Journal of integrative cardiology最新文献

{"title":"Socio-demographic profile, lifestyle changes and co-morbid ailments as predictors of medication adherence among hypertensive patients attending federal teaching hospital, ido-ekiti, southwestern, nigeria","authors":"A. Ibrahim, T. Agbesanwa, Adewumi Oluwaserimi Ajetunmobi, Fasanmi Tolulope Kolawole, Adebayo Fashola, M. Olanrewaju","doi":"10.15761/JIC.1000300","DOIUrl":"https://doi.org/10.15761/JIC.1000300","url":null,"abstract":"Background: Non-adherence to anti-hypertensive medications is a modifiable risk factor for uncontrolled hypertension. Despite the availability of tolerable anti- hypertensive drugs, majority of patients are still not adherent to their medications. Aim: To investigate Socio-demographic profile, lifestyle changes and comorbid ailments as predictors of medication Adherence among hypertensive patients attending Federal Teaching Hospital, Ido-Ekiti, Southwestern, Nigeria. Methods: Hospital-based cross-sectional study was conducted on 356 hypertensive patients on follow up. Systematic random sampling technique was adopted to recruit the 356 respondents. Semi-structured interviewer administered questionnaire was employed to seek information on respondents’ socio-demographic characteristics, lifestyle changes, comorbid ailments, and number of antihypertensive medications. Adherence level was determined using the Morisky’s Medication Adherence Scale. Data was analyzed using SPSS 20. Multivariate logistic regression analysis was used to identify the predictors of medication adherence. Results: The prevalence of medication adherence was 60.4%. In multivariate analysis; male gender (OR, 15.85, 95% CI: 4.33 – 58.11) level of education (OR, 16.94, 95% CI: 1.13 – 253.06) habits of salt usage (OR, 284, 95% CI: 29.35 – 2748.37) and two anti-hypertensive drugs (OR, 15.13, 95% CI: 4.78 – 47.867) were the predictors of good medication adherence. On the other hand, trading (OR, 0.13, 95% CI: 0.02 – 0.78) was associated with poor medication adherence. Conclusion: The prevalence of medication adherence was low. Trading was the predictor of poor medication adherence. Therefore, clinicians and other stakeholders should target this set of occupation and provide qualitative health education to improve their medication adherence level.","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67484371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombolytics, still the first therapeutic weapon against acute ST-segment elevation myocardial infarction","authors":"F. Benaim, Sebastian Raúl Fonseca, H. C. Arazi, M. Blanco, R. Ferreyra","doi":"10.15761/jic.1000287","DOIUrl":"https://doi.org/10.15761/jic.1000287","url":null,"abstract":"the First Therapeutic ABSTRACT Cardiovascular disease (CVD) is the leading cause of death worldwide, being coronary events the most common cause of CVD. In the case of an acute ST-segment elevation myocardial infarction, the conventional treatment involves the reperfusion of the culprit artery as soon as possible as angioplasty has replaced the thrombolysis therapy. We present two patients with acute ST-segment elevation myocardial infarction. The first patient showed an ST-segment elevation of the anterolateral wall, and the second one, in the inferolateral wall. In both cases we performed rapid reperfusion with thrombolytics (ischemic time less than 30 minutes), with good response. The first patient showed a lesion in the subendocardial myocardium in the late gadolinium enhancement in cardiovascular magnetic resonance imaging. Taking into account the time delays of patients-derivation and door-to-balloon time in developing countries, these cases reinforce the indication of thrombolytics as the treatment of choice.","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67483590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of ultrafiltration with the outcomes of cardiopulmonary bypass surgery in adults with cardiovascular disease: The result of a systematic review and meta-analysis","authors":"M. Al-Sadawi, Farzane Saeidifard, R. R. Ortega, P. Erwin, M. Abdallat, F. A. Hassan, A. Budzikowski","doi":"10.15761/JIC.1000293","DOIUrl":"https://doi.org/10.15761/JIC.1000293","url":null,"abstract":"Introduction: Previous studies have shown that ultrafiltration (UF) is associated with improved minor and major outcomes of cardiopulmonary bypass (CPB) by improving tissue perfusion as well as lowering the patient’s hematocrit and blood loss and finally reducing the mortality. This meta-analysis aimed to pool the data of the previous studies on the association between using UF in the perioperative period and clinical outcomes in adult patients undergoing CPB. Methods: We searched Ovid MEDLINE, Ovid Embase Scopus, Web of Science, Google Scholar, and EBSCO CINAHL from inception up to June 29th, 2019. The studies that assessed the association of UF with the outcomes of CPB in adults were eligible for inclusion. We did not restrict the search to time or language. Two independent investigators screened the identified studies and extracted the data in duplicate. We analyzed sixteen different clinical outcomes. Heterogeneity was assessed using Cochrane collaboration tools. Results: Primary search identified 1114 studies from which 22 studies with 8538 patients were found eligible for inclusion. Results showed a statistically significant reduction in perioperative bleeding (-107.59 (ml) CI [-179.01, -36.18]), red blood cell transfusion (-0.76 (unit/patient) CI [-1.02,-0.51]) and ICU length of stay (-0.16 (day) CI [-0.31,-0.01]) in the group with UF compared to the control group. Aortic cross-clamp time, CPB time, ventilation time, hospital length of stay, as well as number of myocardial infarctions, chest infection, perioperative arrhythmia, low cardiac output, stroke/TIA, acute renal failure, intra-aortic balloon pump, reoperation and mortality was not statistically different between the two groups (p=>0.05). Conclusion: Using UF in adult patients undergoing CPB is associated with reduced perioperative bleeding, red blood cell transfusion, and ICU length of stay. However, the use of UF was not associated with the reduction of major cardiovascular outcomes.","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67483844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results of SGLT2 inhibitor treatment in patients with Type 2 Diabetes mellitus and heart failure with reduced ejection fraction","authors":"Hatice Ozisik, Ş. Çetinkalp, A. Candemir, Asli Suner Karakülah, S. Nalbantgil","doi":"10.15761/JIC.1000296","DOIUrl":"https://doi.org/10.15761/JIC.1000296","url":null,"abstract":"Introduction: Type 2 diabetes mellitus (T2DM) incidence is increasing all over the world due to obesity. Heart failure (HF) occurs when the functional impairment develops in the myocardium. T2DM may concur with HF and cause its development. The excellent pleiotropic effects of SGLT2 inhibitors within the cardiovascular system make these drugs attractive for the treatment of diabetes in patients with HF. Materials and Methods: Our study population included 21 patients with New York Heart Association (NYHA) classification II to IV with an ejection fraction less than or equal to 40% and type 2 diabetes mellitus. They were enrolled between February 2019 and February 2020. We collected information on age, sex, eGFR, Left ventricular ejection fraction (LVEF) and duration of empagliflozin usage. Addition of once daily 10 mg of empagliflozin to their treatment applied. Results: 21 patients with NYHA classification II to IV with an ejection fraction less than or equal to 40% and type 2 diabetes mellitus were enrolled, 19 were male (90.5%). The mean age of the patients was 60 ± 7.21 (Male: 59.11 ± 7.15; Female: 57.50 ± 10.60). The mean use of empagliflozin was 6.90 ± 4.38 months. The mean LVEF in Ecocardiography was 30.52 ± 9.36%. The difference between pro BNP (p=0.205), total cholesterol (p=0.723), triglyceride (p=0.082), HDL (p=0.778), LDL (p=0.808), Hba1c (p=0.643) levels before and after empagliflozin treatment were not statistically significant (p>0.05). Discussion: Patients with type 2 diabetes and heart failure have been reported to have reduced levels of proBNP and Hba1c with SGLT2 inhibition. In addition, it reduces body weight, blood pressure, CV risk, HF hospitalization. However, in our study, such benefits were not observed in both laboratory and clinical parameters. Large number of patients are needed to research.","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67483732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic risk stratification enables primary prevention of CAD","authors":"R. Roberts, Chih Chao Chang","doi":"10.15761/JIC.1000298","DOIUrl":"https://doi.org/10.15761/JIC.1000298","url":null,"abstract":"Coronary artery disease accounts for one-third of all deaths in the world and it is estimated that 50% of the American population will have a cardiac event in a normal lifespan. Prevention of CAD has been successful, particularly for secondary prevention. Determining who is at risk for primary prevention based on traditional risk factors (TRFs) is inadequate because the TRFs are often not present until the 6 th or 7 th decade. Sensitivity based on TRFs is further compromised by the recent observation that early primary prevention, based on results of Mendelian Randomization Studies, is threefold more effective. Genetic risk stratification has been assessed in multiple studies involving over one million participants and found to be superior and complementary to methods based on TRS. The upper 20% of the genetic risk score exhibits one to threefold increased risk of CAD. Stratification based on the 10-year risk, as determined by the Pooled Cohort Equation in the current guidelines, would recommend only about 45% of these individuals to receive statin therapy. Results of randomized clinical trials show genetic risk is markedly reduced by statin therapy, lifestyle changes, and physical activity. Genetic risk score has a major advantage over risk stratification based on TRFs, since it is independent of age and provides the same risk at birth as anytime later in life since one’s DNA does not change in one’s lifetime. The test, performed on blood, saliva, or tissue, is inexpensive and is available throughout the world. Statin (those off-patent), the number one drug for prevention, is inexpensive and available worldwide. Genetic risk stratification will enable the implementation of primary prevention of CAD early in life throughout the world. risk score calculated from the genotyping, one can categorize the risk into high, intermediate, and low risk. Multiple studies indicate that the top 20% of genetic risk carries The at risk may vary with both","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67484243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The major approaches to prasugrel and ticagrelor in patients with acute coronary syndrome: state of the art","authors":"Maria C. V. B. Braile‐Sternieri, Victor Rodrigues Ribeiro Ferreira, Eliana Migliorini Mustafa, S. B. Sabino, G. B. Sternieri, Luiza Braile Verdi, Cibele Olegário Vianna Queiroz, Bethina Canaroli Sbardellini, I. J. Filho, D. Braile","doi":"10.15761/jic.1000288","DOIUrl":"https://doi.org/10.15761/jic.1000288","url":null,"abstract":"In the setting of the Acute Coronary Syndrome (ACS), Aspirin is recommended for all suspected patients, unless contraindicated. The addition of a second antiplatelet agent such as Clopidogrel, Ticagrelor or Prasugrel is also recommended for most patients. Parenteral anticoagulation is recommended with unfractionated heparin, low molecular weight heparin, Bivalirudin and Fondaparinux [1]. Proton pump inhibitors are recommended to prevent bleeding due to the use of antiplatelet agents and anticoagulation in patients with an aboveaverage risk of gastrointestinal bleeding. Other medical therapies should include statins, angiotensin-converting enzyme inhibitors, betablockers, nitroglycerin and morphine, and oxygen. For patients with ST-segment elevation myocardial infarction, percutaneous coronary intervention (PCI) with stent placement should be performed as soon as possible. However, fibrinolytic therapy should be used first if the PCI takes longer than 120 minutes.","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67483717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac rehabilitation in nigeria and its challenges","authors":"Edafe Emmanuel Auchi, A. Adebayo, Stanley Cn","doi":"10.15761/jic.1000284","DOIUrl":"https://doi.org/10.15761/jic.1000284","url":null,"abstract":"Cardiac Rehabilitation (CR) is a goal targeted program designed for the patient living with cardiovascular disease such as myocardial infarction, heart failure, valvular heart disease to have maximum benefits of self-depended and alleviate the disease condition. It improves morbidity and reduces mortality. In this review, our objective is to discuss the challenges of cardiac rehabilitation in Nigeria. *Correspondence to: Edafe Emmanuel Auchi, Department of Cardiology Unit, Bayelsa Specialist Hospital, Yenagoa, Nigeria, E-mail: dremmanueledafe@gmail.com","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67484000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitral insufficiency following electrical cardioversion in pediatric patients","authors":"Scaglione Jorge, M. Seminario, G. Schvartz","doi":"10.15761/JIC.1000297","DOIUrl":"https://doi.org/10.15761/JIC.1000297","url":null,"abstract":"Following electrical cardioversion, some adult patients with pre-existing atrial arrhythmias (usually atrial fibrillation) can present mitral insufficiency. However, to our knowledge, this effect has not been previously described in pediatric patients. In the present work, we report three cases of pediatric patients followed at our Hospital (Hospital de de Elizalde “Casa Cuna”, Buenos Aires, Argentina), who presented transient mitral insufficiency after electrical cardioversion.","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67483789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Takotsubo cardiomyopathy in an old man with multiple cardiovascular risk factors and chronic anxiety","authors":"Savarino Victória Pereira, A. Feijão, L. Rosário, H. Morais","doi":"10.15761/JIC.1000267","DOIUrl":"https://doi.org/10.15761/JIC.1000267","url":null,"abstract":"We describe a 75-year-old male, with several risk factors for coronary artery disease admitted for ST-segment elevation acute myocardial infarction. Unexpectedly, coronary angiography showed normal coronary arteries; left ventriculography revealed hypercontractility of the basal segments, ballooning of the medial and apical segments of the antero-lateral wall with ejection fraction of 40%, suggesting Takotsubo syndrome. Two-dimensional transthoracic echocardiography on admission confirmed the alterations of the segmental wall motion abnormality observed in left ventriculography. Repeated transthoracic echocardiogram revealed normalized left ventricular systolic function (ejection fraction of 62%) without any segmental wall motion abnormality. He was discharged at home with routine appointment. He remainders asymptomatic in sixth month follow up. *Correspondence to: Humberto Morais – Hospital Militar Principal/Instituto Superior Rua Pedro Miranda 40-42 Maianga Luanda República de Angola, E-mail: hmorais1@gmail.com","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67483462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Passive and Invasive CO2 Elimination via interventional Lung Assist System iLA [Novalung®] on a Small Intensive Care Unit of a Hospital for Basic and Regular Care","authors":"Kostov V, M. M., Stoerzbach S, Barth T, Clement R, Döffert J, Oberhoff M, Anger T","doi":"10.15761/jic.1000275","DOIUrl":"https://doi.org/10.15761/jic.1000275","url":null,"abstract":"","PeriodicalId":91545,"journal":{"name":"Journal of integrative cardiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67483108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}