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Inhaled sedation versus intravenous sedation in critically ill patients (IS-CRITIC): protocol for a multicentre, randomised, controlled clinical trial in Spain. 危重患者吸入镇静与静脉镇静（IS-CRITIC）：西班牙一项多中心随机对照临床试验方案
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2026-123745
José Manuel Añón, Andoni García-Muñoz, María Paz Escuela, José Manuel Gómez-García, Manuel Pérez Torres, Arís Pérez-Lucendo, Ana María Prieto, Sofía Contreras, Eva Benveniste, Mónica García-Simón, Oriol Plans-Galván, Eugenia Graciani-Cantisan, Covadonga Rodríguez-Ruiz, Alexander Agrifoglio, Gloria Gonzalo, Laura Macaya, Begoña Bueno, Arturo Rodríguez-Pérez, Marta Martín-Muñoz, Sara Alcántara, Rocío Prieto-Pérez, Mariana Díaz Almirón
{"title":"Inhaled sedation versus intravenous sedation in critically ill patients (IS-CRITIC): protocol for a multicentre, randomised, controlled clinical trial in Spain.","authors":"José Manuel Añón, Andoni García-Muñoz, María Paz Escuela, José Manuel Gómez-García, Manuel Pérez Torres, Arís Pérez-Lucendo, Ana María Prieto, Sofía Contreras, Eva Benveniste, Mónica García-Simón, Oriol Plans-Galván, Eugenia Graciani-Cantisan, Covadonga Rodríguez-Ruiz, Alexander Agrifoglio, Gloria Gonzalo, Laura Macaya, Begoña Bueno, Arturo Rodríguez-Pérez, Marta Martín-Muñoz, Sara Alcántara, Rocío Prieto-Pérez, Mariana Díaz Almirón","doi":"10.1136/bmjopen-2026-123745","DOIUrl":"https://doi.org/10.1136/bmjopen-2026-123745","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e123745"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient acceptance of preventive antibiotic treatment for tuberculosis: a qualitative study in London, UK. 结核病患者接受预防性抗生素治疗：英国伦敦的一项定性研究。
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2026-126587
Mélanie Antunes, Rubin Rose-Key, Ellen Steward, Sammy Assayad, Mahdad Noursadeghi, Luis Enrique Loría-Rebolledo, Elisa Crayton, Rishi Gupta
{"title":"Patient acceptance of preventive antibiotic treatment for tuberculosis: a qualitative study in London, UK.","authors":"Mélanie Antunes, Rubin Rose-Key, Ellen Steward, Sammy Assayad, Mahdad Noursadeghi, Luis Enrique Loría-Rebolledo, Elisa Crayton, Rishi Gupta","doi":"10.1136/bmjopen-2026-126587","DOIUrl":"https://doi.org/10.1136/bmjopen-2026-126587","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e126587"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How do support networks influence physical activity participation among adults with a learning disability? A scoping review protocol. 支持网络如何影响有学习障碍的成年人参与体育活动？范围审查协议。
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2026-117713
Ellie Rossiter, Anna Pettican, Paul Freeman, James Black, Simone Coetzee, Ewen Speed
{"title":"How do support networks influence physical activity participation among adults with a learning disability? A scoping review protocol.","authors":"Ellie Rossiter, Anna Pettican, Paul Freeman, James Black, Simone Coetzee, Ewen Speed","doi":"10.1136/bmjopen-2026-117713","DOIUrl":"https://doi.org/10.1136/bmjopen-2026-117713","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e117713"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
General practitioners' capability, opportunity and motivation to discuss physical activity at the 6-8 week postnatal check in the UK: a qualitative study using the COM-B model. 在英国，全科医生在产后6-8周检查时讨论身体活动的能力、机会和动机：一项使用COM-B模型的定性研究。
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2026-122011
Joseph Morwood, Peter C Rouse, Marlize De Vivo
{"title":"General practitioners' capability, opportunity and motivation to discuss physical activity at the 6-8 week postnatal check in the UK: a qualitative study using the COM-B model.","authors":"Joseph Morwood, Peter C Rouse, Marlize De Vivo","doi":"10.1136/bmjopen-2026-122011","DOIUrl":"https://doi.org/10.1136/bmjopen-2026-122011","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e122011"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double-blind, placebo-controlled randomised clinical trial on flexible doses of escitalopram and naltrexone in the treatment of men with compulsive sexual behaviour disorder: study protocol presentation. 双盲，安慰剂对照随机临床试验，灵活剂量的艾司西酞普兰和纳曲酮治疗男性强迫性性行为障碍：研究方案介绍。
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2026-125612
Michał Lew-Starowicz, Małgorzata Draps, Kacper Wilk, Pawel Wisniewski, Mateusz Gola
{"title":"Double-blind, placebo-controlled randomised clinical trial on flexible doses of escitalopram and naltrexone in the treatment of men with compulsive sexual behaviour disorder: study protocol presentation.","authors":"Michał Lew-Starowicz, Małgorzata Draps, Kacper Wilk, Pawel Wisniewski, Mateusz Gola","doi":"10.1136/bmjopen-2026-125612","DOIUrl":"https://doi.org/10.1136/bmjopen-2026-125612","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e125612"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Community health and well-being workers (CHWWs) for preventive healthcare services uptake in the UK: a cluster-randomised controlled trial protocol. 社区卫生和福利工作者（CHWWs）预防保健服务的吸收在英国：一个集群随机对照试验协议。
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2026-124582
Rawan Gadi, Cornelia Junghans Minton, Ahmad Alkhatib, Thomas Woodcock, David Peiris, Otavio Berwanger, Laurent Billot, Matthew Harris
{"title":"Community health and well-being workers (CHWWs) for preventive healthcare services uptake in the UK: a cluster-randomised controlled trial protocol.","authors":"Rawan Gadi, Cornelia Junghans Minton, Ahmad Alkhatib, Thomas Woodcock, David Peiris, Otavio Berwanger, Laurent Billot, Matthew Harris","doi":"10.1136/bmjopen-2026-124582","DOIUrl":"https://doi.org/10.1136/bmjopen-2026-124582","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e124582"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can maternal characteristics improve due date prediction without ultrasound? Development and internal validation of a machine-learning prediction model in 600 000 pregnancies in Sweden. 产妇特征能改善预产期预测吗？瑞典60万例怀孕的机器学习预测模型的开发和内部验证。
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2026-120970
Gilson Dutra, Mikael Elinder, Oscar Erixson
{"title":"Can maternal characteristics improve due date prediction without ultrasound? Development and internal validation of a machine-learning prediction model in 600 000 pregnancies in Sweden.","authors":"Gilson Dutra, Mikael Elinder, Oscar Erixson","doi":"10.1136/bmjopen-2026-120970","DOIUrl":"https://doi.org/10.1136/bmjopen-2026-120970","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e120970"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149242997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of double plasma cytokine adsorption system with sequential low-volume plasma exchange in treating acute-on-chronic liver failure complicated by sepsis: protocol for a multicentre randomised controlled clinical trial. 双血浆细胞因子吸附系统与序贯低容量血浆交换治疗急慢性肝衰竭合并脓毒症的疗效和安全性：一项多中心随机对照临床试验方案
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2025-115807
Jia Chen, Yihua Pang, Lina Wu, Lili Li, Lihua Zheng, Shan Ouyang, Xiyao Chen, Yuankai Wu, Wenxiong Xu, Liang Peng
{"title":"Efficacy and safety of double plasma cytokine adsorption system with sequential low-volume plasma exchange in treating acute-on-chronic liver failure complicated by sepsis: protocol for a multicentre randomised controlled clinical trial.","authors":"Jia Chen, Yihua Pang, Lina Wu, Lili Li, Lihua Zheng, Shan Ouyang, Xiyao Chen, Yuankai Wu, Wenxiong Xu, Liang Peng","doi":"10.1136/bmjopen-2025-115807","DOIUrl":"https://doi.org/10.1136/bmjopen-2025-115807","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e115807"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of adherence intervention programmes for home exercises in stroke survivors: a systematic review of randomised controlled trials. 中风幸存者家庭锻炼依从性干预方案的有效性：随机对照试验的系统回顾。
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-23 DOI: 10.1136/bmjopen-2026-125860
Weiwei Guo, Kim Lam Soh, Hasni Idayu Saidi, Kim Geok Soh
{"title":"Effectiveness of adherence intervention programmes for home exercises in stroke survivors: a systematic review of randomised controlled trials.","authors":"Weiwei Guo, Kim Lam Soh, Hasni Idayu Saidi, Kim Geok Soh","doi":"10.1136/bmjopen-2026-125860","DOIUrl":"https://doi.org/10.1136/bmjopen-2026-125860","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e125860"},"PeriodicalIF":2.5,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility and acceptability of a remote blood pressure monitoring pharmacist-led telehealth programme in an emergency department transition care clinic: a pilot randomised controlled trial. 在急诊科过渡护理诊所实施远程血压监测药剂师主导的远程医疗方案的可行性和可接受性：一项试点随机对照试验。
IF 2.5 3区 医学
BMJ Open Pub Date : 2026-10-22 DOI: 10.1136/bmjopen-2026-121681
Lama Ghazi, Paulina Gonzalez-Flores, Emily Green Vance, Quinn H Short, Tapan Mehta, L R Hearld, Shoaib Mahmood, Javier A Neyra, M J Mugavero
{"title":"Feasibility and acceptability of a remote blood pressure monitoring pharmacist-led telehealth programme in an emergency department transition care clinic: a pilot randomised controlled trial.","authors":"Lama Ghazi, Paulina Gonzalez-Flores, Emily Green Vance, Quinn H Short, Tapan Mehta, L R Hearld, Shoaib Mahmood, Javier A Neyra, M J Mugavero","doi":"10.1136/bmjopen-2026-121681","DOIUrl":"10.1136/bmjopen-2026-121681","url":null,"abstract":"","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"16 10","pages":"e121681"},"PeriodicalIF":2.5,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13691778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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