Dong-Ho Kang, Jonghyuk Baek, Bong-Soon Chang, Sam Yeol Chang, Dongook Kim, Sanghyun Park, Hyoungmin Kim
{"title":"Can we predict post-surgical improvement in functional stooping in lumbar spinal stenosis? Insights from oblique lumbar interbody fusion outcomes and radiologic predictors.","authors":"Dong-Ho Kang, Jonghyuk Baek, Bong-Soon Chang, Sam Yeol Chang, Dongook Kim, Sanghyun Park, Hyoungmin Kim","doi":"10.1186/s12891-025-08821-7","DOIUrl":"10.1186/s12891-025-08821-7","url":null,"abstract":"<p><strong>Background: </strong>Functional stooping, characterized by a forward-flexed lumbar posture in patients with lumbar spinal stenosis (LSS), serves as a compensatory mechanism aimed at alleviating pain by expanding the constricted spinal canal. Surgeons widely use the oblique lateral interbody fusion (OLIF) to treat patients with LSS, restoring segmental lordosis in index surgical level. In some patients with LSS, improvement of global sagittal imbalance occurs after short-level OLIF. it remains unclear whether this is predominantly due to segmental correction or the resolution of functional stooping. Therefore, this study aimed to evaluate the effect of functional stooping resolution and segmental correction on sagittal imbalance after short-level OLIF, and identifying predictors of presence or absence of preoperative functional stooping in LSS.</p><p><strong>Methods: </strong>A retrospective review was conducted on LSS patients who underwent single or two-level OLIF with preoperative C7 sagittal vertical axis (SVA) > 50 mm. The clinical and radiological factors were analyzed. Logistic regression and receiver operating characteristic curve analysis were conducted to identify factors associated with presence or abscence of preoperative functional stooping, and to establish predictive threshold values, respectively.</p><p><strong>Results: </strong>A total of 103 patients with a mean age of 71.6 ± 8.6 years were included. In patients with preoperative functional stooping, segmental correction at the index surgical level contributed to only 47.7% of the total change of lumbar lordosis (LL), whereas the change of lordosis in remnant mobile lumbar segments constituted 52.3% of the total change of LL. Preoperative thoracic kyphosis (TK) (OR [95% CI]: 1.037 [1.002-1.073]), and preoperative SVA (OR [95% CI]: 0.986 [0.972-0.999]) were significant associated factors for predicting LSS patients without functional stooping.</p><p><strong>Conclusions: </strong>Functional stooping resolution markedly impacts global sagittal balance correction in LSS patients following short-level OLIF. Preoperative functional stooping correlates with greater TK and reduced SVA. For patients likely to achieve functional stooping resolution, single-level surgery may suffice initially, with deformity correction reserved if needed.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"670"},"PeriodicalIF":2.2,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qi-Ning Qin, Xin Zhang, Ying-Feng Cai, Tian-Zhao Tian, Jian-Peng Zhou, Lin Li, Min Shi, Peng Huang, Hao-Dong Liang, Jia-Hui Li, Zhan-Liang Tan, Yi-Xuan Fang, Jia-Wen Wang, Fang Zheng, Bao-Xin Liu
{"title":"Heel kicking exercise rapidly improves pain and function in patients with acute lateral ankle sprain: a randomized controlled trial.","authors":"Qi-Ning Qin, Xin Zhang, Ying-Feng Cai, Tian-Zhao Tian, Jian-Peng Zhou, Lin Li, Min Shi, Peng Huang, Hao-Dong Liang, Jia-Hui Li, Zhan-Liang Tan, Yi-Xuan Fang, Jia-Wen Wang, Fang Zheng, Bao-Xin Liu","doi":"10.1186/s12891-025-08881-9","DOIUrl":"10.1186/s12891-025-08881-9","url":null,"abstract":"<p><strong>Background: </strong>Ankle sprain is one of the common traumatic injuries in daily life, and PRICE (protection, rest, ice, compression pressure bandaging, elevation of the affected limb) principle is routinely recommended at its early stage. In traditional Chinese medicine (TCM), bone-setting technique (BST) can quickly relieve ankle pain and improve walking function, but physicians require high skills and physical strength. In this study, we designed an exercise-heel kicking exercise (HKE) based on the principles and methods of BST. This study aims to observe its true efficacy and safety.</p><p><strong>Methods: </strong>68 patients (18-45 years old) with grade I and II lateral ankle sprain within 48 h were recruited from TCM hospital affiliated to Guangzhou medical university and 60 cases meeting the criteria were enrolled and randomized into control group and intervention group (30 cases separately). The patients in both groups were treated with the PRICE and ankle pump exercise, and the ones in intervention group added heel kicking exercise (HKE). The visual analogue scale (VAS) for pain, swelling degree, and American orthopedic foot & ankle society ankle-hindfoot scale (AOFAS) score before and after the intervention (within 4 W), and Karlsson score (the 26th week follow-up) were measured.</p><p><strong>Results: </strong>Before treatment, there were no significant differences in VAS scores, swelling degrees and AOFAS scores between two groups. During the treatment for 4 weeks, VAS scores and swelling degrees of the patients in both groups gradually decreased, and the AOFAS score gradually increased (p < 0.01). In addition, patients in the intervention group were observed to get a quicker pain reliever, swelling subsiding, and ankle function restore than those in control group at most of time points of observation (1st d, 3rd d, 1st w, 2nd w, 4th w) (p < 0.05, p < 0.01). But there was no significant difference in Karlsson scores between two groups at the 26th week follow-up.</p><p><strong>Conclusions: </strong>HKE is a method designed to provide rapid movement rehabilitation for patients with ankle sprains, which can be used as one of its basic treatments.</p><p><strong>Trial registration: </strong>This study was registered in China Clinical Trial Center (NO. ChiCTR2300073709). Trial registration date: August 16th 2022.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"666"},"PeriodicalIF":2.2,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dina Hamed-Hamed, Celia Rodríguez-Pérez, Leo Pruimboom, Santiago Navarro-Ledesma
{"title":"Correction: Influence of the metabolic and inflammatory profile in patients with frozen shoulder - systematic review and meta‑analysis.","authors":"Dina Hamed-Hamed, Celia Rodríguez-Pérez, Leo Pruimboom, Santiago Navarro-Ledesma","doi":"10.1186/s12891-025-08905-4","DOIUrl":"10.1186/s12891-025-08905-4","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"664"},"PeriodicalIF":2.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early diagnosis and treatment of low-grade myofibroblastic sarcoma in the left distal femur: a case report and literature review.","authors":"Xinyu Hu, Yichen Gong, Zhongyi Zhang, Zhipeng Wu, Peijian Tong, Yan Liu, Shuaijie Lv","doi":"10.1186/s12891-025-08565-4","DOIUrl":"10.1186/s12891-025-08565-4","url":null,"abstract":"<p><strong>Background: </strong>Low-grade myofibroblastic sarcoma (LGMS) is a rare malignant tumor with a predilection for soft tissue and bone. This is a rare malignant tumor with diagnostic challenges, often leading to misdiagnosis as other similar diseases. As a result, its exact incidence remains unclear. While pathologic studies have been reported, systematic clinical, radiological, and therapeutic evaluations remain limited.</p><p><strong>Methods: </strong>This study presented a case of LGMS located in the left distal femur treated with distal femoral resection and total knee arthroplasty using a tumor knee joint system. A review of 24 published cases was conducted for comparative analysis, focusing on clinical presentations, radiological features, immunohistochemical findings, treatment strategies, and long-term outcomes.</p><p><strong>Results: </strong>Radiological analysis revealed a tumor confined to the distal femoral medullary cavity without cortical destruction or lytic changes. Immunohistochemical staining demonstrated: SMA (+), p53 (+), Ki-67 (30% +), CD163 (+), and CD68 (+), confirming the diagnosis of LGMS. Postoperatively, the patient reported significant pain relief and functional recovery at five months, with VAS, WOMAC, and HSS scores indicating improved joint function. The literature review highlighted LGMS's predilection for local recurrence, emphasizing the importance of early diagnosis and surgical intervention.</p><p><strong>Conclusion: </strong>LGMS demonstrates unique radiological and pathological features depending on its site of origin. Our case underscores the utility of wide excision and TKA in managing bone-involved LGMS. Further studies are needed to evaluate long-term outcomes and optimize management strategies.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"662"},"PeriodicalIF":2.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tao Jiang, Yubo Pan, Jianing Xu, Junyong Ge, Shiliang Ji, Tian Li, Yinquan Zhang
{"title":"Association between serum phosphorus levels and pelvic bone mineral density in U.S. adults aged 18-59 years.","authors":"Tao Jiang, Yubo Pan, Jianing Xu, Junyong Ge, Shiliang Ji, Tian Li, Yinquan Zhang","doi":"10.1186/s12891-025-08838-y","DOIUrl":"10.1186/s12891-025-08838-y","url":null,"abstract":"<p><strong>Background: </strong>Although the role of serum phosphorus in bone metabolism is well-established, its precise connection to bone density in different anatomical regions remains uncertain. The pelvis, a vital load-bearing structure crucial for movement and stability, has received limited attention because of its relationship with serum phosphorus. This study investigated the potential association between serum phosphorus levels and pelvic bone mineral density (BMD) in adults aged 18 to 59 years.</p><p><strong>Methods: </strong>Using data from the 2015-2018 National Health and Nutrition Examination Surveys NHANES, we applied multivariable logistic regression models to investigate the association between serum phosphorus levels and pelvic BMD. The analysis was further refined using smoothed curves and generalized additive models.</p><p><strong>Results: </strong>The analysis included a total of 5,589 adults. After adjusting for confounding variables, a negative association was observed between serum phosphorus levels and pelvic BMD. This inverse association was consistent in the subgroup analyses for females and Whites, however, this correlation was not found in males, Blacks, Mexican Americans, other Hispanics, or other racial groups.</p><p><strong>Conclusion: </strong>Our findings indicated a notable inverse association between serum phosphorus levels and pelvic bone mineral density in females, while no significant association was observed in males.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"665"},"PeriodicalIF":2.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vikrant Piprode, Shubhanath Behera, Juilee Karhade, Suhas T Mhaske, Mohan R Wani
{"title":"Priming of mouse pre-osteoblasts with Interleukin-3 attenuates TNF-α-induced-inhibition of osteoblast differentiation.","authors":"Vikrant Piprode, Shubhanath Behera, Juilee Karhade, Suhas T Mhaske, Mohan R Wani","doi":"10.1186/s12891-025-08610-2","DOIUrl":"10.1186/s12891-025-08610-2","url":null,"abstract":"<p><strong>Background: </strong>In inflammatory bone loss disorders, such as rheumatoid arthritis and post-menopausal osteoporosis, TNF-α is an important effector cytokine that promotes osteoclastogenesis and inhibits osteoblastogenesis. Currently, clinical interventions primarily include anti-osteoclastic agents to prevent bone loss, however, anabolic agents are scarce and there's an utmost need. Previously, IL- 3 has been shown to enhance osteogenic differentiation of human bone marrow-derived mesenchymal stem cells in vitro. However, its role remains unclear in inflammatory pathologies, where TNF-α negatively impacts osteoblast differentiation. This study aims to investigate IL- 3's impact on osteogenic differentiation process under the negative influence of TNF-α.</p><p><strong>Methods: </strong>Calvarial pre-osteoblasts were isolated from BALB/c mice pups and in vitro osteoblast differentiation was performed as per established protocols. TNF-α was used as a negative regulator of osteoblast differentiation and the effect of IL- 3 on this differentiation was studied by assessing matrix mineralization using Alizarin red S staining. Osteoblast differentiation markers, including, alkaline phosphatase and osteocalcin were evaluated using qPCR. ALP activity was measured using the pNPP colorimetric assay. Furthermore, Western blotting was employed to deduce the mechanism(s) of IL- 3 action on TNF-α-induced-inhibition of osteoblast differentiation.</p><p><strong>Results: </strong>Alizarin red S staining revealed that IL- 3 priming protects pre-osteoblasts from TNF-α-induced-inhibition of osteoblast differentiation and that this protective effect is irreversible. Mechanistically, IL- 3 pretreatment suppresses TNF- α-induced activation of NF-κB/SMURF1 axis thus preventing β-CATENIN degradation, which drives osteogenic gene expression.</p><p><strong>Conclusions: </strong>Priming mouse pre-osteoblasts with IL- 3 prevents TNF-α-induced of osteoblast differentiation in vitro, and, thus, could be a novel candidate in the treatment of inflammatory bone loss disorders.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"663"},"PeriodicalIF":2.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kai Zheng, Xiuchun Yu, Ming Xu, Haocheng Cui, Wenqiang Xing, Qian Chen
{"title":"Microwave ablation combined with curettage for low-grade chondrosarcomas in the extremities: a single-center study.","authors":"Kai Zheng, Xiuchun Yu, Ming Xu, Haocheng Cui, Wenqiang Xing, Qian Chen","doi":"10.1186/s12891-025-08787-6","DOIUrl":"10.1186/s12891-025-08787-6","url":null,"abstract":"<p><strong>Background: </strong>The surgical treatment of low-grade chondrosarcoma in the extremities remains a topic of controversy. This study aims to evaluate the clinical efficacy of microwave ablation combined with curettage in treating low-grade chondrosarcoma of the limbs.</p><p><strong>Methods: </strong>We analyzed data from 17 patients who underwent microwave ablation for low-grade chondrosarcoma of the extremities over the past decade. Results were assessed based on general condition, surgical complications, local disease control, and functional outcomes as measured by the Musculoskeletal Tumor Society (MSTS) 93 scoring system.</p><p><strong>Results: </strong>Among the 17 cases of low-grade chondrosarcoma, the distribution included 8 in the humerus, 7 in the femur, and 2 in the fibula. The median maximum diameter of the tumors was 5.5 cm (range: 4.0-8.2 cm), with a median follow-up of 53 months (range: 19-128 months). No patients required blood transfusions or experienced perioperative complications. The median surgical duration was 130 min (range: 60-150 min), and the average hospital stay was 7.9 days (range: 6-11 days). No local tumor recurrence or distant metastasis was observed during follow-up. Most patients reported minimal postoperative impact on limb functionality, with a median MSTS score of 28 (range: 20-30). Two patients sustained fractures; one underwent secondary internal fixation surgery and healed, while the other, with an asymptomatic microfracture, was monitored conservatively.</p><p><strong>Conclusions: </strong>Microwave ablation combined with curettage is a viable option for local control in the treatment of low-grade chondrosarcoma in the extremities.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"660"},"PeriodicalIF":2.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maarten R Huizinga, A J de Vries, T M van Raaij, R W Brouwer
{"title":"Radiological and clinical outcomes of combined wedge versus lateral closing wedge high tibial osteotomy for medial osteoarthritis of the knee: a randomized controlled trial.","authors":"Maarten R Huizinga, A J de Vries, T M van Raaij, R W Brouwer","doi":"10.1186/s12891-025-08896-2","DOIUrl":"10.1186/s12891-025-08896-2","url":null,"abstract":"","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"661"},"PeriodicalIF":2.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Internal fixation of comminuted patellar fractures with only non-absorbable suture via nice knot: a retrospective study.","authors":"Lian Zeng, Tian Xia, Xinyue Yang, Qiankun Xu, Yudong Sun, Chengfeng Li, Hongwei Lu, Wenzhe Sun, Peiran Xue, Pengqing Zhang, Jianwen Wang, Yanzhen Qu","doi":"10.1186/s12891-025-08913-4","DOIUrl":"10.1186/s12891-025-08913-4","url":null,"abstract":"<p><strong>Background: </strong>Due to the patella's thin overlying skin, metal implants frequently cause local discomfort that necessitates removal. This study aimed to evaluate the intraoperative and early postoperative outcomes of treating comminuted patellar fractures using non-absorbable sutures as the sole internal fixation method via the Nice knot technique.</p><p><strong>Methods: </strong>This retrospective study reviewed 25 patients with unilateral closed comminuted patellar fractures who underwent open reduction and internal fixation using either non-absorbable sutures tied with a Nice knot (NK group, n = 12) or the traditional tension band technique (TB group, n = 13). Intraoperative surgical time and blood loss were recorded. Postoperative clinical outcomes were evaluated using the Visual Analogue Scale (VAS) for pain, knee range of motion (ROM), and the Böstman scoring system. Radiographic assessments were conducted to evaluate fracture healing. Complications, including infection, implant loosening, and discomfort or irritation, were also documented.</p><p><strong>Results: </strong>Although the intraoperative surgical time was slightly longer in the NK group compared to the TB group, the difference was not statistically significant. The difference in blood loss between the NK and TB groups was also not statistically significant. No cases of bone non-union, implant loosening, or internal fixation failure were observed in either group during the follow-up period. One patient in the TB group developed a wound infection one week postoperatively. At the final follow-up, there were no significant differences between the two groups in terms of VAS scores, knee range of motion (ROM), or Böstman scores. However, in the TB group, five patients reported notable discomfort or irritation caused by the internal fixation.</p><p><strong>Conclusion: </strong>Compared with traditional tension band fixation, the Nice knot technique reduces soft tissue irritation, avoids implant removal surgery, potentially lowers postoperative infection rates, and achieves comparable fracture healing time and knee function. However, broader validation through multi-center studies is required.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"656"},"PeriodicalIF":2.2,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proximal lateral entry technique for the treatment of supracondylar humeral fractures in children and intraoperative nerve protection: a novel technique.","authors":"Bufeng Zheng, Wenyu Feng, Lei Geng, Kun Jiang","doi":"10.1186/s12891-025-08909-0","DOIUrl":"10.1186/s12891-025-08909-0","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the clinical outcomes of the proximal lateral-entry pinning technique in the treatment of supracondylar humeral fractures and to explore its performance in terms of intraoperative nerve protection.</p><p><strong>Methods: </strong>This retrospective analysis involved data from pediatric patients with supracondylar humeral fractures who were admitted to the Department of Pediatric Surgery at Binzhou Medical University Hospital between September 2017 and November 2023. A total of 342 patients were included and divided into two groups: Group P (proximal lateral-entry pinning) and Group C (conventional lateral condyle pinning). All patients were followed up for at least 6 months postoperatively. Baseline characteristics, the interval from injury to surgery, the operative time, the fracture healing status, and the timing of Kirschner wire removal were recorded. Elbow function was assessed using Flynn's functional and cosmetic criteria. Statistical comparisons were conducted using the Mann-Whitney U test, independent samples t-test, chi-square test, or Fisher's exact test, as appropriate. Complications such as loss of reduction, elbow deformity, vascular injury, iatrogenic nerve injury, and pin-tract infection were also documented.</p><p><strong>Results: </strong>There were no statistically significant differences in sex, body weight, age at injury, fracture laterality, anesthesia type, or waiting time from injury to surgery between the two groups (P > 0.05). Additionally, the operative time and timing of Kirschner wire removal did not differ significantly between the groups (P > 0.05). At the final follow-up, the proportion of patients with excellent/good elbow function in Group P was 99.42%, which was significantly greater than the proportion of 94.64% observed in Group C (P < 0.05). No radial or ulnar nerve injuries were reported in either group. Three cases of pin-tract infection occurred in Group P, and seven cases occurred in Group C (P > 0.05). Loss of reduction occurred in three cases in Group P and11 in Group C (P > 0.05). No incidences of elbow deformity or iatrogenic vascular injury were noted.</p><p><strong>Conclusion: </strong>The proximal lateral-entry pinning technique yields favorable fracture outcomes and does not increase the risk of radial or ulnar nerve injury when it is performed meticulously. This approach is therefore recommended as a viable surgical technique for treating supracondylar humeral fractures in children.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"658"},"PeriodicalIF":2.2,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}