BMC Musculoskeletal Disorders最新文献

{"title":"Clinical prediction models for postoperative blood transfusion after total knee arthroplasty: a systematic review and meta-analysis.","authors":"Jingwen Chen, Xiaoping Zhong, Yaojie Zhai, Cuixian Zhao, Jingjing Lan, Liping Chen, Zhenlan Xia","doi":"10.1186/s12891-025-09164-z","DOIUrl":"10.1186/s12891-025-09164-z","url":null,"abstract":"<p><strong>Background: </strong>Postoperative blood transfusion remains a significant concern following total knee arthroplasty. Clinical prediction models can facilitate early identification of patients at risk, enabling targeted blood management to reduce unnecessary transfusions and related complications. However, the predictive performance, methodological quality, and clinical applicability of these models remain uncertain. Therefore, we systematically reviewed existing models for predicting postoperative transfusion in total knee arthroplasty.</p><p><strong>Methods: </strong>Ten English and Chinese databases were comprehensively searched from database inception to February 2025 to identify relevant studies. Two reviewers independently extracted data based on the checklist for Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies (CHARMS). The risk of bias and the applicability of each study was evaluated applying the Prediction model Risk Of Bias Assessment Tool (PROBAST). Extracted AUC of included models were pooled and analyzed utilizing a random-effects meta-analysis. A leave-one-out sensitivity analysis and an exploratory subgroup meta-analysis by modelling approach were also conducted to explore the sources of heterogeneity. All statistical analyses were performed in Stata 17.0 software.</p><p><strong>Results: </strong>Twelve studies involving eighteen models were incorporated in this review. All studies established the prediction models employing logistic regression or machine learning methods. The most commonly used predictors were preoperative hemoglobin, age, body mass index, surgery duration, and the use of tranexamic acid. The pooled AUC for the six internally validated models was 0.83 (95% CI: 0.74-0.92), demonstrating a relatively high predictive discrimination. Sensitivity analysis did not materially change the estimates, and the subgroup meta-analyses showed that the modelling approach alone could not explain the heterogeneity (p = 0.406). However, all model were considered as having a high risk of bias, mainly owing to the unsuitable study design and poor reporting within the analysis domain.</p><p><strong>Conclusions: </strong>Despite the included studies demonstrating moderate to excellent discrimination for predicting postoperative transfusion after total knee arthroplasty, all studies were considered as having a high risk of bias following the PROBAST due to some methodological shortcomings and inadequate external validation. Future research should focus on improving methodological quality and performing multicenter external validation to ensure clinical applicability.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"892"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of surgically treated degenerative cervical and lumbar spine diseases using multiple clinical aging indices.","authors":"Ryosuke Kurihara, Yuki Akaike, Takehiro Michikawa, Takao Tobe, Risa Tobe, Soya Kawabata, Sota Nagai, Takaya Imai, Hiroki Takeda, Shinjiro Kaneko, Shigeki Yamada, Nobuyuki Fujita","doi":"10.1186/s12891-025-09185-8","DOIUrl":"10.1186/s12891-025-09185-8","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of degenerative spine diseases has continued to rise with the aging of the global population. Despite the availability of various aging indices, limited studies have comprehensively investigated degenerative spine diseases from the perspective of aging. This study aimed to evaluate degenerative cervical and lumbar diseases surgically treated using multiple clinical aging indices and elucidate the characteristics of each condition through comparative analysis.</p><p><strong>Methods: </strong>Clinical data of consecutive patients aged ≥ 65 years who underwent surgery for degenerative cervical and lumbar diseases were retrospectively collected. Frailty was assessed using the 11-point modified frailty index. Locomotive syndrome stage was determined based on the 25-Question Geriatric Locomotive Function Scale. Functional decline was assessed according to the Kihon Checklist. Polypharmacy was defined based on a cutoff of six drugs. A total of 19 categories were considered potentially inappropriate medications.</p><p><strong>Results: </strong>Among the included patients, 313 and 103 had degenerative lumbar (L group) and degenerative cervical (C group) diseases, respectively. The C group had significantly lower serum albumin levels (p = 0.03), a significantly higher frequency of functional decline in both physical function (p = 0.02) and activities of daily living (p = 0.046), and significantly more advanced frailty (p = 0.004) than the L group. Among potentially inappropriate medications, the frequency of diuretic use was significantly higher in the C group than in the L group (p = 0.04). Longitudinal observations showed significant postoperative improvements in locomotive syndrome stages in the L group but not the C group. Cross-sectional observations revealed no significant differences in locomotive syndrome stage distributions between both the groups before surgery (p = 0.402); however, the C group exhibited significantly more advanced locomotive syndrome stages than the L group at 6 months (p < 0.001) and 1 year after surgery (p < 0.001).</p><p><strong>Conclusions: </strong>Across various indices of aging, patients with degenerative cervical spine disease showed more significant progression than those with lumbar spine disease. Thorough understanding of these characteristics is essential when managing degenerative spine diseases, particularly in the selection of effective treatment approaches for the increasingly aging society in the future.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"902"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiomics and deep learning model based on X-ray imaging for the assisted diagnosis of early Legg-Calvé-Perthes disease.","authors":"Dian Zhang, Ya-Nan Li, Cheng-Long Li, Wan-Liang Guo","doi":"10.1186/s12891-025-09189-4","DOIUrl":"10.1186/s12891-025-09189-4","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"910"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of minimally invasive plate osteosynthesis in the management of displaced midshaft clavicle fractures: a case-control study.","authors":"Huaibo Wang, Ruiyang Xue, Zhuming Chen, Kaiyuan Zhu, Yanhan Zhou, Liunan Zhou, Sijing Liu, Weitao Guo, Kai Li","doi":"10.1186/s12891-025-08995-0","DOIUrl":"10.1186/s12891-025-08995-0","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"905"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety of autologous nucleus pulposus cell transplantation with fibrin glue following endoscopic discectomy in chronic low back pain: a preliminary phase I trial.","authors":"Bahareh Sadri, Narges Labibzadeh, Hoda Madani, Alireza Beheshti Maal, Maryam Niknejadi, Nikoo Hossein-Khannazer, Shayan Farzanbakhsh, Shahedeh Karimi, Mohammad Hassanzadeh, Abolfazl Bagherifard, Mohsen Emadedin, Massoud Vosough","doi":"10.1186/s12891-025-09186-7","DOIUrl":"10.1186/s12891-025-09186-7","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"901"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.","authors":"Xiaoya Liu, Jiayi Guo, Yapeng Li, Yidan Yang, Mengyao Liu, Qi Gao, Yuxia Yang, Xiaolong Wu, Chen Yue","doi":"10.1186/s12891-025-09163-0","DOIUrl":"10.1186/s12891-025-09163-0","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"906"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy and radiological outcomes of a novel screw placement technique for the treatment of traumatic thoracolumbar vertebral fractures under navigation guidance.","authors":"Biwang Huang, Kangheng Niu, Le Cheng, Zhong Wei, Xuepeng Wang, Zhenzhen Tao, Tanjun Wei, Feng Xu, Chengjie Xiong","doi":"10.1186/s12891-025-09071-3","DOIUrl":"10.1186/s12891-025-09071-3","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"896"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of percutaneous release versus steroid injection among adults with trigger fingers: a randomized clinical trial.","authors":"Mandeep Karki, Rachit Sharma, Dev Ram Sunuwar, Rama Shankar Gupta, Devendra Raj Singh, Sunima Lama, Kailash Kumar Bhandari, Ram Krishna Tamang, Narendra Kumar Chaudhary","doi":"10.1186/s12891-025-08981-6","DOIUrl":"10.1186/s12891-025-08981-6","url":null,"abstract":"<p><strong>Background: </strong>Trigger finger (TF) causes pain and impaired hand function. Percutaneous release of the A1 pulley demonstrates a better outcome than steroid injection in the treatment of TF; however, evidence remains limited. Therefore, this study aimed to compare the effect of percutaneous release of the A1 pulley compared to local steroid injection in the treatment of trigger fingers in Nepal.</p><p><strong>Methods: </strong>A hospital-based randomized clinical trial among 92 patients aged 18 years and above suffering from trigger fingers that were unresponsive to conservative treatment was conducted to evaluate the effect of the percutaneous release of A1 pulley and steroid injection. Quinnell's classification, visual analogue scale (VAS) scoring system and thickness of A1 pulley, as well as the flexor tendon in the affected site, were assessed before and after intervention at six months. Student's t-test, Mann-Whitney U test and chi-square tests were performed to compare the effectiveness of both treatments.</p><p><strong>Result: </strong>Percutaneous release of the A1 pulley showed better functional improvement than steroid injection, with a p-value of < 0.001 and medium effect size of 0.43. The pain score was also decreased more in the percutaneous release group than the steroid group (-5.1 ± 1.4 versus - 3.7 ± 1.8), with the group difference of 1.3 (95% CI: 0.6 to 2.0), with a p-value of < 0.001 and a large effect size of 0.87. Nevertheless, steroid injection decreased the thickness of A1 pulley than percutaneous release (-0.34 ± 0.24 versus - 0.21 ± 0.21), with a p-value of 0.011 and a large effect size of 0.5. Furthermore, tendon thickness was decreased more in the steroid group compared with the percutaneous release group (-1.12 ± 0.73 versus - 0.34 ± 0.41), with a p-value of < 0.001 and a huge effect size of 1.31.</p><p><strong>Conclusion: </strong>Percutaneous release of A1 pulley illustrated greater improvement in functional mobility with a moderate effect size and pain with a large effect size compared to steroid injection in trigger fingers. A multicenter trial with a larger sample size and involving a diverse participant cohort may enhance the strength of the evidence.</p><p><strong>Trial registration: </strong>NCT05383040, first registered on 17/05/2022 (https//clinicaltrials.gov/ct2/show/NCT05383040).</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"885"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of safety boots and their relationships with the foot structure of female and male industrial workers.","authors":"Ewa Puszczalowska-Lizis, Sabina Lizis, Wioletta Mikulakova, Dorota Kubicz, Lucia Demjanovic Kendrova, Jaroslaw Omorczyk","doi":"10.1186/s12891-025-08983-4","DOIUrl":"10.1186/s12891-025-08983-4","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"897"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D-printed navigation-guided FNS-CCS fixation reduces complications in young adults with comminuted femoral neck fractures: a retrospective cohort study.","authors":"Ting Fu, Kailong Geng, Li Li, Donglin Fu, Zongsheng Yin","doi":"10.1186/s12891-025-09100-1","DOIUrl":"10.1186/s12891-025-09100-1","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"894"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}