BMC Rheumatology最新文献

{"title":"Prevalence of effective contraceptive use among patients with rheumatic diseases: a descriptive study.","authors":"Mayalen Uthurriague, Charlotte Delattre, Thomas Barnetche, Estibaliz Lazaro, Marie-Elise Truchetet, Claude Hocke, Nadia Mehsen-Cetre, Valérie Bernard, Christophe Richez","doi":"10.1186/s41927-026-00616-0","DOIUrl":"10.1186/s41927-026-00616-0","url":null,"abstract":"","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12997836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146177843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital interactions with the pharmaceutical industry: a qualitative focus group study on the perspectives of rheumatology care providers in Germany.","authors":"Susann May, Amina Jeleskovic-Öztürk, Hannah Meisberger, Finnja Stangel, Katharina Boy, Niklas Ohm, Greta Nordmann, Robert Darkow, Johannes Knitza, Felix Muehlensiepen","doi":"10.1186/s41927-026-00623-1","DOIUrl":"10.1186/s41927-026-00623-1","url":null,"abstract":"","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12998326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146164171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preferences, experiences and needs regarding tobacco cessation expressed among patients with rheumatoid arthritis: a qualitative study.","authors":"Maria A Lopez-Olivo, Sheneze Madramootoo, Johncy J Kachira, Kaleb Michaud, Rebecca Schumacher, Paul Cinciripini, Maria E Suarez-Almazor","doi":"10.1186/s41927-026-00622-2","DOIUrl":"10.1186/s41927-026-00622-2","url":null,"abstract":"","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12990605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146156068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NRAS and SREBF1 identified as mitophagy-associated risk genes for rheumatoid arthritis through interpretable machine learning and experimental validation studies.","authors":"Hongman Li, Peng Liu, Xiao Han, Shengyong Si, ZhiJing Li, Chun Zhao, Xue Zhao, Xue Zhou, Mengdie Liu","doi":"10.1186/s41927-026-00620-4","DOIUrl":"10.1186/s41927-026-00620-4","url":null,"abstract":"","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12977777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient satisfaction in a new model of nurse- and pharmacist-led virtual monitoring clinic in rheumatology practice.","authors":"Cheryl Y L Lim, Shuo Chen, Siaw Ing Yeo, Andrea H L Low, Warren Fong, Li-Ching Chew, Cassandra Hong, Chin Teck Ng, Yih Jia Poh, Tze Chin Tan, Sow Ling Yee, Teong Guan Lim, Cynthia S Q Ong, Ying-Ying Leung","doi":"10.1186/s41927-026-00615-1","DOIUrl":"10.1186/s41927-026-00615-1","url":null,"abstract":"","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12964925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146117747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world effectiveness and safety of upadacitinib in Japanese patients with rheumatoid arthritis: impact of age, renal function, and low-dose therapy.","authors":"Yuto Tanno, Naoki Kondo, Satoshi Ito, Yoko Wada, Takeshi Kuroda, Eriko Hasegawa, Daisuke Kobayashi, Suguru Yamamoto","doi":"10.1186/s41927-026-00621-3","DOIUrl":"10.1186/s41927-026-00621-3","url":null,"abstract":"","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12955292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported depression on the Lupus Impact Tracker questionnaire (LIT) is associated with glucocorticoid use and fibromyalgia in systemic lupus erythematosus, according to RELESSER-PROS registry data.","authors":"Inigo Rua-Figueroa, Julia Martínez-Barrio, Zulema Plaza, Norman Jiménez, Maria Galindo-Izquierdo, Esther Uriarte, Antonio Fernandez-Nebro, Jaime Calvo Alen, José Rosas, Javier Narváez, Elena Aurrecoechea, Mercedes Freire, Eva Tomero, Clara Sanguesa, Carlota Iniguez, Ana Perez, Sandra Garrote, Nuria Lozano-Rivas, Oihane Ibarguengoitia, Eva Salgado, Celia Erausquin, Tarek Carlos Salman Monte, Raúl Menor, Irene Altabás-González, Jorge Fragio Gil, Joan M Nolla, Jose M Pego-Reigosa","doi":"10.1186/s41927-025-00612-w","DOIUrl":"10.1186/s41927-025-00612-w","url":null,"abstract":"","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":"17"},"PeriodicalIF":2.5,"publicationDate":"2026-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12911092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146043817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-bariatric surgery-associated inflammatory arthritis: a case series describing clinical and MRI features.","authors":"Jehat Kiliç, Gülşah Yamancan, Yusuf Doğan, Sümeyye Şahin, Burak Öz, Ahmet Karataş, Süleyman Serdar Koca","doi":"10.1186/s41927-026-00619-x","DOIUrl":"10.1186/s41927-026-00619-x","url":null,"abstract":"","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":"16"},"PeriodicalIF":2.5,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12911282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related quality of life among people with rheumatic and musculoskeletal diseases in Cyprus: a cross-sectional study of disease burden and time since diagnosis.","authors":"Nikoleta Nikolaou, Victor Hadjiroussos, Christiana Nicolaou, Michalis Michaelides, Andrie G Panayiotou, Nicos Middleton","doi":"10.1186/s41927-026-00617-z","DOIUrl":"10.1186/s41927-026-00617-z","url":null,"abstract":"<p><strong>Background: </strong>Rheumatic and musculoskeletal diseases (RMDs) profoundly affect health-related quality of life (HRQoL), imposing a significant distinct burden on physical and mental well-being. Given the high prevalence and long-term disability associated with RMDs, understanding their impact is essential for informing public health priorities. This study aims to delineate the multifaceted impact of RMDs on HRQoL across diverse disease categories and examine how the impact on HRQoL varies by diagnosis and time since diagnosis.</p><p><strong>Methods: </strong>This cross-sectional study (July 2023 - July 2024) employed a mixed sampling approach, combining a stratified sample of participants from clinical settings with an open call through online channels to reach a broader population of individuals with RMD in Cyprus. Physical (PCS) and Mental Component Scores (MCS) of the SF-12 questionnaire were used to assess HRQoL. Demographic and clinical variables, including age, gender, marital status, smoking status, and time since diagnosis were recorded. Multivariable regression analyses were used to explore differences in HRQoL scores by disease group and time since diagnosis, adjusting for demographic characteristics.</p><p><strong>Results: </strong>The study enrolled 789 participants (mean age 55.4 ± 13.2 years, 76.6% female). Among participants, 57.4% reported low PCS (< 40) and 38.7% reported low MCS (< 40). Fibromyalgia demonstrated the most pronounced HRQoL impairments, with significantly lower scores, compared to inflammatory diseases, for both physical (B = - 11.45; 95% CI: - 15.06, - 7.83) as well as mental components of HRQoL (B = - 12.31; 95% CI: - 16.18, - 8.4). Notable reductions in PCS and MCS were also recorded among patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) reflecting the systemic and psychological burden of these conditions. Marked HRQoL reductions were recorded among participants in early disease stages (0-2 years), while those with a longer time since diagnosis (2-10 years) demonstrated relative improvements.</p><p><strong>Conclusion: </strong>RMDs significantly impact HRQoL, with substantial variability across disease categories and time since diagnosis. While the cross-sectional nature of the study does not capture trajectories across stages of disease progression, the significant and differential by disease category impairment in HRQoL at the early stages emphasize the need for disease-specific, multidisciplinary care approaches and highlight the critical importance of early diagnosis and optimized management to mitigate the long-term impact of RMD.</p>","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":"14"},"PeriodicalIF":2.5,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12905859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence of coronary artery disease in rheumatoid arthritis patients in Palestine: a cross-sectional study.","authors":"Rami Shrouf, Aleen Aldabbas, Razan Sobeih, Talal Asafrah, Sameh Issa, Dunia Salhab, Osama Ewidat, Nuha Riyad, Mohammed Alzer'e, Abrar Khdour, Ahmad Fasfoos, Saed Atawnah","doi":"10.1186/s41927-026-00613-3","DOIUrl":"10.1186/s41927-026-00613-3","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid arthritis (RA) is a systemic inflammatory disorder associated with a significantly increased risk of cardiovascular events. This study aims to assess the prevalence of coronary artery disease (CAD) and its associated risk factors among Palestinian patients with RA, a population for which this data has been lacking.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from March to September 2024 at multiple rheumatology clinics in the West Bank, Palestine. The study included 384 patients with a confirmed RA diagnosis based on the American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria. Data were collected on demographic characteristics, traditional cardiovascular risk factors, and RA-specific factors, including disease activity measured by the Disease Activity Score 28 (DAS28) and C-reactive protein (CRP) levels. Multivariable analysis was used to identify independent predictors of CAD.</p><p><strong>Results: </strong>The prevalence of CAD in this cohort was 25.5%. Multivariable analysis revealed that CAD was independently predicted by increasing age, dyslipidemia, and a first-degree family history of CAD. Markers of systemic inflammation, specifically higher disease activity (DAS28 Prevalence Ratio = 1.309) and elevated CRP levels (PR up to 2.108 for levels > 10 mg/L), also emerged as potent and independent predictors. Furthermore, a paradoxical, non-linear association was observed with anti-CCP antibody status, where low-positive titers conferred the highest risk (PR = 1.811), and a modest inverse association with BMI was noted (PR = 0.992), consistent with the 'obesity paradox'.</p><p><strong>Conclusion: </strong>This study reveals a high prevalence of CAD among Palestinian patients with RA, driven by both traditional metabolic risk factors and RA-related systemic inflammation. The findings highlight an urgent need to integrate proactive cardiovascular disease prevention into the standard of care for RA in Palestine, recognizing RA as a cardiovascular risk-equivalent condition.</p>","PeriodicalId":9150,"journal":{"name":"BMC Rheumatology","volume":" ","pages":"15"},"PeriodicalIF":2.5,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12906049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}