Advances in research最新文献

{"title":"Fibroin Nanoparticles: Use in Drug Delivery","authors":"Masarat Bashir, Asma-Un-Nisa, Dar Junaid Bashir, N. Ganie, K. A. Dar, S. F. I. Qadri, Tariq A. Sofi, Mehak Mohi-ud-Din","doi":"10.9734/air/2024/v25i31051","DOIUrl":"https://doi.org/10.9734/air/2024/v25i31051","url":null,"abstract":"The silkworm Bombyx mori.L. is infected by various diseases viz; grasserie, flacherie, muscardine, and pebrine. Among all these diseases the grasserie causes major economic loss to the industry and is one of the main reasons for low silk productivity. It is caused by a virus known as Bombyx mori nucleopolyhedro virus (BmNPV). The impact of grasserie disease on silkworms is significant as it leads to reduced silk production and can result in economic losses for sericulture farmers. In India greater than 50% of silk cocoon crop loss is due to BmNPV [1] and in Kashmir valley, the loss is about 28-32% [2]. Silk obtained from the cocoons of silkworm Bombyx mori L. is a natural fibrous protein well known for being lightweight, having high mechanical strength, good flexibility, and luster making it ideal for the textile industry. In addition, fibroin extracted from the cocoons of domesticated silkworm Bombyx mori L. has gained growingly interest due to its excellent mechanical properties and high biocompatibility, biodegradability, inexpensiveness, and preparation flexibility [3]. These properties of silk fibroin lead to the formulation of fibroin nanoparticles (FNP’-s) which can be used to encapsulate different types of therapeutic compounds like proteins, vaccines, enzymes, etc. Fibroin has been approved as a biomaterial by the Food and Drug Administration (FDA) and has been popularly used in numerous medical applications such as sutures, tissue regeneration, coating devices, and drug delivery systems [4]. It has been studied that SF-derived curcumin nanoparticles show higher efficacy against breast cancer cells and have the potential to treat in vivo breast tumors by local, sustained, and long-term therapeutic delivery as a biodegradable system [5]. Therefore, fibroin-coated nanoparticles can be used effectively for disease management.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"65 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140229968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Ascorbic Acid, Giloy (Tinospora cordifolia) along with Various Bedding Materials on Japanese Quail Egg Quality Attributes","authors":"N. Poonia, Vijay Kumar, Garima Choudhary, A. K. Jhirwal, T. Bothra","doi":"10.9734/air/2024/v25i31050","DOIUrl":"https://doi.org/10.9734/air/2024/v25i31050","url":null,"abstract":"The study investigated the effects of giloy (Tinospora cordifolia) and ascorbic acid supplementation along with different bedding materials (sand B1, saw dust B2 and wheat straw B3) on egg shell quality of Japanese quails. A total of 432 chicks (7 day-old) of Japanese quails were divided into three equal groups (144 each) for different bedding material used and each group was further subdivided into four groups (each of 36 chicks) on the basis of dietary treatment (control T0, giloy T1, ascorbic acid T2 and combination of both T3). The current study was carried out at the Poultry unit, Livestock Farm Complex, College of Veterinary and Animal Science, Bikaner, for 24 weeks, from October 2020 to April 2021. As a result, the birds were evenly and randomly allocated into 12 treatment groups total, with 36 birds in each group. Each group was then further split into two replicates, each with 18 birds. The quails were given three different diets: a basal diet (control, T0), one supplemented with giloy 5 g/kg, another with ascorbic acid 240 mg/kg, and a combination of both in dietary treatment groups T1, T2, and T3, respectively. There was a highly significant (p<0.01) impact of adding nutrients and using different bedding materials on the Japanese quail's egg shell thickness and weight. Egg shell weight and thickness were greater in the sawdust bedding material group in the current experiment. It was discovered that there was no significant interaction on these features between nutritional supplements and various bedding materials.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140245598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthropocene Air Quality Impact on the Kolkata People","authors":"Siba Prasad Mishra, Tridib Karmakar","doi":"10.9734/air/2024/v25i31049","DOIUrl":"https://doi.org/10.9734/air/2024/v25i31049","url":null,"abstract":"Air quality is a significant concern globally, particularly in densely populated urban areas like Kolkata, pollution-wise the 2nd largest, fast-growing metropolis in India. The present study correlates to Kolkata city during the pre-Anthropocene (the 1950s) and the concurrent air quality related to human health. Investigating the impact of anthropogenic activities on air quality in Calcutta and Kolkata is relevant to understanding public health risks and environmental sustainability. \u0000The portrayal of the current air pollutants, causes, classification and measuring apparatuses recommended by the India Meteorological Department, collected from WBPCB, the levels of the parameters such as. Particulate Matter (PM2.5 and PM10), CO, CO2, NO2, O3 and SO2 etc. and analysed statistically. \u0000Air pollution has outnumbered the fatalities of other polluting agents such as waterborne, waste, radiation, and anthropogenic players in the 21st century. The novel insights into the specific effects of anthropogenic activities on air quality in Kolkata are the vulnerabilities of transportation, industry, meteorological and slum activities that are valuable. The vulnerabilities that distract ambient air quality indices have reached critical levels of air pollutants, especially particulate matter, GHG gases and NO2. \u0000 Different zones in the city are residential, commercial, shanty towns, and industrial areas. Results show levels of pollution are different in each area. Seasonal considered, the winter season is found to have the highest distraction from ambient air quality. Some suitable measures are conceptualised that will mitigate the menace of air pollution to pave the way for bringing sustainable urban health and environment development to Greater Kolkata.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"67 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140248437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recipes for Happiness: Conversations on Happiness and Well-being in the School Environment","authors":"Guilherme Adolpho Josetti Cezar, Felipe Aurélio dos Reis","doi":"10.9734/air/2024/v25i31048","DOIUrl":"https://doi.org/10.9734/air/2024/v25i31048","url":null,"abstract":"Background: Since ancient times, the debate around happiness has been present in philosophical reflections. In the face of an increasingly complex society, impacted by several crisis, the need and urgency to debate conceptualizations of happiness and well-being is evident, and educational institutions may play a relevant role in this process.\u0000Objective: Considering philosophical and current psychological perspectives on well-being, this paper seeks to analyze children’s perceptions of happiness through the analysis of an anthology of recipes for happiness created by elementary school children in a public school in Brazil.\u0000Methodology: A qualitative analysis was carried out based on the content of 15 recipes for happiness, produced by 6th grade students at a federal public school in Brazil. Content analysis was conducted associating the thematic categories of the article “children’s conceptualizations of happiness” with the ingredients of the recipes for happiness.\u0000Results: Among the corpus of recipes analyzed in the study, positive feelings were present in 86.7% of the recipes, followed by positive self (66.7%), then friendship (46.7%), and leisure (33.3%).\u0000Conclusion: The results demonstrate writing recipes for happiness can be considered an effective intervention to articulate the debate about well-being in the school environment. Furthermore, understanding children's perceptions of happiness can be important data for developing well-being policies in schools.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"184 S489","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Green Vision to Market Reality: Exploring Sustainable Initiatives and Challenges in India","authors":"Nibir Pratim Choudhury","doi":"10.9734/air/2024/v25i31047","DOIUrl":"https://doi.org/10.9734/air/2024/v25i31047","url":null,"abstract":"In the era of globalization and heightened environmental awareness, the relevance of green marketing has surged in India. This exploratory study investigates the evolution and significance of green marketing, shedding light on its golden rules and integration into the marketing mix. Emphasizing the imperative for sustainable green marketing, the study explores its objectives and delves into challenges faced by Indian companies. Recent data underscores the profitability of green marketing, propelled by consumer demand. A scrutiny of the Indian corporate sector reveals noteworthy green initiatives by key players such as H.C.L., O.N.G.C., Kansai Nerolac, Wipro, I.T.C., Tata, and Godrej. Challenges encountered include conveying new environmental concepts, managing costs, and gaining stakeholder cooperation. The study advocates aligning marketing practices with environmental considerations for holistic, eco-friendly approaches fostering sustainable growth in both business and the environment.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"49 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140258874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Audio Visual Aids to Impart Garden-Based Nutrition Education for Preschoolers","authors":"Abhina B., Beela G. K.","doi":"10.9734/air/2024/v25i31043","DOIUrl":"https://doi.org/10.9734/air/2024/v25i31043","url":null,"abstract":"Introduction: One of the most critical period in human life is the preschool years. In order to develop healthy food habits nutrition education need to be imparted at this age. There is a novel strategy to deliver nutrition education to children namely Garden-Based Nutrition Education (GBNE). Utilization of nutrition education tools can be an effective way for the delivery of GBNE. \u0000Aim: To develop PowerPoint presentation on the importance of fruits and vegetables converts to video form and a child friendly gardening video for preschool children and assess the feasibility and acceptability. \u0000Materials and Methods: Audio visual aids like power point presentation and videos were developed. Power point presentation on importance of fruits and vegetables was developed in such a way that it can reach the respondents and convey the intended message for preschool children with a total of 13 slides. \u0000A documentary child friendly gardening video was constructed having a duration of nearly seven minutes with the title “Garden Based Nutrition Education” with the intention to inculcate gardening skills among children from their early childhood years. Both the tools were developed using standardized procedures and was subjected to pre study. In order to assess the feasibility and acceptability of the developed GBNE tools it was subjected to preschool teachers/anganwadi workers and parents of preschool children. The sample consisted of 75 parents and 75 preschool teachers which was randomly selected from Kollam and Thiruvananthapuram districts of Kerala. \u0000Results: The study reveals that, both parents and teachers finds child friendly gardening video as the most feasible and acceptable tool to impart garden-based nutrition education. \u0000Discussion: Preschool children loves gardening ad watering. Child friendly gardening video is most involving and interesting in nature when compared to power point video. \u0000Conclusion: Therefore it can be concluded that power point video on importance of fruits and vegetables and child friendly gardening video can be used as effective GBNE tool to teach the significance of fruits and vegetables through gardening activities.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"11 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140413588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Design and Optimization of Fast-dissolving Oral Drug Delivery System (ODDS) of Valproic Acid (VLA) an Anti-epileptic Category Drug","authors":"Devanand Jha, Gagan Kumar Utwaliya, Kumari Sindhu, S. Kumari, Rajnish Jha, Rashmi Vais, Puja Kumari, Ravi Shankar Kumar, Archana Yadav, Rahul Kumar, Prachi Pandey, Rahul Pal, Mayank Kumar Tiwari, Vinay Kumar Rao Khadam","doi":"10.9734/air/2024/v25i21042","DOIUrl":"https://doi.org/10.9734/air/2024/v25i21042","url":null,"abstract":"Objective: Develop and optimize a fast-dissolving oral drug delivery system (ODDS) for Valproic acid (VLA), an anti-epileptic drug, using Design of Experiments (DoE).\u0000Methodology: DoE, a powerful tool for optimizing formulations, was employed to investigate the impact of various factors on the dissolution rate of VLA ODDS. Key factors studied included superdisintegrants (sodium starch glycolate, crospovidone), diluents (lactose, microcrystalline cellulose), and lubricants (magnesium stearate). A Box-Behnken design was used to create experimental runs, and the dissolution rate at 30 minutes was chosen as the response variable.\u0000Results: The DoE analysis revealed significant interactions between factors affecting the dissolution rate. The formulation containing sodium starch glycolate, lactose, and low magnesium stearate concentration exhibited the fastest dissolution rate (Q30 > 85% in 10 minutes).\u0000Conclusion: This study successfully designed and optimized a fast-dissolving ODDS for VLA using DoE. The optimized formulation offered rapid drug release, potentially improving patient compliance and therapeutic efficacy. This approach demonstrates the effectiveness of DoE in optimizing pharmaceutical formulations for enhanced performance. The findings indicated that the RSM was effectively utilized in developing valproic acid fast dispersible tablets, thus representing a significant progress in the treatment of epileptic seizures.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"65 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140419624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foliar Application of Tropical Trees Leaf Extract for Improve Growth and Yield of Blackgram [Vigna mungo (L). Hepper]","authors":"Lirin Sharath, Iyarin Thanka Mahil E., Siddu Malakannavar, Vishnuvardhan Reddy K.","doi":"10.9734/air/2024/v25i21040","DOIUrl":"https://doi.org/10.9734/air/2024/v25i21040","url":null,"abstract":"Blackgram (Vigna mungo L.), the most important pulse crop is grown throughout India. The productivity of blackgram in India is relatively low compared to the world's average productivity. Nowadays for improving productivity foliar spraying of nutrients plays a major role. The available synthetic formulations for foliar spraying are polluting and highly expensive. Hence, the leaf extracts of tropical trees can be utilized as an alternative source since they have enormous bioactive compounds able to stimulate plant growth and improve productivity without any harmful effects. Therefore, the present study was conducted on a sandy loam farm of The Indian Agriculture College, Radhapuram from March 2023 to May 2023 to evaluate the effect of leaf extracts like Moringa oleifera (Moringa), Annona squamosa (Custard apple) and Nerium oleander (Nerium) at different concentration viz., 5% and 10% on cultivation of blackgram crop, variety VBN 8. The results revealed that foliar spraying of Moringa oleifera leaf extract @ 10% + RDF significantly improves the growth components like plant height (27.87 cm and 34.6 cm at 35 DAS and 50 DAS respectively), LAI (2.87 and 4.06 at 35 DAS and 50 DAS respectively), dry matter accumulation (141 g/m2 and 266 g/m2 at 35 DAS and 50 DAS respectively), Crop growth rate (5.77 and 8.33 g/m2/day at 20 to 35 DAS, 35 to 50 DAS respectively), Relative Growth Rate (0.064, 0.042 g/g/day at 20 to 35 DAS, 35 to 50 DAS respectively) and yield attribute like average number of pods per plant (36.9) and seed yield (648 kg/ha) over other treatments and it was on par with RDF + Foliar application of Custard apple leaf extract @ 10%.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"3 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Brief Review on Recycled Aggregate Concrete","authors":"Fengxin Chen","doi":"10.9734/air/2024/v25i21041","DOIUrl":"https://doi.org/10.9734/air/2024/v25i21041","url":null,"abstract":"This paper briefly introduces the recycling and regeneration preparation of waste concrete, as well as the crushing and screening process of waste concrete blocks. The properties of crushed aggregate and the physical and mechanical properties of recycled concrete were analyzed, and the research status of compressive strength and splitting tensile strength of waste concrete at home and abroad was summarized and analyzed. Factors such as water-glue ratio, water absorption, apparent density of recycled coarse aggregate, state of recycled coarse aggregate and strength of virgin concrete will affect the strength of recycled aggregate concrete. This paper also summarizes the relationship between the splitting tensile strength of recycled aggregate concrete and the compressive strength of the cube.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"44 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140431117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breed Preference by Farmers and the Morphometric Characteristics of Sukuma Goats and a Crossbred of Malya and Sukuma Goats in Maswa District, Tanzania","authors":"B. C. Chavala, G. Kifaro, Godfrey L. Chasama","doi":"10.9734/air/2024/v25i21039","DOIUrl":"https://doi.org/10.9734/air/2024/v25i21039","url":null,"abstract":"Aims: To study farmers’ perception toward performance of crossbreds (Malya x Sukuma) relative to the indigenous Sukuma goats. \u0000Study Design: The study was of cross-sectional design employing comparative analysis. \u0000Place and Duration of Study: The study was conducted in Maswa District of Tanzania over a three weeks period. \u0000Methodology: Fifty respondents from household which were previously involved in the crossbreeding program were sampled purposively. In which they were interviewed using questionnaires on good/positive and bad/negative attributes for each genotype, then ranks of desired breed according to market price, mature body size and age of attaining mature size. Body weights and linear body measurement of mature crossbred (Malya x Sukuma) goats and pure Sukuma goats were also taken after interviewing each household respondent. Interview data were analyzed using descriptive statistics option of SPSS and body measurements were analyzed using GLM procedure of SAS. \u0000Results: The most preferred breed was crossbred goats due to their high market price, large mature body size and early age of attaining mature size. Good attributes for Sukuma goats were disease resistance (98%) and drought resistance (94%) while bad attributes were low price in the market (88%), small body size (94%) and slow growth rate (72%). Good attributes for crossbred goats were premium price in the market (92%), high growth rate (80%) and large body size (94%). Bad attributes for crossbred goats had very low frequency. The crossbred goats were larger compared to Sukuma goats. Their mature body measurements were body length (60.6±0.46 cm), heart girth (77.6±0.58 cm), height at withers (66.4±0.42 cm) and body weight (35.1±0.52 kg) for crossbred goats while corresponding mature body measurements for Sukuma goats were 49.6±0.42 cm, 65.1±0.54 cm, 56.7±0.39 cm and 21.6±0.48 kg, respectively. \u0000Conclusion: Crossbred goats were accepted by farmers due to their beneficial impact to the households’ economy.","PeriodicalId":91191,"journal":{"name":"Advances in research","volume":"141 S264","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140429219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}