Socio-demographic profile, lifestyle changes and co-morbid ailments as predictors of medication adherence among hypertensive patients attending federal teaching hospital, ido-ekiti, southwestern, nigeria

A. Ibrahim, T. Agbesanwa, Adewumi Oluwaserimi Ajetunmobi, Fasanmi Tolulope Kolawole, Adebayo Fashola, M. Olanrewaju
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Abstract

Background: Non-adherence to anti-hypertensive medications is a modifiable risk factor for uncontrolled hypertension. Despite the availability of tolerable anti- hypertensive drugs, majority of patients are still not adherent to their medications. Aim: To investigate Socio-demographic profile, lifestyle changes and comorbid ailments as predictors of medication Adherence among hypertensive patients attending Federal Teaching Hospital, Ido-Ekiti, Southwestern, Nigeria. Methods: Hospital-based cross-sectional study was conducted on 356 hypertensive patients on follow up. Systematic random sampling technique was adopted to recruit the 356 respondents. Semi-structured interviewer administered questionnaire was employed to seek information on respondents’ socio-demographic characteristics, lifestyle changes, comorbid ailments, and number of antihypertensive medications. Adherence level was determined using the Morisky’s Medication Adherence Scale. Data was analyzed using SPSS 20. Multivariate logistic regression analysis was used to identify the predictors of medication adherence. Results: The prevalence of medication adherence was 60.4%. In multivariate analysis; male gender (OR, 15.85, 95% CI: 4.33 – 58.11) level of education (OR, 16.94, 95% CI: 1.13 – 253.06) habits of salt usage (OR, 284, 95% CI: 29.35 – 2748.37) and two anti-hypertensive drugs (OR, 15.13, 95% CI: 4.78 – 47.867) were the predictors of good medication adherence. On the other hand, trading (OR, 0.13, 95% CI: 0.02 – 0.78) was associated with poor medication adherence. Conclusion: The prevalence of medication adherence was low. Trading was the predictor of poor medication adherence. Therefore, clinicians and other stakeholders should target this set of occupation and provide qualitative health education to improve their medication adherence level.
尼日利亚西南部ido-ekiti联邦教学医院高血压患者的社会人口特征、生活方式改变和合并症作为药物依从性的预测因素
背景:不坚持抗高血压药物治疗是高血压失控的一个可改变的危险因素。尽管有可耐受的降压药,但大多数患者仍不能坚持服药。目的:调查尼日利亚西南部Ido-Ekiti联邦教学医院高血压患者的社会人口特征、生活方式改变和合并症作为药物依从性的预测因素。方法:对356例高血压患者进行横断面随访研究。采用系统随机抽样方法,共调查356人。采用半结构式问卷调查,了解调查对象的社会人口特征、生活方式改变、合并症、降压药数量等信息。依从性水平采用莫里斯基药物依从性量表测定。数据采用SPSS 20进行分析。采用多因素logistic回归分析确定药物依从性的预测因素。结果:患者服药依从率为60.4%。在多元分析中;男性性别(OR, 15.85, 95% CI: 4.33 ~ 58.11)、文化程度(OR, 16.94, 95% CI: 1.13 ~ 253.06)、盐的使用习惯(OR, 284, 95% CI: 29.35 ~ 2748.37)和两种抗高血压药物(OR, 15.13, 95% CI: 4.78 ~ 47.867)是良好药物依从性的预测因素。另一方面,交易(OR, 0.13, 95% CI: 0.02 - 0.78)与药物依从性差相关。结论:患者服药依从性较低。交易是药物依从性差的预测指标。因此,临床医生和其他利益相关者应该针对这组职业,提供定性的健康教育,以提高他们的药物依从性水平。
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