微波消融联合刮除治疗四肢低级别软骨肉瘤:单中心研究

IF 2.2 3区 医学 Q2 ORTHOPEDICS
Kai Zheng, Xiuchun Yu, Ming Xu, Haocheng Cui, Wenqiang Xing, Qian Chen
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引用次数: 0

摘要

背景:下肢低级别软骨肉瘤的手术治疗仍然是一个有争议的话题。本研究旨在探讨微波消融联合刮刮术治疗下肢低级别软骨肉瘤的临床疗效。方法:我们分析了过去十年中接受微波消融治疗下肢低级别软骨肉瘤的17例患者的资料。结果是根据一般情况、手术并发症、局部疾病控制和肌肉骨骼肿瘤学会(MSTS) 93评分系统测量的功能结果来评估的。结果:17例低级别软骨肉瘤中,分布于肱骨8例,股骨7例,腓骨2例。肿瘤中位最大直径为5.5 cm(范围:4.0 ~ 8.2 cm),中位随访53个月(范围:19 ~ 128个月)。无患者需要输血或出现围手术期并发症。手术时间中位数为130分钟(范围:60-150分钟),平均住院时间7.9天(范围:6-11天)。随访期间未见肿瘤局部复发或远处转移。大多数患者报告术后对肢体功能的影响最小,MSTS中位评分为28(范围:20-30)。2例骨折;一名患者接受了二次内固定手术并愈合,而另一名无症状微骨折患者接受了保守监测。结论:微波消融联合刮除是治疗下肢低级别软骨肉瘤的一种可行的局部控制方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microwave ablation combined with curettage for low-grade chondrosarcomas in the extremities: a single-center study.

Background: The surgical treatment of low-grade chondrosarcoma in the extremities remains a topic of controversy. This study aims to evaluate the clinical efficacy of microwave ablation combined with curettage in treating low-grade chondrosarcoma of the limbs.

Methods: We analyzed data from 17 patients who underwent microwave ablation for low-grade chondrosarcoma of the extremities over the past decade. Results were assessed based on general condition, surgical complications, local disease control, and functional outcomes as measured by the Musculoskeletal Tumor Society (MSTS) 93 scoring system.

Results: Among the 17 cases of low-grade chondrosarcoma, the distribution included 8 in the humerus, 7 in the femur, and 2 in the fibula. The median maximum diameter of the tumors was 5.5 cm (range: 4.0-8.2 cm), with a median follow-up of 53 months (range: 19-128 months). No patients required blood transfusions or experienced perioperative complications. The median surgical duration was 130 min (range: 60-150 min), and the average hospital stay was 7.9 days (range: 6-11 days). No local tumor recurrence or distant metastasis was observed during follow-up. Most patients reported minimal postoperative impact on limb functionality, with a median MSTS score of 28 (range: 20-30). Two patients sustained fractures; one underwent secondary internal fixation surgery and healed, while the other, with an asymptomatic microfracture, was monitored conservatively.

Conclusions: Microwave ablation combined with curettage is a viable option for local control in the treatment of low-grade chondrosarcoma in the extremities.

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来源期刊
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders 医学-风湿病学
CiteScore
3.80
自引率
8.70%
发文量
1017
审稿时长
3-6 weeks
期刊介绍: BMC Musculoskeletal Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of musculoskeletal disorders, as well as related molecular genetics, pathophysiology, and epidemiology. The scope of the Journal covers research into rheumatic diseases where the primary focus relates specifically to a component(s) of the musculoskeletal system.
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