Germany. Participants were asked about their personal and institutional background and the use of ApOx in pediatric anesthesia in their institution.</p><p><strong>Results: </strong>Of the eight hundred participants invited, 304 anesthetists completed the survey (response rate 38%). In addition, 36 of 109 invited anesthetists from the scientific working group on pediatric anesthesia were interviewed as a separate expert group. 201 (66.1%) of the anesthetists surveyed in the general group stated that they worked regular in pediatric anesthesia (pediatric anesthesia expert group: 94.4%). 64.2% of the general respondents considered pediatric patients to be at an increased risk of reduced apnoea time. 46.7% of the general participants are of the opinion that pediatric patients should generally not receive ApOx during induction of anesthesia. If ApOx is performed, then most likely with a standard nasal cannula. ApOx was generally used in infants with an oxygen flow rate of ≤ 2 l/min or 0.2 l/kg bodyweight/min. A relevant proportion of anesthetists were unaware that current European guidelines recommend ApOx for neonates and infants (general participants: 62.5%, pediatric anesthesia expert group: 39%).</p><p><strong>Conclusions: </strong>Despite the recommendations in the guidelines, the use of ApOx does not appear to be standard practice at present. Furthermore, the surveyed physicians exhibited considerable uncertainty regarding ApOx. It is imperative that further improvements are made in the dissemination of the current guidelines with a view to enhancing patient safety during pediatric anesthesia.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"116"},"PeriodicalIF":2.3,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Local analgesia for the relief of pain in children undergoing venipuncture and intravenous cannulation: a systematic review and network meta-analysis.","authors":"Liping Zhao, Ping Qi, Xue Wang, Xiaolei Su, Limei Liao","doi":"10.1186/s12871-025-02991-6","DOIUrl":"10.1186/s12871-025-02991-6","url":null,"abstract":"<p><strong>Background: </strong>Venipuncture and intravenous cannulation are common procedures in hospitals that often cause pain, particularly in children. Despite the availability of various local analgesia methods to alleviate needle-associated pain, the most effective approach remains unknown. The objective of this study is to compare and rank the efficacy of different local analgesia methods in reducing pain in children undergoing venipuncture and intravenous cannulation.</p><p><strong>Method: </strong>Six databases including PubMed, Embase, CINAHL, Scopus, Web of Science, and the Cochrane Library were searched from January 1,1990 to December 1,2024. The primary outcome is the self-reported pain. We assessed the certainty of the body of evidence from the NMA for the primary outcome based on CINeMA.</p><p><strong>Result: </strong>40 RCTs consisting of 4481 children and 9 local analgesia methods were included in the analysis. Results showed that vapocoolant spray was no more effective than placebo or routine care in reducing needle-associated pain in children. Other interventions including EMLA cream, lidocaine cream, lidocaine iontophoresis, amethocaine, needle-free lidocaine injection system, EMLA patch, lidocaine/tetracaine heating patch and Buzzy produced greater pain reduction in children compared to placebo and routine care. Amethocaine was the most effective local analgesia method with the probability of 57.6% being the best, followed by Buzzy and lidocaine iontophoresis with the probability of 17.0% and 8.4%, respectively.</p><p><strong>Conclusion: </strong>Most local analgesia methods were effective in relieving pain in children undergoing venipuncture and intravenous cannulation except vapocoolant spray which did not show greater pain reduction than placebo or routine care. Amethocaine, Buzzy and lidocaine iontophoresis are the top 3 local analgesia methods to relieve pain in children undergoing venipuncture and intravenous cannulation. However, due to the limited number of direct comparisons, interpretation of some results should be made with caution.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"115"},"PeriodicalIF":2.3,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11887248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the impact of frailty on postoperative delirium in elderly surgical patients: a systematic review and meta-analysis.","authors":"Haotian Wu, Siyi Yan, Han Cao, Chunyu Feng, Huan Zhang","doi":"10.1186/s12871-025-02994-3","DOIUrl":"10.1186/s12871-025-02994-3","url":null,"abstract":"<p><strong>Background: </strong>Frailty has been consistently implicated as a pivotal factor in the onset of delirium following anesthesia and surgery. Nonetheless, a comprehensive understanding of the relationship between frailty and delirium remains to be elucidated. This study addresses that knowledge gap.</p><p><strong>Methods: </strong>A comprehensive search of literature databases identified 43 relevant studies involving 14,441 participants. The studies were subjected to a rigorous quality assessment using the Newcastle-Ottawa Scale. Statistical analysis was conducted using Review Manager (v5.4.1), including subgroup and sensitivity analyses.</p><p><strong>Results: </strong>Meta-analysis revealed a significant association between preoperative physical frailty and postoperative delirium (pooled odds ratio: 2.47; 95% confidence interval: 2.04-2.99; I² = 46.7%). The baseline frailty rate was 34.0% (4,910/14,441), while the overall incidence of postoperative delirium was 20% (2,783/14,441). Subgroup analyses based on characteristics such as race, frailty-assessment tools, and surgical types were conducted to explore potential sources of heterogeneity. This meta-analysis provided compelling evidence supporting a notable link between preoperative physical frailty and an increased risk of postoperative delirium in older surgical patients. Early identification through frailty screening can enable targeted interventions, potentially enhancing overall management and individualized treatment. Integrating frailty assessment into preoperative evaluation may improve predictive accuracy in surgical planning and anesthesia management.</p><p><strong>Conclusions: </strong>Future research could focus on optimizing the integration of frailty assessment into preoperative protocols for timely intervention and improved patient outcomes.</p><p><strong>Trial registration: </strong>The review protocol was registered with PROSPERO (CRD42023390486), date of registration: Aug 11, 2023.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"114"},"PeriodicalIF":2.3,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between monocyte and length of in-hospital stay in patients with allergic rhinitis: data from the MIMIC-IV database.","authors":"Die Fang, Jing Li, Ping Fang, Zhi-Qi Ma, Hui-Ju Huang, Guo-Ping Qian, Jing Zhao, Yan Shi","doi":"10.1186/s12871-025-02979-2","DOIUrl":"10.1186/s12871-025-02979-2","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to explore the factors associated with the length of in-hospital stay (LOS) in allergic rhinitis (AR).</p><p><strong>Methods: </strong>Patients with AR and related data were identified from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. The influencing factors of LOS were determined by correlation analysis and linear regression. We ranked the importance of significant variables. Finally, mediation analysis was performed to explore the potential mediating factors associated with LOS.</p><p><strong>Results: </strong>This retrospective study enrolled 937 patients diagnosed with AR. Correlation analysis showed that 10 variables were closely correlated with the LOS. Linear regression further showed that albumin, white blood cell (WBC), red blood cell (RBC), red cell distribution width (RDW), total Ca, and monocyte were independently related to the LOS (all P < 0.05). After considering comorbidities, monocyte, albumin, WBC, RBC, total Ca, and Charlson comorbidity index were independent factors for LOS (all P < 0.05). The permutation importance exhibited that monocyte was the most important variable. Finally, mediation analysis demonstrated that WBC played a mediating role in the relationship between monocytes and LOS.</p><p><strong>Conclusion: </strong>Monocyte level is related to the LOS of patients with AR, and their relationship can be mediated by WBC. Medical and nursing staff can stratify AR management according to monocyte levels to make crucial clinical decisions and shorten LOS.</p><p><strong>Clinical trial: </strong>Not applicable.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"113"},"PeriodicalIF":2.3,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of ciprofol for gastroscopy in patients with obesity: a randomised clinical controlled trial using different weight-based dosing scales.","authors":"Danru Xie, Yanjing Zhang, Feifei Li, Yaoheng Yang, Mengjiao Che, Geng Li, Yiwen Zhang","doi":"10.1186/s12871-025-02974-7","DOIUrl":"10.1186/s12871-025-02974-7","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to compare the efficacy and safety of ciprofol-induced doses based on three indices: total body weight (TBW), ideal body weight (IBW), and lean body weight (LBW) in patients with obesity undergoing gastroscopy.</p><p><strong>Methods: </strong>In a single-centre, prospective, randomised study conducted at an endoscopy centre, a total of 108 patients aged 18-65 years who underwent painless gastroscopy and had a body mass index (BMI) of 28-39.9 kg/m² were included. Patients with obesity from the intended study population were randomised to receive a ciprofol infusion (0.4 mg/kg) for the induction of anaesthesia based on TBW (Group T), IBW (Group I), or LBW (Group L). A Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale score of < 1 was considered a marker of loss of consciousness, prompting gastroscopy. The primary outcomes were the success rate of anaesthesia for the procedures, and that of general anaesthesia achieved using the initial dose. Secondary outcomes included the frequency of remedial sedation, total ciprofol dose, and adverse events RESULTS: The procedure success rate was 100% in all three groups. Compared to Group L, the general anaesthesia success rate achieved with the initial dose was higher and the frequency of remedial sedation was lower in Groups T and I. Compared to Group L, fewer patients in Group T required additional medication. Compared to Group T, the occurrence of hypoxaemia was lower in the remaining two groups, and Group L had a lower incidence of posterior tongue drops and hypotension.</p><p><strong>Conclusions: </strong>Induction doses of ciprofol based on TBW or IBW provided better anaesthesia than doses based on LBW for gastroscopy in patients with obesity. LBW-based induction doses of ciprofol improved cardiovascular stability and respiratory safety, whereas IBW-based induction doses of ciprofol reduced respiratory depression.</p><p><strong>Trial registration: </strong>This study was registered in the Chinese Clinical Trial Registry (ChiCTR2300073539 first registration date 13/07/2023).</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"112"},"PeriodicalIF":2.3,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of the new non-inflatable laryngeal mask GMA-Tulip on airway management for lateral total hip arthroplasty in geriatric patients: a randomized controlled trial.","authors":"Qiang Zhang, Shiyang Dong, Chonglong Shi, Wenjie Jin","doi":"10.1186/s12871-025-02985-4","DOIUrl":"10.1186/s12871-025-02985-4","url":null,"abstract":"<p><strong>Background: </strong>The supraglottic airway device (SAD) is nowadays widely used as a ventilation device. The GMA-Tulip is a new non-inflatable SAD used to establish short-term artificial airway for general anesthesia or cardiopulmonary resuscitation. In the present study, we compare the clinical performance of the GMA-Tulip and the LMA Supreme for lateral total hip arthroplasty in geriatric patients.</p><p><strong>Methods: </strong>In 70 anesthetized and paralyzed adult patients, the GMA-Tulip (n = 35) or the LMA Supreme (n = 35) was inserted. The primary outcome was oropharyngeal leak pressure (OLP). The secondary outcomes included the peak airway pressure (PAP), insertion time, insert resistance, number of insertion attempt and manipulations, glottic exposure grading, and incidence of perioperative complications.</p><p><strong>Results: </strong>The GMA group had a significantly higher OLP and lower PAP at the 4 measurement points than did the Supreme group (P < 0.05). Compared with that in the supine position, the OLP of the two groups was significantly lower in the lateral position (P < 0.05). The LMA Supreme had a longer insert time (36(32,39) vs. 18(15,22) sec; P < 0.001) and was inserted more difficultly (P < 0.05). The sore throat scores one hour after surgery at the LMA Supreme was higher than that at the GMA-Tulip (P < 0.05), but the incidence of blood staining was not different between the two groups (P = 0.106).</p><p><strong>Conclusions: </strong>The GMA-Tulip and LMA Supreme both provided considerable ventilation efficiency during lateral total hip arthroplasty in geriatric patients. Our data showed that new non-inflatable laryngeal mask GMA-Tulip has a higher OLP and demonstrated a shorter time to successful placement and a lower sore throat score one hour after surgery compared with the LMA Supreme.</p><p><strong>Trial registration: </strong>The trial was retrospectively registered on August 30, 2024 in the Chinese Clinical Trial Registry, registration number ChiCTR2400088996 (30/08/2024).</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"111"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}